The molecular basis of iron-induced oligomerization of frataxin and the role of the ferroxidation reaction in oligomerization

Journal of Biological Chemistry

Volumn 288, Issue 12, 2013, Pages 8156-8167

  Söderberg, Christopher A G ^a   Rajan, Sreekanth ^a   Shkumatov, Alexander V ^b,d   Gakh, Oleksandr ^c   Schaefer, Susanne ^a   Ahlgren, Eva Christina ^a   Svergun, Dmitri I ^b   Isaya, Grazia ^c   Al Karadaghi, Salam ^a  

^a LUND UNIVERSITY   (Sweden)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c MAYO CLINIC   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE FUNCTIONS; HEME BIOSYNTHESIS; INTERACTION SITE; IRON-SULFUR CLUSTERS; MITOCHONDRIAL PROTEIN; SMALL ANGLE X-RAY SCATTERING; SOLUTION STRUCTURES; X-RAY CRYSTALLOGRAPHIC STRUCTURES;

BIOCHEMISTRY; BIOSYNTHESIS; DETOXIFICATION; ESCHERICHIA COLI; IRON; OLIGOMERIZATION; PROTEINS; REPAIR; X RAY CRYSTALLOGRAPHY; X RAYS;

OLIGOMERS;

FRATAXIN; IRON; PROTEIN CYAY; PROTEIN YFH1; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; ESCHERICHIA COLI; FERROXIDATION; MOLECULAR INTERACTION; MOLECULAR MECHANICS; OLIGOMERIZATION; OXIDATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN STRUCTURE; X RAY CRYSTALLOGRAPHY; YEAST;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; BINDING SITES; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI PROTEINS; IRON; IRON-BINDING PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; SCATTERING, SMALL ANGLE; THERMODYNAMICS;

ESCHERICHIA COLI;

EID: 84875410144     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.442285     Document Type: Article

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