High-resolution X-ray crystal structures of human γD crystallin (1.25 Å) and the R58H mutant (1.15 Å) associated with aculeiform cataract

Journal of Molecular Biology

Volumn 328, Issue 5, 2003, Pages 1137-1147

  Basak, Ajit ^a   Bateman, Orval ^a   Slingsby, Christine ^a   Pande, Ajay ^b   Asherie, Neer ^b   Ogun, Olutayo ^b   Benedek, George B ^b   Pande, Jayanti ^b  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Crystal cataract; Crystallin; Eye lens; Ion pairs; Protein solubility

Indexed keywords

ARGININE; CRYSTALLIN; HISTIDINE; IMMUNOGLOBULIN D; MUTANT PROTEIN; PROTEIN; WATER;

ACULEIFORM CATARACT; ARTICLE; ATOMIC PARTICLE; CATARACT; CRYSTAL STRUCTURE; CRYSTALLIZATION; HUMAN; MASS SPECTROMETRY; MOLECULAR INTERACTION; MUTATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN PROTEIN INTERACTION; WILD TYPE; X RAY;

EID: 0037449145     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(03)00375-9     Document Type: Article

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