8-Oxo-2'-deoxyguanosine ameliorates UVB-induced skin damage in hairless mice by scavenging reactive oxygen species and inhibiting MMP expression

Journal of Dermatological Science

Volumn 70, Issue 1, 2013, Pages 49-57

  Lee, Jin Ku ^a   Ko, Seong Hee ^b   Ye, Sang Kyu ^a   Chung, Myung Hee ^a  

^a Seoul National University   (South Korea)

^b Sookmyung Women's University   (South Korea)

Author keywords

8 Oxo dG; MAPKs; MMPs; ROS; Ultraviolet B

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ACTIVATING TRANSCRIPTION FACTOR; ACTIVATING TRANSCRIPTION FACTOR 2; COLLAGENASE 3; GELATINASE B; HYDROGEN PEROXIDE; INTERSTITIAL COLLAGENASE; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXYNITRITE; PROTEIN C JUN; REACTIVE OXYGEN METABOLITE; SINGLET OXYGEN; SUPEROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EPIDERMIS HYPERPLASIA; FEMALE; HAIRLESS MOUSE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CARBONYLATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCAVENGING SYSTEM; SKIN DEFECT; SKIN PROTECTION; ULTRAVIOLET B RADIATION; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; CELL LINE; DEOXYGUANOSINE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; KERATINOCYTES; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 13; MATRIX METALLOPROTEINASE 9; MICE; MICE, HAIRLESS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SKIN AGING; ULTRAVIOLET RAYS;

EID: 84875809039     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2013.01.010     Document Type: Article

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