Induced mutant mice expressing lipoprotein lipase exclusively in muscle have subnormal triglycerides yet reduced high density lipoprotein cholesterol levels in plasma

Journal of Biological Chemistry

Volumn 272, Issue 27, 1997, Pages 17182-17190

  Levak Frank, Sanja ^a   Weinstock, Peter H ^b   Hayek, Tony ^b   Verdery, Roy ^c   Hofmann, Wolfgang ^a   Ramakrishnan, Rajasekhar ^d   Sattler, Wolfgang ^a   Breslow, Jan L ^b   Zechner, Rudolf ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b ROCKEFELLER UNIVERSITY   (United States)

^c UNIVERSITY OF ARIZONA   (United States)

^d Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; CHOLESTEROL; CHOLESTEROL ESTER; DNA; HEPARIN; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOPROTEIN; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; RETINOL ACETATE; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL TISSUE; ARTICLE; CATABOLISM; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL ELECTROPHORESIS; LIPOPROTEIN METABOLISM; MALE; MOUSE; MUTANT; NONHUMAN; PLASMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SKELETAL MUSCLE; TRANSGENE;

ANIMALS; CHOLESTEROL, HDL; ENERGY METABOLISM; FEMALE; GENOTYPE; HEPARIN; HUMANS; LIPIDS; LIPOPROTEIN LIPASE; LIPOPROTEINS; MALE; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; MUSCLES; TRIGLYCERIDES;

ANIMALIA; MUS MUSCULUS;

EID: 0030757251     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.27.17182     Document Type: Article

References (59)

1. Goldberg, I. J. (1996) J. Lipid Res. 37, 693-707
2. Olivecrona, T., and Bengtsson-Olivecrona, G. (1987) in Lipoprotein Lipase (Borensztajn, J., ed) pp. 15-25, Evener, Chicago
3. Olivecrona, T., and Bengtsson-Olivecrona, G. (1993) Curr. Opin. Lipidol. 4, 187-196
4. Cryer A. (1985) Reprod. Nat. Dev. 25, 255-270
5. Rogers, M. P., and Robinson, D. S. (1974) J. Lipid Res. 15, 263-272
6. Eisenberg, S. (1984) J. Lipid Res. 25, 1017-1058
7. Eisenberg, S., Sehayek, E., Olivecrona, T., and Vlodavsky, I. (1992) J. Clin. Invest. 90, 2013-2021
8. Saxena, U., Klein, M. G., Vanni, T. M., and Goldberg, I. J. (1992) J. Clin. Invest. 89, 373-380
9. Wion, K. L, Kirchgessner, T. G., Lusis, A. J., Schotz, M. C., and Lawn, R. M. (1987) Science 235, 1638-1641
10. Zechner, R., Newman, C., Steiner, E., and Breslow, J. L. (1991) Genomics 11, 62-76
11. Schotz, M. C., and Garfinkel, A. S. (1972) Biochim. Biophys. Acta 270, 472-478
12. Borensztajn, J., Otways, S., and Robinson, J. S. (1970) J. Lipid Res. 11, 102-110
13. Gruen, R., Hietanen, E., and Greenwood, M. R. C. (1979) Metabolism 27, 1955-1966
14. Eckel, R. (1987) in Lipoprotein Lipase (Borensztajn, J., ed) pp. 79-132, Evener, Chicago
15. Greenwood, M. R. C. (1984) Int. J. Obesity 8, 561-569
16. Greenwood M. R. C. (1985) Int. J. Obesity 9, Suppl. 1, 67-70
17. Weinstock, P. H., Bisgaier, C. L., Aalto-Setälä, K. A., Radner, H., Ramakrishnan, R., Levak-Frank, S., Essenberg, A. D., Zechner, R., and Breslow J. L. (1995) J. Clin. Invest. 96, 2555-2568
18. Levak-Frank, S., Radner, H., Walsh, A., Stollberger, R., Knipping, G., Hoefler, G., Sattler, W., Weinstock, P. H., Breslow, J. L., and Zechner, R. (1995) J. Clin. Invest. 96, 976-986
19. Chomczynski, P., and Sacchi, N. (1987) Anal. Biochem. 162, 156-159
20. Babirak, S. P., Iverius, P. H., Fujimoto, W. Y., and Brunzell, J. D. (1989) Arteriosclerosis 9, 326-334
21. Ruotolo, G., Zhang, H., Bentsianov, V., and Le, N.-A. (1992) J. Lipid Res. 33, 1541-1549
22. Hayek, T., Chajek-Shaul, T., Walsh, A., Azrolan, N., and Breslow, J. L. (1991) Arterioscler. Thromb. 11, 1295-1302
23. Blanche, P. J., Gong, E. L., Forte, T. M., and Nichols, A. V. (1981) Biochim. Biophys. Acta 665, 408-418
24. Verdery, R. B., Benham, D. F., Baldwin, H. L., Goldberg, A. P., and Nichols, A. V. (1989) J. Lipid Res. 30, 1085-1095
25. Eckel, R. H., and Robbins, R. J. (1984) Proc. Natl. Acad. Sci. U.S.A. 81, 7604-7607
26. Jensen, G. L., Baly, D. L., Brannon, P. M., and Bensadoun, A. (1980) J. Biol. Chem. 255, 11141-11148
27. Vilaro, S., Llobera, M., Bengtsson-Olivecrona, G., and Olivecrona, T. (1988) Biochem. J. 249, 549-556
28. Kirchgessner, T. G., Svenson, K. L., Lusis, A. J., and Schotz, M. C. (1987) J. Biol. Chem. 262, 8463-8466
29. Brunzell, J. D. (1989) in The Metabolic Basis of Inherited Disease (Scriver, R. S., Beaudet, A. L., Sly, W. S., and Valu, D., eds) pp. 1165-1180, McGraw-Hill, New York
30. Brun, L. D., Gagne, C., Julien, P., Tremblay, A., Moorjani, S., Bouchard, C., and Lupien, P. J. (1989) Metabolism 38, 1005-1009
31. Huttunen, J. K., Ehnholm, C., Kekki, M., and Nikkilä, E. A. (1976) Clin. Sci. Mol. Med. 50, 49-260
32. Applebaum-Bowden, D., Haffner, S. M., Wahl, P. W., Warnick, G. R., Albers, J. J., and Hazzard, W. R. (1985) Arteriosclerosis 5, 273-282
33. Tornvall, P., Olivecrona, G., Karpe, F., Hamsten, A., and Olivecrona, T. (1995) Arterioscler. Thromb. Vasc. Biol. 15, 1086-1093
34. Taskinen, M.-R. (1987) in Lipoprotein Lipase (Borensztajn, J., ed) pp. 247-375, Evener, Chicago
35. Bosello, O., Cigolini, M., Battaggia, A., Ferrari, F., Miccioli, R., Olivetti, R., and Corsato, M. (1984) Int. J. Obesity 8, 213-220
36. Lithell, H. (1977) Acta Univ. Ups. 272
37. Rössner, S., Eklund, B., Kaijser, L., Olsson, A. G., and Walldius, G. (1976) Eur. J. Clin. Invest. 6, 299-305
38. Seip, R. L., Angelopoulos, T. J., and Semenkovich, C. F. (1995) Am. J. Physiol. 268, E229-E236
39. Odonkor, J. N., and Rogers, M. P. (1984) Biochem. Pharmacol. 33, 1337-1341
40. Vessby, B., Lithell, H., and Ledermann, H. (1982) Atherosclerosis 44, 113-118
41. Ohrvall, M., Lithell, H., Johansson, J., and Vessby, B. (1995) Metabolism 44, 212-217
42. Takahashi, S., Kawarabayasi, Y., Nakai, T., Sakai, J., and Yamamoto, T. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 9252-9256
43. Gavfels, M. E., Caird, M., Britt, D., Jackson, C. L., Patterson, D., and Strauss, J. F. (1993) Somat. Cell Mol. Genet. 3, 557-569
44. Nikkilä, E. A., Taskinen, M. R., and Kekki, M. (1978) Atherosclerosis 29, 497-501
45. Taskinen, M. R., and Nikkilä, E. A. (1981) Clin. Chim. Acta 112, 325-332
46. Austin, M. (1991) Arterioscler. Thromb. 11, 2-14
47. Mailly, F., Tugrul, Y., Reymer, P. W. A., Bruin, T., Seed, M., Groenemeyer, B. F., Asplund-Carlson, A., Vallance, D., Winder, A. F., Miller, G. J., Kastelein, J. J. P., Hamsten, A., Olivecrona, G., Humphries, S. E., and Talmud. P. (1995) Arterioscler. Thromb. Vasc. Biol. 15, 468-478
48. Reymer, P. W. A, Gagne, E., Groenemeyer, B. E., Zhang, H., Forsyth, I., Jansen, H., Seidell, J. C., Kromhout, D., Lie, K. E., Kastelein, J., and Hayden, M. R. (1995) Nat. Genet. 10, 28-34
49. Coleman, T., Seip, R. L., Gimble, J. M., Lee, D., Maeda, N., and Semenkovich, C. F. (1995) J. Biol. Chem. 270, 12518-12525
50. Shimada, M., Shimano, H., Gotoda, T., Yamamoto, K., Kawamura, M., Inaba, T., Yazaki, Y., and Yamada, N. (1993) J. Biol. Chem. 268, 17924-17929
51. Liu, M.-S., Jirik, F. R., LeBoeuf, R. C., Henderson, H., Castellani, L. W., Lusis, A. J., Ma, Y., Forsythe, I. J., Zhang, H., Kirk, E., Brunzell, J. D., and Hayden M. R. (1994) J. Biol. Chem. 269, 11417-11424
52. Zsigmond, E., Scheffler, E., Forte, T. M., Potenz, R., Wu, W., and Chan, L. (1994) J. Biol Chem. 269, 18757-18766
53. Brinton, E. A, Eisenberg, E., and Breslow J. L. (1994) Arterioscler. Thromb. Vasc. Biol. 14, 707-720
54. Stein, O., Friedman, G., Chajck-Shaul, T., Halperin, G., Olivecrona, T., and Stein, Y. (1983) Biochim. Biophys. Acta 750, 306-316
55. Beisiegel, U., Weber, W., and Bengtsson-Olivecrona, G. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 8342-8346
56. Chappell, D. A., Fry, G. L., Waknitz, M. A., Iverius, P.-H., Williams, S. E., and Strickland, D. K. (1992) J. Biol. Chem. 267, 25764-25767
57. Mathews C. H. (1957) Phys. Med. Biol. 2, 36-43
58. Miesenböck, G., Hölzl, B., Föger, B., Brandstätter, E., Paulweber, B., Sandhofer, F., and Patsch, J. R. (1993) J. Clin. Invest. 91, 448-455
59. Wilson, D. E., Emi, M., Iverius, P.-H., Hata, A., Wu, L. L., Hillas, E., Williams, R. R., and Lalouel, J.-M. (1990) J. Clin. Invest. 86, 735-750