Ischemic acute tubular necrosis models and drug discovery: a focus on cellular inflammation

Drug Discovery Today

Volumn 11, Issue 7-8, 2006, Pages 364-370

  Ikeda, Masahiro ^a   Prachasilchai, Worapat ^a   Burne Taney, Melissa J ^b   Rabb, Hamid ^b   Yokota Ikeda, Naoko ^c  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MIYAZAKI PREFECTURAL MIYAZAKI HOSPITAL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ABATACEPT; AMINO ACID; AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBODY; ANTIINFECTIVE AGENT; ATORVASTATIN; B7 1 ANTIBODY; B7 2 ANTIBODY; BIMOSIAMOSE; CALCINEURIN INHIBITOR; CASEIN KINASE II; CERIVASTATIN; CHEMOKINE; CISPLATIN; CYTOKINE; FINGOLIMOD; GENTAMICIN; GLYCEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INOSINATE DEHYDROGENASE INHIBITOR; INTERLEUKIN 10; INTERLEUKIN 12 ANTIBODY; INTERLEUKIN 6 ANTIBODY; METHIONINE; MONOCLONAL ANTIBODY; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PRAVASTATIN; PROTEIN KINASE; RANTES; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACUTE KIDNEY FAILURE; ACUTE KIDNEY TUBULE NECROSIS; ANTIGEN PRESENTING CELL; B LYMPHOCYTE; CAUSE OF DEATH; CELL CULTURE; CELL FUNCTION; CELL INTERACTION; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG IDENTIFICATION; DRUG TARGETING; GLOMERULONEPHRITIS; HOSPITAL PATIENT; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INFLAMMATORY CELL; INNATE IMMUNITY; ISCHEMIC ACUTE TUBULAR NECROSIS; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY ISCHEMIA; KIDNEY PERFUSION; KIDNEY TUBULE CELL; MORBIDITY; MORTALITY; NEPHRITIS; NEPHROTOXICITY; NONHUMAN; PATHOPHYSIOLOGY; REVIEW; SAFETY; T LYMPHOCYTE; TH1 CELL;

ANIMALS; ANTI-INFLAMMATORY AGENTS; B-LYMPHOCYTES; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INFLAMMATION; ISCHEMIA; KIDNEY; KIDNEY TUBULAR NECROSIS, ACUTE; MYCOPHENOLIC ACID; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; T-LYMPHOCYTES;

EID: 33645862574     PISSN: 13596446     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drudis.2006.02.010     Document Type: Review

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