Fast-dissolving sublingual solid dispersion and cyclodextrin complex increase the absorption of perphenazine in rabbits

Journal of Pharmacy and Pharmacology

Volumn 63, Issue 1, 2011, Pages 19-25

  Turunen, Elina ^a   Mannila, Janne ^a   Laitinen, Riikka ^a   Riikonen, Joakim ^a,b   Lehto, Vesa Pekka ^a   Järvinena, Tomi ^a   Ketolainen, Jarkko ^a   Järvinenc, Kristiina ^a   Jarho, Pekka ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

Author keywords

absorption; cyclodextrin complex; solid dispersion; sublingual administration

Indexed keywords

BETA CYCLODEXTRIN; MACROGOL 8000; PERPHENAZINE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; COMPLEX FORMATION; DISPERSION; DRUG ABSORPTION; DRUG FORMULATION; DRUG METABOLISM; DRUG SOLUBILITY; FREEZE DRYING; MALE; NONHUMAN; RABBIT; SPRAY DRYING;

ADMINISTRATION, ORAL; ANIMALS; ANTIPSYCHOTIC AGENTS; AREA UNDER CURVE; BETA-CYCLODEXTRINS; EXCIPIENTS; FREEZE DRYING; MALE; PARTICLE SIZE; PERPHENAZINE; POLYETHYLENE GLYCOLS; RABBITS; SOLUBILITY;

EID: 78650371506     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2010.01173.x     Document Type: Article

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