-
1
-
-
0036729484
-
Seven-transmembrane receptors
-
Pierce, K. L.; Premont, R. T.; Lefkowitz, R. J. Seven-transmembrane receptors. Nat. Rev. Mol Cell Biol. 2002, 3, 639-650.
-
(2002)
Nat. Rev. Mol Cell Biol.
, vol.3
, pp. 639-650
-
-
Pierce, K.L.1
Premont, R.T.2
Lefkowitz, R.J.3
-
2
-
-
0033118334
-
Molecular tinkering of G protein-coupled receptors: An evolutionary success
-
Bockaert, J.; Pin, J. P. Molecular tinkering of G protein-coupled receptors: an evolutionary success. Embo J. 1999, 18,1723-1729.
-
(1999)
Embo J.
, vol.18
, pp. 1723-1729
-
-
Bockaert, J.1
Pin, J.P.2
-
3
-
-
0038024615
-
The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints
-
Fredriksson, R.; Lagerstrom, M. C.; Lundin, L. G.; Schioth, H. B. The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints. Mol Pharmacol. 2003, 63, 1256-1272.
-
(2003)
Mol Pharmacol.
, vol.63
, pp. 1256-1272
-
-
Fredriksson, R.1
Lagerstrom, M.C.2
Lundin, L.G.3
Schioth, H.B.4
-
4
-
-
33947356279
-
G protein coupled receptor structure and activation
-
Kobilka, B. K. G protein coupled receptor structure and activation. Biochim. Biophys. Acta 2007, 1768, 794-807.
-
(2007)
Biochim. Biophys. Acta
, vol.1768
, pp. 794-807
-
-
Kobilka, B.K.1
-
5
-
-
0034464742
-
Uncovering molecular mechanisms involved in activation of G protein-coupled receptors
-
Gether, U. Uncovering molecular mechanisms involved in activation of G protein-coupled receptors. Endocr. Rev. 2000, 21, 90-113.
-
(2000)
Endocr. Rev.
, vol.21
, pp. 90-113
-
-
Gether, U.1
-
6
-
-
0032504237
-
G protein-coupled receptors. I. Diversity of receptor-ligand interactions
-
Ji, T. H.; Grossmann, M.; Ji, I. G protein-coupled receptors. I. Diversity of receptor-ligand interactions. J. Biol. Chem. 1998, 273, 17299-17302.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17299-17302
-
-
Ji, T.H.1
Grossmann, M.2
Ji, I.3
-
7
-
-
33846889729
-
Photoaffinity labeling and its application in structural biology
-
Vodovozova, E. L. Photoaffinity labeling and its application in structural biology. Biochemistry (Mose.) 2007, 72, 1-20.
-
(2007)
Biochemistry (Mose.)
, vol.72
, pp. 1-20
-
-
Vodovozova, E.L.1
-
8
-
-
0036514084
-
Photoaffinity labeling in drug discovery and developments: Chemical gateway for entering proteomic frontier
-
Hatanaka, Y.; Sadakane, Y. Photoaffinity labeling in drug discovery and developments: chemical gateway for entering proteomic frontier. Curr. Top. Med. Chem. 2002, 2, 271-288.
-
(2002)
Curr. Top. Med. Chem.
, vol.2
, pp. 271-288
-
-
Hatanaka, Y.1
Sadakane, Y.2
-
9
-
-
0033951038
-
Using photolabile ligands in drug discovery and development
-
Dorman, G.; Prestwich, G. D. Using photolabile ligands in drug discovery and development. Trends Biotechnol 2000, 18, 64-77.
-
(2000)
Trends Biotechnol
, vol.18
, pp. 64-77
-
-
Dorman, G.1
Prestwich, G.D.2
-
10
-
-
0000065869
-
Photoaffinity labeling in biological signal transduction
-
Dorman, G. Photoaffinity labeling in biological signal transduction. Top. Curr. Chem. 2000, 211, 169-225.
-
(2000)
Top. Curr. Chem.
, vol.211
, pp. 169-225
-
-
Dorman, G.1
-
11
-
-
0033824138
-
International union of pharmacology. XXIII. The angiotensin II receptors
-
de Gasparo, M.; Catt, K. J.; Inagami, T.; Wright, J. W.; Unger, T. International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol. Rev. 2000, 52, 415-472.
-
(2000)
Pharmacol. Rev.
, vol.52
, pp. 415-472
-
-
De Gasparo, M.1
Catt, K.J.2
Inagami, T.3
Wright, J.W.4
Unger, T.5
-
12
-
-
0033324715
-
Determination of peptide contact points in the human angiotensin II type i receptor (AT1) with photosensitive analogs of angiotensin II
-
Laporte, S. A.; Boucard, A. A.; Servant, G.; Guillemette, G.; Leduc, R.; Escher, E. Determination of peptide contact points in the human angiotensin II type I receptor (AT1) with photosensitive analogs of angiotensin II Mol Endocrinol. 1999, 13, 578-586.
-
(1999)
Mol Endocrinol.
, vol.13
, pp. 578-586
-
-
Laporte, S.A.1
Boucard, A.A.2
Servant, G.3
Guillemette, G.4
Leduc, R.5
Escher, E.6
-
13
-
-
0034663965
-
Photolabeling identifies position 172 of the human AT(1) receptor as a ligand contact point: Receptorbound angiotensin II adopts an extended structure
-
Boucard, A. A.; Wilkes, B. C.; Laporte, S. A.; Escher, E.; Guillemette, G.; Leduc, R. Photolabeling identifies position 172 of the human AT(1) receptor as a ligand contact point: receptorbound angiotensin II adopts an extended structure. Biochemistry 2000, 39, 9662-9670.
-
(2000)
Biochemistry
, vol.39
, pp. 9662-9670
-
-
Boucard, A.A.1
Wilkes, B.C.2
Laporte, S.A.3
Escher, E.4
Guillemette, G.5
Leduc, R.6
-
14
-
-
22844442348
-
Determining the environment of the ligand binding pocket of the human angiotensin II type i (hAT1) receptor using the methionine proximity assay
-
Clement, M.; Martin, S. S.; Beaulieu, M. E.; Chamberland, C.; Lavigne, P.; Leduc, R.; Guillemette, G.; Escher, E. Determining the environment of the ligand binding pocket of the human angiotensin II type I (hAT1) receptor using the methionine proximity assay. J. Biol. Chem. 2005, 280, 27121-27129.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 27121-27129
-
-
Clement, M.1
Martin, S.S.2
Beaulieu, M.E.3
Chamberland, C.4
Lavigne, P.5
Leduc, R.6
Guillemette, G.7
Escher, E.8
-
15
-
-
0037016016
-
Residues 293 and 294 are ligand contact points of the human angiotensin type 1 receptor
-
Perodin, J.; Deraet, M.; Auger-Messier, M.; Boucard, A. A.; Rihakova, L.; Beaulieu, M. E.; Lavigne, P.; Parent, J. L.; Guillemette, G.; Leduc, R.; Escher, E. Residues 293 and 294 are ligand contact points of the human angiotensin type 1 receptor. Biochemistry 2002, 41, 14348-14356.
-
(2002)
Biochemistry
, vol.41
, pp. 14348-14356
-
-
Perodin, J.1
Deraet, M.2
Auger-Messier, M.3
Boucard, A.A.4
Rihakova, L.5
Beaulieu, M.E.6
Lavigne, P.7
Parent, J.L.8
Guillemette, G.9
Leduc, R.10
Escher, E.11
-
16
-
-
70350399628
-
Activation induces structural changes in the liganded angiotensin II type 1 receptor
-
Clement, M.; Cabana, J.; Holleran, B. J.; Leduc, R.; Guillemette, G.; Lavigne, P.; Escher, E. Activation induces structural changes in the liganded angiotensin II type 1 receptor. J. Biol. Chem. 2009, 284, 26603-26612.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 26603-26612
-
-
Clement, M.1
Cabana, J.2
Holleran, B.J.3
Leduc, R.4
Guillemette, G.5
Lavigne, P.6
Escher, E.7
-
17
-
-
3042850174
-
On the structural basis of the hypertensive properties of angiotensin II: A solved mystery or a controversial issue?
-
Tzakos, A. G.; Gerothanassis, I. P.; Troganis, A. N. On the structural basis of the hypertensive properties of angiotensin II: a solved mystery or a controversial issue? Curr. Top. Med. Chem. 2004, 4, 431-444.
-
(2004)
Curr. Top. Med. Chem.
, vol.4
, pp. 431-444
-
-
Tzakos, A.G.1
Gerothanassis, I.P.2
Troganis, A.N.3
-
18
-
-
0018448926
-
Structural features of angiotensin II which are important for biologic activity
-
Peach, M. J. Structural features of angiotensin II which are important for biologic activity. Kidney Int. Suppl 1979, S3-6.
-
(1979)
Kidney Int. Suppl
-
-
Peach, M.J.1
-
19
-
-
0016182679
-
Pharmacology of angiotensin
-
Regoli, D.; Park, W. K.; Rioux, F. Pharmacology of angiotensin. Pharmacol. Rev. 1974, 26, 69-123.
-
(1974)
Pharmacol. Rev.
, vol.26
, pp. 69-123
-
-
Regoli, D.1
Park, W.K.2
Rioux, F.3
-
20
-
-
0001591377
-
Structure activity relationship in angiotensin II analogs
-
Springer: New York-Heidelberg-Berlin
-
Khosla, M.; Smeby, R.; Bumpus, F. Structure activity relationship in angiotensin II analogs, In Handbook of Experimental Pharmacology; Springer: New York-Heidelberg-Berlin, 1974; Vol XXXVII, pp 126-156.
-
(1974)
Handbook of Experimental Pharmacology
, vol.37
, pp. 126-156
-
-
Khosla, M.1
Smeby, R.2
Bumpus, F.3
-
21
-
-
0032506041
-
Mechanism of constitutive activation of the ATI receptor: Influence of the size of the agonist switch binding residue Asn(111)
-
Feng, Y. H.; Miura, S.; Husain, A.; Karnik, S. S. Mechanism of constitutive activation of the ATI receptor: influence of the size of the agonist switch binding residue Asn(111). Biochemistry 1998, 37, 15791-15798.
-
(1998)
Biochemistry
, vol.37
, pp. 15791-15798
-
-
Feng, Y.H.1
Miura, S.2
Husain, A.3
Karnik, S.S.4
-
22
-
-
0030300155
-
The active state of the ATI angiotensin receptor is generated by angiotensin II induction
-
Noda, K.; Feng, Y. H.; Liu, X. P.; Saad, Y.; Husain, A.; Karnik, S. S. The active state of the ATI angiotensin receptor is generated by angiotensin II induction. Biochemistry 1996, 35, 16435-16442.
-
(1996)
Biochemistry
, vol.35
, pp. 16435-16442
-
-
Noda, K.1
Feng, Y.H.2
Liu, X.P.3
Saad, Y.4
Husain, A.5
Karnik, S.S.6
-
23
-
-
33645658328
-
Stereospecific synthesis of a carbene-generating angiotensin II analogue for comparative photoaffinity labeling: Improved incorporation and absence of methionine selectivity
-
Fillion, D.; Deraet, M.; Holleran, B. J.; Escher, E. Stereospecific synthesis of a carbene-generating angiotensin II analogue for comparative photoaffinity labeling: improved incorporation and absence of methionine selectivity. J. Med. Chem. 2006, 49, 2200-2209.
-
(2006)
J. Med. Chem.
, vol.49
, pp. 2200-2209
-
-
Fillion, D.1
Deraet, M.2
Holleran, B.J.3
Escher, E.4
-
24
-
-
0027340375
-
Sarl-p-benzoylphenylalanine-angiotensin, a new photoaffinity probe for selective labeling of the type 2 angiotensin receptor
-
Bosse, R.; Servant, G.; Zhou, L. M.; Boulay, G.; Guillemette, G.; Escher, E. Sarl-p-benzoylphenylalanine-angiotensin, a new photoaffinity probe for selective labeling of the type 2 angiotensin receptor. Regul Pept. 1993, 44, 215-223.
-
(1993)
Regul Pept.
, vol.44
, pp. 215-223
-
-
Bosse, R.1
Servant, G.2
Zhou, L.M.3
Boulay, G.4
Guillemette, G.5
Escher, E.6
-
25
-
-
23944441721
-
Importance of N-glycosylation positioning for cell-surface expression, targeting, affinity and quality control of the human ATI receptor
-
Lanctot, P. M.; Leclerc, P. C.; Clement, M.; Auger-Messier, M.; Escher, E.; Leduc, R.; Guillemette, G. Importance of N-glycosylation positioning for cell-surface expression, targeting, affinity and quality control of the human ATI receptor. Biochem. J. 2005, 390, 367-376.
-
(2005)
Biochem. J.
, vol.390
, pp. 367-376
-
-
Lanctot, P.M.1
Leclerc, P.C.2
Clement, M.3
Auger-Messier, M.4
Escher, E.5
Leduc, R.6
Guillemette, G.7
-
26
-
-
0029670965
-
The tyrosine within the NPXnY motif of the human angiotensin II type 1 receptor is involved in mediating signal transduction but is not essential for internalization
-
Laporte, S. A.; Servant, G.; Richard, D. E.; Escher, E.; Guillemette, G.; Leduc, R. The tyrosine within the NPXnY motif of the human angiotensin II type 1 receptor is involved in mediating signal transduction but is not essential for internalization. Mol Pharmacol. 1996, 49, 89-95.
-
(1996)
Mol Pharmacol.
, vol.49
, pp. 89-95
-
-
Laporte, S.A.1
Servant, G.2
Richard, D.E.3
Escher, E.4
Guillemette, G.5
Leduc, R.6
-
27
-
-
0025362615
-
Analysis of proteins and glycoproteins on blots
-
Bayer, E. A.; Ben-Hur, H.; Wilchek, M. Analysis of proteins and glycoproteins on blots. Methods Enzymol 1990, 184, 415-427.
-
(1990)
Methods Enzymol
, vol.184
, pp. 415-427
-
-
Bayer, E.A.1
Ben-Hur, H.2
Wilchek, M.3
-
28
-
-
0003084891
-
-
Springer: Berlin/Heidelberg
-
Durchschlag, H.; Christl, R.; Jaenicke, R. Progress in Colloid and Polymer Science; Springer: Berlin/Heidelberg, 1991; Vol 86, pp 41-56.
-
(1991)
Progress in Colloid and Polymer Science
, vol.86
, pp. 41-56
-
-
Durchschlag, H.1
Christl, R.2
Jaenicke, R.3
-
29
-
-
49349107302
-
Renin-angiotensin system revisited
-
Fyhrquist, F.; Saijonmaa, O. Renin-angiotensin system revisited. J Intern. Med. 2008, 264, 224-236.
-
(2008)
J Intern. Med.
, vol.264
, pp. 224-236
-
-
Fyhrquist, F.1
Saijonmaa, O.2
-
30
-
-
0031738230
-
Angiotensin charge relay system: Role of arginine
-
Pires, J. M.; Moore, G. J. Angiotensin charge relay system: role of arginine. Proc. West Pharmacol. Soc. 1998, 41, 197-199.
-
(1998)
Proc. West Pharmacol. Soc.
, vol.41
, pp. 197-199
-
-
Pires, J.M.1
Moore, G.J.2
-
31
-
-
0037179642
-
Angiotensin II vs its type i antagonists: Conformational requirements for receptor binding assessed from NMR spectroscopic and receptor docking experiments
-
Wilkes, B. C.; Masaro, L.; Schiller, P. W.; Carpenter, K. A. Angiotensin II vs its type I antagonists: conformational requirements for receptor binding assessed from NMR spectroscopic and receptor docking experiments. J. Med. Chem. 2002, 45, 4410-4418.
-
(2002)
J. Med. Chem.
, vol.45
, pp. 4410-4418
-
-
Wilkes, B.C.1
Masaro, L.2
Schiller, P.W.3
Carpenter, K.A.4
-
32
-
-
18144433890
-
The design and synthesis of a potent Angiotensin II cyclic analogue confirms the ring cluster receptor conformation of the hormone Angiotensin II
-
Matsoukas, J. M.; Polevaya, L.; Ancans, J.; Mavromoustakos, T.; Kolocouris, A.; Roumelioti, P.; Vlahakos, D. V.; Yamdagni, R.; Wu, Q.; Moore, G. J. The design and synthesis of a potent Angiotensin II cyclic analogue confirms the ring cluster receptor conformation of the hormone Angiotensin II. Bioorg. Med. Chem. 2000, 8, 1-10.
-
(2000)
Bioorg. Med. Chem.
, vol.8
, pp. 1-10
-
-
Matsoukas, J.M.1
Polevaya, L.2
Ancans, J.3
Mavromoustakos, T.4
Kolocouris, A.5
Roumelioti, P.6
Vlahakos, D.V.7
Yamdagni, R.8
Wu, Q.9
Moore, G.J.10
-
33
-
-
0033548623
-
Role of aromaticky of agonist switches of angiotensin II in the activation of the ATI receptor
-
Miura, S.; Feng, Y. H.; Husain, A.; Karnik, S. S. Role of aromaticky of agonist switches of angiotensin II in the activation of the ATI receptor. J. Biol. Chem. 1999, 274, 7103-7110.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7103-7110
-
-
Miura, S.1
Feng, Y.H.2
Husain, A.3
Karnik, S.S.4
-
34
-
-
0029878871
-
Tachyphylaxis to angiotensin II and [Phe4]-angiotensin II in the rat mesentery in vivo
-
Tofovic, S. P.; Jackson, E. K. Tachyphylaxis to angiotensin II and [Phe4]-angiotensin II in the rat mesentery in vivo. J. Pharmacol. Exp. Ther. 1996, 276, 13-20.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.276
, pp. 13-20
-
-
Tofovic, S.P.1
Jackson, E.K.2
-
35
-
-
0028676194
-
Receptor interactions of the position 4 side chains of angiotensin II analogues: Importance of aromatic ring quadrupole
-
Moore, G. J.; Ganter, R. C.; Matsoukas, J. M.; Hondrelis, J.; Agelis, G.; Barios, K.; Wilkinson, S.; Sandall, J.; Fowler, P. Receptor interactions of the position 4 side chains of angiotensin II analogues: importance of aromatic ring quadrupole. J. Mol. Recognit. 1994, 7, 251-256.
-
(1994)
J. Mol. Recognit.
, vol.7
, pp. 251-256
-
-
Moore, G.J.1
Ganter, R.C.2
Matsoukas, J.M.3
Hondrelis, J.4
Agelis, G.5
Barios, K.6
Wilkinson, S.7
Sandall, J.8
Fowler, P.9
-
36
-
-
0021343601
-
Angiotensin II: Dependence of hormone affinity on the electronegativity of a single side chain
-
Guillemette, G.; Bernier, M.; Parent, P.; Leduc, R.; Escher, E. Angiotensin II: dependence of hormone affinity on the electronegativity of a single side chain. J. Med. Chem. 1984, 27, 315-320.
-
(1984)
J. Med. Chem.
, vol.27
, pp. 315-320
-
-
Guillemette, G.1
Bernier, M.2
Parent, P.3
Leduc, R.4
Escher, E.5
-
37
-
-
0021798373
-
Studies on angiotensin II and analogs: Impact of substitution in position 8 on conformation and activity
-
Aumelas, A.; Sakarellos, C.; Lintner, K.; Fermandjian, S.; Khosla, M. C.; Smeby, R. R.; Bumpus, F. M. Studies on angiotensin II and analogs: impact of substitution in position 8 on conformation and activity. Proc. Natl. Acad. Sci. U.S.A. 1985, 82, 1881-1885.
-
(1985)
Proc. Natl. Acad. Sci. U.S.A.
, vol.82
, pp. 1881-1885
-
-
Aumelas, A.1
Sakarellos, C.2
Lintner, K.3
Fermandjian, S.4
Khosla, M.C.5
Smeby, R.R.6
Bumpus, F.M.7
-
38
-
-
33845199074
-
The active and the inactive form of the hAT1 receptor have an identical ligand-binding environment: An MPA study on a constitutively active angiotensin II receptor mutant
-
Clement, M.; Chamberland, C.; Perodin, J.; Leduc, R.; Guillemette, G.; Escher, E. The active and the inactive form of the hAT1 receptor have an identical ligand-binding environment: an MPA study on a constitutively active angiotensin II receptor mutant. J. Recept. Signal Transduct. Res. 2006, 26, 417-433.
-
(2006)
J. Recept. Signal Transduct. Res.
, vol.26
, pp. 417-433
-
-
Clement, M.1
Chamberland, C.2
Perodin, J.3
Leduc, R.4
Guillemette, G.5
Escher, E.6
-
39
-
-
2142717333
-
Mutagenesis of the ATI receptor reveals different binding modes of angiotensin II and [Sarl]-angiotensin II
-
Santos, E. L.; Pesquero, J. B.; Oliveira, L.; Paiva, A. C.; Costa-Neto, C. M. Mutagenesis of the ATI receptor reveals different binding modes of angiotensin II and [Sarl]-angiotensin II. Regul. Pept. 2004, 119, 183-188.
-
(2004)
Regul. Pept.
, vol.119
, pp. 183-188
-
-
Santos, E.L.1
Pesquero, J.B.2
Oliveira, L.3
Paiva, A.C.4
Costa-Neto, C.M.5
-
40
-
-
0027988149
-
Identification of peptide binding residues in the extracellular domains of the AT1 receptor
-
Hjorth, S. A.; Schambye, H. T.; Greenlee, W. J.; Schwartz, T. W. Identification of peptide binding residues in the extracellular domains of the AT1 receptor. J. Biol. Chem. 1994, 269, 30953-30959.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 30953-30959
-
-
Hjorth, S.A.1
Schambye, H.T.2
Greenlee, W.J.3
Schwartz, T.W.4
-
41
-
-
0037589024
-
Conformational features of a synthetic model of the first extracellular loop of the angiotensin II AT1A receptor
-
Nicastro, G.; Peri, F.; Franzoni, L.; de Chiara, C.; Sartor, G.; Spisni, A. Conformational features of a synthetic model of the first extracellular loop of the angiotensin II AT1A receptor. J. Pept. Sci. 2003, 9, 229-243.
-
(2003)
J. Pept. Sci.
, vol.9
, pp. 229-243
-
-
Nicastro, G.1
Peri, F.2
Franzoni, L.3
De Chiara, C.4
Sartor, G.5
Spisni, A.6
-
42
-
-
0037026868
-
Trifluoroethanol and binding to model membranes stabilize a predicted turn in a peptide corresponding to the first extracellular loop of the angiotensin II AT(1A) receptor
-
Salinas, R. K.; Shida, C. S.; Pertinhez, T. A.; Spisni, A.; Nakaie, C. R.; Paiva, A. C.; Schreier, S. Trifluoroethanol and binding to model membranes stabilize a predicted turn in a peptide corresponding to the first extracellular loop of the angiotensin II AT(1A) receptor. Biopolymers 2002, 65, 21-31.
-
(2002)
Biopolymers
, vol.65
, pp. 21-31
-
-
Salinas, R.K.1
Shida, C.S.2
Pertinhez, T.A.3
Spisni, A.4
Nakaie, C.R.5
Paiva, A.C.6
Schreier, S.7
-
43
-
-
33744959047
-
Genetic analysis of the first and third extracellular loops of the C5a receptor reveals an essential WXFG motif in the first loop
-
Klco, J. M.; Nikiforovich, G. V.; Baranski, T. J. Genetic analysis of the first and third extracellular loops of the C5a receptor reveals an essential WXFG motif in the first loop. J. Biol. Chem. 2006, 281, 12010-12019.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 12010-12019
-
-
Klco, J.M.1
Nikiforovich, G.V.2
Baranski, T.J.3
-
44
-
-
33644747561
-
Model of the whole rat ATI receptor and the ligand-binding site
-
Baleanu-Gogonea, C.; Karnik, S. Model of the whole rat ATI receptor and the ligand-binding site. J. Mol Model. 2006, 12, 325-337.
-
(2006)
J. Mol Model.
, vol.12
, pp. 325-337
-
-
Baleanu-Gogonea, C.1
Karnik, S.2
-
45
-
-
0036266161
-
Site-directed mutagenesis of the gerbil and human angiotensin II AT(1) receptors identifies amino acid residues attributable to the binding affinity for the nonpeptidic antagonist losartan
-
Hoe, K. L.; Saavedra, J. M. Site-directed mutagenesis of the gerbil and human angiotensin II AT(1) receptors identifies amino acid residues attributable to the binding affinity for the nonpeptidic antagonist losartan. Mol Pharmacol. 2002, 61, 1404-1415.
-
(2002)
Mol Pharmacol.
, vol.61
, pp. 1404-1415
-
-
Hoe, K.L.1
Saavedra, J.M.2
-
46
-
-
0037096137
-
Aliphatic amino acids in helix VI of the AT(I) receptor play a relevant role in agonist binding and activity
-
Correa, S. A.; Zalcberg, H.; Han, S. W.; Oliveira, L.; Costa-Neto, CM.; Paiva, A. C.; Shimuta, S. I. Aliphatic amino acids in helix VI of the AT(I) receptor play a relevant role in agonist binding and activity. Regul. Pept. 2002, 106, 33-38.
-
(2002)
Regul. Pept.
, vol.106
, pp. 33-38
-
-
Correa, S.A.1
Zalcberg, H.2
Han, S.W.3
Oliveira, L.4
Costa-Neto, C.M.5
Paiva, A.C.6
Shimuta, S.I.7
-
47
-
-
0036000558
-
Relevant role of Leu265 in helix VI of the angiotensin ATI receptor in agonist binding and activity
-
Correa, S. A.; Franca, L. P.; Costa-Neto, C. M.; Oliveira, L.; Paiva, A. C.; Shimuta, S. I. Relevant role of Leu265 in helix VI of the angiotensin ATI receptor in agonist binding and activity. Can. J. Physiol. Pharmacol. 2002, 80, 426-430.
-
(2002)
Can. J. Physiol. Pharmacol.
, vol.80
, pp. 426-430
-
-
Correa, S.A.1
Franca, L.P.2
Costa-Neto, C.M.3
Oliveira, L.4
Paiva, A.C.5
Shimuta, S.I.6
-
48
-
-
0034595571
-
Molecular cloning of a ferret angiotensin II AT(1) receptor reveals the importance of position 163 for Losartan binding
-
Gosselin, M. J.; Leclerc, P. C.; Auger-Messier, M.; Guillemette, G.; Escher, E.; Leduc, R. Molecular cloning of a ferret angiotensin II AT(1) receptor reveals the importance of position 163 for Losartan binding. Biochim. Biophys. Acta 2000, 1497, 94-102.
-
(2000)
Biochim. Biophys. Acta
, vol.1497
, pp. 94-102
-
-
Gosselin, M.J.1
Leclerc, P.C.2
Auger-Messier, M.3
Guillemette, G.4
Escher, E.5
Leduc, R.6
-
49
-
-
0033914026
-
Mutational analysis of the interaction of the N- And C-terminal ends of angiotensin II with the rat AT(1A) receptor
-
Costa-Neto, C. M.; Miyakawa, A. A.; Oliveira, L.; Hjorth, S. A.; Schwartz, T. W.; Paiva, A. C. Mutational analysis of the interaction of the N- and C-terminal ends of angiotensin II with the rat AT(1A) receptor. Br. J. Pharmacol. 2000, 130, 1263-1268.
-
(2000)
Br. J. Pharmacol.
, vol.130
, pp. 1263-1268
-
-
Costa-Neto, C.M.1
Miyakawa, A.A.2
Oliveira, L.3
Hjorth, S.A.4
Schwartz, T.W.5
Paiva, A.C.6
-
50
-
-
0031010320
-
A review of mutagenesis studies of angiotensin II type 1 receptor, the three-dimensional receptor model in search of the agonist and antagonist binding site and the hypothesis of a receptor activation mechanism
-
Inoue, Y.; Nakamura, N.; Inagami, T. A review of mutagenesis studies of angiotensin II type 1 receptor, the three-dimensional receptor model in search of the agonist and antagonist binding site and the hypothesis of a receptor activation mechanism. J. Hypertens. 1997, 15, 703-714.
-
(1997)
J. Hypertens.
, vol.15
, pp. 703-714
-
-
Inoue, Y.1
Nakamura, N.2
Inagami, T.3
-
51
-
-
0032520692
-
Survey of four different photoreactive moieties for DNA photoaffinity labeling of yeast RNA polymerase III transcription complexes
-
Tate, J. J.; Persinger, J.; Bartholomew, B. Survey of four different photoreactive moieties for DNA photoaffinity labeling of yeast RNA polymerase III transcription complexes. Nucleic Acids Res. 1998, 25, 1421-1426.
-
(1998)
Nucleic Acids Res.
, vol.25
, pp. 1421-1426
-
-
Tate, J.J.1
Persinger, J.2
Bartholomew, B.3
-
52
-
-
0001030243
-
Intrinsic reactivities of amino acids toward photoalkylation with benzophenone - A study preliminary to photolabelling of the transmembrane protein glycophorin A
-
Deseke, E.; Nakatami, Y.; Ourisson, G. Intrinsic reactivities of amino acids toward photoalkylation with benzophenone - a study preliminary to photolabelling of the transmembrane protein glycophorin A. Eur. J. Org. Chem. 1998, 243-251.
-
(1998)
Eur. J. Org. Chem.
, pp. 243-251
-
-
Deseke, E.1
Nakatami, Y.2
Ourisson, G.3
-
53
-
-
0030959062
-
Comparison of the photochemical behavior of four different photoactivatable probes
-
Weber, P. J.; Beck-Sickinger, A. G. Comparison of the photochemical behavior of four different photoactivatable probes. J. Pept. Res. 1997, 49, 375-383.
-
(1997)
J. Pept. Res.
, vol.49
, pp. 375-383
-
-
Weber, P.J.1
Beck-Sickinger, A.G.2
-
54
-
-
0028808348
-
Chemical reagents in photoaffinity labeling
-
Fleming, S. A. Chemical reagents in photoaffinity labeling. Tetrahedron 1995, 51, 12479-12520.
-
(1995)
Tetrahedron
, vol.51
, pp. 12479-12520
-
-
Fleming, S.A.1
-
55
-
-
36448995359
-
High-resolution crystal structure of an engineered human beta2-adrenergic G proteincoupled receptor
-
Cherezov, V.; Rosenbaum, D. M.; Hanson, M. A.; Rasmussen, S. G.; Thian, F. S.; Kobilka, T. S.; Choi, H. J.; Kuhn, P.; Weis, W. I.; Kobilka, B. K.; Stevens, R. C. High-resolution crystal structure of an engineered human beta2-adrenergic G proteincoupled receptor. Science 2007, 318, 1258-1265.
-
(2007)
Science
, vol.318
, pp. 1258-1265
-
-
Cherezov, V.1
Rosenbaum, D.M.2
Hanson, M.A.3
Rasmussen, S.G.4
Thian, F.S.5
Kobilka, T.S.6
Choi, H.J.7
Kuhn, P.8
Weis, W.I.9
Kobilka, B.K.10
Stevens, R.C.11
-
56
-
-
47049130668
-
Crystal structure of the ligand-free G-protein-coupled receptor opsin
-
Park, J. H.; Scheerer, P.; Hofmann, K. P.; Choe, H. W.; Ernst, O. P. Crystal structure of the ligand-free G-protein-coupled receptor opsin. Nature 2008, 454, 183-187.
-
(2008)
Nature
, vol.454
, pp. 183-187
-
-
Park, J.H.1
Scheerer, P.2
Hofmann, K.P.3
Choe, H.W.4
Ernst, O.P.5
-
57
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski, K.; Kumasaka, T.; Hori, T.; Behnke, C. A.; Motoshima, H.; Fox, B. A.; Le Trong, I.; Teller, D. C.; Okada, T.; Stenkamp, R. E.; Yamamoto, M.; Miyano, M. Crystal structure of rhodopsin: A G protein-coupled receptor. Science 2000, 289, 739-745.
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
Le Trong, I.7
Teller, D.C.8
Okada, T.9
Stenkamp, R.E.10
Yamamoto, M.11
Miyano, M.12
-
58
-
-
59649112109
-
Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation
-
Ahuja, S.; Hornak, V.; Yan, E. C.; Syrett, N.; Goncalves, J. A.; Hirshfeld, A.; Ziliox, M.; Sakmar, T. P.; Sheves, M.; Reeves, P. J.; Smith, S. O.; Eilers, M. Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation. Nat. Struct. Mol Biol. 2009, 16, 168-175.
-
(2009)
Nat. Struct. Mol Biol.
, vol.16
, pp. 168-175
-
-
Ahuja, S.1
Hornak, V.2
Yan, E.C.3
Syrett, N.4
Goncalves, J.A.5
Hirshfeld, A.6
Ziliox, M.7
Sakmar, T.P.8
Sheves, M.9
Reeves, P.J.10
Smith, S.O.11
Eilers, M.12
-
59
-
-
0347717582
-
The second extracellular loop of the dopamine D2 receptor lines the binding-site crevice
-
Shi, L.; Javitch, J. A. The second extracellular loop of the dopamine D2 receptor lines the binding-site crevice. Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 440-445.
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 440-445
-
-
Shi, L.1
Javitch, J.A.2
-
60
-
-
0036169280
-
The binding site of aminergic G proteincoupled receptors: The transmembrane segments and second extracellular loop
-
Shi, L.; Javitch, J. A. The binding site of aminergic G proteincoupled receptors: the transmembrane segments and second extracellular loop. Annu. Rev. Pharmacol. Toxicol. 2002, 42, 437-467.
-
(2002)
Annu. Rev. Pharmacol. Toxicol.
, vol.42
, pp. 437-467
-
-
Shi, L.1
Javitch, J.A.2
-
61
-
-
47949129742
-
Structure of a betal-adrenergic G-protein-coupled receptor
-
Warne, T.; Serrano-Vega, M. J.; Baker, J. G.; Moukhametzianov, R.; Edwards, P. C.; Henderson, R.; Leslie, A. G.; Tate, C. G.; Schertler, G. F. Structure of a betal-adrenergic G-protein-coupled receptor. Nature 2008, 454, 486-491.
-
(2008)
Nature
, vol.454
, pp. 486-491
-
-
Warne, T.1
Serrano-Vega, M.J.2
Baker, J.G.3
Moukhametzianov, R.4
Edwards, P.C.5
Henderson, R.6
Leslie, A.G.7
Tate, C.G.8
Schertler, G.F.9
-
62
-
-
36248970132
-
Crystal structure of the human beta2 adrenergic G-protein-coupled receptor
-
Rasmussen, S. G.; Choi, H. J.; Rosenbaum, D. M.; Kobilka, T. S.; Thian, F. S.; Edwards, P. C.; Burghammer, M.; Ratnala, V. R.; Sanishvili, R.; Fischetti, R. F.; Schertler, G. F.; Weis, W. I.; Kobilka, B. K. Crystal structure of the human beta2 adrenergic G-protein-coupled receptor. Nature 2007, 450, 383-387.
-
(2007)
Nature
, vol.450
, pp. 383-387
-
-
Rasmussen, S.G.1
Choi, H.J.2
Rosenbaum, D.M.3
Kobilka, T.S.4
Thian, F.S.5
Edwards, P.C.6
Burghammer, M.7
Ratnala, V.R.8
Sanishvili, R.9
Fischetti, R.F.10
Schertler, G.F.11
Weis, W.I.12
Kobilka, B.K.13
-
63
-
-
77949354649
-
Agonist activation of the angiotensin II type 1 receptor alters the spatial proximity of transmembrane domain 7 to the ligand binding pocket
-
San Diego, CA, USA, 2005, Blondelle, S. E., Ed.; American Peptide Society: San Diego
-
Fillion, D.; Guillemette, G.; Leduc, R.; Escher, E. In Agonist Activation of the Angiotensin II Type 1 Receptor Alters the Spatial Proximity of Transmembrane Domain 7 to the Ligand Binding Pocket, 19th American Peptide Society Symposium - Understanding Biology Using Peptides, San Diego, CA, USA, 2005, Blondelle, S. E., Ed.; American Peptide Society: San Diego, 2005; pp 357-358.
-
(2005)
19th American Peptide Society Symposium - Understanding Biology Using Peptides
, pp. 357-358
-
-
Fillion, D.1
Guillemette, G.2
Leduc, R.3
Escher, E.4
-
64
-
-
66349127459
-
Photoprobe peptides to map the interactions of angiotensin II with its receptor ATI
-
Fillion, D.; Guillemette, G.; Leduc, R.; Escher, E. Photoprobe peptides to map the interactions of angiotensin II with its receptor ATI. Adv. Exp. Med. Biol. 2009, 611, 329-330.
-
(2009)
Adv. Exp. Med. Biol.
, vol.611
, pp. 329-330
-
-
Fillion, D.1
Guillemette, G.2
Leduc, R.3
Escher, E.4
-
65
-
-
0036975624
-
Methionine proximity assay, a novel method for exploring peptide ligand-receptor interaction
-
Rihakova, L.; Deraet, M.; Auger-Messier, M.; Perodin, J.; Boucard, A. A.; Guillemette, G.; Leduc, R.; Lavigne, P.; Escher, E. Methionine proximity assay, a novel method for exploring peptide ligand-receptor interaction. J. Recept. Signal Transduct. Res. 2002, 22, 297-313.
-
(2002)
J. Recept. Signal Transduct. Res.
, vol.22
, pp. 297-313
-
-
Rihakova, L.1
Deraet, M.2
Auger-Messier, M.3
Perodin, J.4
Boucard, A.A.5
Guillemette, G.6
Leduc, R.7
Lavigne, P.8
Escher, E.9
-
67
-
-
0017874586
-
Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro3a, 6a-diphrenylglycoluril
-
Fraker, P. J.; Speck, J. C., Jr. Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro3a, 6a-diphrenylglycoluril. Biochem. Biophys. Res. Commun. 1978, 80, 849-857.
-
(1978)
Biochem. Biophys. Res. Commun.
, vol.80
, pp. 849-857
-
-
Fraker, P.J.1
Speck Jr., J.C.2
-
68
-
-
0026473061
-
Determination of radioligand specific activity using competition binding assays
-
Wiener, H. L.; Reith, M. E. Determination of radioligand specific activity using competition binding assays. Anal. Biochem. 1992, 207, 58-62.
-
(1992)
Anal. Biochem.
, vol.207
, pp. 58-62
-
-
Wiener, H.L.1
Reith, M.E.2
-
69
-
-
0027176673
-
Unknown radioligand specific activity
-
Wiener, H. L.; Reith, M. E. Unknown radioligand specific activity. Trends Pharmacol. Sci. 1993, 14, 294-296.
-
(1993)
Trends Pharmacol. Sci.
, vol.14
, pp. 294-296
-
-
Wiener, H.L.1
Reith, M.E.2
-
71
-
-
0023472472
-
Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa
-
Schagger, H.; von Jagow, G. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal. Biochem. 1987, 166, 368-379.
-
(1987)
Anal. Biochem.
, vol.166
, pp. 368-379
-
-
Schagger, H.1
Von Jagow, G.2
-
72
-
-
34248679167
-
Tricine-SDS-PAGE
-
Schagger, H. Tricine-SDS-PAGE. Nat. Protoc. 2006, 1, 16-22.
-
(2006)
Nat. Protoc.
, vol.1
, pp. 16-22
-
-
Schagger, H.1
|