Characterization of macrophage phenotypes in three murine models of house-dust-mite-induced asthma

Mediators of Inflammation

Volumn 2013, Issue , 2013, Pages

  Draijer, Christina ^a,b   Robbe, Patricia ^b   Boorsma, Carian E ^a,b   Hylkema, MacHteld N ^b   Melgert, Barbro N ^a,b  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MARKER; IMMUNOGLOBULIN E; INTERFERON REGULATORY FACTOR 5; INTERLEUKIN 10; UNCLASSIFIED DRUG; YM1 PROTEIN; INTERFERON REGULATORY FACTOR; IRF5 PROTEIN, MOUSE;

ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DERMATOPHAGOIDES; DISEASE MODEL; DISEASE SEVERITY; EOSINOPHIL; EOSINOPHIL COUNT; FEMALE; HOUSE DUST ALLERGY; IMMUNOGLOBULIN BLOOD LEVEL; LUNG LAVAGE; LYMPHOCYTE COUNT; MACROPHAGE; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; ANIMAL; ASTHMA; BAGG ALBINO MOUSE; FLOW CYTOMETRY; IMMUNOLOGY; METABOLISM; PYROGLYPHIDAE;

MURINAE; MUS; PYROGLYPHIDAE;

ANIMALS; ASTHMA; FEMALE; FLOW CYTOMETRY; INTERFERON REGULATORY FACTORS; INTERLEUKIN-10; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; PHENOTYPE; PYROGLYPHIDAE;

EID: 84875427678     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2013/632049     Document Type: Article

References (47)

1. Barnes P. J., Immunology of asthma and chronic obstructive pulmonary disease. Nature Reviews Immunology 2008 8 3 183 192 2-s2.0-40049104892 10.1038/nri2254 (Pubitemid 351323287)
2. Anderson G. P., Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease. The Lancet 2008 372 9643 1107 1119 2-s2.0-52049087356 10.1016/S0140-6736(08)61452-X
3. Stout R. D., Suttles J., Functional plasticity of macrophages: reversible adaptation to changing microenvironments. Journal of Leukocyte Biology 2004 76 3 509 513 2-s2.0-4344706372 10.1189/jlb.0504272 (Pubitemid 39129080)
4. Mosser D. M., Edwards J. P., Exploring the full spectrum of macrophage activation. Nature Reviews Immunology 2008 8 12 958 969 2-s2.0-56749174940 10.1038/nri2448
5. Krausgruber T., Blazek K., Smallie T., Alzabin S., Lockstone H., Sahgal N., Hussell T., Feldmann M., Udalova I. A., IRF5 promotes inflammatory macrophage polarization and T H1-TH17 responses. Nature Immunology 2011 12 3 231 238 2-s2.0-79951671510 10.1038/ni.1990
6. Kreider T., Anthony R. M., Urban Jr J. F., Gause W. C., Alternatively activated macrophages in helminth infections. Current Opinion in Immunology 2007 19 448 453 10.1016/j.coi.2007.07.002 (Pubitemid 47299196)
7. Martinez F. O., Helming L., Gordon S., Alternative activation of macrophages: an immunologic functional perspective. Annual Reviews 2009 27 451 483
8. Nair M. G., Cochrane D. W., Allen J. E., Macrophages in chronic type 2 inflammation have a novel phenotype characterized by the abundant expression of Ym1 and Fizz1 that can be partly replicated in vitro. Immunology Letters 2003 85 2 173 180 2-s2.0-0037460123 10.1016/S0165-2478(02)00225-0 (Pubitemid 36071573)
9. Peters-Golden M., The alveolar macrophage: the forgotten cell in asthma. American Journal of Respiratory Cell and Molecular Biology 2004 31 1 3 7 2-s2.0-3042838551 10.1165/rcmb.f279 (Pubitemid 38888032)
10. Moreira A. P., Hogaboam C. M., Macrophages in allergic asthma: fine-tuning their pro- and anti-inflammatory actions for disease resolution. Journal of Interferon and Cytokine Research 2011 31 6 485 491 2-s2.0-79958228941 10.1089/jir.2011.0027
11. Dasgupta P., Keegan A. D., Contribution of alternatively activated macrophages to allergic lung Inflammation: a tale of mice and men. Journal of Innate Immunity 2012 4 5-6 478 488
12. Yang M., Kumar R. K., Hansbro P. M., Foster P. S., Emerging roles of pulmonary macrophages in driving the development of severe asthma. Journal of Leukocyte Biology 2012 91 557 569 10.1189/jlb.0711357
13. Chang Y. S., Kim Y. K., Bahn J. W., Kim S. H., Park H. W., Kim T. B., Cho S. H., Min K. U., Kim Y. Y., Comparison of asthma phenotypes using different sensitizing protocols in mice. Korean Journal of Internal Medicine 2005 20 2 152 158 2-s2.0-25144507656
14. Nials A. T., Uddin S., Mouse models of allergic asthma: acute and chronic allergen challenge. Disease Models and Mechanisms 2008 1 4-5 213 220 2-s2.0-64249119491 10.1242/dmm.000323
15. Hammad H., Plantinga M., Deswarte K., Pouliot P., Willart M. A. M., Kool M., Muskens F., Lambrecht B. N., Inflammatory dendritic cells-not basophils-are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen. The Journal of Experimental Medicine 2010 207 2097 2111 10.1084/jem.20101563
16. Gregory L. G., Mathie S. A., Walker S. A., Pegorier S., Jones C. P., Lloyd C. M., Overexpression of Smad2 drives house dust mite-mediated airway remodeling and airway hyperresponsiveness via activin and IL-25. American Journal of Respiratory and Critical Care Medicine 2010 182 2 143 154 2-s2.0-77956628834 10.1164/rccm.200905-0725OC
17. + non-migratory myeloid cells suppress Th2 effector function in the lung. Mucosal Immunology 2010 3 6 578 593 2-s2.0-77958166370 10.1038/mi.2010.41
18. Blacquière M. J., Timens W., Melgert B. N., Geerlings M., Postma D. S., Hylkema M. N., Maternal smoking during pregnancy induces airway remodelling in mice offspring. European Respiratory Journal 2009 33 5 1133 1140 2-s2.0-66749146655 10.1183/09031936.00129608
19. Melgert B. N., Oriss T. B., Qi Z., Dixon-McCarthy B., Geerlings M., Hylkema M. N., Ray A., Macrophages: regulators of sex differences in asthma? American Journal of Respiratory Cell and Molecular Biology 2010 42 5 595 603 2-s2.0-77951634926 10.1165/rcmb.2009-0016OC
20. Melgert B. N., Ten Hacken N. H., Rutgers B., Timens W., Postma D. S., Hylkema M. N., More alternative activation of macrophages in lungs of asthmatic patients. Journal of Allergy and Clinical Immunology 2011 127 3 831 833 2-s2.0-79952316010 10.1016/j.jaci.2010.10.045
21. Abbas A. K., Lichtman A. H., Pillai S., Cellular and Molecular Immunology 2011 Philadelphia, Pa, USA Elsevier Saunders
22. Raes G., de Baetselier P., Noël W., Beschin A., Brombacher F., Gholamreza H. G., Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages. Journal of Leukocyte Biology 2002 71 4 597 602 2-s2.0-0036553909
23. Loke P., Nair M. G., Parkinson J., Guiliano D., Blaxter M., Allen J. E., IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype. BMC Immunology 2002 3, article 7 2-s2.0-0242421851 10.1186/1471-2172-3-7 (Pubitemid 38692919)
24. Welch J. S., Escoubet-Lozach L., Sykes D. B., Liddiard K., Greaves D. R., Glass C. K., TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism. Journal of Biological Chemistry 2002 277 45 42821 42829 2-s2.0-0037044580 10.1074/jbc.M205873200 (Pubitemid 35285658)
25. Bastos K. R. B., Alvarez J. M., Marinho C. R. F., Rizzo L. V., Lima M. R. D., Macrophages from IL-12p40-deficient mice have a bias toward the M2 activation profile. Journal of Leukocyte Biology 2002 71 271 278
26. Sindrilaru A., Peters T., Wieschalka S., Baican C., Baican A., Peter H., Hainzl A., Schatz S., Qi Y., Schlecht A., Weiss J. M., Wlaschek M., Sunderkötter C., Scharffetter-Kochanek K., An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. Journal of Clinical Investigation 2011 121 3 985 997 2-s2.0-79952135247 10.1172/JCI44490
27. Nagata M., Inflammatory cells and oxygen radicals. Current Drug Targets 2005 4 4 503 504 2-s2.0-22944448999 10.2174/1568010054526322 (Pubitemid 41052417)
28. Chupp G. L., Lee C. G., Jarjour N., Shim Y. M., Holm C. T., He S., Dziura J. D., Reed J., Coyle A. J., Kiener P., Cullen M., Grandsaigne M., Dombret M. C., Aubier M., Pretolani M., Elias J. A., A chitinase-like protein in the lung and circulation of patients with severe asthma. The New England Journal of Medicine 2007 357 20 2016 2027 2-s2.0-36148981436 10.1056/NEJMoa073600 (Pubitemid 350106709)
29. Owhashi M., Arita H., Hayai N., Identification of a novel eosinophil chemotactic cytokine (ECF-L) as a chitinase family protein. Journal of Biological Chemistry 2000 275 2 1279 1286 2-s2.0-0033964511 10.1074/jbc.275.2. 1279 (Pubitemid 30051182)
30. Chang N. C. A., Hung S. I., Hwa K. Y., Kato I., Chen J. E., Liu C. H., Chang A. C., A macrophage protein, Ym1, transiently expressed during inflammation is a novel mammalian lectin. Journal of Biological Chemistry 2001 276 20 17497 17506 2-s2.0-0035907263 10.1074/jbc.M010417200
31. Voehringer D., van Rooijen N., Locksley R. M., Eosinophils develop in distinct stages and are recruited to peripheral sites by alternatively activated macrophages. Journal of Leukocyte Biology 2007 81 6 1434 1444 2-s2.0-34249746235 10.1189/jlb.1106686 (Pubitemid 46827966)
32. + regulatory T cells induce alternative activation of human monocytes/macrophages. Proceedings of the National Academy of Sciences of the United States of America 2007 104 49 19446 19451 2-s2.0-37649015079 10.1073/pnas.0706832104
33. + macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation. BMC Immunology 2012 13, articel 6
34. Nieuwenhuizen N. E., Kirstein F., Jayakumar J., Emedi B., Hurdayal R., Horsnell W. G. C., Lopata A. L., Brombacher F., Allergic airway disease is unaffected by the absence of IL-4Ra-dependent alternatively activated macrophages. The Journal of Allergy and Clinical Immunology 2012 130 3 743.e8 750.e8 10.1016/j.jaci.2012.03.011
35. Korf J. E., Pynaert G., Tournoy K., Boonefaes T., Van Oosterhout A., Ginneberge D., Haegeman A., Verschoor J. A., De Baetselier P., Grooten J., Macrophage reprogramming by mycolic acid promotes a tolerogenic response in experimental asthma. American Journal of Respiratory and Critical Care Medicine 2006 174 2 152 160 2-s2.0-33745761198 10.1164/rccm.200507-1175OC (Pubitemid 44015388)
36. Tang C., Inman M. D., van Rooijen N., Yang P., Shen H., Matsumoto K., O'Byrne P. M., Th type 1-stimulating activity of lung macrophages inhibits Th2-mediated allergic airway inflammation by an IFN- γ -dependent mechanism. Journal of Immunology 2001 166 3 1471 1481 2-s2.0-0035253346 (Pubitemid 32114625)
37. Goleva E., Hauk P. J., Hall C. F., Liu A. H., Riches D. W. H., Martin R. J., Leung D. Y. M., Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages. Journal of Allergy and Clinical Immunology 2008 122 3 550.e3 559.e3 2-s2.0-50649101494 10.1016/j.jaci.2008.07. 007
38. Ten Hacken N. H. T., Oosterhoff Y., Kauffman H. F., Guevarra L., Satoh T., Tollerud D. J., Postma D. S., Elevated serum interferon- γ in atopic asthma correlates with increased airways responsiveness and circadian peak expiratory flow variation. European Respiratory Journal 1998 11 2 312 316 2-s2.0-0031911281 10.1183/09031936.98.11020312 (Pubitemid 28108341)
39. Wang C., Rose-Zerilli M. J., Koppelman G. H., Sandling J. K., Holloway J. W., Postma D. S., Holgate S. T., Bours V., Syvänen A.-C, Dideberg V., Evidence of association between interferon regulatory factor 5 polymorphisms and asthma. Gene Gene 2012 504 220 225
40. Meyts I., Hellings P. W., Hens G., Vanaudenaerde B. M., Verbinnen B., Heremans H., Matthys P., Bullens D. M., Overbergh L., Mathieu C., De Boeck K., Ceuppens J. L., IL-12 contributes to allergen-induced airway inflammation in experimental asthma. Journal of Immunology 2006 177 9 6460 6470 2-s2.0-33750367858 (Pubitemid 44628865)
41. Bedoret D., Wallemacq H., Marichal T., Desmet C., Calvo F. Q., Henry E., Closset R., Dewals B., Thielen C., Gustin P., De Leval L., Van Rooijen N., Le Moine A., Vanderplasschen A., Cataldo D., Drion P. V., Moser M., Lekeux P., Bureau F., Lung interstitial macrophages alter dendritic cell functions to prevent airway allergy in mice. Journal of Clinical Investigation 2009 119 12 3723 3738 2-s2.0-72849113090 10.1172/JCI39717
42. Maneechotesuwan K., Supawita S., Kasetsinsombat K., Wongkajornsilp A., Barnes P. J., Sputum indoleamine-2, 3-dioxygenase activity is increased in asthmatic airways by using inhaled corticosteroids. Journal of Allergy and Clinical Immunology 2008 121 1 43 50 2-s2.0-38149085198 10.1016/j.jaci.2007.10. 011
43. John M., Lim S., Seybold J., Jose P., Robichaud A., O'Connor B., Barnes P. J., Chung K. F., Inhaled corticosteroids increase interleukin-10 but reduce macrophage inflammatory protein-1 granulocyte-macrophage colony-stimulating factor, and interferon- γ release from alveolar macrophages in asthma. American Journal of Respiratory and Critical Care Medicine 1998 157 1 256 262 2-s2.0-0031943945 (Pubitemid 28071290)
44. Fitzpatrick A. M., Higgins M., Holguin F., Brown L. A. S., Teague W. G., The molecular phenotype of severe asthma in children. Journal of Allergy and Clinical Immunology 2010 125 4 851.e18 857.e18 2-s2.0-77950215411 10.1016/j.jaci.2010.01.048
45. Almqvist C., Worm M., Leynaert B., Impact of gender on asthma in childhood and adolescence: a GA 2LEN review. Allergy 2008 63 1 47 57 2-s2.0-36649001609 10.1111/j.1398-9995.2007.01524.x (Pubitemid 350198234)
46. Melgert B. N., Postma D. S., Kuipers I., Geerlings M., Luinge M. A., van der Strate B. W. A., Kerstjens H. A. M., Timens W., Hylkema M. N., Female mice are more susceptible to the development of allergic airway inflammation than male mice. Clinical and Experimental Allergy 2005 35 11 1496 1503 2-s2.0-33645223560 10.1111/j.1365-2222.2005.02362.x
47. Melgert B. N., Ray A., Hylkema M. N., Timens W., Postma D. S., Are there reasons why adult asthma is more common in females? Current Allergy and Asthma Reports 2007 7 2 143 150 2-s2.0-34248349935 10.1007/s11882-007-0012-4 (Pubitemid 46736336)