Two sequential cleavage reactions on cruciform DNA structures cause palindrome-mediated chromosomal translocations

Nature Communications

Volumn 4, Issue , 2013, Pages

  Inagaki, Hidehito ^a   Ohye, Tamae ^a   Kogo, Hiroshi ^a   Tsutsumi, Makiko ^a   Kato, Takema ^a,b,c   Tong, Maoqing ^a   Emanuel, Beverly S ^b,c   Kurahashi, Hiroki ^a  

^a FUJITA HEALTH UNIVERSITY   (Japan)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CHROMOSOME; DNA; RECOMBINATION; TRANSLOCATION;

ARTICLE; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DNA CLEAVAGE; DNA CONFORMATION; DNA END JOINING REPAIR; DNA HAIRPIN; DNA SEQUENCE; DNA STRUCTURE; GENE EXPRESSION; HOMOLOGOUS RECOMBINATION; HUMAN; HUMAN CELL; SIGNAL TRANSDUCTION; SPERM;

AT RICH SEQUENCE; BASE SEQUENCE; BLOTTING, SOUTHERN; CHROMOSOME BREAKAGE; DNA, CRUCIFORM; GENE KNOCKDOWN TECHNIQUES; GENE REARRANGEMENT; HEK293 CELLS; HOLLIDAY JUNCTION RESOLVASES; HUMANS; INVERTED REPEAT SEQUENCES; MALE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; NUCLEOTIDES; SPERMATOZOA; TRANSLOCATION, GENETIC;

EID: 84875847199     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms2595     Document Type: Article

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