Upwardly mobile proteins - Workshop: The role of HMG proteins in chromatin structure, gene expression and neoplasia

EMBO Reports

Volumn 1, Issue 2, 2000, Pages 109-114

  Blanchi, Marco E ^a   Beltrame, Monica ^b  

^a San Raffade Research Institute   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HIGH MOBILITY GROUP PROTEIN;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CHROMATIN; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METABOLISM; MOUSE; OBESITY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN CONFORMATION; PROTEIN MOTIF; PROTEIN TERTIARY STRUCTURE; TRANSGENIC MOUSE;

AMINO ACID MOTIFS; ANIMALS; CHROMATIN; DNA; HIGH MOBILITY GROUP PROTEINS; HUMANS; MICE; MICE, TRANSGENIC; MODELS, MOLECULAR; OBESITY; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; TRANSCRIPTION, GENETIC;

EID: 0034252817     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1093/embo-reports/kvd030     Document Type: Article

References (14)

1. Anand, A. and Chada, K. (2000) In vivo modulation of Hmgic reduces obesity. Nature Genet., 24, 377-380.
2. Arlotta, P., Tai, A.K., Manfioletti, G., Clifford, C., Jay, G. and Ono, S.J. (2000) Transgenic mice expressing a truncated form of the high mobility group I-C protein develop adiposity and an abnormally high prevalence of lipomas. J. Biol. Chem., 275, 14394-14400.
3. Banks, G.C., Li, Y. and Reeves, R. (2000) Differential in vivo modifications of the HMGI(Y) nonhistone chromatin proteins modulate nucleosome and DMA interactions. Biochemistry, 19, 8333-8346.
4. Battista, S., Fidanza, V., Fedele, M., Klein-Szanto, A.J., Outwater, E., Brunner, H., Santoro, M., Croce, CM. and Fusco, A. (1999) The expression of a truncated HMGI-C gene induces gigantism associated with lipomatosis. Cancer Res., 59, 4793-4797.
5. Bergel, M., Herrera, J.E., Thatcher, B.J., Prymakowska-Bosak, M., Vassilev, A., Nakatani, Y., Martin, B. and Bustin, M. (2000) Acetylation of novel sites in the nucleosomal binding domain of chromosomal protein HMG-14 by p300 alters its interaction with nucleosomes. J. Biol. Chem., 275, 11514-11520.
6. Bustin, M. (1999) Regulation of DNA-dependent activities by the functional motifs of the high-mobility-group chromosomal proteins. Mol. Cell. Biol., 19, 5237-5246.
7. Calogero, S., Grassi, F., Aguzzi, A., Voigtländer, T., Ferrier, P., Ferrari, S. and Bianchi, M.E. (1999) The lack of chromosomal protein HMG1 does not disrupt cell growth, but causes lethal hypoglycaemia in newborn mice. Nature Genet., 22, 276-280.
8. Ellwood, K.B., Yen, Y.M., Johnson, R.C. and Carey, M. (2000) Mechanism for specificity by HMG-1 in enhanceosome assembly. Mol. Cell. Biol., 20, 4359-4370.
9. He, Q., Liang, C.H., and Lippard, S.J. (2000) Steroid hormones induce HMG1 overexpression and sensitize breast cancer cells to cisplatin and carboplatin. Proc. Natl Acad. Sci. USA, 97, 5768-5772.
10. Peirano, R.I., Goerich, D.E., Riethmacher, D. and Wegner, M. (2000) Protein zero gene expression is regulated by the glial transcription factor Sox10. Mol. Cell. Biol, 20, 3198-3209.
11. Reeves, R., Leonard, W.J. and Nissen, M.S. (2000) Binding of HMG-I(Y) imparts architectural specificity to a positioned nucleosome on the promoter of the human interleukin-2 receptor a gene. Mol. Cell. Biol., 20, 4666-4679.
12. Thomson, S., Clayton, A.L., Hazzalin, C.A., Rose, S., Barratt, M.J. and Mahadevan, L.C. (1999) The nucleosomal response associated with immediate-early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase. EMBO J., 18, 4779-4793.
13. Wegner, M. (1999) From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res., 27, 1409-1420.
14. Yie, J., Senger, K. and Thanos, D. (1999) Mechanism by which the IFN-β enhanceosome activates transcription. Proc. Natl Acad. Sci. USA, 96, 13108-13113.