Effects of the biological clock gene Bmal1 on tumour growth and anti-cancer drug activity

Journal of Biochemistry

Volumn 148, Issue 3, 2010, Pages 319-326

  Zeng, Zhao Lei ^a   Wu, Ming Wei ^a   Sun, Jian ^a   Sun, Yue Li ^a   Cai, Yu Chen ^a   Huang, Yi Jun ^b   Xian, Li Jian ^a  

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

anti cancer drugs; Bmal1; circadian rhythm; clock gene; colon cancer

Indexed keywords

CISPLATIN; CYCLIN A; CYCLIN B1; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN E; DOCETAXEL; ETOPOSIDE; MYC PROTEIN; PER1 PROTEIN; PER2 PROTEIN; PER3 PROTEIN; PROTEIN; PROTEIN BMAL1; PROTEIN P21; PROTEIN P53; UNCLASSIFIED DRUG; WEE1 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOLOGICAL RHYTHM; CANCER CELL; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CELL STRAIN L 929; CELLULAR DISTRIBUTION; CIRCADIAN RHYTHM; COLON CANCER; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; GENE EXPRESSION REGULATION; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT GENE; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RNA INTERFERENCE; TREATMENT RESPONSE; TUMOR GROWTH;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; ARNTL TRANSCRIPTION FACTORS; BIOLOGICAL CLOCKS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; DNA REPAIR; DOWN-REGULATION; FIBROBLASTS; HOMEOSTASIS; MICE; RNA, SMALL INTERFERING;

MURINAE; MUS;

EID: 77956426309     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvq069     Document Type: Article

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