A systematic literature review of 10 years of research on sex/gender and pain perception - Part 2: Do biopsychosocial factors alter pain sensitivity differently in women and men?

Pain

Volumn 153, Issue 3, 2012, Pages 619-635

  Racine, Mélanie ^a,b   Tousignant Laflamme, Yannick ^c   Kloda, Lorie A ^d   Dion, Dominique ^e   Dupuis, Gilles ^a,f   Choinire, Manon ^b,e  

^a UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^b CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^c UNIVERSITY OF SHERBROOKE   (Canada)

^d MCGILL UNIVERSITY   (Canada)

^e UNIVERSITÉ DE MONTRÉAL   (Canada)

^f MONTREAL HEART INSTITUTE   (Canada)

Author keywords

Biological factors; Cognitive factors; Experimental studies; Gender; Healthy subjects; Pain sensitivity; Past history; Psychological factors; Sex; Social factors; Systematic review

Indexed keywords

ANXIETY; BIOSIS; CINAHL; CLINICAL RESEARCH; COLD; DATA BASE; EMBASE; HEAT; HUMAN; HYPOALGESIA; LEISURE; MEDLINE; MYALGIA; NOCICEPTION; PAIN; PAIN ASSESSMENT; PAIN THRESHOLD; PRESSURE; PRIORITY JOURNAL; PSYCINFO; REVIEW; SYSTEMATIC REVIEW; VISCERAL PAIN; VISUAL ANALOG SCALE;

EID: 84857364743     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2011.11.026     Document Type: Article

References (208)

1. M. al'Absi, T.W. Buchanan, A. Marrero, and W.R. Lovallo Sex differences in pain perception and cardiovascular responses in persons with parental history for hypertension Pain 83 1999 331 338 (Pubitemid 29479293)
2. M. al'Absi, C.R. France, C. Ring, J. France, A. Harju, D. McIntyre, and L.E. Wittmers Nociception and baroreceptor stimulation in hypertension-prone men and women Psychophysiology 42 2005 83 91 (Pubitemid 40395417)
3. M. al'Absi, and K.L. Petersen Blood pressure but not cortisol mediates stress effects on subsequent pain perception in healthy men and women Pain 106 2003 285 295 (Pubitemid 37505876)
4. M. al'Absi, K.L. Petersen, and L.E. Wittmers Adrenocortical and hemodynamic predictors of pain perception in men and women Pain 96 2002 197 204 (Pubitemid 34270640)
5. M. al'Absi, and P.D. Rokke Can anxiety help us tolerate pain? Pain 46 1991 43 51
6. A.M. Aloisi Gonadal hormones and sex differences in pain reactivity Clin J Pain 19 2003 168 174 (Pubitemid 36578517)
7. A.M. Aloisi, and M. Bonifazi Sex hormones, central nervous system and pain Horm Behav 50 2006 1 7 (Pubitemid 43792491)
8. Z. Amit, and Z.H. Galina Stress-induced analgesia: adaptive pain suppression Physiol Rev 66 1986 1091 1120 (Pubitemid 17181299)
9. L. Arendt-Nielsen, K.A. Sluka, and H.L. Nie Experimental muscle pain impairs descending inhibition Pain 140 2008 465 471
10. P.M. Aslaksen, I.N. Myrbakk, R.S. Hoifodt, and M.A. Flaten The effect of experimenter gender on autonomic and subjective responses to pain stimuli Pain 129 2007 260 268 (Pubitemid 46754566)
11. E.E. Ayesh, T.S. Jensen, and P. Svensson Somatosensory function following painful repetitive electrical stimulation of the human temporomandibular joint and skin Exp Brain Res 179 2007 415 425 (Pubitemid 46716597)
12. L. Baad-Hansen, H.F. Poulsen, H.M. Jensen, and P. Svensson Lack of sex differences in modulation of experimental intraoral pain by diffuse noxious inhibitory controls (DNIC) Pain 116 2005 359 365 (Pubitemid 40957140)
13. A. Bandura Self-efficacy: the exercise of control 1997 Freeman New York
14. A.J. Barsky, H.M. Peekna, and J.F. Borus Somatic symptom reporting in women and men J Gen Intern Med 16 2001 266 275 (Pubitemid 32397675)
15. A.T. Beck, and R.A. Steer Beck Depression Inventory manual 1987 The Psychological Corporation San Antonio, TX
16. S.L. Bem The measurement of psychological androgyny J Consult Clin Psychol 42 1974 155 162
17. K.J. Berkley Sex differences in pain Behav Brain Sci 20 1997 371 380 (Pubitemid 28125800)
18. K.J. Berkley, S.S. Zalcman, and V.R. Simon Sex and gender differences in pain and inflammation: a rapidly maturing field Am J Physiol Regul Integr Comp Physiol 291 2006 R241 R244
19. S.F. Bernardes, E. Keogh, and M.L. Lima Bridging the gap between pain and gender research: a selective literature review Eur J Pain 12 2008 427 440 (Pubitemid 351312901)
20. F.M. Blyth, L.M. March, A.J. Brnabic, L.R. Jorm, M. Williamson, and M.J. Cousins Chronic pain in Australia: a prevalence study Pain 89 2001 127 134 (Pubitemid 32146391)
21. E.E. Bragdon, K.C. Light, N.L. Costello, A. Sigurdsson, S. Bunting, K. Bhalang, and W. Maixner Group differences in pain modulation: pain-free women compared to pain-free men and to women with TMD Pain 96 2002 227 237 (Pubitemid 34327868)
22. L. Braid, and P.M. Cahusac Decreased sensitivity to self-inflicted pain Pain 124 2006 134 139 (Pubitemid 44176204)
23. H. Breivik, B. Collett, V. Ventafridda, R. Cohen, and D. Gallacher Survey of chronic pain in Europe: prevalence, impact on daily life, and treatment Eur J Pain 10 2006 287 333
24. J.L. Brown, D. Sheffield, M.R. Leary, and M.E. Robinson Social support and experimental pain Psychosom Med 65 2003 276 283 (Pubitemid 36359339)
25. S. Bruehl, J.A. McCubbin, and R.N. Harden Theoretical review: altered pain regulatory systems in chronic pain Neurosci Biobehav Rev 23 1999 877 890 (Pubitemid 29458893)
26. B.E. Cairns, J.W. Hu, L. Arendt-Nielsen, B.J. Sessle, and P. Svensson Sex-related differences in human pain and rat afferent discharge evoked by injection of glutamate into the masseter muscle J Neurophysiol 86 2001 782 791 (Pubitemid 32738567)
27. T.S. Campbell, J.W. Hughes, S.S. Girdler, W. Maixner, and A. Sherwood Relationship of ethnicity, gender, and ambulatory blood pressure to pain sensitivity: effects of individualized pain rating scales J Pain 5 2004 183 191 (Pubitemid 38885679)
28. L.E. Carter, D.W. McNeil, K.E. Vowles, J.T. Sorrell, C.L. Turk, B.J. Ries, and D.R. Hopko Effects of emotion on pain reports, tolerance and physiology Pain Res Manag 7 2002 21 30 (Pubitemid 34552283)
29. Centre for Reviews and Dissemination. Systematic reviews: CRD's guidance for undertaking reviews in healthcare. York, UK: University of York; 2009.
30. C.C. Chao, S.T. Hsieh, M.J. Chiu, M.T. Tseng, and Y.C. Chang Effects of aging on contact heat-evoked potentials: the physiological assessment of thermal perception Muscle Nerve 36 2007 30 38
31. C.R. Chapman, S. Oka, D.H. Bradshaw, R.C. Jacobson, and G.W. Donaldson Phasic pupil dilation response to noxious stimulation in normal volunteers: relationship to brain evoked potentials and pain report Psychophysiology 36 1999 44 52 (Pubitemid 29044455)
32. L.S. Chesterton, P. Barlas, N.E. Foster, G.D. Baxter, and C.C. Wright Gender differences in pressure pain threshold in healthy humans Pain 101 2003 259 266 (Pubitemid 36175520)
33. R. Chou, S. Norris, S. Carson, and B.K.S. Chan Drug class review on drugs for neuropathic pain 2009 Oregon Health and Science University Portland, OR
34. M. Clarke The QUORUM statement Lancet 355 2000 756 757 (Pubitemid 30107647)
35. S. Cohen, T. Kamarck, and R. Mermelstein A global measure of perceived stress J Health Soc Behav 24 1983 385 396
36. D.B. Cook, P.J. O'Connor, S.E. Oliver, and Y. Lee Sex differences in naturally occurring leg muscle pain and exertion during maximal cycle ergometry Int J Neurosci 95 1998 183 202 (Pubitemid 28434091)
37. R.M. Craft Sex differences in drug- and non-drug-induced analgesia Life Sci 72 2003 2675 2688 (Pubitemid 36385075)
38. R.M. Craft Modulation of pain by estrogens Pain 132 2007 S3 S12
39. R.M. Craft, J.S. Mogil, and A.M. Aloisi Sex differences in pain and analgesia: the role of gonadal hormones Eur J Pain 8 2004 397 411 (Pubitemid 39485765)
40. E.A. Dannecker, K.F. Koltyn, J.L. Riley III, and M.E. Robinson Sex differences in delayed onset muscle soreness J Sports Med Phys Fitness 43 2003 78 84 (Pubitemid 36505749)
41. T.T. Dao, and L. LeResche Gender differences in pain J Orofac Pain 14 2000 169 184
42. R. Defrin, A. Benstein-Sheraizin, A. Bezalel, O. Mantzur, and L. Arendt-Nielsen The spatial characteristics of the painful thermal grill illusion Pain 138 2008 577 586
43. R. Defrin, G. Pope, and K.D. Davis Interactions between spatial summation, 2-point discrimination and habituation of heat pain Eur J Pain 12 2008 900 909
44. S.W. Derbyshire, T.E. Nichols, L. Firestone, D.W. Townsend, and A.K. Jones Gender differences in patterns of cerebral activation during equal experience of painful laser stimulation J Pain 3 2002 401 411 (Pubitemid 35176462)
45. K.E. Dixon, B.E. Thorn, and L.C. Ward An evaluation of sex differences in psychological and physiological responses to experimentally-induced pain: a path analytic description Pain 112 2004 188 196 (Pubitemid 39371035)
46. W. Drobek, J. Schoenaers, and A. De Laat Hormone-dependent fluctuations of pressure pain threshold and tactile threshold of the temporalis and masseter muscle J Oral Rehabil 29 2002 1042 1051 (Pubitemid 41697907)
47. B.R. Dworkin, R.J. Filewich, N.E. Miller, N. Craigmyle, and T.G. Pickering Baroreceptor activation reduces reactivity to noxious stimulation: implications for hypertension Science 205 1979 1299 1301 (Pubitemid 10239864)
48. R.R. Edwards, J.A. Haythornthwaite, M.J. Sullivan, and R.B. Fillingim Catastrophizing as a mediator of sex differences in pain: differential effects for daily pain versus laboratory-induced pain Pain 111 2004 335 341 (Pubitemid 39201155)
49. M. Egger, D.G. Davey Smith, and D.G. Altman Systematic reviews in health care: meta analysis in context 2001 BMJ Books London
50. G. Essick, S. Guest, E. Martinez, C. Chen, and F. McGlone Site-dependent and subject-related variations in perioral thermal sensitivity Somatosens Mot Res 21 2004 159 175 (Pubitemid 40075607)
51. R. Fillingim Sex, gender, and pain vol. 17 2001 IASP Press Seattle, WA
52. R.B. Fillingim Sex, gender, and pain: women and men really are different Curr Rev Pain 4 2000 24 30
53. R.B. Fillingim Individual differences in pain responses Curr Rheumatol Rep 7 2005 342 347
54. R.B. Fillingim, A.D. Browning, T. Powell, and R.A. Wright Sex differences in perceptual and cardiovascular responses to pain: the influence of a perceived ability manipulation J Pain 3 2002 439 445 (Pubitemid 35462619)
55. R.B. Fillingim, and R.R. Edwards The association of hormone replacement therapy with experimental pain responses in postmenopausal women Pain 92 2001 229 234 (Pubitemid 32367954)
56. R.B. Fillingim, and R.R. Edwards Is self-reported childhood abuse history associated with pain perception among healthy young women and men? Clin J Pain 21 2005 387 397 (Pubitemid 41233133)
57. R.B. Fillingim, R.R. Edwards, and T. Powell The relationship of sex and clinical pain to experimental pain responses Pain 83 1999 419 425
58. R.B. Fillingim, R.R. Edwards, and T. Powell Sex-dependent effects of reported familial pain history on recent pain complaints and experimental pain responses Pain 86 2000 87 94 (Pubitemid 30211707)
59. R.B. Fillingim, L. Kaplan, R. Staud, T.J. Ness, T.L. Glover, C.M. Campbell, J.S. Mogil, and M.R. Wallace The A118G single nucleotide polymorphism of the mu-opioid receptor gene (OPRM1) is associated with pressure pain sensitivity in humans J Pain 6 2005 159 167 (Pubitemid 40365019)
60. R.B. Fillingim, C.D. King, M.C. Ribeiro-Dasilva, B. Rahim-Williams, and J.L. Riley III Sex, gender, and pain: a review of recent clinical and experimental findings J Pain 10 2009 447 485
61. R.B. Fillingim, and W. Maixner Gender differences in the responses to noxious stimuli Pain Forum 4 1995 209 221 (Pubitemid 26049257)
62. R.B. Fillingim, W. Maixner, S. Kincaid, and S. Silva Sex differences in temporal summation but not sensory-discriminative processing of thermal pain Pain 75 1998 121 127 (Pubitemid 28254863)
63. R.B. Fillingim, and T.J. Ness Sex-related hormonal influences on pain and analgesic responses Neurosci Biobehav Rev 24 2000 485 501 (Pubitemid 30243063)
64. C.R. France, and S. Suchowiecki A comparison of diffuse noxious inhibitory controls in men and women Pain 81 1999 77 84 (Pubitemid 29199903)
65. M. Frot, J.S. Feine, and M.C. Bushnell Sex differences in pain perception and anxiety. A psychophysical study with topical capsaicin Pain 108 2004 230 236 (Pubitemid 38353045)
66. J.P. Garofalo, C. Lawler, R. Robinson, M. Morgan, and T. Kenworthy-Heinige The role of mood states underlying sex differences in the perception and tolerance of pain Pain Pract 6 2006 186 196 (Pubitemid 44193946)
67. P. Gazerani, O.K. Andersen, and L. Arendt-Nielsen A human experimental capsaicin model for trigeminal sensitization. Gender-specific differences Pain 118 2005 155 163 (Pubitemid 41566594)
68. P. Gazerani, O.K. Andersen, and L. Arendt-Nielsen Site-specific, dose-dependent, and sex-related responses to the experimental pain model induced by intradermal injection of capsaicin to the foreheads and forearms of healthy humans J Orofac Pain 21 2007 289 302
69. P. Gazerani, K. Wang, B.E. Cairns, P. Svensson, and L. Arendt-Nielsen Effects of subcutaneous administration of glutamate on pain, sensitization and vasomotor responses in healthy men and women Pain 124 2006 338 348 (Pubitemid 44397257)
70. H.Y. Ge, P. Madeleine, and L. Arendt-Nielsen Sex differences in temporal characteristics of descending inhibitory control: an evaluation using repeated bilateral experimental induction of muscle pain Pain 110 2004 72 78 (Pubitemid 38953270)
71. H.Y. Ge, P. Madeleine, and L. Arendt-Nielsen Gender differences in pain modulation evoked by repeated injections of glutamate into the human trapezius muscle Pain 113 2005 134 140 (Pubitemid 40038454)
72. H.Y. Ge, P. Madeleine, B.E. Cairns, and L. Arendt-Nielsen Hypoalgesia in the referred pain areas after bilateral injections of hypertonic saline into the trapezius muscles of men and women: a potential experimental model of gender-specific differences Clin J Pain 22 2006 37 44 (Pubitemid 44378561)
73. S.Z. George, E.A. Dannecker, and M.E. Robinson Fear of pain, not pain catastrophizing, predicts acute pain intensity, but neither factor predicts tolerance or blood pressure reactivity: an experimental investigation in pain-free individuals Eur J Pain 10 2006 457 465 (Pubitemid 43767695)
74. S. Ghione Hypertension-associated hypalgesia. Evidence in experimental animals and humans, pathophysiological mechanisms, and potential clinical consequences Hypertension 28 1996 494 504 (Pubitemid 26296057)
75. K. Gijsbers, and F. Nicholson Experimental pain thresholds influenced by sex of experimenter Percept Mot Skills 101 2005 803 807 (Pubitemid 43569063)
76. J. Goldberg, R. Alon, M. Weisenberg, and K.G. Gotestam Influence of success and failure on pain tolerance Eur J Psychiatry 14 2000 171 179 (Pubitemid 30641950)
77. M. Granot, Y. Granovsky, E. Sprecher, R.R. Nir, and D. Yarnitsky Contact heat-evoked temporal summation: tonic versus repetitive-phasic stimulation Pain 122 2006 295 305 (Pubitemid 43729473)
78. M. Granot, I. Weissman-Fogel, Y. Crispel, D. Pud, Y. Granovsky, E. Sprecher, and D. Yarnitsky Determinants of endogenous analgesia magnitude in a diffuse noxious inhibitory control (DNIC) paradigm: do conditioning stimulus painfulness, gender and personality variables matter? Pain 136 2008 142 149 (Pubitemid 351491376)
79. J.D. Greenspan, R.M. Craft, L. LeResche, L. Arendt-Nielsen, K.J. Berkley, R.B. Fillingim, M.S. Gold, A. Holdcroft, S. Lautenbacher, E.A. Mayer, J.S. Mogil, A.Z. Murphy, and R.J. Traub Studying sex and gender differences in pain and analgesia: a consensus report Pain 132 2007 S26 S45
80. B.A. Hastie, J.L. Riley III, M.E. Robinson, T. Glover, C.M. Campbell, R. Staud, and R.B. Fillingim Cluster analysis of multiple experimental pain modalities Pain 116 2005 227 237 (Pubitemid 40957126)
81. S.G. Helfer, and J.A. McCubbin Does gender affect the relation between blood pressure and pain sensitivity? Int J Behav Med 8 2001 220 229 (Pubitemid 32954974)
82. B. Hellström, and U. Lundberg Pain perception to the cold presser test during the menstrual cycle in relation to estrogen levels and a comparison with men Integr Physiol Behav Sci 35 2000 132 141
83. L.A. Henderson, S.C. Gandevia, and V.G. Macefield Gender differences in brain activity evoked by muscle and cutaneous pain: a retrospective study of single-trial fMRI data Neuroimage 39 2008 1867 1876
84. A.T. Hirsh, S.Z. George, J.E. Bialosky, and M.E. Robinson Fear of pain, pain catastrophizing, and acute pain perception: relative prediction and timing of assessment J Pain 9 2008 806 812
85. A.R. Hobson, P.L. Furlong, S.F. Worthen, A. Hillebrand, G.R. Barnes, K.D. Singh, and Q. Aziz Real-time imaging of human cortical activity evoked by painful esophageal stimulation Gastroenterology 128 2005 610 619 (Pubitemid 40585363)
86. M.K. Hoeger Bement, J. Dicapo, R. Rasiarmos, and S.K. Hunter Dose response of isometric contractions on pain perception in healthy adults Med Sci Sports Exerc 40 2008 1880 1889
87. A. Holdcroft Integrating the dimensions of sex and gender into basic life sciences research: methodologic and ethical issues Gend Med 4 2007 S64 S74
88. A. Holdcroft, and K.J. Berkley Sex and gender differences in pain and its relief S.B. McMahon, M. Koltzenburg, Wall and Melzack's textbook of pain 2006 Elsevier Churchill Livingstone London, UK 1181 1197
89. H. Isselee, A. De Laat, K. Bogaerts, and R. Lysens Long-term fluctuations of pressure pain thresholds in healthy men, normally menstruating women and oral contraceptive users Eur J Pain 5 2001 27 37 (Pubitemid 32661925)
90. T. Jackson Interpersonal transactions and responses to cold pressor pain among Australian women and men Sex Roles 56 2007 55 62
91. T. Jackson, T. Iezzi, H. Chen, S. Ebnet, and K. Eglitis Gender, interpersonal transactions, and the perception of pain: an experimental analysis J Pain 6 2005 228 236 (Pubitemid 40488800)
92. T. Jackson, T. Iezzi, J. Gunderson, T. Nagasaka, and A. Fritch Gender differences in pain perception: the mediating role of self-efficacy beliefs Sex Roles 47 2002 561 568
93. S.A. Janssen, P. Spinhoven, and J.F. Brosschot Experimentally induced anger, cardiovascular reactivity, and pain sensitivity J Psychosom Res 51 2001 479 485 (Pubitemid 32904177)
94. M.T. Jensen, and K.L. Petersen Gender differences in pain and secondary hyperalgesia after heat/capsaicin sensitization in healthy volunteers J Pain 7 2006 211 217 (Pubitemid 43324997)
95. A. Jones, H. Spindler, M.M. Jorgensen, and R. Zachariae The effect of situation-evoked anxiety and gender on pain report using the cold pressor test Scand J Psychol 43 2002 307 313
96. A. Jones, and R. Zachariae Gender, anxiety, and experimental pain sensitivity: an overview J Am Med Womens Assoc 57 2002 91 94
97. A. Jones, and R. Zachariae Investigation of the interactive effects of gender and psychological factors on pain response Br J Health Psychol 9 2004 405 418 (Pubitemid 39277411)
98. A. Jones, R. Zachariae, and L. Arendt-Nielsen Dispositional anxiety and the experience of pain: gender-specific effects Eur J Pain 7 2003 387 395 (Pubitemid 37101778)
99. I. Kallai, A. Barke, and U. Voss The effects of experimenter characteristics on pain reports in women and men Pain 112 2004 142 147 (Pubitemid 39371029)
100. R. Kenntner-Mabiala, S. Gorges, G.W. Alpers, A.C. Lehmann, and P. Pauli Musically induced arousal affects pain perception in females but not in males: a psychophysiological examination Biol Psychol 75 2007 19 23 (Pubitemid 46400967)
101. R. Kenntner-Mabiala, P. Weyers, and P. Pauli Independent effects of emotion and attention on sensory and affective pain perception Cogn Emot 21 2007 1615 1629 (Pubitemid 350120423)
102. E. Keogh, C. Barlow, C. Mounce, and F.W. Bond Assessing the relationship between cold pressor pain responses and dimensions of the anxiety sensitivity profile in healthy men and women Cogn Behav Ther 35 2006 198 206 (Pubitemid 46002444)
103. E. Keogh, and J. Birkby The effect of anxiety sensitivity and gender on the experience of pain Cogn Emot 13 1999 813 829
104. E. Keogh, F.W. Bond, R. Hanmer, and J. Tilston Comparing acceptance- and control-based coping instructions on the cold-pressor pain experiences of healthy men and women Eur J Pain 9 2005 591 598 (Pubitemid 41222323)
105. E. Keogh, K. Hatton, and D. Ellery Avoidance versus focused attention and the perception of pain: differential effects for men and women Pain 85 2000 225 230 (Pubitemid 30110763)
106. E. Keogh, and M. Herdenfeldt Gender, coping and the perception of pain Pain 97 2002 195 201 (Pubitemid 34607216)
107. E. Keogh, C. Mounce, and M. Brosnan Can a sexually dimorphic index of prenatal hormonal exposure be used to examine cold pressor pain perception in men and women? Eur J Pain 11 2007 231 236 (Pubitemid 44820902)
108. M.K. Kern, S. Jaradeh, R.C. Arndorfer, A. Jesmanowicz, J. Hyde, and R. Shaker Gender differences in cortical representation of rectal distension in healthy humans Am J Physiol Gastrointest Liver Physiol 281 2001 G1512 G1523
109. H. Kim, J.K. Neubert, J.S. Rowan, J.S. Brahim, M.J. Iadarola, and R.A. Dionne Comparison of experimental and acute clinical pain responses in humans as pain phenotypes J Pain 5 2004 377 384 (Pubitemid 39410106)
110. H. Kim, J.K. Neubert, A. San Miguel, K. Xu, R.K. Krishnaraju, M.J. Iadarola, D. Goldman, and R.A. Dionne Genetic influence on variability in human acute experimental pain sensitivity associated with gender, ethnicity and psychological temperament Pain 109 2004 488 496 (Pubitemid 38638726)
111. K.F. Koltyn, M.R. Trine, A.J. Stegner, and D.A. Tobar Effect of isometric exercise on pain perception and blood pressure in men and women Med Sci Sports Exerc 33 2001 282 290 (Pubitemid 32142995)
112. W.J. Kowalczyk, S.M. Evans, A.M. Bisaga, M.A. Sullivan, and S.D. Comer Sex differences and hormonal influences on response to cold pressor pain in humans J Pain 7 2006 151 160 (Pubitemid 43324990)
113. M. Kunz, A. Gruber, and S. Lautenbacher Sex differences in facial encoding of pain J Pain 7 2006 915 928 (Pubitemid 44854738)
114. R.H. LaMotte, C.N. Shain, D.A. Simone, and E.F. Tsai Neurogenic hyperalgesia: psychophysical studies of underlying mechanisms J Neurophysiol 66 1991 190 211
115. S. Lautenbacher, M. Kunz, and S. Burkhardt The effects of DNIC-type inhibition on temporal summation compared to single pulse processing: does sex matter? Pain 140 2008 429 435
116. S. Lautenbacher, J. Nielsen, T. Andersen, and L. Arendt-Nielsen Spatial summation of heat pain in males and females Somatosens Mot Res 18 2001 101 105 (Pubitemid 32664608)
117. D. Le Bars, A.H. Dickenson, and J.M. Besson Diffuse noxious inhibitory controls (DNIC). I. Effects on dorsal horn convergent neurones in the rat Pain 6 1979 283 304 (Pubitemid 9205924)
118. D. Le Bars, L. Villanueva, D. Bouhassira, and J.C. Willer Diffuse noxious inhibitory controls (DNIC) in animals and in man Patol Fiziol Eksp Ter 1992 55 65
119. J. Li, D.A. Simone, and A.A. Larson Windup leads to characteristics of central sensitization Pain 79 1999 75 82 (Pubitemid 29012438)
120. H. Logan, S. Lutgendorf, P. Rainville, D. Sheffield, K. Iverson, and D. Lubaroff Effects of stress and relaxation on capsaicin-induced pain J Pain 2 2001 160 170 (Pubitemid 32550238)
121. H.L. Logan, and J.J. Gedney Sex differences in the long-term stability of forehead cold pressor pain J Pain 5 2004 406 412 (Pubitemid 39410109)
122. S. Lovibond, and P. Lovibond Manual for the depression anxiety stress scales 1995 Psychological Foundation Sydney, Australia
123. D. Lowery, R.B. Fillingim, and R.A. Wright Sex differences and incentive effects on perceptual and cardiovascular responses to cold pressor pain Psychosom Med 65 2003 284 291 (Pubitemid 36359340)
124. M. Lugo, G. Isturiz, C. Lara, N. Garcia, and A. Eblen-Zaijur Sensory lateralization in pain subjective perception for noxious heat stimulus Somatosens Mot Res 19 2002 207 212
125. J.N. Lundström, J. Frasnelli, M. Larsson, and T. Hummel Sex differentiated responses to intranasal trigeminal stimuli Int J Psychophysiol 57 2005 181 186 (Pubitemid 41139880)
126. C. Mackay, T. Cox, G. Burrows, and T. Lazzerini An inventory for the measurement of self-reported stress and arousal Br J Soc Clin Psychol 17 1978 283 284 (Pubitemid 9000796)
127. S. Marchand, and P. Arsenault Odors modulate pain perception: a gender-specific effect Physiol Behav 76 2002 251 256 (Pubitemid 34614538)
128. L.E. McClelland, and J.A. McCubbin Social influence and pain response in women and men J Behav Med 31 2008 413 420
129. D.M. McNair, M. Lorr, and L.F. Droppleman POMS manual - profile of mood questionnaire 1992 Educational and Industrial Testing Service, Inc. San Diego, CA
130. M. Meana The meeting of pain and depression: comorbidity in women Can J Psychiatry 43 1998 893 899 (Pubitemid 29173296)
131. L.A. Mitchell, R.A. MacDonald, and E.E. Brodie A comparison of the effects of preferred music, arithmetic and humour on cold pressor pain Eur J Pain 10 2006 343 351
132. J.S. Mogil Sex, gender and pain F. Cervero, T.S. Jensen, Pain: handbook of clinical neurology vol. 81 2006 Elsevier Edinburgh 325 341
133. E.A. Moulton, M.L. Keaser, R.P. Gullapalli, R. Maitra, and J.D. Greenspan Sex differences in the cerebral BOLD signal response to painful heat stimuli Am J Physiol Regul Integr Comp Physiol 291 2006 R257 R267
134. C.D. Myers, J.L. Riley III, and M.E. Robinson Psychosocial contributions to sex-correlated differences in pain Clin J Pain 19 2003 225 232 (Pubitemid 36828736)
135. C.D. Myers, M.E. Robinson, J.L. Riley III, and D. Sheffield Sex, gender, and blood pressure: contributions to experimental pain report Psychosom Med 63 2001 545 550 (Pubitemid 32695134)
136. B.D. Naliboff, D. Benton, G.F. Solomon, J.E. Morley, J.L. Fahey, E.T. Bloom, T. Makinodan, and S.L. Gilmore Immunological changes in young and old adults during brief laboratory stress Psychosom Med 53 1991 121 132
137. S. Nayak, S.C. Shiflette, S. Esheu, and F.M. Levine Culture and gender effects in pain beliefs and the prediction of pain tolerance Cross Cult Res 34 2000 135 151
138. H. Nie, L. Arendt-Nielsen, H. Andersen, and T. Graven-Nielsen Temporal summation of pain evoked by mechanical stimulation in deep and superficial tissue J Pain 6 2005 348 355 (Pubitemid 40804339)
139. H. Nie, A. Kawczynski, P. Madeleine, and L. Arendt-Nielsen Delayed onset muscle soreness in neck/shoulder muscles Eur J Pain 9 2005 653 660 (Pubitemid 41503561)
140. C.S. Nielsen, R. Staud, and D.D. Price Individual differences in pain sensitivity: measurement, causation, and consequences J Pain 10 2009 231 237
141. I. Nyklicek, A.J. Vingerhoets, and G.L. Van Heck Hypertension and pain sensitivity: effects of gender and cardiovascular reactivity Biol Psychol 50 1999 127 142 (Pubitemid 29248814)
142. M.M. Ohayon Specific characteristics of the pain/depression association in the general population J Clin Psychiatry 65 2004 5 9
143. M.M. Ohayon, and A.F. Schatzberg Using chronic pain to predict depressive morbidity in the general population Arch Gen Psychiatry 60 2003 39 47 (Pubitemid 36070863)
144. P.E. Paulson, S. Minoshima, T.J. Morrow, and K.L. Casey Gender differences in pain perception and patterns of cerebral activation during noxious heat stimulation in humans Pain 76 1998 223 229 (Pubitemid 28304960)
145. A. Peddireddy, K. Wang, P. Svensson, and L. Arendt-Nielsen Effect of experimental posterior temporalis muscle pain on human brainstem reflexes Clin Neurophysiol 116 2005 1611 1620 (Pubitemid 40805442)
146. J. Pedersen, H. Reddy, P. Funch-Jensen, L. Arendt-Nielsen, H. Gregersen, and A.M. Drewes Differences between male and female responses to painful thermal and mechanical stimulation of the human esophagus Dig Dis Sci 49 2004 1065 1074 (Pubitemid 39178067)
147. L. Pinerua-Shuhaibar, D. Prieto-Rincon, A. Ferrer, E. Bonilla, W. Maixner, and H. Suarez-Roca Reduced tolerance and cardiovascular response to ischemic pain in minor depression J Affect Disord 56 1999 119 126 (Pubitemid 30058214)
148. O. Plesh, D.A. Curtis, L.J. Hall, and A. Miller Gender difference in jaw pain induced by clenching J Oral Rehabil 25 1998 258 263 (Pubitemid 128705355)
149. G.J. Pool, A.F. Schwegler, B.R. Theodore, and P.N. Fuchs Role of gender norms and group identification on hypothetical and experimental pain tolerance Pain 129 2007 122 129 (Pubitemid 46551375)
150. A. Popescu, L. LeResche, E.L. Truelove, and M.T. Drangsholt Gender differences in pain modulation by diffuse noxious inhibitory controls: a systematic review Pain 150 2010 309 318
151. M.S. Poudevigne, P.J. O'Connor, and J.D. Pasley Lack of both sex differences and influence of resting blood pressure on muscle pain intensity Clin J Pain 18 2002 386 393 (Pubitemid 35291580)
152. D.D. Price, R.L. Hayes, M. Ruda, and R. Dubner Spatial and temporal transformations of input to spinothalamic tract neurons and their relation to somatic sensations J Neurophysiol 41 1978 933 947 (Pubitemid 8392567)
153. D.D. Price, J.W. Hu, R. Dubner, and R.H. Gracely Peripheral suppression of first pain and central summation of second pain evoked by noxious heat pulses Pain 3 1977 57 68 (Pubitemid 8048890)
154. D. Pud, E. Sprecher, and D. Yarnitsky Homotopic and heterotopic effects of endogenous analgesia in healthy volunteers Neurosci Lett 380 2005 209 213 (Pubitemid 40616081)
155. R.L. Quiton, and J.D. Greenspan Sex differences in endogenous pain modulation by distracting and painful conditioning stimulation Pain 132 2007 S134 S149
156. R.L. Quiton, and J.D. Greenspan Across- and within-session variability of ratings of painful contact heat stimuli Pain 137 2008 245 256 (Pubitemid 351853288)
157. M. Racine, Y. Tousignant-Laflamme, L.A. Kloda, D. Dion, G. Dupuis, and M. Choiniere A systematic literature review of 10 years of research on sex/gender and experimental pain perception - Part 1: are there really differences between women and men? Pain 153 2012 602 618
158. A. Randich, and W. Maixner Interactions between cardiovascular and pain regulatory systems Neurosci Biobehav Rev 8 1984 343 367 (Pubitemid 14023414)
159. S. Reiss, R.A. Peterson, D.M. Gursky, and R.J. McNally Anxiety sensitivity, anxiety frequency and the prediction of fearfulness Behav Res Ther 24 1986 1 8 (Pubitemid 16207745)
160. J.L. Rhudy, and M.W. Meagher Noise stress and human pain thresholds: divergent effects in men and women J Pain 2 2001 57 64 (Pubitemid 32127449)
161. J.L. Riley III, M.E. Robinson, E.A. Wise, C.D. Myers, and R.B. Fillingim Sex differences in the perception of noxious experimental stimuli: a meta-analysis Pain 74 1998 181 187 (Pubitemid 28081604)
162. J.L. Riley III, M.E. Robinson, E.A. Wise, and D.D. Price A meta-analytic review of pain perception across the menstrual cycle Pain 81 1999 225 235 (Pubitemid 29257893)
163. M.E. Robinson, C.M. Gagnon, J.L. Riley III, and D.D. Price Altering gender role expectations: effects on pain tolerance, pain threshold, and pain ratings J Pain 4 2003 284 288 (Pubitemid 36807909)
164. M.E. Robinson, J.L. Riley III, and C.D. Myers Psychosocial contributions to sex-related differences in pain responses R.B. Fillingim, Sex, gender, and pain 2001 IASP Press Seattle, WA 41 68
165. M.E. Robinson, J.L. Riley III, C.D. Myers, R.K. Papas, E.A. Wise, L.B. Waxenberg, and R.B. Fillingim Gender role expectations of pain: relationship to sex differences in pain J Pain 2 2001 251 257 (Pubitemid 32976809)
166. M.E. Robinson, and E.A. Wise Prior pain experience: influence on the observation of experimental pain in men and women J Pain 5 2004 264 269 (Pubitemid 38859680)
167. M.E. Robinson, E.A. Wise, C. Gagnon, R.B. Fillingim, and D.D. Price Influences of gender role and anxiety on sex differences in temporal summation of pain J Pain 5 2004 77 82 (Pubitemid 38850178)
168. G.B. Rollman, J. Abdel-Shaheed, J.M. Gillespie, and K.S. Jones Does past pain influence current pain: biological and psychosocial models of sex differences Eur J Pain 8 2004 427 433 (Pubitemid 39485767)
169. J.D. Rollnik, U. Schneider, S. Siggelkow, N. Schmitz, and J. Kugler Gender differences in cardiovascular responses to sphygmomanometric measurements J Psychophysiol 15 2001 43 46 (Pubitemid 32622058)
170. A. Rosen, A. Feldreich, N. Dabirian, and M. Ernberg Effect of heterotopic noxious conditioning stimulation on electrical and pressure pain thresholds in two different anatomical regions Acta Odontol Scand 66 2008 181 188 (Pubitemid 351882500)
171. A.K. Rosenstiel, and F.J. Keefe The use of coping strategies in chronic low back pain patients: relationship to patient characteristics and current adjustment Pain 17 1983 33 44 (Pubitemid 13004472)
172. S.D. Sanford, B.C. Kersh, B.E. Thorn, M.A. Rich, and L.C. Ward Psychosocial mediators of sex differences in pain responsivity J Pain 3 2002 58 64 (Pubitemid 34163492)
173. E. Sarlani, E.G. Grace, M.A. Reynolds, and J.D. Greenspan Sex differences in temporal summation of pain and aftersensations following repetitive noxious mechanical stimulation Pain 109 2004 115 123 (Pubitemid 38479777)
174. E. Sarlani, and J.D. Greenspan Gender differences in temporal summation of mechanically evoked pain Pain 97 2002 163 169 (Pubitemid 34603319)
175. M. Serrao, P. Rossi, G. Sandrini, L. Parisi, G.A. Amabile, G. Nappi, and F. Pierelli Effects of diffuse noxious inhibitory controls on temporal summation of the RIII reflex in humans Pain 112 2004 353 360 (Pubitemid 39550736)
176. J.J. Sherman, and L. LeResche Does experimental pain response vary across the menstrual cycle? A methodological review Am J Physiol Regul Integr Comp Physiol 291 2006 R245 R256
177. Y.R. Smith, C.S. Stohler, T.E. Nichols, J.A. Bueller, R.A. Koeppe, and J.K. Zubieta Pronociceptive and antinociceptive effects of estradiol through endogenous opioid neurotransmission in women J Neurosci 26 2006 5777 5785 (Pubitemid 44315270)
178. A.L. Soetanto, J.W. Chung, and T.K. Wong Are there gender differences in pain perception? J Neurosci Nurs 38 2006 172 176
179. J.T. Spence, R.L. Helmreich, and C.K. Holahan Negative and positive components of psychological masculinity and femininity and their relationships to self-reports of neurotic and acting out behaviors J Pers Soc Psychol 37 1979 1673 1682
180. C.D. Spielberger, R. Gorusch, R.E. Lushene, P.R. Vagg, and G.A. Jacobs Manual for the State-Trait Anxiety Inventory (Form Y1) 1983 Consulting Psychologists Press Palo Alto, CA
181. R. Staud, M.E. Robinson, C.J. Vierck Jr., and D.D. Price Diffuse noxious inhibitory controls (DNIC) attenuate temporal summation of second pain in normal males but not in normal females or fibromyalgia patients Pain 101 2003 167 174 (Pubitemid 36044664)
182. W.F. Sternberg, D. Bailin, M. Grant, and R.H. Gracely Competition alters the perception of noxious stimuli in male and female athletes Pain 76 1998 231 238 (Pubitemid 28304961)
183. W.F. Sternberg, C. Bokat, L. Kass, A. Alboyadjian, and R.H. Gracely Sex-dependent components of the analgesia produced by athletic competition J Pain 2 2001 65 74 (Pubitemid 32127450)
184. W.F. Sternberg, and J.C. Liebeskind The analgesic response to stress: genetic and gender considerations Eur J Anaesthesiol Suppl 10 1995 14 17
185. A. Streff, L.K. Kuehl, G. Michaux, and F. Anton Differential physiological effects during tonic painful hand immersion tests using hot and ice water Eur J Pain 14 2010 266 272
186. M.J. Sullivan, D.A. Tripp, and S. Darcy Gender differences in pain and pain behavior: the role of catastrophizing Cognit Ther Res 24 2000 121 134 (Pubitemid 30137038)
187. M.J.L. Sullivan, S. Bishop, and J. Pivik The Pain Catastrophizing Scale: development and validation Psychol Assess 7 1995 524 532 (Pubitemid 26017352)
188. P. Svensson, B.E. Cairns, K. Wang, J.W. Hu, T. Graven-Nielsen, L. Arendt-Nielsen, and B.J. Sessle Glutamate-evoked pain and mechanical allodynia in the human masseter muscle Pain 101 2003 221 227 (Pubitemid 36173762)
189. T. Thompson, E. Keogh, C.C. French, and R. Davis Anxiety sensitivity and pain: generalisability across noxious stimuli Pain 134 2008 187 196 (Pubitemid 350251015)
190. B.E. Thorn, K.L. Clements, L.C. Ward, K.E. Dixon, B.C. Kersh, J.L. Boothby, and W.F. Chaplin Personality factors in the explanation of sex differences in pain catastrophizing and response to experimental pain Clin J Pain 20 2004 275 282 (Pubitemid 39108839)
191. Y. Tousignant-Laflamme, and S. Marchand Excitatory and inhibitory pain mechanisms during the menstrual cycle in healthy women Pain 146 2009 47 55
192. Y. Tousignant-Laflamme, S. Page, P. Goffaux, and S. Marchand An experimental model to measure excitatory and inhibitory pain mechanisms in humans Brain Res 1230 2008 73 79
193. Y. Tousignant-Laflamme, P. Rainville, and S. Marchand Establishing a link between heart rate and pain in healthy subjects: a gender effect J Pain 6 2005 341 347 (Pubitemid 40804338)
194. A.M. Unruh Gender variations in clinical pain experience Pain 65 1996 123 167 (Pubitemid 26228032)
195. A.H. Vallerand, and R.C. Polomano The relationship of gender to pain Pain Manag Nurs 1 2000 8 15
196. L. Villanueva, S.W. Cadden, and D. Le Bars Evidence that diffuse noxious inhibitory controls (DNIC) are medicated by a final post-synaptic inhibitory mechanism Brain Res 298 1984 67 74 (Pubitemid 14135604)
197. L. Villanueva, and D. Le Bars The activation of bulbo-spinal controls by peripheral nociceptive inputs: diffuse noxious inhibitory controls Biol Res 28 1995 113 125
198. C.S. Weisse, K.K. Foster, and E.A. Fisher The influence of experimenter gender and race on pain reporting: does racial or gender concordance matter? Pain Med 6 2005 80 87 (Pubitemid 40361226)
199. I. Weissman-Fogel, E. Sprecher, and D. Pud Effects of catastrophizing on pain perception and pain modulation Exp Brain Res 186 2008 79 85
200. Z. Wiesenfeld-Hallin Sex differences in pain perception Gend Med 2 2005 137 145 (Pubitemid 41700276)
201. E.A. Wise, D.D. Price, C.D. Myers, M.W. Heft, and M.E. Robinson Gender role expectations of pain: relationship to experimental pain perception Pain 96 2002 335 342 (Pubitemid 34327881)
202. M.T. Wizemann, and M.-L. Pardue Exploring the biological contributions to human health: does sex matter? 2001 National Academy Press Washington, DC
203. K. Yamada, and T. Nabeshima Stress-induced behavioral responses and multiple opioid systems in the brain Behav Brain Res 67 1995 133 145
204. D. Yarnitsky, L. Arendt-Nielsen, D. Bouhassira, R.R. Edwards, R.B. Fillingim, M. Granot, P. Hansson, S. Lautenbacher, S. Marchand, and O. Wilder-Smith Recommendations on terminology and practice of psychophysical DNIC testing Eur J Pain 14 2010 339
205. N. Zamir, and W. Maixner The relationship between cardiovascular and pain regulatory systems Ann N Y Acad Sci 467 1986 371 384 (Pubitemid 16029638)
206. A. Zeichner, M. Loftin, G. Panopoulos, S. Widner, and J. Allen Sex differences in pain indices, exercise, and use of analgesics Psychol Rep 86 2000 129 133
207. C. Zimmer, H.D. Basler, H. Vedder, and S. Lautenbacher Sex differences in cortisol response to noxious stress Clin J Pain 19 2003 233 239 (Pubitemid 36828737)
208. J.K. Zubieta, Y.R. Smith, J.A. Bueller, Y. Xu, M.R. Kilbourn, D.M. Jewett, C.R. Meyer, R.A. Koeppe, and C.S. Stohler Mu-opioid receptor-mediated antinociceptive responses differ in men and women J Neurosci 22 2002 5100 5107 (Pubitemid 37465623)