Mechanism of the very efficient quenching of tryptophan fluorescence in human γD- and γS-crystallins: The γ-crystallin fold may have evolved to protect tryptophan residues from ultraviolet photodamage

Biochemistry

Volumn 48, Issue 17, 2009, Pages 3708-3716

  Chen, Jiejin ^a   Callis, Patrik R ^b   King, Jonathan ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b MONTANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACKBONE CARBONYL; BOUND WATERS; COVALENT MODIFICATIONS; CRYSTALLIN; ELECTRON TRANSFER; EXCITED-STATE ENERGY; EYE LENS; FAST ELECTRON TRANSFER; LENS PROTEINS; LENS TRANSPARENCY; NATIVE STATE; PHOTO-DAMAGE; PROTEIN COMPONENTS; PROTEIN DAMAGE; PROTEIN FOLDS; TRYPTOPHAN FLUORESCENCE; TRYPTOPHAN RESIDUES; UV RADIATION; UV RESISTANCE;

AMIDES; AMINES; AMINO ACIDS; BIOCHEMISTRY; CHARGE TRANSFER; ELECTRON TRANSITIONS; FEATURE EXTRACTION; FLUORESCENCE; ION EXCHANGE; LENSES; OPTICAL INSTRUMENTS; ORGANIC ACIDS; OXYGEN; PROTEIN FOLDING; ULTRAVIOLET RADIATION;

QUENCHING;

CARBONYL DERIVATIVE; GAMMA CRYSTALLIN; GAMMA D CRYSTALLIN; OXYGEN; TRYPTOPHAN; UNCLASSIFIED DRUG; WATER;

ARTICLE; CONTROLLED STUDY; ELECTRON TRANSPORT; FLUORESCENCE; PHOTOCHEMICAL QUENCHING; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN MODIFICATION; QUANTUM YIELD; RADIOSENSITIVITY; ULTRAVIOLET RADIATION;

CRYSTALLINS; CRYSTALLOGRAPHY, X-RAY; ELECTRON TRANSPORT; EVOLUTION, MOLECULAR; GAMMA-CRYSTALLINS; HUMANS; LENS, CRYSTALLINE; MUTAGENESIS; PROTEIN FOLDING; SPECTROMETRY, FLUORESCENCE; STATIC ELECTRICITY; SUNLIGHT; TRYPTOPHAN; ULTRAVIOLET RAYS;

VERTEBRATA;

EID: 66049087099     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi802177g     Document Type: Article

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