메뉴 건너뛰기




Volumn 10, Issue 1, 2013, Pages 11-18

Boronic acid based inhibitors of autotaxin: Understanding their biological role in terms of quantitative structure activity relationships (QSAR)

Author keywords

Boronic Acid based Autotaxin Inhibitors; Hydrophobicity; Molar Refractivity; QSAR

Indexed keywords

AUTOTAXIN; BORONIC ACID DERIVATIVE; HA 155; LYSOPHOSPHATIDIC ACID; LYSOPHOSPHATIDYLCHOLINE; PHOSPHODIESTERASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 84875420342     PISSN: 15701808     EISSN: 1875628X     Source Type: Journal    
DOI: 10.2174/157018013804142483     Document Type: Article
Times cited : (4)

References (44)
  • 3
    • 0037131366 scopus 로고    scopus 로고
    • Identification of human plasma lysophospholipase d, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase
    • (c) Tokumura, A.; Majima, E.; Kariya, Y.; Tominaga, K.; Kogure, K.; Yasuda, K.; Fukuzawa, K., Identification of Human Plasma Lysophospholipase D, a Lysophosphatidic Acid-producing Enzyme, as Autotaxin, a Multifunctional Phosphodiesterase. Journal of Biological Chemistry 2002, 277(42), 39436-39442;
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.42 , pp. 39436-39442
    • Tokumura, A.1    Majima, E.2    Kariya, Y.3    Tominaga, K.4    Kogure, K.5    Yasuda, K.6    Fukuzawa, K.7
  • 5
    • 0042887042 scopus 로고    scopus 로고
    • The emerging role of lysophosphatidic acid in cancer
    • (a) Mills, G. B.; Moolenaar, W. H., The emerging role of lysophosphatidic acid in cancer. Nat Rev Cancer 2003, 3 (8), 582-591;
    • (2003) Nat Rev Cancer , vol.3 , Issue.8 , pp. 582-591
    • Mills, G.B.1    Moolenaar, W.H.2
  • 6
    • 0035025354 scopus 로고    scopus 로고
    • Physiological responses to lysophosphatidic acid and related glycero-phospholipids
    • (b) Tigyi, G., Physiological responses to lysophosphatidic acid and related glycero-phospholipids. Prostaglandins & Other Lipid Mediators 2001, 64(1-4), 47-62.
    • (2001) Prostaglandins & Other Lipid Mediators , vol.64 , Issue.1-4 , pp. 47-62
    • Tigyi, G.1
  • 10
    • 0038487319 scopus 로고    scopus 로고
    • Lysophosphatidic acid signaling: How a small lipid does big things
    • (a) Luquain, C.; Sciorra, V. A.; Morris, A. J., Lysophosphatidic acid signaling: how a small lipid does big things. Trends in biochemical sciences 2003, 28(7), 377-383;
    • (2003) Trends in Biochemical Sciences , vol.28 , Issue.7 , pp. 377-383
    • Luquain, C.1    Sciorra, V.A.2    Morris, A.J.3
  • 11
    • 34247534260 scopus 로고    scopus 로고
    • Regulation and biological activities of the autotaxin-LPA axis
    • (b) van Meeteren, L. A.; Moolenaar, W. H., Regulation and biological activities of the autotaxin-LPA axis. Progress in Lipid Research 2007, 46(2), 145-160.
    • (2007) Progress in Lipid Research , vol.46 , Issue.2 , pp. 145-160
    • Van Meeteren, L.A.1    Moolenaar, W.H.2
  • 12
    • 33845343972 scopus 로고    scopus 로고
    • Of spiders and crabs: The emergence of lysophospholipids and their metabolic pathways as targets for therapy in cancer
    • (a) Murph, M.; Tanaka, T.; Liu, S.; Mills, G. B., Of Spiders and Crabs: The Emergence of Lysophospholipids and Their Metabolic Pathways as Targets for Therapy in Cancer. Clinical Cancer Research 2006, 12(22), 6598-6602;
    • (2006) Clinical Cancer Research , vol.12 , Issue.22 , pp. 6598-6602
    • Murph, M.1    Tanaka, T.2    Liu, S.3    Mills, G.B.4
  • 18
    • 35448975763 scopus 로고    scopus 로고
    • α-substituted phosphonate analogues of lysophosphatidic acid (lpa) selectively inhibit production and action of lpa
    • (c) Jiang, G.; Xu, Y.; Fujiwara, Y.; Tsukahara, T.; Tsukahara, R.; Gajewiak, J.; Tigyi, G.; Prestwich, G. D., α-Substituted Phosphonate Analogues of Lysophosphatidic Acid (LPA) Selectively Inhibit Production and Action of LPA. ChemMedChem 2007, 2(5), 679-690;
    • (2007) ChemMedChem , vol.2 , Issue.5 , pp. 679-690
    • Jiang, G.1    Xu, Y.2    Fujiwara, Y.3    Tsukahara, T.4    Tsukahara, R.5    Gajewiak, J.6    Tigyi, G.7    Prestwich, G.D.8
  • 19
    • 35548986631 scopus 로고    scopus 로고
    • Inhibition of lysophospholipase d activity by unsaturated lysophosphatidic acids or seed extracts containing 1-linoleoyl and 1-oleoyl lysophosphatidic acid
    • (d) Liu, X.-W.; Sok, D.-E.; Yook, H.-S.; Sohn, C.-B.; Chung, Y.-J.; Kim, M. R., Inhibition of Lysophospholipase D Activity by Unsaturated Lysophosphatidic Acids or Seed Extracts Containing 1-Linoleoyl and 1-Oleoyl Lysophosphatidic Acid. Journal of Agricultural and Food Chemistry 2007, 55(21), 8717-8722.
    • (2007) Journal of Agricultural and Food Chemistry , vol.55 , Issue.21 , pp. 8717-8722
    • Liu, X.-W.1    Sok, D.-E.2    Yook, H.-S.3    Sohn, C.-B.4    Chung, Y.-J.5    Kim, M.R.6
  • 22
    • 45549085705 scopus 로고    scopus 로고
    • Synthesis, pharmacology, and cell biology of sn-2-aminooxy analogues of lysophosphatidic acid
    • (b) Gajewiak, J.; Tsukahara, R.; Fujiwara, Y.; Tigyi, G.; Prestwich, G. D., Synthesis, Pharmacology, and Cell Biology of sn-2-Aminooxy Analogues of Lysophosphatidic Acid. Organic Letters 2008, 10(6), 1111-1114;
    • (2008) Organic Letters , vol.10 , Issue.6 , pp. 1111-1114
    • Gajewiak, J.1    Tsukahara, R.2    Fujiwara, Y.3    Tigyi, G.4    Prestwich, G.D.5
  • 23
    • 45049086146 scopus 로고    scopus 로고
    • Anticancer activity of FTY720: Phosphorylated FTY720 inhibits autotaxin, a metastasis-enhancing and angiogenic lysophospholipase D
    • (c) van Meeteren, L. A.; Brinkmann, V.; Saulnier-Blache, J. S.; Lynch, K. R.; Moolenaar, W. H., Anticancer activity of FTY720: Phosphorylated FTY720 inhibits autotaxin, a metastasis-enhancing and angiogenic lysophospholipase D. Cancer letters 2008, 266(2), 203-208.
    • (2008) Cancer Letters , vol.266 , Issue.2 , pp. 203-208
    • Van Meeteren, L.A.1    Brinkmann, V.2    Saulnier-Blache, J.S.3    Lynch, K.R.4    Moolenaar, W.H.5
  • 26
    • 0019867976 scopus 로고
    • The physicochemical approach to drug design and discovery (QSAR)
    • (a) Hansch, C., The physicochemical approach to drug design and discovery (QSAR). Drug Development Research 1981, 1 (4), 267-309;
    • (1981) Drug Development Research , vol.1 , Issue.4 , pp. 267-309
    • Hansch, C.1
  • 27
    • 34447521097 scopus 로고
    • Correlation of biological activity of phenoxyacetic acids with hammett substituent constants and partition coefficients
    • (b) Hansch, C.; Maloney, P. P.; Fujita, T.; Muir, R. M., Correlation of Biological Activity of Phenoxyacetic Acids with Hammett Substituent Constants and Partition Coefficients. Nature 1962, 194(4824), 178-180;
    • (1962) Nature , vol.194 , Issue.4824 , pp. 178-180
    • Hansch, C.1    Maloney, P.P.2    Fujita, T.3    Muir, R.M.4
  • 29
    • 79955404831 scopus 로고    scopus 로고
    • BioByte Corporation, 201 W Fourth str., Suite # 204, Claremont, CA 91711-4707, USA;
    • (a) BioByte Corporation, C-QSAR database, 201 W Fourth str., Suite # 204, Claremont, CA 91711-4707, USA;
    • C-QSAR Database
  • 30
    • 84875468869 scopus 로고    scopus 로고
    • (b) www.biobyte.com.
  • 32
    • 4644228478 scopus 로고    scopus 로고
    • Comparative quantitative structure-activity relationship studies (qsar) on non-benzodiazepine compounds binding to benzodiazepine receptor (bzr)
    • (a) Hadjipavlou-Litina, D.; Garg, R.; Hansch, C., Comparative Quantitative Structure-Activity Relationship Studies (QSAR) on Non-Benzodiazepine Compounds Binding to Benzodiazepine Receptor (BzR). Chemical Reviews 2004, 104(9), 3751-3794;
    • (2004) Chemical Reviews , vol.104 , Issue.9 , pp. 3751-3794
    • Hadjipavlou-Litina, D.1    Garg, R.2    Hansch, C.3
  • 33
    • 0000540642 scopus 로고
    • Quantitative Structure-Activity Relationships of the Benzodiazepines. A Review and Reevaluation
    • (b) Hadjipavlou-Litina, D.; Hansch, C., Quantitative Structure-Activity Relationships of the Benzodiazepines. A Review and Reevaluation. Chemical Reviews 1994, 94(6), 1483-1505;
    • (1994) Chemical Reviews , vol.94 , Issue.6 , pp. 1483-1505
    • Hadjipavlou-Litina, D.1    Hansch, C.2
  • 34
    • 65649105091 scopus 로고    scopus 로고
    • Chalcones in cancer: Understanding their role in terms of QSAR
    • (c) Katsori, A. M.; Hadjipavlou-Litina, D., Chalcones in cancer: understanding their role in terms of QSAR. Curr Med Chem 2009, 16 (9), 1062-81;
    • (2009) Curr Med Chem , vol.16 , Issue.9 , pp. 1062-1081
    • Katsori, A.M.1    Hadjipavlou-Litina, D.2
  • 35
    • 84055190790 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors (HDACIs). Structure - Activity relationships: History and new QSAR perspectives
    • (d) Pontiki, E.; Hadjipavlou-Litina, D., Histone deacetylase inhibitors (HDACIs). Structure - activity relationships: history and new QSAR perspectives. Medicinal Research Reviews 2012, 32 (1), 1-165.
    • (2012) Medicinal Research Reviews , vol.32 , Issue.1 , pp. 1-165
    • Pontiki, E.1    Hadjipavlou-Litina, D.2
  • 37
    • 84862667721 scopus 로고    scopus 로고
    • An historic perspective of proteasome inhibition
    • (b) Esseltine, D.-L.; Mulligan, G., An Historic Perspective of Proteasome Inhibition. Seminars in hematology 2012, 49(3), 196-206.
    • (2012) Seminars in Hematology , vol.49 , Issue.3 , pp. 196-206
    • Esseltine, D.-L.1    Mulligan, G.2
  • 38
    • 20544451024 scopus 로고    scopus 로고
    • An approach toward the problem of outliers in QSAR
    • Verma, R. P.; Hansch, C., An approach toward the problem of outliers in QSAR. Bioorganic & Medicinal Chemistry 2005, 13(15), 4597-4621.
    • (2005) Bioorganic & Medicinal Chemistry , vol.13 , Issue.15 , pp. 4597-4621
    • Verma, R.P.1    Hansch, C.2
  • 39
    • 84987100711 scopus 로고
    • Crossvalidation bootstrapping and partial least squares compared with multiple regression in conventional qsar studies
    • Cramer, R. D.; Bunce, J. D.; Patterson, D. E.; Frank, I. E., Crossvalidation, Bootstrapping, and Partial Least Squares Compared with Multiple Regression in Conventional QSAR Studies. Quantitative Structure-Activity Relationships 1988, 7 (1), 18-25.
    • (1988) Quantitative Structure-Activity Relationships , vol.7 , Issue.1 , pp. 18-25
    • Cramer, R.D.1    Bunce, J.D.2    Patterson, D.E.3    Frank, I.E.4
  • 41
    • 25444533087 scopus 로고    scopus 로고
    • Nonsteroidal anti- inflammatory drugs (nsaids): A comparative qsar study
    • (b) Michaelidou, A. S.; Hadjipavlou-Litina, D., Nonsteroidal Anti- Inflammatory Drugs (NSAIDs): A Comparative QSAR Study. Chemical Reviews 2005, 105(9), 3235-3271;
    • (2005) Chemical Reviews , vol.105 , Issue.9 , pp. 3235-3271
    • Michaelidou, A.S.1    Hadjipavlou-Litina, D.2
  • 42
    • 33748605052 scopus 로고    scopus 로고
    • Anti-cancer activities of 1,4-naphthoquinones: A QSAR study
    • (c) Verma, R. P., Anti-cancer activities of 1,4-naphthoquinones: a QSAR study. Anticancer Agents Med Chem 2006, 6(5), 489-99.
    • (2006) Anticancer Agents Med Chem , vol.6 , Issue.5 , pp. 489-499
    • Verma, R.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.