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Volumn 7, Issue 4, 2012, Pages 1025-1033

Dextromethorphan attenuated inflammation and combined opioid use in humans undergoing methadone maintenance treatment

Author keywords

Cytokines; Dextromethorphan; Methadone maintenance therapy; Opioid; Plasma

Indexed keywords

DEXTROMETHORPHAN; DIAMORPHINE; INTERLEUKIN 8; METHADONE; MORPHINE; TUMOR NECROSIS FACTOR ALPHA;

EID: 84875829064     PISSN: 15571890     EISSN: 15571904     Source Type: Journal    
DOI: 10.1007/s11481-012-9400-1     Document Type: Article
Times cited : (24)

References (55)
  • 1
    • 79957799755 scopus 로고    scopus 로고
    • Sigma-1 receptor ligand PRE-084 reduced infarct volume, neurological deficits, pro-inflammatory cytokines and enhanced anti-inflammatory cytokines after embolic stroke in rats
    • Allahtavakoli M, Jarrott B (2011) Sigma-1 receptor ligand PRE-084 reduced infarct volume, neurological deficits, pro-inflammatory cytokines and enhanced anti-inflammatory cytokines after embolic stroke in rats. Brain Res Bull 85(3-4):219-24
    • (2011) Brain Res Bull , vol.85 , Issue.3-4 , pp. 219-224
    • Allahtavakoli, M.1    Jarrott, B.2
  • 2
    • 84870469320 scopus 로고    scopus 로고
    • American Psychiatric Association 4th edn. Washington: American Psychiatric Association
    • American Psychiatric Association (2000) Diagnostic and Statistical Manual of Mental Disorder-IV-TR, 4th edn. Washington: American Psychiatric Association
    • (2000) Diagnostic and Statistical Manual of Mental Disorder-IV-TR
  • 3
    • 0029901578 scopus 로고    scopus 로고
    • Central opiate modulation of peripheral IL-6 in rats
    • 8817528 10.1097/00001756-199604260-00017 1:CAS:528:DyaK28XntV2mtro%3D
    • Bertolucci M, Perego C, De Simoni MG (1996) Central opiate modulation of peripheral IL-6 in rats. Neuroreport 7:1181-1184
    • (1996) Neuroreport , vol.7 , pp. 1181-1184
    • Bertolucci, M.1    Perego, C.2    De Simoni, M.G.3
  • 4
    • 17944389555 scopus 로고    scopus 로고
    • Opiate withdrawal with dextromethorphan
    • 9090360 1:STN:280:DyaK2s3ksFKqsA%3D%3D
    • Bisaga A, Gianelli P, Popik P (1997) Opiate withdrawal with dextromethorphan. Am J Psychiatry 154:584
    • (1997) Am J Psychiatry , vol.154 , pp. 584
    • Bisaga, A.1    Gianelli, P.2    Popik, P.3
  • 5
    • 0024553608 scopus 로고
    • Evidence for a multi-site model of the rat brain sigma receptor
    • 2542066 10.1016/0014-2999(89)90200-8 1:CAS:528:DyaL1MXktlGru70%3D
    • Bowen WD, Hellewell SB, McGarry KA (1989) Evidence for a multi-site model of the rat brain sigma receptor. Eur J Pharmacol 163:309-318
    • (1989) Eur J Pharmacol , vol.163 , pp. 309-318
    • Bowen, W.D.1    Hellewell, S.B.2    McGarry, K.A.3
  • 6
    • 0020085273 scopus 로고
    • Topographical distribution of possible glutamatergic pathways from the frontal cortex to the striatum and substantia nigra in rats
    • 7110527 10.1016/0028-3908(82)90019-3 1:CAS:528:DyaL38Xks1Krtrw%3D
    • Carter CJ (1982) Topographical distribution of possible glutamatergic pathways from the frontal cortex to the striatum and substantia nigra in rats. Neuropharmacology 21:379-383
    • (1982) Neuropharmacology , vol.21 , pp. 379-383
    • Carter, C.J.1
  • 7
    • 14644404349 scopus 로고    scopus 로고
    • Dextromethorphan differentially affects opioid antinociception in rats
    • 15655510 10.1038/sj.bjp.0706086 1:CAS:528:DC%2BD2MXhtVGmsLw%3D
    • Chen SL, Huang EY, Chow LH, Tao PL (2005) Dextromethorphan differentially affects opioid antinociception in rats. Br J Pharmacol 144:400-404
    • (2005) Br J Pharmacol , vol.144 , pp. 400-404
    • Chen, S.L.1    Huang, E.Y.2    Chow, L.H.3    Tao, P.L.4
  • 8
    • 79960840358 scopus 로고    scopus 로고
    • Low doses of dextromethorphan attenuate morphine-induced rewarding via the sigma-1 receptor at ventral tegmental area in rats
    • Chen SL, Hsu KY, Huang EY, Lu RB, Tao PL (2011) Low doses of dextromethorphan attenuate morphine-induced rewarding via the sigma-1 receptor at ventral tegmental area in rats. Drug Alcohol Depend 117(2-3):164-9
    • (2011) Drug Alcohol Depend , vol.117 , Issue.2-3 , pp. 164-169
    • Chen, S.L.1    Hsu, K.Y.2    Huang, E.Y.3    Lu, R.B.4    Tao, P.L.5
  • 9
    • 84863327882 scopus 로고    scopus 로고
    • Low-dose memantine attenuated morphine addictive behavior through its anti-inflammation and neurotrophic effects in rats
    • 22205542 10.1007/s11481-011-9337-9
    • Chen SL, Tao PL, Chu CH, Chen SH, Wu HE, Tseng LF, Hong JS, Lu RB (2012a) Low-dose memantine attenuated morphine addictive behavior through its anti-inflammation and neurotrophic effects in rats. J Neuroimmune Pharmacol 7:444-453
    • (2012) J Neuroimmune Pharmacol , vol.7 , pp. 444-453
    • Chen, S.L.1    Tao, P.L.2    Chu, C.H.3    Chen, S.H.4    Wu, H.E.5    Tseng, L.F.6    Hong, J.S.7    Lu, R.B.8
  • 11
    • 38849175611 scopus 로고    scopus 로고
    • Chronic morphine-induced neuronal morphological changes in the ventral tegmental area in rats are reversed by electroacupuncture treatment
    • 18269380 10.1111/j.1369-1600.2007.00092.x
    • Chu NN, Xia W, Yu P, Hu L, Zhang R, Cui CL (2008) Chronic morphine-induced neuronal morphological changes in the ventral tegmental area in rats are reversed by electroacupuncture treatment. Addict Biol 13:47-51
    • (2008) Addict Biol , vol.13 , pp. 47-51
    • Chu, N.N.1    Xia, W.2    Yu, P.3    Hu, L.4    Zhang, R.5    Cui, C.L.6
  • 12
    • 0027970898 scopus 로고
    • Interactions of dextromethorphan with the N-methyl-D-aspartate receptor-channel complex: Single channel recordings
    • 7533633 10.1016/0006-8993(94)90771-4 1:CAS:528:DyaK2MXisFars7o%3D
    • Church J, Sawyer D, McLarnon JG (1994) Interactions of dextromethorphan with the N-methyl-D-aspartate receptor-channel complex: single channel recordings. Brain Res 666:189-194
    • (1994) Brain Res , vol.666 , pp. 189-194
    • Church, J.1    Sawyer, D.2    McLarnon, J.G.3
  • 14
    • 77955661837 scopus 로고    scopus 로고
    • Neurotoxicity of heroin-cocaine combinations in rat cortical neurons
    • 20600547 10.1016/j.tox.2010.06.009 1:CAS:528:DC%2BC3cXhtVehs77L
    • Cunha-Oliveira T, Rego AC, Garrido J, Borges F, Macedo T, Oliveira CR (2010) Neurotoxicity of heroin-cocaine combinations in rat cortical neurons. Toxicology 276:11-17
    • (2010) Toxicology , vol.276 , pp. 11-17
    • Cunha-Oliveira, T.1    Rego, A.C.2    Garrido, J.3    Borges, F.4    Macedo, T.5    Oliveira, C.R.6
  • 15
    • 58549111377 scopus 로고    scopus 로고
    • Histo- and immunocytochemical detection of inducible NOS and TNF-alpha in the locus coeruleus of human opiate addicts
    • 19038328 10.1016/j.jchemneu.2008.10.005 1:CAS:528:DC%2BD1MXhtlOitbk%3D
    • Dyuizen I, Lamash NE (2009) Histo- and immunocytochemical detection of inducible NOS and TNF-alpha in the locus coeruleus of human opiate addicts. J Chem Neuroanat 37:65-70
    • (2009) J Chem Neuroanat , vol.37 , pp. 65-70
    • Dyuizen, I.1    Lamash, N.E.2
  • 16
    • 0034691066 scopus 로고    scopus 로고
    • Opiates inhibit neurogenesis in the adult rat hippocampus
    • 10840056 10.1073/pnas.120552597 1:CAS:528:DC%2BD3cXksVKhsLY%3D
    • Eisch AJ, Barrot M, Schad CA, Self DW, Nestler EJ (2000) Opiates inhibit neurogenesis in the adult rat hippocampus. Proc Natl Acad Sci U S A 97:7579-7584
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 7579-7584
    • Eisch, A.J.1    Barrot, M.2    Schad, C.A.3    Self, D.W.4    Nestler, E.J.5
  • 17
    • 66249137770 scopus 로고    scopus 로고
    • Sigma receptors suppress multiple aspects of microglial activation
    • 19031439 10.1002/glia.20802
    • Hall AA, Herrera Y, Ajmo CT Jr, Cuevas J, Pennypacker KR (2009) Sigma receptors suppress multiple aspects of microglial activation. Glia 57:744-754
    • (2009) Glia , vol.57 , pp. 744-754
    • Hall, A.A.1    Herrera, Y.2    Ajmo Jr., C.T.3    Cuevas, J.4    Pennypacker, K.R.5
  • 18
    • 0036137091 scopus 로고    scopus 로고
    • Rapid elevation of plasma interleukin-6 by morphine is dependent on autonomic stimulation of adrenal gland
    • 11752119 10.1124/jpet.300.1.213 1:CAS:528:DC%2BD38Xht1Wmtw%3D%3D
    • Houghtling RA, Bayer BM (2002) Rapid elevation of plasma interleukin-6 by morphine is dependent on autonomic stimulation of adrenal gland. J Pharmacol Exp Ther 300:213-219
    • (2002) J Pharmacol Exp Ther , vol.300 , pp. 213-219
    • Houghtling, R.A.1    Bayer, B.M.2
  • 19
    • 0345376225 scopus 로고    scopus 로고
    • Co-administration of dextromethorphan with morphine attenuates morphine rewarding effect and related dopamine releases at the nucleus accumbens
    • 14564449 10.1007/s00210-003-0803-7 1:CAS:528:DC%2BD3sXovFOitrk%3D
    • Huang EY, Liu TC, Tao PL (2003) Co-administration of dextromethorphan with morphine attenuates morphine rewarding effect and related dopamine releases at the nucleus accumbens. Naunyn Schmiedebergs Arch Pharmacol 368:386-392
    • (2003) Naunyn Schmiedebergs Arch Pharmacol , vol.368 , pp. 386-392
    • Huang, E.Y.1    Liu, T.C.2    Tao, P.L.3
  • 20
    • 1642333101 scopus 로고    scopus 로고
    • Possible interaction of alcohol dehydrogenase and aldehyde dehydrogenase genes with the dopamine D2 receptor gene in anxiety-depressive alcohol dependence
    • 15084894 10.1097/01.ALC.0000117832.62901.61 1:CAS:528: DC%2BD2cXjsFSktr0%3D
    • Huang SY, Lin WW, Ko HC, Lee JF, Wang TJ, Chou YH, Yin SJ, Lu RB (2004) Possible interaction of alcohol dehydrogenase and aldehyde dehydrogenase genes with the dopamine D2 receptor gene in anxiety-depressive alcohol dependence. Alcohol Clin Exp Res 28:374-384
    • (2004) Alcohol Clin Exp Res , vol.28 , pp. 374-384
    • Huang, S.Y.1    Lin, W.W.2    Ko, H.C.3    Lee, J.F.4    Wang, T.J.5    Chou, Y.H.6    Yin, S.J.7    Lu, R.B.8
  • 21
    • 0033936026 scopus 로고    scopus 로고
    • Morphine stimulates mesangial cell TNF-alpha and nitrite production
    • 10921509 10.1023/A:1007016329300 1:CAS:528:DC%2BD3cXlsVGjtLs%3D
    • Kapasi AA, Gibbons N, Mattana J, Singhal PC (2000) Morphine stimulates mesangial cell TNF-alpha and nitrite production. Inflammation 24:463-476
    • (2000) Inflammation , vol.24 , pp. 463-476
    • Kapasi, A.A.1    Gibbons, N.2    Mattana, J.3    Singhal, P.C.4
  • 22
  • 23
    • 0002619224 scopus 로고
    • The treatment with dextromethorphan of heroin addicts
    • N. Loimer R. Schmid A. Springer (eds) Springer Vienna 10.1007/978-3-7091-9173-6-38
    • Koyuncuoglu H (1991) The treatment with dextromethorphan of heroin addicts. In: Loimer N, Schmid R, Springer A (eds) Drug addiction and AIDS. Springer, Vienna, pp 320-329
    • (1991) Drug Addiction and AIDS , pp. 320-329
    • Koyuncuoglu, H.1
  • 24
    • 41149089597 scopus 로고    scopus 로고
    • Glutamate release in the nucleus accumbens core is necessary for heroin seeking
    • 18354020 10.1523/JNEUROSCI.5129-07.2008 1:CAS:528:DC%2BD1cXjvFCjsbc%3D
    • LaLumiere RT, Kalivas PW (2008) Glutamate release in the nucleus accumbens core is necessary for heroin seeking. J Neurosci 28:3170-3177
    • (2008) J Neurosci , vol.28 , pp. 3170-3177
    • Lalumiere, R.T.1    Kalivas, P.W.2
  • 25
    • 16344374513 scopus 로고    scopus 로고
    • Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage
    • 15790998 10.1096/fj.04-2555com 1:CAS:528:DC%2BD2MXjtFaqsro%3D
    • Li G, Cui G, Tzeng NS, Wei SJ, Wang T, Block ML, Hong JS (2005) Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage. FASEB J 19:489-496
    • (2005) FASEB J , vol.19 , pp. 489-496
    • Li, G.1    Cui, G.2    Tzeng, N.S.3    Wei, S.J.4    Wang, T.5    Block, M.L.6    Hong, J.S.7
  • 26
    • 79952321922 scopus 로고    scopus 로고
    • Dextromethorphan efficiently increases bactericidal activity, attenuates inflammatory responses, and prevents group a streptococcal sepsis
    • 21199930 10.1128/AAC.00950-10 1:CAS:528:DC%2BC3MXktlamtrk%3D
    • Li MH, Luo YH, Lin CF, Chang YT, Lu SL, Kuo CF, Hong JS, Lin YS (2011) Dextromethorphan efficiently increases bactericidal activity, attenuates inflammatory responses, and prevents group a streptococcal sepsis. Antimicrob Agents Chemother 55:967-973
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 967-973
    • Li, M.H.1    Luo, Y.H.2    Lin, C.F.3    Chang, Y.T.4    Lu, S.L.5    Kuo, C.F.6    Hong, J.S.7    Lin, Y.S.8
  • 27
    • 0037381043 scopus 로고    scopus 로고
    • Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation
    • 12649371 10.1124/jpet.102.043166 1:CAS:528:DC%2BD3sXis1anurk%3D
    • Liu Y, Qin L, Li G, Zhang W, An L, Liu B, Hong JS (2003) Dextromethorphan protects dopaminergic neurons against inflammation-mediated degeneration through inhibition of microglial activation. J Pharmacol Exp Ther 305:212-218
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 212-218
    • Liu, Y.1    Qin, L.2    Li, G.3    Zhang, W.4    An, L.5    Liu, B.6    Hong, J.S.7
  • 28
    • 52449084260 scopus 로고    scopus 로고
    • Treatment with dextromethorphan improves endothelial function, inflammation and oxidative stress in male heavy smokers
    • 18647232 10.1111/j.1538-7836.2008.03082.x 1:CAS:528:DC%2BD1cXhtlaitLvP
    • Liu PY, Lin CC, Tsai WC, Li YH, Lin LJ, Shi GY, Hong JS, Chen JH, Wu HL (2008) Treatment with dextromethorphan improves endothelial function, inflammation and oxidative stress in male heavy smokers. J Thromb Haemost 6:1685-1692
    • (2008) J Thromb Haemost , vol.6 , pp. 1685-1692
    • Liu, P.Y.1    Lin, C.C.2    Tsai, W.C.3    Li, Y.H.4    Lin, L.J.5    Shi, G.Y.6    Hong, J.S.7    Chen, J.H.8    Wu, H.L.9
  • 29
    • 34147165507 scopus 로고    scopus 로고
    • Post-treatment of dextromethorphan reverses morphine effect on conditioned place preference in rats
    • 17372963 10.1002/syn.20391 1:CAS:528:DC%2BD2sXktlKqu7s%3D
    • Lue WM, Huang EY, Yang SN, Wong CS, Tao PL (2007) Post-treatment of dextromethorphan reverses morphine effect on conditioned place preference in rats. Synapse 61:420-428
    • (2007) Synapse , vol.61 , pp. 420-428
    • Lue, W.M.1    Huang, E.Y.2    Yang, S.N.3    Wong, C.S.4    Tao, P.L.5
  • 30
    • 0017064976 scopus 로고
    • The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog
    • 945347 1:CAS:528:DyaE28XltlOhurw%3D
    • Martin WR, Eades CG, Thompson JA, Huppler RE, Gilbert PE (1976) The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog. J Pharmacol Exp Ther 197:517-532
    • (1976) J Pharmacol Exp Ther , vol.197 , pp. 517-532
    • Martin, W.R.1    Eades, C.G.2    Thompson, J.A.3    Huppler, R.E.4    Gilbert, P.E.5
  • 31
    • 0025001715 scopus 로고
    • Multiple sites of action of (+)-3-(3-hydroxyphenyl)-N-(1-propyl) piperidine ((+)-3PPP) in blood vessels
    • 2272368 10.1016/0014-2999(90)94193-2 1:CAS:528:DyaK3MXjsFykug%3D%3D
    • Massamiri T, Duckles SP (1990) Multiple sites of action of (+)-3-(3-hydroxyphenyl)-N-(1-propyl)piperidine ((+)-3PPP) in blood vessels. Eur J Pharmacol 190:295-303
    • (1990) Eur J Pharmacol , vol.190 , pp. 295-303
    • Massamiri, T.1    Duckles, S.P.2
  • 32
    • 0036606840 scopus 로고    scopus 로고
    • Cognitive impairment in methadone maintenance patients
    • 12062778 10.1016/S0376-8716(02)00013-3
    • Mintzer MZ, Stitzer ML (2002) Cognitive impairment in methadone maintenance patients. Drug Alcohol Depend 67:41-51
    • (2002) Drug Alcohol Depend , vol.67 , pp. 41-51
    • Mintzer, M.Z.1    Stitzer, M.L.2
  • 33
    • 0027254655 scopus 로고
    • Dextromethorphan blocks N-methyl-D-aspartate-induced currents and voltage-operated inward currents in cultured cortical neurons
    • 7691620 10.1016/0014-2999(93)90849-D 1:CAS:528:DyaK3sXlslCju7k%3D
    • Netzer R, Pflimlin P, Trube G (1993) Dextromethorphan blocks N-methyl-D-aspartate-induced currents and voltage-operated inward currents in cultured cortical neurons. Eur J Pharmacol 238:209-216
    • (1993) Eur J Pharmacol , vol.238 , pp. 209-216
    • Netzer, R.1    Pflimlin, P.2    Trube, G.3
  • 34
    • 0028344853 scopus 로고
    • Morphine amplifies HIV-1 expression in chronically infected promonocytes cocultured with human brain cells
    • 8120138 10.1016/0165-5728(94)90043-4 1:CAS:528:DyaK2cXivFKmt7g%3D
    • Peterson PK, Gekker G, Hu S, Anderson WR, Kravitz F, Portoghese PS, Balfour HH Jr, Chao CC (1994) Morphine amplifies HIV-1 expression in chronically infected promonocytes cocultured with human brain cells. J Neuroimmunol 50:167-175
    • (1994) J Neuroimmunol , vol.50 , pp. 167-175
    • Peterson, P.K.1    Gekker, G.2    Hu, S.3    Anderson, W.R.4    Kravitz, F.5    Portoghese, P.S.6    Balfour Jr., H.H.7    Chao, C.C.8
  • 35
    • 0032520728 scopus 로고    scopus 로고
    • The opioid-cytokine connection
    • 9610674 10.1016/S0165-5728(97)00222-1 1:CAS:528:DyaK1cXitlSrurY%3D
    • Peterson PK, Molitor TW, Chao CC (1998) The opioid-cytokine connection. J Neuroimmunol 83:63-69
    • (1998) J Neuroimmunol , vol.83 , pp. 63-69
    • Peterson, P.K.1    Molitor, T.W.2    Chao, C.C.3
  • 36
    • 68349125513 scopus 로고    scopus 로고
    • Sustained attention in patients receiving and abstinent following methadone maintenance treatment for opiate dependence: Performance and neuroimaging results
    • 19608356 10.1016/j.drugalcdep.2009.04.022 1:CAS:528:DC%2BD1MXpvFyrtb0%3D
    • Prosser J, London ED, Galynker II (2009) Sustained attention in patients receiving and abstinent following methadone maintenance treatment for opiate dependence: performance and neuroimaging results. Drug Alcohol Depend 104:228-240
    • (2009) Drug Alcohol Depend , vol.104 , pp. 228-240
    • Prosser, J.1    London, E.D.2    Galynker, I.I.3
  • 37
    • 33847759064 scopus 로고    scopus 로고
    • Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration
    • 17203472 10.1002/glia.20467
    • Qin L, Wu X, Block ML, Liu Y, Breese GR, Hong JS, Knapp DJ, Crews FT (2007) Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration. Glia 55:453-462
    • (2007) Glia , vol.55 , pp. 453-462
    • Qin, L.1    Wu, X.2    Block, M.L.3    Liu, Y.4    Breese, G.R.5    Hong, J.S.6    Knapp, D.J.7    Crews, F.T.8
  • 38
    • 0037112041 scopus 로고    scopus 로고
    • The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats
    • 12427855 1:CAS:528:DC%2BD38XovF2ksbg%3D
    • Raghavendra V, Rutkowski MD, DeLeo JA (2002) The role of spinal neuroimmune activation in morphine tolerance/hyperalgesia in neuropathic and sham-operated rats. J Neurosci 22:9980-9989
    • (2002) J Neurosci , vol.22 , pp. 9980-9989
    • Raghavendra, V.1    Rutkowski, M.D.2    Deleo, J.A.3
  • 39
    • 0842286586 scopus 로고    scopus 로고
    • Attenuation of morphine tolerance, withdrawal-induced hyperalgesia, and associated spinal inflammatory immune responses by propentofylline in rats
    • 14532913 10.1038/sj.npp.1300315 1:CAS:528:DC%2BD2cXksl2iuw%3D%3D
    • Raghavendra V, Tanga FY, DeLeo JA (2004) Attenuation of morphine tolerance, withdrawal-induced hyperalgesia, and associated spinal inflammatory immune responses by propentofylline in rats. Neuropsychopharmacology 29:327-334
    • (2004) Neuropsychopharmacology , vol.29 , pp. 327-334
    • Raghavendra, V.1    Tanga, F.Y.2    Deleo, J.A.3
  • 40
    • 0033566311 scopus 로고    scopus 로고
    • Morphine alters the structure of neurons in the nucleus accumbens and neocortex of rats
    • 10400894 10.1002/(SICI)1098-2396(199908)33:2<160: AID-SYN6>3.0. CO;2-S 1:CAS:528:DyaK1MXksFKqtLk%3D
    • Robinson TE, Kolb B (1999) Morphine alters the structure of neurons in the nucleus accumbens and neocortex of rats. Synapse 33:160-162
    • (1999) Synapse , vol.33 , pp. 160-162
    • Robinson, T.E.1    Kolb, B.2
  • 41
    • 0029621773 scopus 로고
    • Primary astroglial cultures derived from several rat brain regions differentially express mu, delta and kappa opioid receptor mRNA
    • 8750824 10.1016/0169-328X(95)00165-O 1:CAS:528:DyaK2MXhtVSgtb7O
    • Ruzicka BB, Fox CA, Thompson RC, Meng F, Watson SJ, Akil H (1995) Primary astroglial cultures derived from several rat brain regions differentially express mu, delta and kappa opioid receptor mRNA. Brain Res Mol Brain Res 34:209-220
    • (1995) Brain Res Mol Brain Res , vol.34 , pp. 209-220
    • Ruzicka, B.B.1    Fox, C.A.2    Thompson, R.C.3    Meng, F.4    Watson, S.J.5    Akil, H.6
  • 42
    • 37549060737 scopus 로고    scopus 로고
    • PET imaging of dopamine transporter and drug craving during methadone maintenance treatment and after prolonged abstinence in heroin users
    • 17977528 10.1016/j.ejphar.2007.09.042 1:CAS:528:DC%2BD1cXivVKgtw%3D%3D
    • Shi J, Zhao LY, Copersino ML, Fang YX, Chen Y, Tian J, Deng Y, Shuai Y, Jin J, Lu L (2008) PET imaging of dopamine transporter and drug craving during methadone maintenance treatment and after prolonged abstinence in heroin users. Eur J Pharmacol 579:160-166
    • (2008) Eur J Pharmacol , vol.579 , pp. 160-166
    • Shi, J.1    Zhao, L.Y.2    Copersino, M.L.3    Fang, Y.X.4    Chen, Y.5    Tian, J.6    Deng, Y.7    Shuai, Y.8    Jin, J.9    Lu, L.10
  • 44
    • 27244438637 scopus 로고    scopus 로고
    • Do pathogen exposure and innate immunity cause brain diseases?
    • 16197808 10.1179/016164105X49526 1:CAS:528:DC%2BD2MXht1Wkt7bL
    • Simard AR, Rivest S (2005) Do pathogen exposure and innate immunity cause brain diseases? Neurol Res 27:717-725
    • (2005) Neurol Res , vol.27 , pp. 717-725
    • Simard, A.R.1    Rivest, S.2
  • 45
    • 0029784475 scopus 로고    scopus 로고
    • Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons
    • 8855333 10.1073/pnas.93.20.11202 1:CAS:528:DyaK28XmtVOqs7k%3D
    • Sklair-Tavron L, Shi WX, Lane SB, Harris HW, Bunney BS, Nestler EJ (1996) Chronic morphine induces visible changes in the morphology of mesolimbic dopamine neurons. Proc Natl Acad Sci U S A 93:11202-11207
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 11202-11207
    • Sklair-Tavron, L.1    Shi, W.X.2    Lane, S.B.3    Harris, H.W.4    Bunney, B.S.5    Nestler, E.J.6
  • 46
    • 0019935002 scopus 로고
    • Evidence for sigma opioid receptor: Binding of [3H]SKF-10047 to etorphine-inaccessible sites in guinea-pig brain
    • 6290634 1:CAS:528:DyaL3sXksV0%3D
    • Su TP (1982) Evidence for sigma opioid receptor: binding of [3H]SKF-10047 to etorphine-inaccessible sites in guinea-pig brain. J Pharmacol Exp Ther 223:284-290
    • (1982) J Pharmacol Exp Ther , vol.223 , pp. 284-290
    • Su, T.P.1
  • 47
    • 79953041124 scopus 로고    scopus 로고
    • White matter impairment in heroin addicts undergoing methadone maintenance treatment and prolonged abstinence: A preliminary DTI study
    • 21362458 10.1016/j.neulet.2011.02.053 1:CAS:528:DC%2BC3MXjvFSrsLw%3D
    • Wang Y, Li W, Li Q, Yang W, Zhu J, Wang W (2011) White matter impairment in heroin addicts undergoing methadone maintenance treatment and prolonged abstinence: a preliminary DTI study. Neurosci Lett 494:49-53
    • (2011) Neurosci Lett , vol.494 , pp. 49-53
    • Wang, Y.1    Li, W.2    Li, Q.3    Yang, W.4    Zhu, J.5    Wang, W.6
  • 48
    • 0024243096 scopus 로고
    • Initial identification and characterization of sigma receptors on human peripheral blood leukocytes
    • 2849660 1:CAS:528:DyaL1MXovVCiug%3D%3D
    • Wolfe SA Jr, Kulsakdinun C, Battaglia G, Jaffe JH, De Souza EB (1988) Initial identification and characterization of sigma receptors on human peripheral blood leukocytes. J Pharmacol Exp Ther 247:1114-1119
    • (1988) J Pharmacol Exp Ther , vol.247 , pp. 1114-1119
    • Wolfe Jr., S.A.1    Kulsakdinun, C.2    Battaglia, G.3    Jaffe, J.H.4    De Souza, E.B.5
  • 49
    • 0024518488 scopus 로고
    • Sigma-receptors in endocrine organs: Identification, characterization, and autoradiographic localization in rat pituitary, adrenal, testis, and ovary
    • 2537173 10.1210/endo-124-3-1160 1:CAS:528:DyaL1MXhsVOks7k%3D
    • Wolfe SA Jr, Culp SG, De Souza EB (1989) Sigma-receptors in endocrine organs: identification, characterization, and autoradiographic localization in rat pituitary, adrenal, testis, and ovary. Endocrinology 124:1160-1172
    • (1989) Endocrinology , vol.124 , pp. 1160-1172
    • Wolfe Jr., S.A.1    Culp, S.G.2    De Souza, E.B.3
  • 50
    • 84863270536 scopus 로고    scopus 로고
    • Attenuating heat-induced acute lung inflammation and injury by dextromethorphan in rats
    • 22033269 10.1165/rcmb.2011-0226OC 1:CAS:528:DC%2BC38Xks1ertbY%3D
    • Yang HH, Hou CC, Lin MT, Chang CP (2012) Attenuating heat-induced acute lung inflammation and injury by dextromethorphan in rats. Am J Respir Cell Mol Biol 46:407-413
    • (2012) Am J Respir Cell Mol Biol , vol.46 , pp. 407-413
    • Yang, H.H.1    Hou, C.C.2    Lin, M.T.3    Chang, C.P.4
  • 51
    • 2442693172 scopus 로고    scopus 로고
    • Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: Role of NADPH oxidase
    • 14734632 1:CAS:528:DC%2BD2cXisV2itLk%3D
    • Zhang W, Wang T, Qin L, Gao HM, Wilson B, Ali SF, Hong JS, Liu B (2004) Neuroprotective effect of dextromethorphan in the MPTP Parkinson's disease model: role of NADPH oxidase. FASEB J 18:589-591
    • (2004) FASEB J , vol.18 , pp. 589-591
    • Zhang, W.1    Wang, T.2    Qin, L.3    Gao, H.M.4    Wilson, B.5    Ali, S.F.6    Hong, J.S.7    Liu, B.8
  • 52
    • 20044379940 scopus 로고    scopus 로고
    • 3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity
    • 15596482 1:CAS:528:DC%2BD2MXit1KlurY%3D
    • Zhang W, Qin L, Wang T, Wei SJ, Gao HM, Liu J, Wilson B, Liu B, Kim HC, Hong JS (2005) 3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity. FASEB J 19:395-397
    • (2005) FASEB J , vol.19 , pp. 395-397
    • Zhang, W.1    Qin, L.2    Wang, T.3    Wei, S.J.4    Gao, H.M.5    Liu, J.6    Wilson, B.7    Liu, B.8    Kim, H.C.9    Hong, J.S.10
  • 53
    • 33845603005 scopus 로고    scopus 로고
    • 3-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro
    • 17142799 10.1096/fj.06-6006com 1:CAS:528:DC%2BD28Xht1OmsLbO
    • Zhang W, Shin EJ, Wang T, Lee PH, Pang H, Wie MB, Kim WK, Kim SJ, Huang WH, Wang Y, Hong JS, Kim HC (2006) 3-Hydroxymorphinan, a metabolite of dextromethorphan, protects nigrostriatal pathway against MPTP-elicited damage both in vivo and in vitro. FASEB J 20:2496-2511
    • (2006) FASEB J , vol.20 , pp. 2496-2511
    • Zhang, W.1    Shin, E.J.2    Wang, T.3    Lee, P.H.4    Pang, H.5    Wie, M.B.6    Kim, W.K.7    Kim, S.J.8    Huang, W.H.9    Wang, Y.10    Hong, J.S.11    Kim, H.C.12
  • 55
    • 0034568984 scopus 로고    scopus 로고
    • Central single and chronic administration of morphine stimulates corticosterone and interleukin (IL)-6 in adjuvant-induced arthritis
    • 11220497 1:CAS:528:DC%2BD3MXot12rsg%3D%3D
    • Zubelewicz B, Muc-Wierzgon M, Harbuz MS, Brodziak A (2000) Central single and chronic administration of morphine stimulates corticosterone and interleukin (IL)-6 in adjuvant-induced arthritis. J Physiol Pharmacol 51:897-906
    • (2000) J Physiol Pharmacol , vol.51 , pp. 897-906
    • Zubelewicz, B.1    Muc-Wierzgon, M.2    Harbuz, M.S.3    Brodziak, A.4


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