Synthesis and in vitro antitumor and antimicrobial activity of some 2,3-diaryl-7-methyl-4,5,6,7-tetrahydroindazole and 3,3a,4,5,6,7- hexahydroindazole derivatives

Journal of Enzyme Inhibition and Medicinal Chemistry

Volumn 28, Issue 3, 2013, Pages 495-508

  Faidallah, Hassan M ^a   Khan, Khalid A ^a   Rostom, Sherif A F ^a,b   Asiri, Abdullah M ^a  

^a KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^b Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

Antitumor and antimicrobial activity; Benzenesulfonylureas; Hexahydroindazoles; Tetrahydroindazoles; Thioureas

Indexed keywords

2 [4 (7 METHYL 3 ARYL 3,3A,4,5,6,7 HEXAHYDROINDAZOL 2 YL)BENZENESULFONYLIMINO] 4 PHENYL 3 SUBSTITUTED THIAZOLINE DERIVATIVE; 2,3 DIARYL 7 METHYL 4,5,6,7 TETRAHYDROINDAZOLE DERIVATIVE; 3,3A,4,5,6,7 HEXAHYDROINDAZOLE DERIVATIVE; 4 (7 METHYL 3 ARYL 3,3A,4,5,6,7 HEXAHYDROINDAZOL 2 YL)BENZENESULFONAMIDE; 4 (7 METHYL 3 ARYL 4,5,6,7 TETRAHYDROINDAZOL 2 YL)BENZENESULFONAMIDE; 4 HYDRAZINOBENZENESULFONAMIDE; 6 ARYLIDENE 2 METHYLCYCLOHEXANONE DERIVATIVE; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTIMYCOBACTERIAL AGENT; ANTINEOPLASTIC AGENT; INDAZOLE DERIVATIVE; N1 [4 (7 METHYL 3 ARYL 3,3A,4,5,6,7 HEXAHYDROINDAZOL 2 YL)BENZENESULFONYL] N3 SUBSTITUTED UREA DERIVATIVE; N1 [4 (7 METHYL 3 ARYL 4,5,6,7 TETRAHYDROINDAZOLINE 2 YL)BENZENESULFONYL] N3 SUBSTITUTED UREA DERIVATIVE; SULFONAMIDE; UNCLASSIFIED DRUG; 4 (7 METHYL 3 ARYL 3,3A,4,5,6,7 HEXAHYDROINDAZOL 2 YL) BENZENESULFONAMIDE; 4 (7 METHYL 3 ARYL 4,5,6,7 TETRAHYDROINDAZOL 2 YL) BENZENESULFONAMIDE; THIOUREA DERIVATIVE; UREA DERIVATIVE;

AGAR DIFFUSION; ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASPERGILLUS NIGER; BACILLUS SUBTILIS; BREAST CANCER; CANDIDA ALBICANS; CARBON NUCLEAR MAGNETIC RESONANCE; CENTRAL NERVOUS SYSTEM TUMOR; COLON CANCER; DRUG SYNTHESIS; ESCHERICHIA COLI; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROMETRY; KIDNEY CANCER; LEUKEMIA; LUNG NON SMALL CELL CANCER; MELANOMA; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANT TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; OVARY CANCER; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROSTATE CANCER; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; TUMOR CELL LINE; A549 CELL LINE; ANTIMICROBIAL ACTIVITY; ELEMENTARY MICROANALYSIS; HCT116 CELL LINE; HL 60 CELL LINE; HT 29 CELL LINE; K562 CELL LINE; MCF 7 CELL LINE; MICROANALYSIS; NATIONAL HEALTH ORGANIZATION; UNITED STATES;

ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; ANTIFUNGAL AGENTS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHEMISTRY TECHNIQUES, SYNTHETIC; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; INDAZOLES; MAGNETIC RESONANCE SPECTROSCOPY; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS;

EID: 84875396327     PISSN: 14756366     EISSN: 14756374     Source Type: Journal    
DOI: 10.3109/14756366.2011.653354     Document Type: Article

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