Autophagy modulates borrelia burgdorferi-induced production of interleukin-1β (IL-1β)

Journal of Biological Chemistry

Volumn 288, Issue 12, 2013, Pages 8658-8666

  Buffen, Kathrin ^a   Oosting, Marije ^a   Mennens, Svenja ^a,b   Anand, Paras K ^b   Plantinga, Theo S ^a   Sturm, Patrick ^a   Van De Veerdonk, Frank L ^a   Van Der Meer, Jos W M ^a   Xavier, Ramnik J ^c   Kanneganti, Thirumala Devi ^b   Netea, Mihai G ^a   Joosten, Leo A B ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BORRELIA BURGDORFERI; CAUSATIVE AGENTS; CYTOKINE PRODUCTION; HUMAN PERIPHERAL BLOOD; INTRACELLULAR DEGRADATION; MRNA EXPRESSION; PRO-INFLAMMATORY CYTOKINES; REACTIVE OXYGEN SPECIES;

IMMUNOLOGY;

BACTERIA;

INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BORRELIA BURGDORFERI; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; IMMUNE SYSTEM; LYME DISEASE; NONHUMAN; PATHOGENESIS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM;

ADENINE; ANDROSTADIENES; AUTOPHAGY; BORRELIA BURGDORFERI; CASPASE 1; CELLS, CULTURED; ENZYME ACTIVATION; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; INTERLEUKIN-6; LEUKOCYTES, MONONUCLEAR; REACTIVE OXYGEN SPECIES; RECEPTORS, INTERLEUKIN-1; TUMOR NECROSIS FACTOR-ALPHA;

BORRELIA BURGDORFERI; BORRELIA BURGDORFERI GROUP; SPIROCHAETALES;

EID: 84875460335     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.412841     Document Type: Article

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