Homotrimeric macrophage migration inhibitory factor (MIF) drives inflammatory responses in the corneal epithelium by promoting caveolin-rich platform assembly in response to infection

Journal of Biological Chemistry

Volumn 288, Issue 12, 2013, Pages 8269-8278

  Reidy, Thomas ^a   Rittenberg, Alexander ^a   Dwyer, Markryan ^a   D'Ortona, Samantha ^a   Pier, Gerald ^a   Gadjeva, Mihaela ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-INFLAMMATORY AGENTS; FUNCTIONAL ACTIVITIES; FUNCTIONAL PROPERTIES; INFLAMMATORY RESPONSE; INFLAMMATORY SIGNALING; MIGRATION INHIBITORY FACTORS; PSEUDOMONAS AERUGINOSA; THERAPEUTIC BENEFITS;

DRUG PRODUCTS; MAMMALS; OLIGOMERS; PATHOLOGY; TISSUE;

MACROPHAGES;

CAVEOLIN; INTERLEUKIN 8; MACROPHAGE MIGRATION INHIBITION FACTOR; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORNEA CELL; CORNEA EPITHELIUM; CORRELATIONAL STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE SEVERITY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INFLAMMATION; KERATITIS; LIPID RAFT; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; CAVEOLINS; CELLS, CULTURED; CONJUNCTIVITIS, BACTERIAL; EPITHELIUM, CORNEAL; HUMANS; INFLAMMATION MEDIATORS; INTERLEUKIN-8; MACROPHAGE MIGRATION-INHIBITORY FACTORS; MAP KINASE SIGNALING SYSTEM; MEMBRANE MICRODOMAINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; PRIMARY CELL CULTURE; PROTEIN STRUCTURE, QUATERNARY; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

BACTERIA (MICROORGANISMS); MUS; PSEUDOMONAS AERUGINOSA;

EID: 84875408873     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.351064     Document Type: Article

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