CLL Cells Respond to B-Cell Receptor Stimulation with a MicroRNA/mRNA Signature Associated with MYC Activation and Cell Cycle Progression

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Pede, Valerie ^a   Rombout, Ans ^a   Vermeire, Jolien ^a   Naessens, Evelien ^a   Mestdagh, Pieter ^a   Robberecht, Nore ^a   Vanderstraeten, Hanne ^a   Van Roy, Nadine ^a   Vandesompele, Jo ^a   Speleman, Frank ^a   Philippé, Jan ^a   Verhasselt, Bruno ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

B LYMPHOCYTE RECEPTOR; DUAL SPECIFICITY PHOSPHATASE 2; EARLY GROWTH RESPONSE FACTOR 1; IMMUNOGLOBULIN HEAVY CHAIN; MESSENGER RNA; MICRORNA; MICRORNA 132; MICRORNA 146A; MICRORNA 155; MICRORNA 212; MYC PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN FOS; PROTIEN NFAT5; TRANSCRIPTION FACTOR ELK 1; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ARTICLE; B LYMPHOCYTE ACTIVATION; CANCER CELL; CARCINOGENESIS; CELL ACTIVATION; CELL CYCLE PROGRESSION; CELL PROLIFERATION; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE CLUSTER; GENE EXPRESSION REGULATION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HYBRIDIZATION; IMMUNOGLOBULIN HEAVY CHAIN GENE; IN VITRO STUDY; INTRACELLULAR SIGNALING; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION;

ANTIBODIES, ANTI-IDIOTYPIC; B-LYMPHOCYTES; CELL CYCLE; CELLS, CULTURED; GENE EXPRESSION REGULATION, LEUKEMIC; GENOME-WIDE ASSOCIATION STUDY; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; LYMPHOCYTE ACTIVATION; MICRORNAS; MULTIGENE FAMILY; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTORS, ANTIGEN, B-CELL; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 84875678454     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0060275     Document Type: Article

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