Effect of polyethylene glycol conjugation on the circulatory stability of plasma-derived human butyrylcholinesterase in mice

Chemico-Biological Interactions

Volumn 203, Issue 1, 2013, Pages 172-176

  Sun, Wei ^a   Luo, Chunyuan ^a,b   Tipparaju, Prasanthi ^a   Doctor, Bhupendra P ^a   Saxena, Ashima ^a  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^b United States Patent and Trademark Office   (United States)

Author keywords

Bioscavenger; Butyrylcholinesterase; Circulatory stability; Mice; Organophosphorus compounds; Polyethylene glycol

Indexed keywords

CHOLINESTERASE; MACROGOL; SCAVENGER; SOMAN;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; CONFERENCE PAPER; CONJUGATION; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; ENZYME ISOLATION; ENZYME STABILITY; HUMAN; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MOUSE; NONHUMAN;

ADULT; ANIMALS; ANTIDOTES; BUTYRYLCHOLINESTERASE; CHEMICAL WARFARE AGENTS; CHOLINESTERASE INHIBITORS; ENZYME STABILITY; HUMANS; MALE; MICE; MICE, INBRED BALB C; POLYETHYLENE GLYCOLS; SOMAN;

ANIMALIA; MUS;

EID: 84875803669     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2012.11.021     Document Type: Conference Paper

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