Long AT-rich palindromes and the constitutional t(11;22) breakpoint

Human Molecular Genetics

Volumn 10, Issue 23, 2001, Pages 2605-2617

  Kurahashi, Hiroki ^a   Emanuel, Beverly S ^a,b,c  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CRUCIFORM DNA; DOUBLE STRANDED DNA; NUCLEOTIDE; PALINDROMIC DNA; REPETITIVE DNA; THYMINE;

ALLELE; ARTICLE; AT RICH SEQUENCE; BASE MISPAIRING; BASE PAIRING; CHROMOSOME 11; CHROMOSOME 11Q; CHROMOSOME 22; CHROMOSOME 22Q; CHROMOSOME BREAKAGE; CHROMOSOME DELETION; CHROMOSOME POLYMORPHISM; CHROMOSOME STRUCTURE; CHROMOSOME TRANSLOCATION 11; CHROMOSOME TRANSLOCATION 22; CHROMOSOME VARIANT; CONTROLLED STUDY; DNA RECOMBINATION; DNA SEQUENCE; DNA STRAND BREAKAGE; HUMAN; HUMAN CELL; MALE; MEIOSIS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; ROBERTSONIAN CHROMOSOME TRANSLOCATION; SAMPLE; SEQUENCE ANALYSIS; SPERM;

EID: 0035509701     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/10.23.2605     Document Type: Article

References (25)

1. Clustered 11q23 and 22q11 breakpoints and 3:1 meiotic malsegregation in multiple unrelated t(11;22) families
2. Regions of genomic instability on 22q11 and 11q23 as the etiology for the recurrent constitutional t(11;22)
3. Tightly clustered 11q23 and 22q11 breakpoints permit PCR-based detection of the recurrent constitutional t(11;22)
4. AT-rich palindromes mediate the constitutional t(11;22) translocation
5. The DNA sequence of human chromosome 22
6. Chromosome 22-specific low copy repeats and the 22q11.2 deletion syndrome: Genomic organization and deletion endpoint analysis
7. Der(22) syndrome and velo-cardio-facial syndrome/DiGeorge syndrome share a 1.5-Mb region of overlap on chromosome 22q11
8. Evolutionarily conserved low copy repeats (LCRs) in 22q11 mediate deletions, duplications, translocations, and genomic instability: An update and literature review
9. Long DNA palindromes, cruciform structures, genetic instability and secondary structure repair
10. Escherichia coli host strains SURE and SRB fail to preserve a palindrome cloned in λ phage: Improved alternate host strains
11. Long palindromes formed in Streptomyces by nonrecombinational intra-strand annealing
12. Unexpectedly high rate of de novo constitutional t(11;22) translocations in sperm from normal males
13. Clustering of DiGeorge/velocardiofacial-associated translocations suggestive of a translocation 'hotspot'
14. The second case of a t(17;22) in a family with neurofibromatosis type 1: Sequence analysis of the breakpoint regions
15. Molecular studies of an ependymoma-associated constitutional t(1;22)(p22;q11.2) Cytogenet. Cell
16. Palindrome resolution and recombination in the mammalian germ line
17. Instability of long inverted repeats within mouse transgenes
18. Palindromy is eliminated through a structure-specific recombination process in rodent cells
19. Fine mapping of the constitutional translocation t(11;22)(q23;q11)
20. The SbcCD nuclease of Escherichia coli is a structural maintenance of chromosomes (SMC) family protein that cleaves hairpin DNA
21. Structural and functional similarities between the SbcCD proteins of Escherichia coli and the RAD50 and MRE11 (RAD32) recombination and repair proteins of yeast
22. DNA double-strand breaks: Signaling, repair and the cancer connection
23. Frequent chromosomal translocations induced by DNA double-strand breaks
24. Trinucleotide models for DNA bending propensity: Comparison of models based on DNasel digestion and nucleosome packaging data
25. Capture of retrotransposon DNA at the sites of chromosomal double-strand breaks