STAT3 activity is necessary and sufficient for the development of immune-mediated myocarditis in mice and promotes progression to dilated cardiomyopathy

EMBO Molecular Medicine

Volumn 5, Issue 4, 2013, Pages 572-590

  Camporeale, Annalisa ^a   Marino, Francesca ^a   Papageorgiou, Anna ^b,c   Carai, Paolo ^b,d   Fornero, Sara ^a   Fletcher, Steven ^e   Page, Brent D G ^e   Gunning, Patrick ^e   Forni, Marco ^a   Chiarle, Roberto ^a   Morello, Mara ^f   Jensen, Ole ^g   Levi, Renzo ^a   Heymans, Stephane ^b,c,d   Poli, Valeria ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d ROYAL NETHERLANDS ACADEMY OF ARTS AND SCIENCES   (Netherlands)

^e UNIVERSITY OF TORONTO   (Canada)

^f UNIVERSITY OF TURIN   (Italy)

^g UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

Complement C3; Experimental autoimmune myocarditis; Immune mediated myocarditis; Interleukin 6; STAT3

Indexed keywords

CARDIAC AGENT; COMPLEMENT COMPONENT C3; IMMUNOLOGIC AGENT; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; NEUTRALIZING ANTIBODY; SFI 066; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DISEASE COURSE; EXPERIMENTAL AUTOIMMUNE MYOCARDITIS; FLOW CYTOMETRY; HEMATOPOIETIC CELL; IMMUNE MEDIATED INJURY; IMMUNOFLUORESCENCE TEST; LYMPHOCYTE PROLIFERATION; MOUSE; MYOCARDITIS; NONHUMAN; OUTCOME ASSESSMENT; PATHOGENESIS; PRIORITY JOURNAL;

ANIMALS; CARDIOMYOPATHY, DILATED; CD4-POSITIVE T-LYMPHOCYTES; COMPLEMENT C3; DISEASE PROGRESSION; FEMALE; HUMANS; INTERLEUKIN-6; LIVER; MALE; MICE; MICE, INBRED BALB C; MYOCARDITIS; STAT3 TRANSCRIPTION FACTOR; TH17 CELLS;

EID: 84875812252     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201201876     Document Type: Article

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