A nonsense polymorphism (R392X) in TLR5 protects from obesity but predisposes to diabetes

Journal of Immunology

Volumn 190, Issue 7, 2013, Pages 3716-3720

  Al Daghri, Nasser M ^a,b   Clerici, Mario ^c,d   Al Attas, Omar ^a,b   Forni, Diego ^e   Alokail, Majed S ^a,b   Alkharfy, Khalid M ^a,b,f   Sabico, Shaun ^a   Mohammed, Abdul Khader ^a   Cagliani, Rachele ^e   Sironi, Manuela ^e  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

^c Don Carlo Gnocchi Organizzazione Non Lucrativa di Utilita' Sociale   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

^e Istituto di Ricerca e Cura A Carattere Scientifico Eugenio Medea   (Italy)

^f KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GLUCOSE; TOLL LIKE RECEPTOR 5;

ADULT; ALLELE; ARTICLE; BODY MASS; COHORT ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GENDER; GENETIC CORRELATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC SUSCEPTIBILITY; GENOTYPE; GLUCOSE BLOOD LEVEL; HETEROZYGOTE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONSENSE POLYMORPHISM; OBESITY; PRIORITY JOURNAL; PROTECTION; RISK FACTOR; SAUDI ARABIA; TLR5 GENE;

ADULT; ALLELES; BODY MASS INDEX; CODON, NONSENSE; CYTOKINES; DIABETES MELLITUS, TYPE 2; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; GLUCOSE INTOLERANCE; HUMANS; INFLAMMATION MEDIATORS; MALE; MIDDLE AGED; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; SEX FACTORS; TOLL-LIKE RECEPTOR 5;

EID: 84875461319     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1202936     Document Type: Article

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