Structure of the human angiotensin II type 1 (AT1) receptor bound to angiotensin II from multiple chemoselective photoprobe contacts reveals a unique peptide binding mode

Journal of Biological Chemistry

Volumn 288, Issue 12, 2013, Pages 8187-8197

  Fillion, Dany ^a   Cabana, Jérôme ^a   Guillemette, Gaétan ^a   Leduc, Richard ^a   Lavigne, Pierre ^a   Escher, Emanuel ^a  

^a UNIVERSITY OF SHERBROOKE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; BINDING ENERGY; COVALENT BONDS; LIGANDS; PEPTIDES; SULFUR COMPOUNDS;

EXTRACELLULAR LOOP 2; G PROTEIN COUPLED RECEPTORS; LIGAND-BINDING SITES; LOW MOLECULAR WEIGHT; PHOTOAFFINITY LABELING; PHYSIOLOGICAL CONDITION; STRUCTURE DETERMINATION; TRANS-MEMBRANE DOMAINS;

CRYSTAL STRUCTURE;

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; CHEMOKINE RECEPTOR CXCR4; DISULFIDE; G PROTEIN COUPLED RECEPTOR; METHIONINE;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DISULFIDE BOND; LIGAND BINDING; MOLECULAR PROBE; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN INTERACTION; PROTEIN STRUCTURE; RECEPTOR BINDING; RECEPTOR UPREGULATION; STRUCTURAL HOMOLOGY;

EID: 84875474851     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.442053     Document Type: Article

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