Protection conferred by recombinant Yersinia pestis antigens produced by a rapid and highly scalable plant expression system

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 4, 2006, Pages 861-866

  Santi, Luca ^a   Giritch, Anatoli ^b   Roy, Chad J ^c   Marillonnet, Sylvestre ^b   Klimyuk, Victor ^b   Gleba, Yuri ^b   Webb, Robert ^c   Arntzen, Charles J ^a   Mason, Hugh S ^a  

^a ARIZONA STATE UNIVERSITY   (United States)

^b Biozentrum Halle ^*  (Germany)

^c UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

Plague; Plant biotechnology; Recombinant subunit vaccine; Viral vector

Indexed keywords

F1 V FUSION PROTEIN; RECOMBINANT ANTIGEN; RECOMBINANT F1 ANTIGEN; RECOMBINANT V ANTIGEN; UNCLASSIFIED DRUG; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANTIBIOTIC RESISTANCE; ARTICLE; BIOLOGICAL WARFARE; CONTROLLED STUDY; DRUG SYNTHESIS; GENE EXPRESSION SYSTEM; GUINEA PIG; IMMUNE RESPONSE; NICOTIANA BENTHAMIANA; NONHUMAN; NUCLEOTIDE SEQUENCE; PLAGUE; PLANT BIOTECHNOLOGY; PRIORITY JOURNAL; PROTECTION; TOBACCO; TOBACCO MOSAIC VIRUS; YERSINIA PESTIS;

AEROSOLS; ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BLOTTING, WESTERN; CHROMATOGRAPHY, ION EXCHANGE; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENETIC ENGINEERING; GENETIC VECTORS; GUINEA PIGS; IMMUNOGLOBULIN G; MOLECULAR SEQUENCE DATA; PLANT LEAVES; PLANTS; PORE FORMING CYTOTOXIC PROTEINS; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; RHIZOBIUM; TIME FACTORS; TOBACCO; TOBACCO MOSAIC VIRUS; YERSINIA PESTIS;

ANIMALIA; CAVIA; CAVIA PORCELLUS; NICOTIANA BENTHAMIANA; NICOTIANA TABACUM; TOBACCO MOSAIC VIRUS; YERSINIA PESTIS;

EID: 32244449213     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0510014103     Document Type: Article

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