Twin screw wet granulation: Influence of formulation parameters on granule properties and growth behavior

Powder Technology

Volumn 238, Issue , 2013, Pages 108-115

  El Hagrasy, A S ^a   Hennenkamp, J R ^b   Burke, M D ^c   Cartwright, J J ^c   Litster, J D ^a,d  

^a PURDUE UNIVERSITY   (United States)

^b GLAXOSMITHKLINE   (United States)

^c GLAXOSMITHKLINE   (United Kingdom)

^d PURDUE UNIVERSITY   (United States)

Author keywords

Dry versus liquid binder; Excipient particle size; Granulating liquid distribution; Granule growth; Liquid content; Twin screw granulation

Indexed keywords

EXCIPIENT PARTICLES; GRANULATING LIQUIDS; LIQUID BINDERS; LIQUID CONTENTS; TWIN SCREW;

BINDERS; GRANULATION; GRANULATORS; LIQUIDS; PARTICLE SIZE; RESIDENCE TIME DISTRIBUTION; SUGARS;

PARTICLES (PARTICULATE MATTER);

CROSCARMELLOSE SODIUM; HYDROXYPROPYLMETHYLCELLULOSE; LACTOSE; MICROCRYSTALLINE CELLULOSE;

ARTICLE; DRUG GRANULATION; DRUG GRANULE; LIQUID; PARTICLE SIZE; POROSITY; SOLID; TWIN SCREW WET GRANULATION;

EID: 84875634369     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2012.04.035     Document Type: Article

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