UV-radiation induced disruption of dry-cavities in human γd-crystallin results in decreased stability and faster unfolding

Scientific Reports

Volumn 3, Issue , 2013, Pages

  Xia, Zhen ^a,b   Yang, Zaixing ^c   Huynh, Tien ^a   King, Jonathan A ^d   Zhou, Ruhong ^a,b,e  

^a IBM T J WATSON RESEARCH CENTER   (United States)

^b MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e Howard Hughes Medical Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CRYGD PROTEIN, HUMAN; GAMMA CRYSTALLIN; KYNURENINE; TRYPTOPHAN; TYROSINE;

ARTICLE; CATARACT; CHEMICAL PHENOMENA; CHEMISTRY; GENETICS; HUMAN; MOLECULAR DYNAMICS; PROTEIN STABILITY; PROTEIN UNFOLDING; RADIATION EXPOSURE; SYNTHESIS; ULTRAVIOLET RADIATION;

CATARACT; GAMMA-CRYSTALLINS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KYNURENINE; MOLECULAR DYNAMICS SIMULATION; PROTEIN STABILITY; PROTEIN UNFOLDING; TRYPTOPHAN; TYROSINE; ULTRAVIOLET RAYS;

EID: 84875793902     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep01560     Document Type: Article

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