-
1
-
-
0028934541
-
REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons
-
Chong JA, Tapia-Ramirez J, Kim S, Toledo-Aral JJ, Zheng Y, Boutros MC et al. REST: A mammalian silencer protein that restricts sodium channel gene expression to neurons. Cell 1995; 80: 949-957.
-
(1995)
Cell
, vol.80
, pp. 949-957
-
-
Chong, J.A.1
Tapia-Ramirez, J.2
Kim, S.3
Toledo-Aral, J.J.4
Zheng, Y.5
Boutros, M.C.6
-
2
-
-
0028968802
-
The neuron-restrictive silencer factor (NRSF): A coordinate repressor of multiple neuron-specific genes
-
Schoenherr CJ, Anderson DJ. The neuron-restrictive silencer factor (NRSF): A coordinate repressor of multiple neuron-specific genes. Science 1995; 267: 1360-1363.
-
(1995)
Science
, vol.267
, pp. 1360-1363
-
-
Schoenherr, C.J.1
Anderson, D.J.2
-
3
-
-
19344378337
-
REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis
-
Ballas N, Grunseich C, Lu DD, Speh JC, Mandel G. REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell 2005; 121: 645-657.
-
(2005)
Cell
, vol.121
, pp. 645-657
-
-
Ballas, N.1
Grunseich, C.2
Lu, D.D.3
Speh, J.C.4
Mandel, G.5
-
4
-
-
25844518743
-
The many faces of REST oversee epigenetic programming of neuronal genes
-
Ballas N, Mandel G. The many faces of REST oversee epigenetic programming of neuronal genes. Curr Opin Neurobiol 2005; 15: 500-506.
-
(2005)
Curr Opin Neurobiol
, vol.15
, pp. 500-506
-
-
Ballas, N.1
Mandel, G.2
-
5
-
-
27544454705
-
Chromatin remodeling in neural development and plasticity
-
Hsieh J, Gage FH. Chromatin remodeling in neural development and plasticity. Curr Opin Cell Biol 2005; 17: 664-671.
-
(2005)
Curr Opin Cell Biol
, vol.17
, pp. 664-671
-
-
Hsieh, J.1
Gage, F.H.2
-
6
-
-
34250767817
-
Chromatin crosstalk in development and disease: Lessons from REST
-
Ooi L, Wood IC. Chromatin crosstalk in development and disease: Lessons from REST. Nat Rev Genet 2007; 8: 544-554.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 544-554
-
-
Ooi, L.1
Wood, I.C.2
-
8
-
-
77954041258
-
REST and CoREST modulate neuronal subtype specification, maturation and maintenance
-
Abrajano JJ, Qureshi IA, Gokhan S, Zheng D, Bergman A, Mehler MF. REST and CoREST modulate neuronal subtype specification, maturation and maintenance. PLoS One 2009; 4: E7936.
-
(2009)
PLoS One
, vol.4
-
-
Abrajano, J.J.1
Qureshi, I.A.2
Gokhan, S.3
Zheng, D.4
Bergman, A.5
Mehler, M.F.6
-
9
-
-
77956405805
-
Chromatin remodeling in neural stem cell differentiation
-
Juliandi B, Abematsu M, Nakashima K. Chromatin remodeling in neural stem cell differentiation. Curr Opin Neurobiol 2010; 20: 408-415.
-
(2010)
Curr Opin Neurobiol
, vol.20
, pp. 408-415
-
-
Juliandi, B.1
Abematsu, M.2
Nakashima, K.3
-
10
-
-
67149121885
-
REST and the RESTless: In stem cells and beyond
-
Gopalakrishnan V. REST and the RESTless: In stem cells and beyond. Future Neurol 2009; 4: 317-329.
-
(2009)
Future Neurol
, vol.4
, pp. 317-329
-
-
Gopalakrishnan, V.1
-
11
-
-
79960007644
-
The master negative regulator REST/NRSF controls adult neurogenesis by restraining the neurogenic program in quiescent stem cells
-
Gao Z, Ure K, Ding P, Nashaat M, Yuan L, Ma J et al. The master negative regulator REST/NRSF controls adult neurogenesis by restraining the neurogenic program in quiescent stem cells. J Neurosci 2011; 31: 9772-9786.
-
(2011)
J Neurosci
, vol.31
, pp. 9772-9786
-
-
Gao, Z.1
Ure, K.2
Ding, P.3
Nashaat, M.4
Yuan, L.5
Ma, J.6
-
12
-
-
0033942317
-
The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells
-
Lawinger P, Venugopal R, Guo ZS, Immaneni A, Sengupta D, Lu W et al. The neuronal repressor REST/NRSF is an essential regulator in medulloblastoma cells. Nat Med 2000; 6: 826-831.
-
(2000)
Nat Med
, vol.6
, pp. 826-831
-
-
Lawinger, P.1
Venugopal, R.2
Guo, Z.S.3
Immaneni, A.4
Sengupta, D.5
Lu, W.6
-
13
-
-
33644518372
-
Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation
-
Su X, Gopalakrishnan V, Stearns D, Aldape K, Lang FF, Fuller G et al. Abnormal expression of REST/NRSF and Myc in neural stem/progenitor cells causes cerebellar tumors by blocking neuronal differentiation. Mol Cell Biol 2006; 26: 1666-1678.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 1666-1678
-
-
Su, X.1
Gopalakrishnan, V.2
Stearns, D.3
Aldape, K.4
Lang, F.F.5
Fuller, G.6
-
14
-
-
15944374306
-
Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16
-
Fuller GN, Su X, Price RE, Cohen ZR, Lang FF, Sawaya R et al. Many human medulloblastoma tumors overexpress repressor element-1 silencing transcription (REST)/neuron-restrictive silencer factor, which can be functionally countered by REST-VP16. Mol Cancer Ther 2005; 4: 343-349.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 343-349
-
-
Fuller, G.N.1
Su, X.2
Price, R.E.3
Cohen, Z.R.4
Lang, F.F.5
Sawaya, R.6
-
15
-
-
0034255133
-
A role for p27/Kip1 in the control of cerebellar granule cell precursor proliferation
-
Miyazawa K, Himi T, Garcia V, Yamagishi H, Sato S, Ishizaki Y. A role for p27/Kip1 in the control of cerebellar granule cell precursor proliferation. J Neurosci 2000; 20: 5756-5763.
-
(2000)
J Neurosci
, vol.20
, pp. 5756-5763
-
-
Miyazawa, K.1
Himi, T.2
Garcia, V.3
Yamagishi, H.4
Sato, S.5
Ishizaki, Y.6
-
16
-
-
17444369004
-
Altered patterns of neuron production in the p27 knockout mouse
-
Goto T, Mitsuhashi T, Takahashi T. Altered patterns of neuron production in the p27 knockout mouse. Dev Neurosci 2004; 26: 208-217.
-
(2004)
Dev Neurosci
, vol.26
, pp. 208-217
-
-
Goto, T.1
Mitsuhashi, T.2
Takahashi, T.3
-
17
-
-
33746847816
-
N-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and p27Kip1 coordinately regulate cerebellar development
-
Zindy F, Knoepfler PS, Xie S, Sherr CJ, Eisenman RN, Roussel MF. N-Myc and the cyclin-dependent kinase inhibitors p18Ink4c and p27Kip1 coordinately regulate cerebellar development. Proc Natl Acad Sci USA 2006; 103: 11579-11583.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 11579-11583
-
-
Zindy, F.1
Knoepfler, P.S.2
Xie, S.3
Sherr, C.J.4
Eisenman, R.N.5
Roussel, M.F.6
-
18
-
-
70349733115
-
Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: Separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization
-
Bhatia B, Northcott PA, Hambardzumyan D, Govindarajan B, Brat DJ, Arbiser JL et al. Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: Separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization. Cancer Res 2009; 69: 7224-7234.
-
(2009)
Cancer Res
, vol.69
, pp. 7224-7234
-
-
Bhatia, B.1
Northcott, P.A.2
Hambardzumyan, D.3
Govindarajan, B.4
Brat, D.J.5
Arbiser, J.L.6
-
19
-
-
77958515887
-
P27(Kip1), a double-edged sword in Shh-mediated medulloblastoma: Tumor accelerator and suppressor
-
Bhatia B, Malik A, Fernandez LA, Kenney AM. p27(Kip1), a double-edged sword in Shh-mediated medulloblastoma: Tumor accelerator and suppressor. Cell Cycle 2010; 9: 4307-4314.
-
(2010)
Cell Cycle
, vol.9
, pp. 4307-4314
-
-
Bhatia, B.1
Malik, A.2
Fernandez, L.A.3
Kenney, A.M.4
-
20
-
-
77951898362
-
Double trouble: When sonic hedgehog signaling meets TSC inactivation
-
Bhatia B, Nahle Z, Kenney AM. Double trouble: When sonic hedgehog signaling meets TSC inactivation. Cell Cycle 2010; 9: 456-459.
-
(2010)
Cell Cycle
, vol.9
, pp. 456-459
-
-
Bhatia, B.1
Nahle, Z.2
Kenney, A.M.3
-
21
-
-
58649120079
-
Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma
-
Ayrault O, Zindy F, Rehg J, Sherr CJ, Roussel MF. Two tumor suppressors, p27Kip1 and patched-1, collaborate to prevent medulloblastoma. Mol Cancer Res 2009; 7: 33-40.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 33-40
-
-
Ayrault, O.1
Zindy, F.2
Rehg, J.3
Sherr, C.J.4
Roussel, M.F.5
-
22
-
-
79959906646
-
Balancing act: Deubiquitinating enzymes in the nervous system
-
Todi SV, Paulson HL. Balancing act: Deubiquitinating enzymes in the nervous system. Trends Neurosci 2011.
-
(2011)
Trends Neurosci
-
-
Todi, S.V.1
Paulson, H.L.2
-
23
-
-
67650620318
-
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes
-
Reyes-Turcu FE, Ventii KH, Wilkinson KD. Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes. Annu Rev Biochem 2009; 78: 363-397.
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 363-397
-
-
Reyes-Turcu, F.E.1
Ventii, K.H.2
Wilkinson, K.D.3
-
24
-
-
67649634849
-
Defining the human deubiquitinating enzyme interaction landscape
-
Sowa ME, Bennett EJ, Gygi SP, Harper JW. Defining the human deubiquitinating enzyme interaction landscape. Cell 2009; 138: 389-403.
-
(2009)
Cell
, vol.138
, pp. 389-403
-
-
Sowa, M.E.1
Bennett, E.J.2
Gygi, S.P.3
Harper, J.W.4
-
25
-
-
33749024194
-
N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth
-
Hatton BA, Knoepfler PS, Kenney AM, Rowitch DH, de Alboran IM, Olson JM et al. N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth. Cancer Res 2006; 66: 8655-8661.
-
(2006)
Cancer Res
, vol.66
, pp. 8655-8661
-
-
Hatton, B.A.1
Knoepfler, P.S.2
Kenney, A.M.3
Rowitch, D.H.4
De Alboran, I.M.5
Olson, J.M.6
-
26
-
-
0037108268
-
N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation
-
Knoepfler PS, Cheng PF, Eisenman RN. N-myc is essential during neurogenesis for the rapid expansion of progenitor cell populations and the inhibition of neuronal differentiation. Genes Dev 2002; 16: 2699-2712.
-
(2002)
Genes Dev
, vol.16
, pp. 2699-2712
-
-
Knoepfler, P.S.1
Cheng, P.F.2
Eisenman, R.N.3
-
27
-
-
0037325853
-
Deregulated degradation of the cdk inhibitor p27 and malignant transformation
-
Bloom J, Pagano M. Deregulated degradation of the cdk inhibitor p27 and malignant transformation. Semin Cancer Biol 2003; 13: 41-47.
-
(2003)
Semin Cancer Biol
, vol.13
, pp. 41-47
-
-
Bloom, J.1
Pagano, M.2
-
28
-
-
0033176887
-
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
-
Carrano AC, Eytan E, Hershko A, Pagano M. SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nat Cell Biol 1999; 1: 193-199.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 193-199
-
-
Carrano, A.C.1
Eytan, E.2
Hershko, A.3
Pagano, M.4
-
29
-
-
47149092405
-
Targeting the p27 E3 ligase SCF(Skp2) results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy
-
Chen Q, Xie W, Kuhn DJ, Voorhees PM, Lopez-Girona A, Mendy D et al. Targeting the p27 E3 ligase SCF(Skp2) results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy. Blood 2008; 111: 4690-4699.
-
(2008)
Blood
, vol.111
, pp. 4690-4699
-
-
Chen, Q.1
Xie, W.2
Kuhn, D.J.3
Voorhees, P.M.4
Lopez-Girona, A.5
Mendy, D.6
-
30
-
-
44349122993
-
Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: Tipping the scales of cancer
-
Frescas D, Pagano M. Deregulated proteolysis by the F-box proteins SKP2 and beta-TrCP: Tipping the scales of cancer. Nat Rev Cancer 2008; 8: 438-449.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 438-449
-
-
Frescas, D.1
Pagano, M.2
-
31
-
-
27144534830
-
Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle
-
Hara T, Kamura T, Kotoshiba S, Takahashi H, Fujiwara K, Onoyama I et al. Role of the UBL-UBA protein KPC2 in degradation of p27 at G1 phase of the cell cycle. Mol Cell Biol 2005; 25: 9292-9303.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 9292-9303
-
-
Hara, T.1
Kamura, T.2
Kotoshiba, S.3
Takahashi, H.4
Fujiwara, K.5
Onoyama, I.6
-
32
-
-
10344260649
-
Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase
-
Kamura T, Hara T, Matsumoto M, Ishida N, Okumura F, Hatakeyama S et al. Cytoplasmic ubiquitin ligase KPC regulates proteolysis of p27(Kip1) at G1 phase. Nat Cell Biol 2004; 6: 1229-1235.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1229-1235
-
-
Kamura, T.1
Hara, T.2
Matsumoto, M.3
Ishida, N.4
Okumura, F.5
Hatakeyama, S.6
-
33
-
-
34249097128
-
Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis
-
Keller UB, Old JB, Dorsey FC, Nilsson JA, Nilsson L, MacLean KH et al. Myc targets Cks1 to provoke the suppression of p27Kip1, proliferation and lymphomagenesis. EMBO J 2007; 26: 2562-2574.
-
(2007)
EMBO J
, vol.26
, pp. 2562-2574
-
-
Keller, U.B.1
Old, J.B.2
Dorsey, F.C.3
Nilsson, J.A.4
Nilsson, L.5
MacLean, K.H.6
-
34
-
-
24044555556
-
Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase
-
Kotoshiba S, Kamura T, Hara T, Ishida N, Nakayama KI. Molecular dissection of the interaction between p27 and Kip1 ubiquitylation-promoting complex, the ubiquitin ligase that regulates proteolysis of p27 in G1 phase. J Biol Chem 2005; 280: 17694-17700.
-
(2005)
J Biol Chem
, vol.280
, pp. 17694-17700
-
-
Kotoshiba, S.1
Kamura, T.2
Hara, T.3
Ishida, N.4
Nakayama, K.I.5
-
35
-
-
77954152739
-
Ubiquitylation and proteasomal degradation of the p21(Cip1) p27(Kip1) and p57(Kip2) CDK inhibitors
-
Lu Z, Hunter T. Ubiquitylation and proteasomal degradation of the p21(Cip1), p27(Kip1) and p57(Kip2) CDK inhibitors. Cell Cycle 2010; 9: 2400-2411.
-
(2010)
Cell Cycle
, vol.9
, pp. 2400-2411
-
-
Lu, Z.1
Hunter, T.2
-
36
-
-
24044471278
-
Ubiquitination of p27Kip1 requires physical interaction with cyclin E and probable phosphate recognition by SKP2
-
Ungermannova D, Gao Y, Liu X. Ubiquitination of p27Kip1 requires physical interaction with cyclin E and probable phosphate recognition by SKP2. J Biol Chem 2005; 280: 30301-30309.
-
(2005)
J Biol Chem
, vol.280
, pp. 30301-30309
-
-
Ungermannova, D.1
Gao, Y.2
Liu, X.3
-
37
-
-
77950090066
-
Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts
-
Masuda K, Ishikawa Y, Onoyama I, Unno M, de Alboran IM, Nakayama KI et al. Complex regulation of cell-cycle inhibitors by Fbxw7 in mouse embryonic fibroblasts. Oncogene 2010; 29: 1798-1809.
-
(2010)
Oncogene
, vol.29
, pp. 1798-1809
-
-
Masuda, K.1
Ishikawa, Y.2
Onoyama, I.3
Unno, M.4
De Alboran, I.M.5
Nakayama, K.I.6
-
38
-
-
69649103904
-
DUBs at a glance
-
Wilkinson KD. DUBs at a glance. J Cell Sci 2009; 122(Part 14): 2325-2329.
-
(2009)
J Cell Sci
, vol.122
, Issue.PART14
, pp. 2325-2329
-
-
Wilkinson, K.D.1
-
39
-
-
68049084674
-
Breaking the chains: Structure and function of the deubiquitinases
-
Komander D, Clague MJ, Urbe S. Breaking the chains: Structure and function of the deubiquitinases. Nat Rev Mol Cell Biol 2009; 10: 550-563.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbe, S.3
-
40
-
-
3142764484
-
Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes
-
Bruce AW, Donaldson IJ, Wood IC, Yerbury SA, Sadowski MI, Chapman M et al. Genome-wide analysis of repressor element 1 silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) target genes. Proc Natl Acad Sci USA 2004; 101: 10458-10463.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 10458-10463
-
-
Bruce, A.W.1
Donaldson, I.J.2
Wood, I.C.3
Yerbury, S.A.4
Sadowski, M.I.5
Chapman, M.6
-
41
-
-
56349138235
-
Rest-mediated regulation of extracellular matrix is crucial for neural development
-
Sun YM, Cooper M, Finch S, Lin HH, Chen ZF, Williams BP et al. Rest-mediated regulation of extracellular matrix is crucial for neural development. PLoS One 2008; 3: E3656.
-
(2008)
PLoS One
, vol.3
-
-
Sun, Y.M.1
Cooper, M.2
Finch, S.3
Lin, H.H.4
Chen, Z.F.5
Williams, B.P.6
-
42
-
-
41149130221
-
Control of chromosome stability by the beta-TrCP-REST-Mad2 axis
-
Guardavaccaro D, Frescas D, Dorrello NV, Peschiaroli A, Multani AS, Cardozo T et al. Control of chromosome stability by the beta-TrCP-REST-Mad2 axis. Nature 2008; 452: 365-369.
-
(2008)
Nature
, vol.452
, pp. 365-369
-
-
Guardavaccaro, D.1
Frescas, D.2
Dorrello, N.V.3
Peschiaroli, A.4
Multani, A.S.5
Cardozo, T.6
-
43
-
-
79954459885
-
Expression regulation of the metastasis-promoting protein InsP3-kinase-A in tumor cells
-
Chang L, Schwarzenbach H, Meyer-Staeckling S, Brandt B, Mayr GW, Weitzel JM et al. Expression regulation of the metastasis-promoting protein InsP3-kinase-A in tumor cells. Mol Cancer Res 2011.
-
(2011)
Mol Cancer Res
-
-
Chang, L.1
Schwarzenbach, H.2
Meyer-Staeckling, S.3
Brandt, B.4
Mayr, G.W.5
Weitzel, J.M.6
-
44
-
-
70449578270
-
Differential deployment of REST and CoREST promotes glial subtype specification and oligodendrocyte lineage maturation
-
Abrajano JJ, Qureshi IA, Gokhan S, Zheng D, Bergman A, Mehler MF. Differential deployment of REST and CoREST promotes glial subtype specification and oligodendrocyte lineage maturation. PLoS One 2009; 4: E7665.
-
(2009)
PLoS One
, vol.4
-
-
Abrajano, J.J.1
Qureshi, I.A.2
Gokhan, S.3
Zheng, D.4
Bergman, A.5
Mehler, M.F.6
-
45
-
-
77950583698
-
BMP-induced REST regulates the establishment and maintenance of astrocytic identity
-
Kohyama J, Sanosaka T, Tokunaga A, Takatsuka E, Tsujimura K, Okano H et al. BMP-induced REST regulates the establishment and maintenance of astrocytic identity. J Cell Biol 2010; 189: 159-170.
-
(2010)
J Cell Biol
, vol.189
, pp. 159-170
-
-
Kohyama, J.1
Sanosaka, T.2
Tokunaga, A.3
Takatsuka, E.4
Tsujimura, K.5
Okano, H.6
-
46
-
-
77952550259
-
Transcriptional inhibition of REST by NeuroD2 during neuronal differentiation
-
Ravanpay AC, Hansen SJ, Olson JM. Transcriptional inhibition of REST by NeuroD2 during neuronal differentiation. Mol Cell Neurosci 2010; 44: 178-189.
-
(2010)
Mol Cell Neurosci
, vol.44
, pp. 178-189
-
-
Ravanpay, A.C.1
Hansen, S.J.2
Olson, J.M.3
-
47
-
-
80054011480
-
A signaling loop of REST, TSC2 and {beta}-catenin governs proliferation and function of PC12 neural cells
-
Tomasoni R, Negrini S, Fiordaliso S, Klajn A, Tkatch T, Mondino A et al. A signaling loop of REST, TSC2 and {beta}-catenin governs proliferation and function of PC12 neural cells. J Cell Sci 2011; 124(Pt 18): 3174-3186.
-
(2011)
J Cell Sci
, vol.124
, Issue.PART18
, pp. 3174-3186
-
-
Tomasoni, R.1
Negrini, S.2
Fiordaliso, S.3
Klajn, A.4
Tkatch, T.5
Mondino, A.6
-
48
-
-
78751505998
-
P27: A barometer of signaling deregulation and potential predictor of response to targeted therapies
-
Wander SA, Zhao D, Slingerland JM. p27: A barometer of signaling deregulation and potential predictor of response to targeted therapies. Clin Cancer Res 2011; 17: 12-18.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 12-18
-
-
Wander, S.A.1
Zhao, D.2
Slingerland, J.M.3
-
49
-
-
60749109846
-
Cell cycle CDKs and cancer: A changing paradigm
-
Malumbres M, Barbacid M. Cell cycle, CDKs and cancer: A changing paradigm. Nat Rev Cancer 2009; 9: 153-166.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 153-166
-
-
Malumbres, M.1
Barbacid, M.2
-
50
-
-
71049169616
-
Cyclin-dependent kinases: A family portrait
-
Malumbres M, Harlow E, Hunt T, Hunter T, Lahti JM, Manning G et al. Cyclin-dependent kinases: A family portrait. Nat Cell Biol 2009; 11: 1275-1276.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1275-1276
-
-
Malumbres, M.1
Harlow, E.2
Hunt, T.3
Hunter, T.4
Lahti, J.M.5
Manning, G.6
-
51
-
-
42449087261
-
Switching cyclin D-Cdk4 kinase activity on and off
-
Blain SW. Switching cyclin D-Cdk4 kinase activity on and off. Cell Cycle 2008; 7: 892-898.
-
(2008)
Cell Cycle
, vol.7
, pp. 892-898
-
-
Blain, S.W.1
-
52
-
-
41149150219
-
The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy
-
Chu IM, Hengst L, Slingerland JM. The Cdk inhibitor p27 in human cancer: Prognostic potential and relevance to anticancer therapy. Nat Rev Cancer 2008; 8: 253-267.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 253-267
-
-
Chu, I.M.1
Hengst, L.2
Slingerland, J.M.3
-
53
-
-
33846330967
-
Another piece of the p27Kip1 puzzle
-
Kaldis P. Another piece of the p27Kip1 puzzle. Cell 2007; 128: 241-244.
-
(2007)
Cell
, vol.128
, pp. 241-244
-
-
Kaldis, P.1
-
54
-
-
2442515980
-
Control of DNA synthesis and mitosis by the Skp2-p27-Cdk1/2 axis
-
Pagano M. Control of DNA synthesis and mitosis by the Skp2-p27-Cdk1/2 axis. Mol Cell 2004; 14: 414-416.
-
(2004)
Mol Cell
, vol.14
, pp. 414-416
-
-
Pagano, M.1
-
55
-
-
0041696635
-
Keeping p27(Kip1) in the cytoplasm: A second front in cancer's war on p27
-
Reed SI. Keeping p27(Kip1) in the cytoplasm: A second front in cancer's war on p27. Cell Cycle 2002; 1: 389-390.
-
(2002)
Cell Cycle
, vol.1
, pp. 389-390
-
-
Reed, S.I.1
-
56
-
-
32044441426
-
How to decrease p27Kip1 levels during tumor development
-
Koff A. How to decrease p27Kip1 levels during tumor development. Cancer Cell 2006; 9: 75-76.
-
(2006)
Cancer Cell
, vol.9
, pp. 75-76
-
-
Koff, A.1
-
57
-
-
79955977893
-
Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry
-
Huang X, Summers MK, Pham V, Lill JR, Liu J, Lee G et al. Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry. Mol Cell 2011; 42: 511-523.
-
(2011)
Mol Cell
, vol.42
, pp. 511-523
-
-
Huang, X.1
Summers, M.K.2
Pham, V.3
Lill, J.R.4
Liu, J.5
Lee, G.6
-
58
-
-
41149119961
-
SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation
-
Westbrook TF, Hu G, Ang XL, Mulligan P, Pavlova NN, Liang A et al. SCFbeta-TRCP controls oncogenic transformation and neural differentiation through REST degradation. Nature 2008; 452: 370-374.
-
(2008)
Nature
, vol.452
, pp. 370-374
-
-
Westbrook, T.F.1
Hu, G.2
Ang, X.L.3
Mulligan, P.4
Pavlova, N.N.5
Liang, A.6
-
59
-
-
20444376939
-
A genetic screen for candidate tumor suppressors identifies REST
-
Westbrook TF, Martin ES, Schlabach MR, Leng Y, Liang AC, Feng B et al. A genetic screen for candidate tumor suppressors identifies REST. Cell. 2005; 121: 837-848.
-
(2005)
Cell.
, vol.121
, pp. 837-848
-
-
Westbrook, T.F.1
Martin, E.S.2
Schlabach, M.R.3
Leng, Y.4
Liang, A.C.5
Feng, B.6
-
60
-
-
33748937903
-
Regulation and role of REST and REST4 variants in modulation of gene expression in in vivo and in vitro in epilepsy models
-
Spencer EM, Chandler KE, Haddley K, Howard MR, Hughes D, Belyaev ND et al. Regulation and role of REST and REST4 variants in modulation of gene expression in in vivo and in vitro in epilepsy models. Neurobiol Dis 2006; 24: 41-52.
-
(2006)
Neurobiol Dis
, vol.24
, pp. 41-52
-
-
Spencer, E.M.1
Chandler, K.E.2
Haddley, K.3
Howard, M.R.4
Hughes, D.5
Belyaev, N.D.6
-
61
-
-
24044505984
-
Transcriptional regulation: Cancer, neurons and the rest
-
Coulson JM. Transcriptional regulation: Cancer, neurons and the REST. Curr Biol 2005; 15: R665-R668.
-
(2005)
Curr Biol
, vol.15
-
-
Coulson, J.M.1
-
62
-
-
77950517895
-
Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A
-
Pereg Y, Liu BY, O'Rourke KM, Sagolla M, Dey A, Komuves L et al. Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A. Nat Cell Biol 2010; 12: 400-406.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 400-406
-
-
Pereg, Y.1
Liu, B.Y.2
O'Rourke, K.M.3
Sagolla, M.4
Dey, A.5
Komuves, L.6
-
63
-
-
23044506681
-
The ubiquitin-proteasome pathway and its role in cancer
-
Mani A, Gelmann EP. The ubiquitin-proteasome pathway and its role in cancer. J Clin Oncol 2005; 23: 4776-4789.
-
(2005)
J Clin Oncol
, vol.23
, pp. 4776-4789
-
-
Mani, A.1
Gelmann, E.P.2
-
64
-
-
34547421345
-
The tumor suppressor CYLD regulates entry into mitosis
-
Stegmeier F, Sowa ME, Nalepa G, Gygi SP, Harper JW, Elledge SJ. The tumor suppressor CYLD regulates entry into mitosis. Proc Natl Acad Sci USA 2007; 104: 8869-8874.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 8869-8874
-
-
Stegmeier, F.1
Sowa, M.E.2
Nalepa, G.3
Gygi, S.P.4
Harper, J.W.5
Elledge, S.J.6
-
65
-
-
77949265991
-
The ubiquitin-specific protease USP47 is a novel beta-TRCP interactor regulating cell survival
-
Peschiaroli A, Skaar JR, Pagano M, Melino G. The ubiquitin-specific protease USP47 is a novel beta-TRCP interactor regulating cell survival. Oncogene 2010; 29: 1384-1393.
-
(2010)
Oncogene
, vol.29
, pp. 1384-1393
-
-
Peschiaroli, A.1
Skaar, J.R.2
Pagano, M.3
Melino, G.4
-
66
-
-
77951048024
-
The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression
-
McFarlane C, Kelvin AA, de la Vega M, Govender U, Scott CJ, Burrows JF et al. The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression. Cancer Res 2010; 70: 3329-3339.
-
(2010)
Cancer Res
, vol.70
, pp. 3329-3339
-
-
McFarlane, C.1
Kelvin, A.A.2
De La Vega, M.3
Govender, U.4
Scott, C.J.5
Burrows, J.F.6
-
67
-
-
50849116784
-
Usp39 is essential for mitotic spindle checkpoint integrity and controls mRNA-levels of aurora B
-
van Leuken RJ, Luna-Vargas MP, Sixma TK, Wolthuis RM, Medema RH. Usp39 is essential for mitotic spindle checkpoint integrity and controls mRNA-levels of aurora B. Cell Cycle 2008; 7: 2710-2719.
-
(2008)
Cell Cycle
, vol.7
, pp. 2710-2719
-
-
Van Leuken, R.J.1
Luna-Vargas, M.P.2
Sixma, T.K.3
Wolthuis, R.M.4
Medema, R.H.5
-
68
-
-
79955934205
-
An emerging model for BAP1's role in regulating cell cycle progression
-
Eletr ZM, Wilkinson KD. An emerging model for BAP1's role in regulating cell cycle progression. Cell Biochem Biophys 2011; 60: 3-11.
-
(2011)
Cell Biochem Biophys
, vol.60
, pp. 3-11
-
-
Eletr, Z.M.1
Wilkinson, K.D.2
-
69
-
-
77950518762
-
Cdc25A Harper JW and Dub3 in a high-stakes balancing act
-
Hayes SD, Cdc25A Harper JW. and Dub3 in a high-stakes balancing act. Nat Cell Biol 2010; 12: 311-313.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 311-313
-
-
Hayes, S.D.1
-
70
-
-
67349128584
-
Reactivation of death receptor 4 (DR4) expression sensitizes medulloblastoma cell lines to TRAIL
-
Aguilera DG, Das CM, Sinnappah-Kang ND, Joyce C, Taylor PH, Wen S et al. Reactivation of death receptor 4 (DR4) expression sensitizes medulloblastoma cell lines to TRAIL. J Neurooncol 2009; 93: 303-318.
-
(2009)
J Neurooncol
, vol.93
, pp. 303-318
-
-
Aguilera, D.G.1
Das, C.M.2
Sinnappah-Kang, N.D.3
Joyce, C.4
Taylor, P.H.5
Wen, S.6
-
71
-
-
80555155590
-
Retinoic acid induces REST degradation and neuronal differentiation by modulating the expression of SCF(beta-TRCP) in neuroblastoma cells
-
Singh A, Rokes C, Gireud M, Fletcher S, Baumgartner J, Fuller G et al. Retinoic acid induces REST degradation and neuronal differentiation by modulating the expression of SCF(beta-TRCP) in neuroblastoma cells. Cancer 2011; 117: 5189-5202.
-
(2011)
Cancer
, vol.117
, pp. 5189-5202
-
-
Singh, A.1
Rokes, C.2
Gireud, M.3
Fletcher, S.4
Baumgartner, J.5
Fuller, G.6
-
72
-
-
77957196094
-
Chromatin remodelling at the topoisomerase II-beta promoter is associated with enhanced sensitivity to etoposide in human neuroblastoma cell lines
-
Das CM, Zage PE, Taylor P, Aguilera D, Wolff JE, Lee D et al. Chromatin remodelling at the topoisomerase II-beta promoter is associated with enhanced sensitivity to etoposide in human neuroblastoma cell lines. Eur J Cancer 2010; 46: 2771-2780.
-
(2010)
Eur J Cancer
, vol.46
, pp. 2771-2780
-
-
Das, C.M.1
Zage, P.E.2
Taylor, P.3
Aguilera, D.4
Wolff, J.E.5
Lee, D.6
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