Plants as a source of butyrylcholinesterase variants designed for enhanced cocaine hydrolase activity

Chemico-Biological Interactions

Volumn 203, Issue 1, 2013, Pages 217-220

  Larrimore, Katherine E ^a   Barcus, Matthew ^a   Kannan, Latha ^a   Gao, Yang ^b   Zhan, Chang Guo ^c   Brimijoin, Stephen ^b   Mor, Tsafrir ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

^b MAYO GRADUATE SCHOOL   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Addiction; Drug abuse; Plant biotechnology; Protein engineering

Indexed keywords

CARBOXYLESTERASE; CHOLINESTERASE;

BIOCHEMISTRY; COCAINE DEPENDENCE; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; GENE EXPRESSION; GENETIC ENGINEERING; NICOTIANA BENTHAMIANA; NONHUMAN; SPECTROPHOTOMETRY;

AMINO ACID SUBSTITUTION; BUTYRYLCHOLINESTERASE; COCAINE; COCAINE-RELATED DISORDERS; GENETIC VARIATION; HUMANS; HYDROLASES; MUTAGENESIS, SITE-DIRECTED; PLANTS, GENETICALLY MODIFIED; RECOMBINANT PROTEINS; TOBACCO;

NICOTIANA BENTHAMIANA;

EID: 84875808177     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2012.09.004     Document Type: Conference Paper

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