Messengers without borders: Mediators of systemic inflammatory response in AKI

Journal of the American Society of Nephrology

Volumn 24, Issue 4, 2013, Pages 529-536

  Ratliff, Brian B ^a   Rabadi, May M ^a   Vasko, Radovan ^a,b   Yasuda, Kaoru ^a,c   Goligorsky, Michael S ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; ENDOTHELIN 1; HIGH MOBILITY GROUP B1 PROTEIN;

ACUTE KIDNEY FAILURE; CHRONIC DISEASE; CYTOKINE PRODUCTION; HUMAN; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY VEIN; NEPHRITIS; NONHUMAN; PRIORITY JOURNAL; RENAL ARTERY; REVIEW; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 84875713622     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2012060633     Document Type: Review

References (76)

1. Chawla LS, Amdur RL, Amodeo S, Kimmel PL, Palant CE: The severity of acute kidney injury predicts progression to chronic kidney disease. Kidney Int 79: 1361-1369, 2011
2. Rabadi MM, Ghaly T, Goligorksy MS, Ratliff BB: HMGB1 in renal ischemic injury. Am J Physiol Renal Physiol 303: F873-F885, 2012
3. Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW: Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 16: 3365-3370, 2005
4. Coca SG, Peixoto AJ, Garg AX, Krumholz HM, Parikh CR: The prognostic importance of a small acute decrement in kidney function in hospitalized patients: A systematic review and meta-analysis. Am J Kidney Dis 50: 712-720, 2007
5. Lassnigg A, Schmidlin D, Mouhieddine M, Bachmann LM, Druml W, Bauer P, Hiesmayr M: Minimal changes of serum creatinine predict prognosis in patients after cardiothoracic surgery: A prospective cohort study. J Am Soc Nephrol 15: 1597-1605, 2004
6. Schwilk B, Wiedeck H, Stein B, Reinelt H, Treiber H, Bothner U: Epidemiology of acute renal failure and outcome of haemodiafiltration in intensive care. Intensive Care Med 23: 1204-1211, 1997
7. Kelly KJ: Distant effects of experimental renal ischemia/reperfusion injury. J Am Soc Nephrol 14: 1549-1558, 2003
8. Li X, Hassoun HT, Santora R, Rabb H: Organ crosstalk: The role of the kidney. Curr Opin Crit Care 15: 481-487, 2009
9. Kinsey GR, Li L, Okusa MD: Inflammation in acute kidney injury. Nephron, Exp Nephrol 109: e102-e107, 2008
10. Chung AC, Lan HY: Chemokines in renal injury. J Am Soc Nephrol 22: 802-809, 2011
11. Ikeda M, Prachasilchai W, Burne-Taney MJ, Rabb H, Yokota-Ikeda N: Ischemic acute tubular necrosis models and drug discovery: A focus on cellular inflammation. Drug Discov Today 11: 364-370, 2006
12. Thurman JM: Triggers of inflammation after renal ischemia/reperfusion. Clin Immunol 123: 7-13, 2007
13. Hochheiser K, Tittel A, Kurts C: Kidney dendritic cells in acute and chronic renal disease. Int J Exp Pathol 92: 193-201, 2011
14. Dong X, Swaminathan S, Bachman LA, Croatt AJ, Nath KA, Griffin MD: Resident dendritic cells are the predominant TNF-secreting cell in early renal ischemia-reperfusion injury. Kidney Int 71: 619-628, 2007
15. Tadagavadi RK, Reeves WB: Renal dendritic cells ameliorate nephrotoxic acute kidney injury. J Am Soc Nephrol 21: 53-63, 2010
16. Matzinger P: The danger model: A renewed sense of self. Science 296: 301-305, 2002
17. Bianchi ME: DAMPs, PAMPs and alarmins: All we need to know about danger. J Leukoc Biol 81: 1-5, 2007
18. Adams V, Lenk K, Linke A, Lenz D, Erbs S, Sandri M, Tarnok A, Gielen S, Emmrich F, Schuler G, Hambrecht R: Increase of circulating endothelial progenitor cells in patients with coronary artery disease after exerciseinduced ischemia. Arterioscler Thromb Vasc Biol 24: 684-690, 2004
19. Taguchi A, Soma T, Tanaka H, Kanda T, Nishimura H, Yoshikawa H, Tsukamoto Y, Iso H, Fujimori Y, Stern DM, Naritomi H, Matsuyama T: Administration of CD34+cells after stroke enhances neurogenesis via angiogenesis in amouse model. J Clin Invest 114: 330-338, 2004
20. Takahashi T, Kalka C, Masuda H, Chen D, Silver M, Kearney M, Magner M, Isner JM, Asahara T: Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization. Nat Med 5: 434-438, 1999
21. Shintani S, Murohara T, Ikeda H, Ueno T, Honma T, Katoh A, Sasaki K, Shimada T,Oike Y, Imaizumi T: Mobilization of endothelial progenitor cells in patients with acute myocardial infarction. Circulation 103: 2776-2779, 2001
22. Patschan D, Patschan S, Gobe GG, Chintala S, Goligorsky MS: Uric acid heralds ischemic tissue injury to mobilize endothelial progenitor cells. J Am Soc Nephrol 18: 1516-1524, 2007
23. Kuo MC, Patschan D, Patschan S, Cohen-Gould L, Park HC, Ni J, Addabbo F, GoligorskyMS: Ischemia-induced exocytosis of Weibel-Palade bodies mobilizes stem cells. J Am Soc Nephrol 19: 2321-2330, 2008
24. Chavakis E, Hain A, Vinci M, Carmona G, Bianchi ME, Vajkoczy P, Zeiher AM, Chavakis T, Dimmeler S: High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells. Circ Res 100: 204-212, 2007
25. Rabadi MM, Kuo MC, Ghaly T, Rabadi SM, Weber M, Goligorsky MS, Ratliff BB: Interaction between uric acid and HMGB1 translocation and release from endothelial cells. Am J Physiol Renal Physiol 302: F730-F741, 2012
26. Meneshian A, Bulkley GB: The physiology of endothelial xanthine oxidase: From urate catabolism to reperfusion injury to inflammatory signal transduction. Microcirculation 9: 161-175, 2002
27. Yasuda K, Vasko R, Hayek P, Ratliff B, Bicer H, Mares J, Maruyama S, Bertuglia S, Mascagni P, Goligorsky MS: Functional consequences of inhibiting exocytosis of Weibel-Palade bodies in acute renal ischemia. Am J Physiol Renal Physiol 302: F713-F721, 2012
28. Mullins GE, Sunden-Cullberg J, Johansson AS, Rouhiainen A, Erlandsson-Harris H, Yang H, Tracey KJ, Rauvala H, Palmblad J, Andersson J, Treutiger CJ: Activation of human umbilical vein endothelial cells leads to relocation and release of high-mobility group box chromosomal protein 1. Scand J Immunol 60: 566-573, 2004
29. Goodwin GH, Sanders C, Johns EW: A new group of chromatin-associated proteins with a high content of acidic and basic amino acids. Eur J Biochem 38: 14-19, 1973
30. Bianchi ME, Beltrame M: Upwardly mobile proteins. Workshop: The role of HMG proteins in chromatin structure, gene expression and neoplasia. EMBO Rep 1: 109-114, 2000
31. Bianchi ME, Beltrame M, Paonessa G: Specific recognition of cruciformDNA by nuclear protein HMG1. Science 243: 1056-1059, 1989
32. Tang D, Kang R, Zeh HJ 3rd, Lotze MT: High-mobility group box 1, oxidative stress, and disease. Antioxid Redox Signal 14: 1315-1335, 2011
33. Ferrari S, Finelli P, Rocchi M, Bianchi ME: The active gene that encodes human high mobility group 1 protein (HMG1) contains introns and maps to chromosome 13. Genomics 35: 367-371, 1996
34. Rauvala H, Merenmies J, Pihlaskari R, Korkolainen M, Huhtala ML, Panula P: The adhesive and neurite-promoting molecule p30: Analysis of the amino-terminal sequence and production of antipeptide antibodies that detect p30 at the surface of neuroblastoma cells and of brain neurons. J Cell Biol 107: 2293-2305, 1988
35. Wen L, Huang JK, Johnson BH, Reeck GR: A human placental cDNA clone that encodes nonhistone chromosomal protein HMG-1. Nucleic Acids Res 17: 1197-1214, 1989
36. Paonessa G, Frank R, Cortese R: Nucleotide sequence of rat liver HMG1 cDNA. Nucleic Acids Res 15: 9077, 1987
37. Erlandsson Harris H, Andersson U: Minireview: The nuclear protein HMGB1 as a proinflammatory mediator. Eur J Immunol 34: 1503-1512, 2004
38. Hayakawa K, Arai K, Lo EH: Role of ERK map kinase and CRM1 in IL-1beta-stimulated release of HMGB1 from cortical astrocytes. Glia 58: 1007-1015, 2010
39. Oh YJ, Youn JH, Ji Y, Lee SE, Lim KJ, Choi JE, Shin JS: HMGB1 is phosphorylated by classical protein kinase C and is secreted by a calcium-dependent mechanism. J Immunol 182: 5800-5809, 2009
40. Zhang X, Wheeler D, Tang Y, Guo L, Shapiro RA, Ribar TJ, Means AR, Billiar TR, Angus DC, Rosengart MR: Calcium/calmodulindependent protein kinase (CaMK) IV mediates nucleocytoplasmic shuttling and release of HMGB1 during lipopolysaccharide stimulation of macrophages. J Immunol 181: 5015-5023, 2008
41. Bonaldi T, Talamo F, Scaffidi P, Ferrera D, Porto A, Bachi A, Rubartelli A, Agresti A, Bianchi ME: Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion.EMBOJ 22: 5551-5560, 2003
42. Youn JH, Shin JS: Nucleocytoplasmic shuttling of HMGB1 is regulated by phosphorylation that redirects it toward secretion. J Immunol 177: 7889-7897, 2006
43. Evankovich J, Cho SW, Zhang R, Cardinal J, Dhupar R, Zhang L, Klune JR, Zlotnicki J, Billiar T, Tsung A: High mobility group box 1 release from hepatocytes during ischemia and reperfusion injury is mediated by decreased histone deacetylase activity. J Biol Chem 285: 39888-39897, 2010
44. Stros M, Reich J, Kolíbalová A: Calcium binding to HMG1 protein induces DNA looping by theHMG-box domains. FEBS Lett 344: 201-206, 1994
45. Stros M, Bernués J, Querol E: Calcium modulates the binding of high-mobility-group protein 1 toDNA. BiochemInt 21: 891-899, 1990
46. Polianichko AM, Chikhirzhina EV, Andrushchenko VV, Kostyleva EI, Wieser H, Vorob'ev VI: [The effect of Ca2+ ions onDNA compaction in the complex with non-histone chromosomal protein HMGB1]. Mol Biol (Mosk) 38: 701-712, 2004
47. Gardella S,AndreiC, Ferrera D, Lotti LV, Torrisi MR, Bianchi ME, Rubartelli A: The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway. EMBO Rep 3: 995-1001, 2002
48. Park JS, Arcaroli J, Yum HK, Yang H, Wang H, Yang KY, Choe KH, Strassheim D, Pitts TM, Tracey KJ, Abraham E: Activation of gene expression in human neutrophils by high mobility group box 1 protein. Am J Physiol Cell Physiol 284: C870-C879, 2003
49. Yu M, Wang H, Ding A, Golenbock DT, Latz E, Czura CJ, Fenton MJ, Tracey KJ, Yang H: HMGB1 signals through toll-like receptor (TLR) 4 and TLR2. Shock 26: 174-179, 2006
50. Park JS, Gamboni-Robertson F, He Q, Svetkauskaite D, Kim JY, Strassheim D, Sohn JW, Yamada S, Maruyama I, Banerjee A, Ishizaka A, Abraham E: High mobility group box 1 protein interacts with multiple Toll-like receptors. Am J Physiol Cell Physiol 290: C917-C924, 2006
51. Kokkola R, Andersson A, Mullins G, Ostberg T, Treutiger CJ, Arnold B, Nawroth P, Andersson U, Harris RA, Harris HE: RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages. Scand J Immunol 61: 1-9, 2005
52. Park JS, Svetkauskaite D, He Q, Kim JY, Strassheim D, Ishizaka A, Abraham E: Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein.J Biol Chem 279: 7370-7377, 2004
53. Kang R, Tang D, Schapiro NE, Livesey KM, Farkas A, Loughran P, Bierhaus A, LotzeMT, Zeh HJ: The receptor for advanced glycation end products (RAGE) sustains autophagy and limits apoptosis, promoting pancreatic tumor cell survival. Cell Death Differ 17: 666-676, 2010
54. ElMezayen R, El Gazzar M, Seeds MC, McCall CE, Dreskin SC, Nicolls MR: Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin. Immunol Lett 111: 36-44, 2007
55. Chen GY, Tang J, Zheng P, Liu Y: CD24 and Siglec-10 selectively repress tissue damageinduced immune responses. Science 323: 1722-1725, 2009
56. Abraham E, Arcaroli J, Carmody A, Wang H, Tracey KJ: HMG-1 as a mediator of acute lung inflammation. J Immunol 165: 2950-2954, 2000
57. Wang H, Bloom O, Zhang M, Vishnubhakat JM, Ombrellino M, Che J, Frazier A, Yang H, Ivanova S, Borovikova L, Manogue KR, Faist E, Abraham E, Andersson J, Andersson U, Molina PE, Abumrad NN, Sama A, Tracey KJ: HMG-1 as a late mediator of endotoxin lethality in mice. Science 285: 248-251, 1999
58. Li J, Gong Q, Zhong S, Wang L, Guo H, Xiang Y, Ichim TE, Wang CY, Chen S, Gong F, Chen G: Neutralization of the extracellular HMGB1 released by ischaemic damaged renal cells protects against renal ischaemia-reperfusion injury. Nephrol Dial Transplant 26: 469-478, 2011
59. Palumbo R, Sampaolesi M, De Marchis F, Tonlorenzi R, Colombetti S, Mondino A, Cossu G, Bianchi ME: Extracellular HMGB1, a signal of tissue damage, induces mesoangioblast migration and proliferation. J Cell Biol 164: 441-449, 2004
60. Wu H, Ma J, Wang P, Corpuz TM, Panchapakesan U, Wyburn KR, Chadban SJ: HMGB1 contributes to kidney ischemia reperfusion injury. J Am Soc Nephrol 21: 1878-1890, 2010
61. Chung KY, Park JJ, Kim YS: The role of highmobility group box-1 in renal ischemia and reperfusion injury and the effect of ethyl pyruvate. Transplant Proc 40: 2136-2138, 2008
62. Chen J, John R, Richardson JA, Shelton JM, Zhou XJ, Wang Y, Wu QQ, Hartono JR, Winterberg PD, Lu CY: Toll-like receptor 4 regulates early endothelial activation during ischemic acute kidney injury. Kidney Int 79: 288-299, 2011
63. Lu CY, Hartono J, Senitko M, Chen J: The inflammatory response to ischemic acute kidney injury: A result of the 'right stuff' in the 'wrong place'? Curr Opin Nephrol Hypertens 16: 83-89, 2007
64. Andersson U, Wang H, Palmblad K, Aveberger AC, Bloom O, Erlandsson-Harris H, Janson A, Kokkola R, Zhang M, Yang H, Tracey KJ: High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med 192: 565-570, 2000
65. Luan ZG, Zhang H, Yang PT, Ma XC, Zhang C, Guo RX: HMGB1 activates nuclear factor-kB signaling by RAGE and increases the production of TNF-a in human umbilical vein endothelial cells. Immunobiology 215: 956-962, 2010
66. Zhong TY, Tang J, Liu YW, Li ZJ, Chen DY, Zhao MZ, Wang W, Liu JH, Jiang Y: High mobility group box-1 stimulates proinflammatory cytokine production in endothelial cells via MAP kinases [Article in Chinese]. Nan Fang Yi Ke Da Xue Xue Bao 29: 1517-1520, 2009
67. Treutiger CJ, Mullins GE, Johansson AS, Rouhiainen A, Rauvala HM, Erlandsson-Harris H, Andersson U, Yang H, Tracey KJ, Andersson J, Palmblad JE: High mobility group 1 B-box mediates activation of human endothelium. J Intern Med 254: 375-385, 2003
68. Tamai K, Yamazaki T, Chino T, Ishii M, Otsuru S, Kikuchi Y, Iinuma S, Saga K, Nimura K, Shimbo T, Umegaki N, Katayama I, Miyazaki J, Takeda J, McGrath JA, Uitto J, Kaneda Y: PDGFRalpha-positive cells inbonemarroware mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia. Proc Natl Acad Sci U S A 108: 6609-6614, 2011
69. Kohno T, Anzai T, Naito K, Miyasho T, Okamoto M, Yokota H, Yamada S, Maekawa Y, Takahashi T, Yoshikawa T, Ishizaka A, Ogawa S: Role of high-mobility group box 1 protein in post-infarction healing process and left ventricular remodelling. Cardiovasc Res 81: 565-573, 2009
70. Limana F, Germani A, Zacheo A, Kajstura J, Di Carlo A, Borsellino G, Leoni O, Palumbo R, Battistini L, Rastaldo R, Müller S, Pompilio G, Anversa P, Bianchi ME, Capogrossi MC: Exogenous high-mobility group box 1 protein induces myocardial regeneration after infarction via enhanced cardiac C-kit+ cell proliferation and differentiation. Circ Res 97: e73-e83, 2005
71. Ranzato E, Patrone M, Pedrazzi M, Burlando B: Hmgb1 promotes wound healing of 3T3 mouse fibroblasts via RAGE-dependent ERK1/2 activation. Cell BiochemBiophys 57: 9-17, 2010
72. Ranzato E, Patrone M, Pedrazzi M, Burlando B: HMGb1 promotes scratch wound closure of HaCaT keratinocytes via ERK1/2 activation. Mol Cell Biochem 332: 199-205, 2009
73. Sachdev U, Cui X, Hong G, Namkoong S, Karlsson JM, Baty CJ, Tzeng E: High mobility group box 1 promotes endothelial cell angiogenic behavior in vitro and improves muscle perfusion in vivo in response to ischemic injury. J Vasc Surg 55: 180-191, 2012
74. Biscetti F, Straface G, De Cristofaro R, Lancellotti S, Rizzo P, Arena V, Stigliano E, Pecorini G, Egashira K, De Angelis G, Ghirlanda G, Flex A: High-mobility group box-1 protein promotes angiogenesis after peripheral ischemia in diabetic mice through a VEGF-dependent mechanism. Diabetes 59: 1496-1505, 2010
75. Mitola S, Belleri M, Urbinati C, Coltrini D, Sparatore B, Pedrazzi M, Melloni E, Presta M: Cutting edge: extracellular high mobility group box-1 protein is a proangiogenic cytokine. J Immunol 176: 12-15, 2006
76. Wake H, Mori S, Liu K, Takahashi HK, Nishibori M: High mobility group box 1 complexed with heparin induced angiogenesis in a matrigel plug assay. Acta Med Okayama 63: 249-262, 2009