-
1
-
-
77957037030
-
Islets and their antioxidant defense
-
Acharya JD, Ghaskadbi SS. 2010. Islets and their antioxidant defense. Islets 2: 225-235.
-
(2010)
Islets
, vol.2
, pp. 225-235
-
-
Acharya, J.D.1
Ghaskadbi, S.S.2
-
3
-
-
33749344947
-
ERK1/2 control phosphorylation and protein level of cAMP-responsive element-binding protein: A key role in glucose-mediated pancreatic beta-cell survival
-
Costes S, Broca C, Bertrand G, Lajoix AD, Bataille D, Bockaert J, Dalle S. 2006. ERK1/2 control phosphorylation and protein level of cAMP-responsive element-binding protein: A key role in glucose-mediated pancreatic beta-cell survival. Diabetes 55: 2220-2230.
-
(2006)
Diabetes
, vol.55
, pp. 2220-2230
-
-
Costes, S.1
Broca, C.2
Bertrand, G.3
Lajoix, A.D.4
Bataille, D.5
Bockaert, J.6
Dalle, S.7
-
4
-
-
23944500772
-
C2-symmetrical thiodigalactoside bis-benzamido derivatives as high-affinity inhibitors of galectin-3: Efficient lectin inhibition through double arginine-arene interactions
-
Cumpstey I, Sundin A, Leffler H, Nilsson UJ. 2005. C2-symmetrical thiodigalactoside bis-benzamido derivatives as high-affinity inhibitors of galectin-3: Efficient lectin inhibition through double arginine-arene interactions. Angew Chem Int Ed 44: 5110-5112.
-
(2005)
Angew Chem Int Ed
, vol.44
, pp. 5110-5112
-
-
Cumpstey, I.1
Sundin, A.2
Leffler, H.3
Nilsson, U.J.4
-
6
-
-
33644747390
-
Mechanisms of beta cell death in type 2 diabetes
-
Donath MY, Ehses JA, Maedler K, Schumann DM, Ellingsgaard H, Eppler E, Reinecke M. 2005. Mechanisms of beta cell death in type 2 diabetes. Diabetes 54: S108-S113.
-
(2005)
Diabetes
, vol.54
-
-
Donath, M.Y.1
Ehses, J.A.2
Maedler, K.3
Schumann, D.M.4
Ellingsgaard, H.5
Eppler, E.6
Reinecke, M.7
-
7
-
-
43549093332
-
Cytokines and beta-cell biology: From concept to clinical translation
-
Donath MY, Storling J, Berchtold LA, Billestrup N, Mandrup-Poulsen T. 2008. Cytokines and beta-cell biology: From concept to clinical translation. Endocr Rev 29: 334-350.
-
(2008)
Endocr Rev
, vol.29
, pp. 334-350
-
-
Donath, M.Y.1
Storling, J.2
Berchtold, L.A.3
Billestrup, N.4
Mandrup-Poulsen, T.5
-
9
-
-
20444366717
-
Galectin-3 and soluble fibrinogen act in concert to modulate neutrophil activation and survival: Involvement of alternative MAPK pathways
-
Fernandez GC, Ilarregui JM, Rubel CJ, Toscano MA, Gómez SA, Beigier Bompadre M, Isturiz MA, Rabinovich GA, Palermo MS. 2005. Galectin-3 and soluble fibrinogen act in concert to modulate neutrophil activation and survival: Involvement of alternative MAPK pathways. Glycobiology 15: 519-527.
-
(2005)
Glycobiology
, vol.15
, pp. 519-527
-
-
Fernandez, G.C.1
Ilarregui, J.M.2
Rubel, C.J.3
Toscano, M.A.4
Gómez, S.A.5
Beigier Bompadre, M.6
Isturiz, M.A.7
Rabinovich, G.A.8
Palermo, M.S.9
-
10
-
-
0345734273
-
CD29 and CD7 mediate galectin-3-induced type II T-cell apoptosis
-
Fukumori T, Takenaka Y, Yoshii T, Kim HR, Hogan V, Inohara H, Kagawa S, Raz A. 2003. CD29 and CD7 mediate galectin-3-induced type II T-cell apoptosis. Cancer Res 63: 8302-8311.
-
(2003)
Cancer Res
, vol.63
, pp. 8302-8311
-
-
Fukumori, T.1
Takenaka, Y.2
Yoshii, T.3
Kim, H.R.4
Hogan, V.5
Inohara, H.6
Kagawa, S.7
Raz, A.8
-
11
-
-
2442684458
-
Endogenous galectin-3 determines the routing of CD95 apoptotic signaling pathways
-
Fukumori T, Takenaka Y, Oka N, Yoshii T, Hogan V, Inohara H, Kanayama HO, Kim HR, Raz A. 2004. Endogenous galectin-3 determines the routing of CD95 apoptotic signaling pathways. Cancer Res 64: 3376-3379.
-
(2004)
Cancer Res
, vol.64
, pp. 3376-3379
-
-
Fukumori, T.1
Takenaka, Y.2
Oka, N.3
Yoshii, T.4
Hogan, V.5
Inohara, H.6
Kanayama, H.O.7
Kim, H.R.8
Raz, A.9
-
12
-
-
33645507043
-
Galectin-3 regulates mitochondrial stability and antiapoptotic function in response to anticancer drug in prostate cancer
-
Fukumori T, Oka N, Takenaka Y, Nangia-Makker P, Elsamman E, Kasai T, Shono M, Kanayama H, Ellerhorst J, Lotan R, Raz A. 2006. Galectin-3 regulates mitochondrial stability and antiapoptotic function in response to anticancer drug in prostate cancer. Cancer Res 66: 3114-3119.
-
(2006)
Cancer Res
, vol.66
, pp. 3114-3119
-
-
Fukumori, T.1
Oka, N.2
Takenaka, Y.3
Nangia-Makker, P.4
Elsamman, E.5
Kasai, T.6
Shono, M.7
Kanayama, H.8
Ellerhorst, J.9
Lotan, R.10
Raz, A.11
-
13
-
-
77949293368
-
Dynamics of galectin-3 in the nucleus and cytoplasm
-
Haudek KC, Spronk KJ, Voss PG, Patterson RJ, Wang JL, Arnoys EJ. 2010. Dynamics of galectin-3 in the nucleus and cytoplasm. Biochim Biophys Acta 1800: 181.
-
(2010)
Biochim Biophys Acta
, vol.1800
, pp. 181
-
-
Haudek, K.C.1
Spronk, K.J.2
Voss, P.G.3
Patterson, R.J.4
Wang, J.L.5
Arnoys, E.J.6
-
14
-
-
67649831425
-
The regulation of inflammation by galectin-3
-
Henderson NC, Sethi T. 2009. The regulation of inflammation by galectin-3. Immunol Rev 230: 160-171.
-
(2009)
Immunol Rev
, vol.230
, pp. 160-171
-
-
Henderson, N.C.1
Sethi, T.2
-
15
-
-
0033870111
-
Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses
-
Hsu DK, Yang RY, Pan Z, Yu L, Salomon DR, Fung-Leung WP, Liu FT. 2000. Targeted disruption of the galectin-3 gene results in attenuated peritoneal inflammatory responses. Am J Pathol 156: 1073-1083.
-
(2000)
Am J Pathol
, vol.156
, pp. 1073-1083
-
-
Hsu, D.K.1
Yang, R.Y.2
Pan, Z.3
Yu, L.4
Salomon, D.R.5
Fung-Leung, W.P.6
Liu, F.T.7
-
16
-
-
60549107575
-
Galectin-3 deficiency reduces the severity of experimental autoimmune encephalomyelitis
-
Jiang H-R, Al Rasebi Z, Mensah-Brown E, Shahin A, Xu D, Goodyear CS, Fukada SY, Liu F-T, Liew FY, Lukic ML. 2009. Galectin-3 deficiency reduces the severity of experimental autoimmune encephalomyelitis. J Immunol 182: 1167-1173.
-
(2009)
J Immunol
, vol.182
, pp. 1167-1173
-
-
Jiang, H.-R.1
Al Rasebi, Z.2
Mensah-Brown, E.3
Shahin, A.4
Xu, D.5
Goodyear, C.S.6
Fukada, S.Y.7
Liu, F.-T.8
Liew, F.Y.9
Lukic, M.L.10
-
17
-
-
33646040686
-
Immune mediated β-cell destruction in vitro and in vivo-A pivotal role for galectin-3
-
Karlsen AE, Størling ZM, Sparre T, Larsen MR, Mahmood A, Størling J, Roepstorff P, Wrzesinski K, Larsen PM, Fey S, Nielsen K, Heding P, Ricordi C, Johannesen J, Kristiansen OP, Christensen UB, Kockum I, Luthman H, Nerup J, Pociot F. 2006. Immune mediated β-cell destruction in vitro and in vivo-A pivotal role for galectin-3, Biochem Biophys Res Commun 344: 406-415.
-
(2006)
Biochem Biophys Res Commun
, vol.344
, pp. 406-415
-
-
Karlsen, A.E.1
Størling, Z.M.2
Sparre, T.3
Larsen, M.R.4
Mahmood, A.5
Størling, J.6
Roepstorff, P.7
Wrzesinski, K.8
Larsen, P.M.9
Fey, S.10
Nielsen, K.11
Heding, P.12
Ricordi, C.13
Johannesen, J.14
Kristiansen, O.P.15
Christensen, U.B.16
Kockum, I.17
Luthman, H.18
Nerup, J.19
Pociot, F.20
more..
-
19
-
-
0031897507
-
Human islets of Langerhans express Fas ligand and undergo apoptosis in response to interleukin-1β and Fas ligation
-
Loweth AC, Wiliams GT, James RFL, Scarpello JHB, Morgan NG. 1998. Human islets of Langerhans express Fas ligand and undergo apoptosis in response to interleukin-1β and Fas ligation. Diabetes 47: 727-732.
-
(1998)
Diabetes
, vol.47
, pp. 727-732
-
-
Loweth, A.C.1
Wiliams, G.T.2
James, R.F.L.3
Scarpello, J.H.B.4
Morgan, N.G.5
-
20
-
-
0035432491
-
Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets
-
Maedler K, Spinas GA, Lehmann R, Sergeev P, Weber M, Fontana A, Kaiser N, Donath MY. 2001. Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets. Diabetes 50: 1683-1690.
-
(2001)
Diabetes
, vol.50
, pp. 1683-1690
-
-
Maedler, K.1
Spinas, G.A.2
Lehmann, R.3
Sergeev, P.4
Weber, M.5
Fontana, A.6
Kaiser, N.7
Donath, M.Y.8
-
21
-
-
0034685681
-
Galectin-3 overexpression protects from cell damage and death by influencing mitochondrial homeostasis
-
Matarrese P, Tinari N, Semeraro ML, Natoli C, Iacobelli S, Malorni W. 2000. Galectin-3 overexpression protects from cell damage and death by influencing mitochondrial homeostasis. FEBS Lett 473: 311-315.
-
(2000)
FEBS Lett
, vol.473
, pp. 311-315
-
-
Matarrese, P.1
Tinari, N.2
Semeraro, M.L.3
Natoli, C.4
Iacobelli, S.5
Malorni, W.6
-
22
-
-
57149129697
-
Targeted disruption of the galectin-3 gene results in decreased susceptibility to multiple low dose streptozotocin-induced diabetes in mice
-
Mensah-Brown EP, Al Rabesi Z, Shahin A, Al Shamsi M, Arsenijevic N, Hsu DK, Liu FT, Lukic ML. 2009. Targeted disruption of the galectin-3 gene results in decreased susceptibility to multiple low dose streptozotocin-induced diabetes in mice. Clin Immunol 130: 83-88.
-
(2009)
Clin Immunol
, vol.130
, pp. 83-88
-
-
Mensah-Brown, E.P.1
Al Rabesi, Z.2
Shahin, A.3
Al Shamsi, M.4
Arsenijevic, N.5
Hsu, D.K.6
Liu, F.T.7
Lukic, M.L.8
-
23
-
-
33751222596
-
On the role of galectins in signal transduction
-
Nakahara S, Raz A. 2006. On the role of galectins in signal transduction. Methods Enzymol 417: 273-289.
-
(2006)
Methods Enzymol
, vol.417
, pp. 273-289
-
-
Nakahara, S.1
Raz, A.2
-
24
-
-
12944299798
-
Gene expression profiles during beta cell maturation and after IL-1β exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1β sensitivity
-
Nielsen K, Kruhøffer M, Ørntoft T, Sparre T, Wang H, Wollheim C, Jørgensen MC, Nerup J, Karlsen AE. 2004. Gene expression profiles during beta cell maturation and after IL-1β exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1β sensitivity. Diabetologia 48: 2185-2199.
-
(2004)
Diabetologia
, vol.48
, pp. 2185-2199
-
-
Nielsen, K.1
Kruhøffer, M.2
Ørntoft, T.3
Sparre, T.4
Wang, H.5
Wollheim, C.6
Jørgensen, M.C.7
Nerup, J.8
Karlsen, A.E.9
-
25
-
-
24744455701
-
Galectin-3 inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by activating Akt in human bladder carcinoma cells
-
Oka N, Nakahara S, Takenaka Y, Fukumori T, Hogan V, Kanayama H, Yanagawa T, Raz A. 2005. Galectin-3 inhibits tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by activating Akt in human bladder carcinoma cells. Cancer Res 65: 7546-7553.
-
(2005)
Cancer Res
, vol.65
, pp. 7546-7553
-
-
Oka, N.1
Nakahara, S.2
Takenaka, Y.3
Fukumori, T.4
Hogan, V.5
Kanayama, H.6
Yanagawa, T.7
Raz, A.8
-
26
-
-
17944369113
-
Accelerated diabetic glomerulopathy in galectin-3/AGE receptor 3 knockout mice
-
Pugliese G, Pricci F, Iacobini C, Leto G, Amadio L, Barsotti P, Frigeri L, Hsu DK, Vlassara H, Liu FT, Di-Mario D. 2001. Accelerated diabetic glomerulopathy in galectin-3/AGE receptor 3 knockout mice. FASEB J 15: 2471-2479.
-
(2001)
FASEB J
, vol.15
, pp. 2471-2479
-
-
Pugliese, G.1
Pricci, F.2
Iacobini, C.3
Leto, G.4
Amadio, L.5
Barsotti, P.6
Frigeri, L.7
Hsu, D.K.8
Vlassara, H.9
Liu, F.T.10
Di-Mario, D.11
-
27
-
-
67349258025
-
Turning 'sweet' on immunity: Galectin-glycan interactions in immune tolerance and inflammation
-
Rabinovich GA, Toscano MA. 2009. Turning 'sweet' on immunity: Galectin-glycan interactions in immune tolerance and inflammation. Nat Rev Immunol 9: 338-352.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 338-352
-
-
Rabinovich, G.A.1
Toscano, M.A.2
-
28
-
-
34447301574
-
An emerging role for galectins in tuning the immune response: Lessons from experimental models of inflammatory disease, autoimmunity and cancer
-
Rabinovich GA, Liu FT, Hirashima M, Anderson A. 2007. An emerging role for galectins in tuning the immune response: Lessons from experimental models of inflammatory disease, autoimmunity and cancer. Scand J Immunol 66: 143-158.
-
(2007)
Scand J Immunol
, vol.66
, pp. 143-158
-
-
Rabinovich, G.A.1
Liu, F.T.2
Hirashima, M.3
Anderson, A.4
-
29
-
-
84859893633
-
The roles of Galectin-3 in autoimmunity and tumor progression
-
Radosavljevic G, Volarevic V, Jovanovic I, Milovanovic M, Pejnovic N, Arsenijevic N, Hsu DK, Lukic ML. 2012. The roles of Galectin-3 in autoimmunity and tumor progression. Immunol Res 52: 100-110.
-
(2012)
Immunol Res
, vol.52
, pp. 100-110
-
-
Radosavljevic, G.1
Volarevic, V.2
Jovanovic, I.3
Milovanovic, M.4
Pejnovic, N.5
Arsenijevic, N.6
Hsu, D.K.7
Lukic, M.L.8
-
30
-
-
8444220527
-
Molecular mechanisms of caspase regulation during apoptosis
-
Riedl SJ, Shi Y. 2004. Molecular mechanisms of caspase regulation during apoptosis. Nat Rev Mol Cell Biol 5: 897-907.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 897-907
-
-
Riedl, S.J.1
Shi, Y.2
-
31
-
-
0036773013
-
Efficacy of 1400W, a novel inhibitor of inducible nitric oxide synthase, in preventing interleukin-1beta-induced suppression of pancreatic islet function in vitro and multiple low-dose streptozotocin-induced diabetes in vivo
-
Rydgren T, Sandler S. 2002. Efficacy of 1400W, a novel inhibitor of inducible nitric oxide synthase, in preventing interleukin-1beta-induced suppression of pancreatic islet function in vitro and multiple low-dose streptozotocin-induced diabetes in vivo . Eur J Endocrinol 147: 543-551.
-
(2002)
Eur J Endocrinol
, vol.147
, pp. 543-551
-
-
Rydgren, T.1
Sandler, S.2
-
32
-
-
33947190764
-
Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection
-
Silva-Monteiro E, Reis Lorenzato L, Kenji Nihei O, Junqueira M, Rabinovich GA, Hsu DK, Liu FT, Savino W, Chammas R, Villa-Verde DM. 2007. Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection. Am J Pathol 170: 546-556.
-
(2007)
Am J Pathol
, vol.170
, pp. 546-556
-
-
Silva-Monteiro, E.1
Reis Lorenzato, L.2
Kenji Nihei, O.3
Junqueira, M.4
Rabinovich, G.A.5
Hsu, D.K.6
Liu, F.T.7
Savino, W.8
Chammas, R.9
Villa-Verde, D.M.10
-
33
-
-
0036435663
-
IL-1β induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis
-
Sparre T, Christensen UB, Larsen PM, Fey SJ, Wrzesinski K, Roepstorff P, Mandrup-Poulsen T, Pociot F, Karlsen AE, Nerup J. 2002. IL-1β induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis. Diabetologia 45: 1550-1561.
-
(2002)
Diabetologia
, vol.45
, pp. 1550-1561
-
-
Sparre, T.1
Christensen, U.B.2
Larsen, P.M.3
Fey, S.J.4
Wrzesinski, K.5
Roepstorff, P.6
Mandrup-Poulsen, T.7
Pociot, F.8
Karlsen, A.E.9
Nerup, J.10
-
34
-
-
2942596542
-
Changes in expression of IL-1 beta influenced proteins in transplanted islets during development of diabetes in diabetes-prone BB rats
-
Sparre T, Christensen UB, Gotfredsen CF, Larsen PM, Fey SJ, Hjernø K, Roepstorff P, Pociot F, Karlsen AE, Nerup J. 2004. Changes in expression of IL-1 beta influenced proteins in transplanted islets during development of diabetes in diabetes-prone BB rats. Diabetologia 47: 892-908.
-
(2004)
Diabetologia
, vol.47
, pp. 892-908
-
-
Sparre, T.1
Christensen, U.B.2
Gotfredsen, C.F.3
Larsen, P.M.4
Fey, S.J.5
Hjernø, K.6
Roepstorff, P.7
Pociot, F.8
Karlsen, A.E.9
Nerup, J.10
-
35
-
-
46949103440
-
Differential roles of galectin-1 and galectin-3 in regulating leukocyte viability and cytokine secretion
-
Stowell SR, Qian Y, Karmakar S, Koyama NS, Dias-Baruffi M, Leffler H, McEver RP, Cummings RD. 2008. Differential roles of galectin-1 and galectin-3 in regulating leukocyte viability and cytokine secretion. J Immunol 180: 3091-3102.
-
(2008)
J Immunol
, vol.180
, pp. 3091-3102
-
-
Stowell, S.R.1
Qian, Y.2
Karmakar, S.3
Koyama, N.S.4
Dias-Baruffi, M.5
Leffler, H.6
McEver, R.P.7
Cummings, R.D.8
-
36
-
-
41949104907
-
Galectin-3 but not galectin-1 induces mast cell death by oxidative stress and mitochondrial permeability transition
-
Suzuki Y, Inoue T, Yoshimaru T, Ra C. 2008. Galectin-3 but not galectin-1 induces mast cell death by oxidative stress and mitochondrial permeability transition. Biochim Biophys Acta 1783: 924-934.
-
(2008)
Biochim Biophys Acta
, vol.1783
, pp. 924-934
-
-
Suzuki, Y.1
Inoue, T.2
Yoshimaru, T.3
Ra, C.4
-
37
-
-
2942591023
-
Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs
-
Takenaka Y, Fukumori T, Yoshii T, Oka N, Inohara H, Kim HR, Bresalier RS, Raz A. 2004. Nuclear export of phosphorylated galectin-3 regulates its antiapoptotic activity in response to chemotherapeutic drugs. Mol Cell Biol 24: 4395-4406.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4395-4406
-
-
Takenaka, Y.1
Fukumori, T.2
Yoshii, T.3
Oka, N.4
Inohara, H.5
Kim, H.R.6
Bresalier, R.S.7
Raz, A.8
-
38
-
-
0037401562
-
Cell death regulation by the Bcl-2 protein family in the mitochondria
-
Tsujimoto Y. 2003. Cell death regulation by the Bcl-2 protein family in the mitochondria. J Cell Physiol 195: 158-167.
-
(2003)
J Cell Physiol
, vol.195
, pp. 158-167
-
-
Tsujimoto, Y.1
-
39
-
-
44049095632
-
Protein-glycan interactions in the control of innate and adaptive immune responses
-
van Kooyk Y, Rabinovich GA. 2008. Protein-glycan interactions in the control of innate and adaptive immune responses. Nat Immunol 9: 593-601.
-
(2008)
Nat Immunol
, vol.9
, pp. 593-601
-
-
van Kooyk, Y.1
Rabinovich, G.A.2
-
40
-
-
84861574827
-
Galectin-3 deficiency prevents concanavalin A-induced hepatitis in mice
-
Volarevic V, Milovanovic M, Ljujic B, Pejnovic N, Arsenijevic N, Nilsson U, Leffler H, Lukic ML. 2012. Galectin-3 deficiency prevents concanavalin A-induced hepatitis in mice. Hepatology 55: 1954-1964.
-
(2012)
Hepatology
, vol.55
, pp. 1954-1964
-
-
Volarevic, V.1
Milovanovic, M.2
Ljujic, B.3
Pejnovic, N.4
Arsenijevic, N.5
Nilsson, U.6
Leffler, H.7
Lukic, M.L.8
-
41
-
-
0030048494
-
Apoptosis mediated by the TNF-related cytokine and receptor families
-
Ware CF, VanArsdale S, VanArsdale TL. 1996. Apoptosis mediated by the TNF-related cytokine and receptor families. J Cell Biochem 60: 47-55.
-
(1996)
J Cell Biochem
, vol.60
, pp. 47-55
-
-
Ware, C.F.1
VanArsdale, S.2
VanArsdale, T.L.3
-
42
-
-
80055021304
-
Hormonal regulation of galectin 3 in trophoblasts and its effects on endometrium
-
Yang H, Taylor HS, Lei C, Cheng C, Zhang W. 2011. Hormonal regulation of galectin 3 in trophoblasts and its effects on endometrium. Reprod Sci 18: 1118-1127.
-
(2011)
Reprod Sci
, vol.18
, pp. 1118-1127
-
-
Yang, H.1
Taylor, H.S.2
Lei, C.3
Cheng, C.4
Zhang, W.5
|