BCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgVH unmutated chronic lymphocytic leukemia (CLL) cells

Blood

Volumn 112, Issue 3, 2008, Pages 782-792

  Guarini, Anna ^a   Chiaretti, Sabina ^a   Tavolaro, Simona ^a   Maggio, Roberta ^a   Peragine, Nadia ^a   Citarella, Franca ^a   Ricciardi, Maria Rosaria ^a   Santangelo, Simona ^a   Mahnelli, Marilisa ^a   De Propris, Maria Stefania ^a   Messina, Monica ^a   Mauro, Francesca Romana ^a   Del Giudice, Ilaria ^a   Foà, Robert ^a,b  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b Division of Hematology   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BREAKPOINT CLUSTER REGION PROTEIN; IMMUNOGLOBULIN M; IMMUNOGLOBULIN HEAVY CHAIN; LYMPHOCYTE ANTIGEN RECEPTOR;

ADULT; AGED; APOPTOSIS; ARTICLE; CELL CYCLE REGULATION; CELL PROLIFERATION; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOGLOBULIN VARIABLE REGION; LEUKEMIA CELL; MALE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; B CELL LEUKEMIA; CELL CYCLE; DISEASE COURSE; GENE EXPRESSION REGULATION; IMMUNOLOGY; METABOLISM; MIDDLE AGED; MUTATION; PATHOLOGY;

ADULT; AGED; AGED, 80 AND OVER; APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN M; IMMUNOGLOBULIN VARIABLE REGION; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MALE; MIDDLE AGED; MUTATION; RECEPTORS, ANTIGEN, B-CELL; SIGNAL TRANSDUCTION;

EID: 50949128066     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2007-12-127688     Document Type: Article

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