Chondrogenesis in a cell-polymer-bioreactor system

Experimental Cell Research

Volumn 240, Issue 1, 1998, Pages 58-65

  Freed, L E ^a   Hollander, A P ^b   Martin, I ^a   Barry, J R ^a   Langer, R ^a   Vunjak Novakovic, G ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Cartilage; Chondrocyte; Collagen type II; Proteoglycan; Scaffold; Tissue engineering

Indexed keywords

COLLAGEN TYPE 2; GLYCOSAMINOGLYCAN; POLYMER; PROLINE; SULFATE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOREACTOR; CARTILAGE; CARTILAGE CELL; CATTLE; CELL CONTACT; CELL DENSITY; CHONDROGENESIS; CONTROLLED STUDY; LIMB DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL;

ANIMALIA; BOS TAURUS; BOVINAE;

EID: 0031869101     PISSN: 00144827     EISSN: None     Source Type: Journal    
DOI: 10.1006/excr.1998.4010     Document Type: Article

References (29)

1. Buckwalter, J. A., and Mankin, H. J. (1997). Articular cartilage, part I: Tissue design and chondrocyte-matrix interactions. J. Bone Joint Surg. 79A, 600-611.
2. Buckwalter, J. A., and Mankin, H. J. (1997). Articular cartilage, part II: Degeneration and osteoarthrosis, repair, regeneration, and transplantation. J. Bone Joint Surg. 79A, 612-632.
3. Newman, A. P. (1998). Articular cartilage repair. Am J. Sports Med. 26(2), March-April issue
4. Freed, L. E., Langer, R., Martin, I., Pellis, N., and Vunjak-Novakovic, G. (1997). Tissue engineering of cartilage in space Proc. Nat. Acad. Sci. USA 94(25), 13885-13890.
5. Buschmann, M. D., Gluzband, Y. A., Grodzinsky, A. J., Kimura, J. H., and Hunziker, E. B. (1992). Chondrocytes in agarose culture synthesize a mechanically functional extracellular matrix J. Orthop. Res. 10, 745-752.
6. Freed, L. E., Marquis, J. C., Nohria, A., Mikos, A. G., Emmanual, J., and Langer, R. (1993). Neocartilage formation in vitro and in vivo using cells cultured on synthetic biodegradable polymers. J. Biomed. Mater. Res. 27, 11-23.
7. Freed, L. E., Vunjak, G., Biron, R. J., Eagles, D., Lesnoy D., Barlow, S. K., and Langer, R. (1994). Biodegradable polymer scaffolds for tissue engineering. Bio/Technology 12, 689-693.
8. Freed, L. E., and Vunjak-Novakovic, G. (1997). in "Principles of Tissue Engineering" (R. P. Lanza, W. Chick, R. Langer, Eds.), pp. 151-165, Academic Press, Austin.
9. Freed, L. E., and Vunjak-Novakovic, G. (1997). Microgravity tissue engineering. In Vitro Cell. Dev. Biol. 33, 381-385.
10. Sah, R. L. Y., Kim, Y. J., Doong, J. Y. H., Grodzinsky, A. J., Plaas, A. H. K., and Sandy, J. D. (1989). Biosynthetic response of cartilage explants to dynamic compression. J Orthop. Res. 7, 619-636.
11. Kim, Y. J., Sah, R. L., Doong, J. Y. H., and Grodzinsky, A. J. (1988). Fluorometric assay of DNA in cartilage explants using Hoechst 33258. Anal. Biochem. 174, 168-176.
12. Farndale, R. W., Buttle, D. J., and Barrett, A. J. (1986). Improved quantitation and discrimination of sulphated glycosaminoglycans by the use of dimethylmethylene blue. Biochim. Biophys. Acta 883, 173-177.
13. Hollander, A. P., Heathfield, T. F., Webber, C., Iwata, Y., Bourne, R., Rorabeck, C., and Poole, A. R. (1994). Increased damage to type II collagen in osteoarthritic articular cartilage detected by a new immunoassay. J. Clin. Invest. 93, 1722-1732.
14. Woessner, J. F. (1961). The determination of hydroxyproline in tissue and protein samples containing small proportions of this imino acid. Archiv. Biochem. Biophys. 93, 440-447.
15. Sah, R. L. Y., Kim, Y. J., Doong, J. Y. H., Grodzinsky, A. J., Plaas, A. H. K., and Sandy, J. D. (1991). Effects of compression on the loss of newly synthesized proteoglycans and proteins from cartilage explants. Arch. Biochem. Biophys. 286, 20-29.
16. Kuettner, K. E., Memoli, V. A., Pauli, B. U., Wrobel, N. C., Eugene, J. M., Thonar, A., and Daniel, J. C. (1982). Synthesis of cartilage matrix by mammalian chondrocytes in vitro. II. Maintenance of collagen and proteoglycan phenotype. J. Cell Biol. 93, 751-757.
17. Osborn, K. D., Trippel, S. B., and Mankin, H. J. (1989). Growth factor stimulation of adult articular cartilage. J. Orthop. Res. 7, 35-42.
18. MacGinitie, L. A., Gluzband, Y. A., and Grodzinsky, A. J. (1994). Electric field stimulation can increase protein synthesis in articular cartilage expiants. J. Orthop. Res. 12, 151-160.
19. Gunter, J. P., Clark, C. P., and Friedman, R. M. (1997). Internal stabilization of autogenous rib cartilage grafts in rhinoplasty: A barrier to cartilage warping. Plast. Reconstr. Surg. 100, 161-169.
20. Tachetti, C., Tavella, S., Dozin, B., Quarto, R., Robino, G., and Cancedda, R. (1992). Cell condensation in chondrogenic differentiation. Exp. Cell Res. 200, 26-33.
21. Gurdon, J. B. (1988). A community effect in animal development. Nature 336, 772-774.
22. Kulyk, W. M., Coelho, C. N. D., and Kosher, R. A. (1991). Type IX collagen gene expression during limb cartilage differentiation. Matrix 11, 282-288.
23. Treilleux, I., Mallein-Gerin, F., Le Guellec, D., and Herbage, D. (1992). Localization of the expression of type I, II, II collagen and aggregan core protein genes in developing human articular cartilage. Matrix 12, 221-232.
24. Gerstenfeld, L. C., and Landis, W. J. (1991). Gene expression and extracellular matrix ultrastructure of a mineralizing chondrocyte cell culture system. J. Cell. Biol. 112, 501-513.
25. Solursh, M., Reiter, R. S., Ahrens, P. B., and Vertel, B. M. (1981). Stage and position-related changes in chondrogenic response of chick embryonic wing mesenchyme to treatment with dibutyryl cyclic AMP. Dev. Biol. 83, 9-19.
26. Kulyk, W. M., Rodgers, B. J., Greer, K., and Kosher R. A. (1989). Promotion of embryonic chick limb cartilage differentiation by transforming growth factor β. Dev. Biol. 135, 424-430.
27. Coelho, C. N. D., and Kosher, R. A. (1991). Gap junctional communication during limb cartilage differentiation, Dev. Biol. 144, 47-53.
28. Zanetti, N. C., and Solursh, M. (1984). Induction of chondrogenesis in limb mesenchymal cultures by disruption of the actin cytoskeleton. J. Cell. Biol. 99, 115-123.
29. Hauselmann, H. J., Fernandes, R. J., Mok, S. S., Schmid, T. M., Block, J. A., Aydelotte, M. B., Kuettner, K. E., and Thonar, E. J. M. (1994). Phenotypic stability of bovine articular chondrocytes after long-term culture in alginate beads. J. Cell Sci. 107, 17-27.