Two 4N Cell-Cycle Arrests Contribute to Cisplatin-Resistance

PLoS ONE

Volumn 8, Issue 4, 2013, Pages

  Shen, Hong ^a   Perez, Ricardo E ^a   Davaadelger, Batzaya ^a   Maki, Carl G ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CYCLE PROTEIN; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CISPLATIN; CYCLIN A; CYCLIN B; PROTEIN CDC2; PROTEIN P21; PROTEIN P53; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; BIOACCUMULATION; CANCER RESISTANCE; CELL CLONE; CELL CYCLE ARREST; CELL EXPANSION; CELL ISOLATION; CONTROLLED STUDY; ENZYME ACTIVITY; G1 PHASE CELL CYCLE CHECKPOINT; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPRODUCIBILITY; S PHASE CELL CYCLE CHECKPOINT; SENSITIVITY ANALYSIS; TARGET CELL DESTRUCTION; TETRAPLOIDY;

ANTINEOPLASTIC AGENTS; CISPLATIN; CYCLIN A; CYCLIN B; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; DRUG RESISTANCE, NEOPLASM; G1 PHASE; G2 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HUMANS; RNA, SMALL INTERFERING; STAUROSPORINE; TETRAPLOIDY; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84875664116     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059848     Document Type: Article

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