Beneficial effect of galanin on insulin sensitivity in muscle of type 2 diabetic rats

Physiology and Behavior

Volumn 103, Issue 3-4, 2011, Pages 284-289

  He, Biao ^a   Shi, Mingyi ^b   Zhang, Ling ^b   Li, Guangzhi ^b   Zhang, Lingxiang ^b   Shao, Hu ^b   Li, Jian ^b   Fang, Penghua ^b   Ma, Yinping ^b   Shi, Qiaojia ^b   Sui, Yumei ^b  

^a Anhui Defence Vacation College   (China)

^b YANGZHOU UNIVERSITY   (China)

Author keywords

Diabetes; High fat diet; Insulin sensitivity; Swimming

Indexed keywords

GALANIN; GALANIN DERIVATIVE; GALANIN[1-13]BRADYKININ[2-9]AMIDE; GLUCOSE TRANSPORTER 4; INSULIN; MESSENGER RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; EXERCISE; GLUCOSE INFUSION; HINDLIMB; HORMONE ACTION; HORMONE RELEASE; IMMUNOREACTIVITY; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; INTRACELLULAR MEMBRANE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN TRANSPORT; RAT; REAL TIME POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; SWIMMING; WESTERN BLOTTING;

ANALYSIS OF VARIANCE; ANIMALS; BLOOD GLUCOSE; BRADYKININ; CELL MEMBRANE; DIABETES MELLITUS, TYPE 2; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; GALANIN; GENE EXPRESSION REGULATION; GLUCOSE CLAMP TECHNIQUE; GLUCOSE TRANSPORTER TYPE 4; INSULIN; MALE; MUSCLE, SKELETAL; PEPTIDE FRAGMENTS; PHYSICAL CONDITIONING, ANIMAL; RATS; RATS, WISTAR; RNA, MESSENGER; STREPTOZOCIN; SWIMMING;

EID: 79952809864     PISSN: 00319384     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.physbeh.2011.02.023     Document Type: Article

References (24)

1. Yuan C.S., Dey L., Xie J.T., Aung H.H. Gastric effects of galanin and its interaction with leptin on brainstem neuronal activity. J Pharmacol Exp Ther 2002, 301:488-493.
2. 2 and its new analogues on glucose-induced insulin secretion. Pol J Pharmacol 2002, 54:133-141.
3. Lang R., Gundlach A.L., Kofler B. The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease. Pharmacol Ther 2007, 115:177-207.
4. Adams A.C., Clapham J.C., Wynick D., Speakman J.R. Feeding behaviour in galanin knockout mice supports a role of galanin in fat intake and preference. J Neuroendocrinol 2008, 20:199-06.
5. Geiger P.C., Han D.H., Wright D.C., Holloszy J.O. How muscle insulin sensitivity is regulated: testing of a hypothesis. Am J Physiol Endocrinol Metab 2006, 291:E1258-E1263.
6. Amiranoff B., Lorinet A.M., Lagny-Pourmir I., Laburthe M. Mechanism of galanin-inhibited insulin release. Occurrence of a pertussis-toxin-sensitive inhibition of adenylate cyclase. Eur J Biochem 1988, 177:147-152.
7. Adeghate E., Ponery A.S. Large reduction in the number of galanin-immunoreactive cells in pancreatic islets of diabetic rats. Neuroendocrinology 2001, 13:706-710.
8. Ahren B., Pacini G., Wynick D., Wierup N., Sundler F. Loss-of-function mutation of the galanin gene is associated with perturbed islet function in mice. Endocrinology 2004, 145:3190-3196.
9. Legakis I.N. The role of galanin in metabolic disorders leading to type 2 diabetes mellitus. Drug News Perspect 2005, 18:173-177.
10. Legalkis I.N., Mantzouridis T., Mountokalakis T. Positive correlation of galanin with glucose in healthy volunteers during an oral glucose tolerance test. Horm Metab Res 2007, 39:53-55.
11. Holmberg K., Kuteeva E., Brumovsky P., Kahl U., Karlström H., Lucas G.A., et al. Generation and phenotypic characterization of a galanin overexpressing mouse. Neuroscience 2005, 133:59-77.
12. Wang S., He C., Maguire M.T., Clemmons A.L., Burrier R.E., Guzzi M.F., et al. Genomic organization and functional characterization of the mouse GALR1 galanin receptor. FEBS Lett 1997, 411:225-230.
13. Sweeney G., Keen J., Somwar R., Konrad D., Garg R., Klip A. High leptin levels acutely inhibit insulin-stimulated glucose uptake without affecting glucose transporter 4 translocation in L6 rat skeletal muscle. Endocrinology 2001, 142:4806-4812.
14. Jiang L., Shi M., Guo L., He B., Li G., Zhang L., et al. Effect of M35, a neuropeptide galanin antagonist on glucose uptake translated by glucose transporter 4 in trained rat skeletal muscle. Neurosci Lett 2009, 467:178-181.
15. Milot M., Trudeau F. Plasma galanin immunoreactivity in the rat after swimming. Physiol Behav 1997, 62:697-00.
16. Tran T.T., Gupta N., Goh T., Naigamwalla D., Chia M.C., Koohestani N., et al. Direct measure of insulin sensitivity with the hyperinsulinemic-euglycemic clamp and surrogate measures of insulin sensitivity with the oral glucose tolerance test: correlations with aberrant crypt foci promotion in rats. Cancer Epidemiol Biomark Prev 2003, 12:47-56.
17. Kristiansen S., Ramlal T., Klip A. Phosphatidylinositol 4-kinase, but not phosphatidylinositol 3-kinase, is present in GLUT4-containing vesicles isolated from rat skeletal muscle. Biochem J 1998, 335:351-356.
18. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
19. Komatsu T., Itoh F., Mikawa S., Hodate K. Gene expression of resistin in adipose tissue and mammary gland of lactating and non-lactating cows. J Endocrinol 2003, 178:R1-R5.
20. Wang H.J., Jin Y.X., Shen W., Neng J., Wu T., Li Y.J., et al. Low dose streptozotocin (STZ) combined with high energy intake can effectively induce type 2 diabetes through altering the related gene expression. Asia Pac J Clin Nutr 2007, 16:412-417.
21. Garcia-Roves P.M., Han D.H., Song Z., Jones T.E., Hucker K.A., Holloszy J.O. Prevention of glycogen supercompensation prolongs the increase in muscle GLUT4 after exercise. Am J Physiol Endocrinol Metab 2003, 285:E729-E736.
22. Holmes P.V., Yoo H.S., Dishman R.K. Voluntary exercise and clomipramine treatment elevate prepro-galanin mRNA levels in the locus coeruleus in rats. Neurosci Lett 2006, 1:1-4.
23. Augustin R. The protein family of glucose transport facilitators: it's not only about glucose after all. IUBMB Life 2010, 62:315-333.
24. Konrad D., Bilan P.J., Nawaz Z., Sweeney G., Niu W., Liu Z., et al. Need for GLUT4 activation to reach maximum effect of insulin-mediated glucose uptake in brown adipocytes isolated from GLUT4 myc-expressing mice. Diabetes 2002, 51:2719-2726.