Crystallization and preliminary X-ray diffraction analysis of the complex between a human anti-alpha toxin antibody fragment and alpha toxin

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 69, Issue 3, 2013, Pages 302-305

  Oganesyan, Vaheh ^a   Barnes, Arnita ^a   Tkaczyk, Christine ^b   Ferguson, Andrew ^c   Wu, Herren ^a   Dall'Acqua, William F ^a  

^a MEDIMMUNE   (United States)

^b Mail Stop E3 ^*  (United States)

^c ASTRAZENECA   (United Kingdom)

Author keywords

alpha toxin; MEDI4893; Staphylococcus aureus

Indexed keywords

ALPHA TOXIN; ANTIIDIOTYPIC ANTIBODY; BACTERIAL TOXIN; IMMUNOGLOBULIN F(AB) FRAGMENT; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN;

ARTICLE; CHEMISTRY; CRYSTALLIZATION; GENETICS; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; MEDI4893; METABOLISM; PROTEIN BINDING; STAPHYLOCOCCUS AUREUS; X RAY CRYSTALLOGRAPHY;

ALPHA TOXIN; MEDI4893; STAPHYLOCOCCUS AUREUS;

ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, MONOCLONAL; BACTERIAL TOXINS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; PROTEIN BINDING; RECOMBINANT PROTEINS; STAPHYLOCOCCUS AUREUS;

STAPHYLOCOCCUS AUREUS;

EID: 84875497138     PISSN: None     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S1744309113002881     Document Type: Article

References (21)

1. Bartlett, A. H., Foster, T. J., Hayashida, A. & Park, P. W. (2008). J. Infect. Dis. 198, 1529-1535.
2. Bayer, A. S., Ramos, M. D., Menzies, B. E., Yeaman, M. R., Shen, A. J. & Cheung, A. L. (1997). Infect. Immun. 65, 4652-4660.
3. Bhakdi, S. & Tranum-Jensen, J. (1991). Microbiol. Rev. 55, 733-751.
4. Bubeck-Wardenburg, J., Bae, T., Otto, M., Deleo, F. R. & Schneewind, O. (2007). Nature Med. 13, 1405-1406.
5. Bubeck-Wardenburg, J. & Schneewind, O. (2008). J. Exp. Med. 205, 287-294.
6. Craven, R. R., Gao, X., Allen, I. C., Gris, D., Bubeck-Wardenburg, J., McElvania-Tekippe, E., Ting, J. P. & Duncan, J. A. (2009). PLoS One, 4, e7446.
7. Inoshima, I., Inoshima, N.,Wilke, G. A., Powers, M. E., Frank, K. M.,Wang, Y. & Bubeck-Wardenburg, J.(2011). Nature Med.17.1310-1314.
8. Inoshima, N., Wang, Y. & Bubeck-Wardenburg, J. (2012). J. Invest. Dermatol. 132, 1513-1516.
9. Kabsch, W. (2010). Acta Cryst. D66, 125-132.
10. Kennedy, A. D., Bubeck Wardenburg, J., Gardner, D. J., Long, D., Whitney, A. R., Braughton, K. R., Schneewind, O. & DeLeo, F. R. (2010). J. Infect. Dis. 202, 1050-1058.
11. Klevens, R. M. et al. (2007). J. Am. Med. Assoc. 298, 1763-1771.
12. Lowy, F. D. (1998). N. Engl. J. Med. 339, 520-532.
13. McCoy, A. J., Grosse-Kunstleve, R. W., Storoni, L. C. & Read, R. J. (2005). Acta Cryst. D61, 458-464.
14. Matthews, B. W. (1968). J. Mol. Biol. 33, 491-497.
15. Powers,M. E., Kim, H. K.,Wang, Y. & Bubeck-Wardenburg, J. (2012). J. Infect. Dis. 206, 352-356.
16. Song, L., Hobaugh, M. R., Shustak, C., Cheley, S., Bayley, H. & Gouaux, J. E. (1996). Science, 274, 1859-1866.
17. Tkaczyk, C., Hua, L., Varkey, R., Shi, Y., Dettinger, L., Woods, R., Barnes, A., MacGill, R. S., Wilson, S., Chowdhury, P., Stover, C. K. & Sellman, B. R. (2012). Clin. Vaccine Immunol. 19, 377-385.
18. Vonrhein, C., Flensburg, C., Keller, P., Sharff, A., Smart, O., Paciorek, W., Womack, T. & Bricogne, G. (2011). Acta Cryst. D67, 293-302.
19. Walker, B., Krishnasastry, M., Zorn, L., Kasianowicz, J. & Bayley, H. (1992). J. Biol. Chem. 267, 10902-10909.
20. Wilke, G. A. & Bubeck-Wardenburg, J. (2010). Proc. Natl Acad. Sci. USA, 107, 13473-13478.
21. Winn, M. D. et al. (2011). Acta Cryst. D67, 235-242.