-
1
-
-
0032786697
-
Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies. EURODEM Incidence Research Group
-
Andersen K, Launer LJ, Dewey ME, Letenneur L, Ott A, Copeland JR, Dartigues JF, Kragh-Sorensen P, Baldereschi M, Brayne C, Lobo A, Martinez-Lage JM, Stijnen T, Hofman A. 1999. Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies. EURODEM Incidence Research Group. Neurology 53: 1992-1997.
-
(1999)
Neurology
, vol.53
, pp. 1992-1997
-
-
Andersen, K.1
Launer, L.J.2
Dewey, M.E.3
Letenneur, L.4
Ott, A.5
Copeland, J.R.6
Dartigues, J.F.7
Kragh-Sorensen, P.8
Baldereschi, M.9
Brayne, C.10
Lobo, A.11
Martinez-Lage, J.M.12
Stijnen, T.13
Hofman, A.14
-
2
-
-
44449120224
-
Simvastatin impairs spatial memory in rats at a specific dose level
-
Baytan SH, Alkanat M, Okuyan M, Ekinci M, Gedikli E, Ozeren M, Akgun A. 2008. Simvastatin impairs spatial memory in rats at a specific dose level. Tohoku J Exp Med 214: 341-349.
-
(2008)
Tohoku J Exp Med
, vol.214
, pp. 341-349
-
-
Baytan, S.H.1
Alkanat, M.2
Okuyan, M.3
Ekinci, M.4
Gedikli, E.5
Ozeren, M.6
Akgun, A.7
-
3
-
-
2442557294
-
Brain cholesterol: Long secret life behind a barrier
-
Bjorkhem I, Meaney S. 2004. Brain cholesterol: Long secret life behind a barrier. Arterioscler Thromb Vasc Biol 24: 806-815.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 806-815
-
-
Bjorkhem, I.1
Meaney, S.2
-
4
-
-
75849142894
-
Altered cholesterol and fatty acid metabolism in Huntington disease
-
Block RC, Dorsey ER, Beck CA, Brenna JT, Shoulson I. 2010. Altered cholesterol and fatty acid metabolism in Huntington disease. J Clin Lipidol 4: 17-23.
-
(2010)
J Clin Lipidol
, vol.4
, pp. 17-23
-
-
Block, R.C.1
Dorsey, E.R.2
Beck, C.A.3
Brenna, J.T.4
Shoulson, I.5
-
5
-
-
0029671454
-
Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein
-
Bodovitz S, Klein WL. 1996. Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein. J Biol Chem 271: 4436-4440.
-
(1996)
J Biol Chem
, vol.271
, pp. 4436-4440
-
-
Bodovitz, S.1
Klein, W.L.2
-
6
-
-
0030941803
-
The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
-
Brown MS, Goldstein JL. 1997. The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell 89: 331-340.
-
(1997)
Cell
, vol.89
, pp. 331-340
-
-
Brown, M.S.1
Goldstein, J.L.2
-
7
-
-
0033613147
-
A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood
-
Brown MS, Goldstein JL. 1999. A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood. Proc Natl Acad Sci USA 96: 11041-11048.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 11041-11048
-
-
Brown, M.S.1
Goldstein, J.L.2
-
8
-
-
0016075974
-
Plasma concentration of LH, FSH, prolactin, progesterone, and estradiol-17 beta throughout the 4-day estrous cycle of the rat
-
Butcher RL, Collins WE, Fugo NW. 1974. Plasma concentration of LH, FSH, prolactin, progesterone, and estradiol-17 beta throughout the 4-day estrous cycle of the rat. Endocrinology 94: 1704-1708.
-
(1974)
Endocrinology
, vol.94
, pp. 1704-1708
-
-
Butcher, R.L.1
Collins, W.E.2
Fugo, N.W.3
-
9
-
-
0035102386
-
Augmented senile plaque load in aged female beta amyloid precursor protein-transgenic mice
-
Callahan M, Lipinski W, Bian F, Durham R, Pack A, Walker L. 2001. Augmented senile plaque load in aged female beta amyloid precursor protein-transgenic mice. Am J Pathol 158: 1173-1177.
-
(2001)
Am J Pathol
, vol.158
, pp. 1173-1177
-
-
Callahan, M.1
Lipinski, W.2
Bian, F.3
Durham, R.4
Pack, A.5
Walker, L.6
-
10
-
-
33748431934
-
Lack of LDL receptor aggravetes learning deficits and amyloid deposits in Alzheimer transgenic mice
-
Cao D, Fukuchi K, Wan H, Kim H, Li L. 2006. Lack of LDL receptor aggravetes learning deficits and amyloid deposits in Alzheimer transgenic mice. Neurobiol Ageing 27: 1632-1643.
-
(2006)
Neurobiol Ageing
, vol.27
, pp. 1632-1643
-
-
Cao, D.1
Fukuchi, K.2
Wan, H.3
Kim, H.4
Li, L.5
-
11
-
-
0021067911
-
Biosynthesis of N- and O-linked oligosaccharides of the low-density lipoprotein receptor
-
Cummings RD, Kornfeld S, Schneider WJ, Hobgood KK, Tolleshaug H, Brown MS, Goldstein JL. 1983. Biosynthesis of N- and O-linked oligosaccharides of the low-density lipoprotein receptor. J Biol Chem 258: 15261-15273.
-
(1983)
J Biol Chem
, vol.258
, pp. 15261-15273
-
-
Cummings, R.D.1
Kornfeld, S.2
Schneider, W.J.3
Hobgood, K.K.4
Tolleshaug, H.5
Brown, M.S.6
Goldstein, J.L.7
-
13
-
-
3543104951
-
Thematic review series: Brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal
-
Dietschy JM, Turley SD. 2004. Thematic review series: Brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal. J Lipid Res 45: 1375-1397.
-
(2004)
J Lipid Res
, vol.45
, pp. 1375-1397
-
-
Dietschy, J.M.1
Turley, S.D.2
-
14
-
-
39849102805
-
Regulation of sterol synthesis in eukaryotes
-
Espenshade PJ, Hughes AL. 2007. Regulation of sterol synthesis in eukaryotes. Annu Rev Genet 41: 401-427.
-
(2007)
Annu Rev Genet
, vol.41
, pp. 401-427
-
-
Espenshade, P.J.1
Hughes, A.L.2
-
15
-
-
0024340647
-
Effect of inhibiting N-glycosylation on the stability and binding activity of the low-density lipoprotein receptor
-
Filipovic I. 1989. Effect of inhibiting N-glycosylation on the stability and binding activity of the low-density lipoprotein receptor. J Biol Chem 264: 8815-8820.
-
(1989)
J Biol Chem
, vol.264
, pp. 8815-8820
-
-
Filipovic, I.1
-
16
-
-
0033519601
-
The role of cholesterol in the biosynthesis of beta-amyloid
-
Frears ER, Stephens DJ, Walters CE, Davies H, Austen BM. 1999. The role of cholesterol in the biosynthesis of beta-amyloid. Neuroreport 10: 1699-1705.
-
(1999)
Neuroreport
, vol.10
, pp. 1699-1705
-
-
Frears, E.R.1
Stephens, D.J.2
Walters, C.E.3
Davies, H.4
Austen, B.M.5
-
17
-
-
0025120211
-
Regulation of the mevalonate pathway
-
Goldstein JL, Brown MS. 1990. Regulation of the mevalonate pathway. Nature 343: 425-430.
-
(1990)
Nature
, vol.343
, pp. 425-430
-
-
Goldstein, J.L.1
Brown, M.S.2
-
18
-
-
1842844488
-
Severe irritability associated with statin cholesterol-lowering drugs
-
Golomb BA, Kane T, Dimsdale JE. 2004. Severe irritability associated with statin cholesterol-lowering drugs. QJM 97: 229-235.
-
(2004)
QJM
, vol.97
, pp. 229-235
-
-
Golomb, B.A.1
Kane, T.2
Dimsdale, J.E.3
-
19
-
-
0021961770
-
3-Hydroxy-3-methylglutaryl-coenzyme A reductase is present in peroxisomes in normal rat liver cells
-
Keller GA, Barton MC, Shapiro DJ, Singer SJ. 1985. 3-Hydroxy-3-methylglutaryl-coenzyme A reductase is present in peroxisomes in normal rat liver cells. Proc Natl Acad Sci USA 82: 770-774.
-
(1985)
Proc Natl Acad Sci USA
, vol.82
, pp. 770-774
-
-
Keller, G.A.1
Barton, M.C.2
Shapiro, D.J.3
Singer, S.J.4
-
20
-
-
84862005865
-
Sex differences, gonadal hormones and the fear extinction network: Implications for anxiety disorders
-
Lebron-Milad K, Milad MR. 2012. Sex differences, gonadal hormones and the fear extinction network: Implications for anxiety disorders. Biol Mood Anxiety Disord 2: 3.
-
(2012)
Biol Mood Anxiety Disord
, vol.2
, pp. 3
-
-
Lebron-Milad, K.1
Milad, M.R.2
-
22
-
-
84864251377
-
Oligomeric amyloid-beta peptide affects the expression of genes involved in steroid and lipid metabolism in primary neurons
-
Malik B, Fernandes C, KilliK R, Wroe R, Usardi A, Williamson R, Kellie S, Anderton BH, Reynolds CH. 2012. Oligomeric amyloid-beta peptide affects the expression of genes involved in steroid and lipid metabolism in primary neurons. Neurochem Int 61: 321-333.
-
(2012)
Neurochem Int
, vol.61
, pp. 321-333
-
-
Malik, B.1
Fernandes, C.2
KilliK, R.3
Wroe, R.4
Usardi, A.5
Williamson, R.6
Kellie, S.7
Anderton, B.H.8
Reynolds, C.H.9
-
23
-
-
79954579587
-
Nutrition and human health from a sex-gender perspective
-
Marino M, Masella R, Bulzomi P, Campesi I, Malorni W, Franconi F. 2011. Nutrition and human health from a sex-gender perspective. Mol Aspects Med 32: 1-70.
-
(2011)
Mol Aspects Med
, vol.32
, pp. 1-70
-
-
Marino, M.1
Masella, R.2
Bulzomi, P.3
Campesi, I.4
Malorni, W.5
Franconi, F.6
-
25
-
-
0346238597
-
Age-related changes of isoprenoid biosynthesis in rat liver and brain
-
Pallottini V, Marino M, Cavallini G, Bergamini E, Trentalance A. 2003. Age-related changes of isoprenoid biosynthesis in rat liver and brain. Biogerontology 4: 371-378.
-
(2003)
Biogerontology
, vol.4
, pp. 371-378
-
-
Pallottini, V.1
Marino, M.2
Cavallini, G.3
Bergamini, E.4
Trentalance, A.5
-
26
-
-
30344481928
-
Rat HMGCoA reductase activation in thioacetamide-induced liver injury is related to an increased reactive oxygen species content
-
Pallottini V, Martini C, Bassi AM, Romano P, Nanni G, Trentalance A. 2006. Rat HMGCoA reductase activation in thioacetamide-induced liver injury is related to an increased reactive oxygen species content. J Hepatol 44: 368-374.
-
(2006)
J Hepatol
, vol.44
, pp. 368-374
-
-
Pallottini, V.1
Martini, C.2
Bassi, A.M.3
Romano, P.4
Nanni, G.5
Trentalance, A.6
-
27
-
-
37349057499
-
Age-related HMG-CoA reductase deregulation depends on ROS-induced p38 activation
-
Pallottini V, Martini C, Cavallini G, Bergamini E, Mustard KJ, Hardie DG, Trentalance A. 2007. Age-related HMG-CoA reductase deregulation depends on ROS-induced p38 activation. Mech Ageing Dev 128: 688-695.
-
(2007)
Mech Ageing Dev
, vol.128
, pp. 688-695
-
-
Pallottini, V.1
Martini, C.2
Cavallini, G.3
Bergamini, E.4
Mustard, K.J.5
Hardie, D.G.6
Trentalance, A.7
-
28
-
-
5644226496
-
Mechanisms underlying the impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in aged rat liver
-
Pallottini V, Montanari L, Cavallini G, Bergamini E, Gori Z, Trentalance A. 2004. Mechanisms underlying the impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in aged rat liver. Mech Ageing Dev 125: 633-639.
-
(2004)
Mech Ageing Dev
, vol.125
, pp. 633-639
-
-
Pallottini, V.1
Montanari, L.2
Cavallini, G.3
Bergamini, E.4
Gori, Z.5
Trentalance, A.6
-
29
-
-
33748376485
-
Estrogen and different aspects of vascular disease in women and men
-
Pepine CJ, Nichols WW, Pauly DF. 2006. Estrogen and different aspects of vascular disease in women and men. Circ Res 99: 459-461.
-
(2006)
Circ Res
, vol.99
, pp. 459-461
-
-
Pepine, C.J.1
Nichols, W.W.2
Pauly, D.F.3
-
30
-
-
0036802874
-
Role of glia in synapse development
-
Pfrieger FW. 2002. Role of glia in synapse development. Curr Opin Neurobiol 12: 486-490.
-
(2002)
Curr Opin Neurobiol
, vol.12
, pp. 486-490
-
-
Pfrieger, F.W.1
-
31
-
-
0037429703
-
Role of cholesterol in synapse formation and function
-
Pfrieger FW. 2003. Role of cholesterol in synapse formation and function. Biochim Biophys Acta 1610: 271-280.
-
(2003)
Biochim Biophys Acta
, vol.1610
, pp. 271-280
-
-
Pfrieger, F.W.1
-
32
-
-
0024366266
-
Isolation and characterization of an extragenic suppressor of the low-density lipoprotein receptor-deficient phenotype of a Chinese hamster ovary cell mutant
-
Reddy P, Krieger M. 1989. Isolation and characterization of an extragenic suppressor of the low-density lipoprotein receptor-deficient phenotype of a Chinese hamster ovary cell mutant. Mol Cell Biol 9: 4799-4806.
-
(1989)
Mol Cell Biol
, vol.9
, pp. 4799-4806
-
-
Reddy, P.1
Krieger, M.2
-
33
-
-
0033833354
-
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
-
Refolo LM, Malester B, LaFrancois J, Bryant-Thomas T, Wang R, Tint GS, Sambamurti K, Duff K, Pappolla MA. 2000. Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model. Neurobiol Dis 7: 321-331.
-
(2000)
Neurobiol Dis
, vol.7
, pp. 321-331
-
-
Refolo, L.M.1
Malester, B.2
LaFrancois, J.3
Bryant-Thomas, T.4
Wang, R.5
Tint, G.S.6
Sambamurti, K.7
Duff, K.8
Pappolla, M.A.9
-
34
-
-
0034518420
-
The role of orphan nuclear receptors in the regulation of cholesterol homeostasis
-
Repa JJ, Mangelsdorf DJ. 2000. The role of orphan nuclear receptors in the regulation of cholesterol homeostasis. Annu Rev Cell Dev Biol 16: 459-481.
-
(2000)
Annu Rev Cell Dev Biol
, vol.16
, pp. 459-481
-
-
Repa, J.J.1
Mangelsdorf, D.J.2
-
35
-
-
84864517488
-
Regulation of cholesterol biosynthetic pathway in different regions of the rat central nervous system
-
Segatto M, Trapani L, Lecis C, Pallottini V. 2012. Regulation of cholesterol biosynthetic pathway in different regions of the rat central nervous system. Acta Physiol (Oxf) 206: 62-71.
-
(2012)
Acta Physiol (Oxf)
, vol.206
, pp. 62-71
-
-
Segatto, M.1
Trapani, L.2
Lecis, C.3
Pallottini, V.4
-
36
-
-
79960693880
-
Age- and sex-related differences in extra-hepatic low-density lipoprotein receptor
-
Segatto M, Trapani L, Marino M, Pallottini V. 2011. Age- and sex-related differences in extra-hepatic low-density lipoprotein receptor. J Cell Physiol 226: 2610-2616.
-
(2011)
J Cell Physiol
, vol.226
, pp. 2610-2616
-
-
Segatto, M.1
Trapani, L.2
Marino, M.3
Pallottini, V.4
-
37
-
-
0037171095
-
Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice
-
Shie FS, Jin LW, Cook DG, Leverenz JB, LeBoeuf RC. 2002. Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice. Neuroreport 13: 455-459.
-
(2002)
Neuroreport
, vol.13
, pp. 455-459
-
-
Shie, F.S.1
Jin, L.W.2
Cook, D.G.3
Leverenz, J.B.4
LeBoeuf, R.C.5
-
38
-
-
0029072340
-
Sexual differentiation of the human hypothalamus in relation to gender and sexual orientation
-
Swaab DF, Hofman MA. 1995. Sexual differentiation of the human hypothalamus in relation to gender and sexual orientation. Trends Neurosci 18: 264-270.
-
(1995)
Trends Neurosci
, vol.18
, pp. 264-270
-
-
Swaab, D.F.1
Hofman, M.A.2
-
39
-
-
0020522133
-
The LDL receptor locus in familial hypercholesterolemia: Multiple mutations disrupt transport and processing of a membrane receptor
-
Tolleshaug H, Hobgood KK, Brown MS, Goldstein JL. 1983. The LDL receptor locus in familial hypercholesterolemia: Multiple mutations disrupt transport and processing of a membrane receptor. Cell 32: 941-951.
-
(1983)
Cell
, vol.32
, pp. 941-951
-
-
Tolleshaug, H.1
Hobgood, K.K.2
Brown, M.S.3
Goldstein, J.L.4
-
40
-
-
78349255044
-
Age-related hypercholesterolemia and HMG-CoA reductase dysregulation: Sex does matter (A gender perspective)
-
Trapani L, Pallottini V. 2010. Age-related hypercholesterolemia and HMG-CoA reductase dysregulation: Sex does matter (A gender perspective). Curr Gerontol Geriatr Res 2010: 1-7.
-
(2010)
Curr Gerontol Geriatr Res
, vol.2010
, pp. 1-7
-
-
Trapani, L.1
Pallottini, V.2
-
41
-
-
79958041055
-
Short- and long-term regulation of 3-hydroxy 3-methylglutaryl coenzyme A reductase by a 4-methylcoumarin
-
Trapani L, Segatto M, Simeoni V, Balducci V, Dhawan A, Parmar VS, Prasad AK, Saso L, Incerpi S, Pallottini V. 2011. Short- and long-term regulation of 3-hydroxy 3-methylglutaryl coenzyme A reductase by a 4-methylcoumarin. Biochimie 93: 1165-1171.
-
(2011)
Biochimie
, vol.93
, pp. 1165-1171
-
-
Trapani, L.1
Segatto, M.2
Simeoni, V.3
Balducci, V.4
Dhawan, A.5
Parmar, V.S.6
Prasad, A.K.7
Saso, L.8
Incerpi, S.9
Pallottini, V.10
-
42
-
-
74649086809
-
Hypercholesterolemia and 3-hydroxy-3-methylglutaryl coenzyme A reductase regulation in aged female rats
-
Trapani L, Violo F, Pallottini V. 2010. Hypercholesterolemia and 3-hydroxy-3-methylglutaryl coenzyme A reductase regulation in aged female rats. Exp Gerontol 45: 119-128.
-
(2010)
Exp Gerontol
, vol.45
, pp. 119-128
-
-
Trapani, L.1
Violo, F.2
Pallottini, V.3
-
43
-
-
39249084075
-
Cholesterol retention in Alzheimer's brain is responsible for high beta- and gamma-secretase activities and Abeta production
-
Xiong H, Callaghan D, Jones A, Walker DG, Lue LF, Beach TG, Sue LI, Woulfe J, Xu H, Stanimirovic DB, Zhang W. 2008. Cholesterol retention in Alzheimer's brain is responsible for high beta- and gamma-secretase activities and Abeta production. Neurobiol Dis 29: 422-437.
-
(2008)
Neurobiol Dis
, vol.29
, pp. 422-437
-
-
Xiong, H.1
Callaghan, D.2
Jones, A.3
Walker, D.G.4
Lue, L.F.5
Beach, T.G.6
Sue, L.I.7
Woulfe, J.8
Xu, H.9
Stanimirovic, D.B.10
Zhang, W.11
-
44
-
-
34347343830
-
Impact of HMG-CoA reductase inhibition on brain pathology
-
Zipp F, Waiczies S, Aktas O, Neuhaus O, Hemmer B, Schraven B, Nitsch R, Hartung HP. 2007. Impact of HMG-CoA reductase inhibition on brain pathology. Trends Pharmacol Sci 28: 342-349.
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 342-349
-
-
Zipp, F.1
Waiczies, S.2
Aktas, O.3
Neuhaus, O.4
Hemmer, B.5
Schraven, B.6
Nitsch, R.7
Hartung, H.P.8
-
45
-
-
78149255128
-
Low density lipoprotein receptor-related protein-1: A serial clearance homeostatic mechanism controlling Alzheimer's amyloid beta peptide elimination from the brain
-
Zlokovic BV, Deane R, Sagare AP, Bell RD, Winkler EA. 2010. Low density lipoprotein receptor-related protein-1: A serial clearance homeostatic mechanism controlling Alzheimer's amyloid beta peptide elimination from the brain. J Neurochem 115: 1077-1089.
-
(2010)
J Neurochem
, vol.115
, pp. 1077-1089
-
-
Zlokovic, B.V.1
Deane, R.2
Sagare, A.P.3
Bell, R.D.4
Winkler, E.A.5
|