Mechanistic approach for the development of vultrafine oil-water emulsions using monoglyceride and blends of medium and long chain triglycerides: Enhancement of the solubility and bioavailability of Perphenazine

Journal of Excipients and Food Chemicals

Volumn 4, Issue 1, 2013, Pages 12-24

  Baboota, Sanjula ^a   Abdullah, A ^a   Mustafa, Gulam ^a   Sahni, Jasjeet Kaur ^a   Ali, Javed ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Nanoemulsion; Perphenazine; Pharmacokinetic; Phase diagram

Indexed keywords

CARBOMER; CARBOXYMETHYLCELLULOSE; DIETHYLENE GLYCOL MONOETHYL ETHER; LINSEED OIL; LONG CHAIN TRIACYLGLYCEROL; MACROGOL 200; MACROGOL 400; MEDIUM CHAIN TRIACYLGLYCEROL; MONOACYLGLYCEROL; MONOCAPRYLIC ACID PROPYLENE GLYCOL ESTER; PERPHENAZINE; POLYSORBATE 20; POLYSORBATE 40; POLYSORBATE 80; STABILIZING AGENT; TRIACETIN; UNCLASSIFIED DRUG; WATER; WATER OIL CREAM;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DISTRIBUTION; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG PENETRATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STRUCTURE; EMULSION; EX VIVO STUDY; GASTROINTESTINAL TRACT; INTESTINE MUCOSA; LIMIT OF DETECTION; LIMIT OF QUANTITATION; MAXIMUM PLASMA CONCENTRATION; NANOEMULSION; NONHUMAN; PARTICLE SIZE; QUANTITATIVE ANALYSIS; RAT; REFRACTION INDEX; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SPECTROSCOPY; SURFACE PROPERTY; TIME TO MAXIMUM PLASMA CONCENTRATION; TITRIMETRY; VISCOSITY;

RATTUS; RATTUS NORVEGICUS;

EID: 84875926107     PISSN: None     EISSN: 21502668     Source Type: Journal    
DOI: None     Document Type: Article

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