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Volumn 18, Issue 2, 2013, Pages 197-202

Liver repopulation and regeneration: New approaches to old questions

Author keywords

Aneuploidy; Liver regeneration; Liver repopulation; Liver tissue engineering; Polyploidy

Indexed keywords

ANEUPLOIDY; HUMAN; LIVER CELL; LIVER INJURY; LIVER REGENERATION; NONHUMAN; POLYPLOIDY; REVIEW; TUMOR MICROENVIRONMENT;

EID: 84875394703     PISSN: 10872418     EISSN: 15317013     Source Type: Journal    
DOI: 10.1097/MOT.0b013e32835f07e2     Document Type: Review
Times cited : (26)

References (43)
  • 2
    • 73949091032 scopus 로고    scopus 로고
    • Liver regeneration after partial hepatectomy: Critical analysis of mechanistic dilemmas
    • Michalopoulos GK. Liver regeneration after partial hepatectomy: Critical analysis of mechanistic dilemmas. Am J Pathol 2010;176: 2-13
    • (2010) Am J Pathol , vol.176 , pp. 2-13
    • Michalopoulos, G.K.1
  • 4
    • 0038482108 scopus 로고    scopus 로고
    • Liver cell polyploidization: A pivotal role for binuclear hepatocytes
    • Guidotti JE, Bregerie O, Robert A, et al. Liver cell polyploidization: A pivotal role for binuclear hepatocytes. J Biol Chem 2003;278: 19095-19101
    • (2003) J Biol Chem , vol.278 , pp. 19095-19101
    • Guidotti, J.E.1    Bregerie, O.2    Robert, A.3
  • 5
    • 77958004840 scopus 로고    scopus 로고
    • The ploidy conveyor of mature hepatocytes as a source of genetic variation
    • Duncan AW, Taylor MH, Hickey RD, et al. The ploidy conveyor of mature hepatocytes as a source of genetic variation. Nature 2010;467: 707-710
    • (2010) Nature , vol.467 , pp. 707-710
    • Duncan, A.W.1    Taylor, M.H.2    Hickey, R.D.3
  • 7
    • 68449096617 scopus 로고    scopus 로고
    • The insulin/Akt pathway controls a specific cell division program that leads to generation of binucleated tetraploid liver cells in rodents
    • Celton-Morizur S, Merlen G, Couton D, et al. The insulin/Akt pathway controls a specific cell division program that leads to generation of binucleated tetraploid liver cells in rodents. J Clin Invest 2009;119: 1880-1887
    • (2009) J Clin Invest , vol.119 , pp. 1880-1887
    • Celton-Morizur, S.1    Merlen, G.2    Couton, D.3
  • 8
    • 36248956543 scopus 로고    scopus 로고
    • Liver tetraploidization is controlled by a new process of incomplete cytokinesis
    • Margall-Ducos G, Celton-Morizur S, Couton D, et al. Liver tetraploidization is controlled by a new process of incomplete cytokinesis. J Cell Sci 2007;120 (Pt 20):3633-3639
    • (2007) J Cell Sci , vol.120 , Issue.PART 20 , pp. 3633-3639
    • Margall-Ducos, G.1    Celton-Morizur, S.2    Couton, D.3
  • 9
    • 0013574814 scopus 로고
    • The histology of liver tissue regeneration
    • Milne LS. The histology of liver tissue regeneration. J Pathol Bacteriol 1909;13: 127-158
    • (1909) J Pathol Bacteriol , vol.13 , pp. 127-158
    • Milne, L.S.1
  • 10
    • 77957372850 scopus 로고    scopus 로고
    • Ageing, telomeres, senescence, and liver injury
    • Hoare M, Das T, Alexander G. Ageing, telomeres, senescence, and liver injury. J Hepatol 2010;53: 950-961
    • (2010) J Hepatol , vol.53 , pp. 950-961
    • Hoare, M.1    Das, T.2    Alexander, G.3
  • 11
    • 0032805945 scopus 로고    scopus 로고
    • The repopulation potential of hepatocyte populations differing in size and prior mitotic expansion
    • Overturf K, Al-Dhalimy M, Finegold M, Grompe M. The repopulation potential of hepatocyte populations differing in size and prior mitotic expansion. Am J Pathol 1999;155: 2135-2143
    • (1999) Am J Pathol , vol.155 , pp. 2135-2143
    • Overturf, K.1    Al-Dhalimy, M.2    Finegold, M.3    Grompe, M.4
  • 12
    • 0032974017 scopus 로고    scopus 로고
    • Partial hepatectomy-induced polyploidy attenuates hepatocyte replication and activates cell aging events
    • 5 Pt 1
    • Sigal SH, Rajvanshi P, Gorla GR, et al. Partial hepatectomy-induced polyploidy attenuates hepatocyte replication and activates cell aging events. Am J Physiol 1999;276 (5 Pt 1):G1260-G1272
    • (1999) Am J Physiol , vol.276
    • Sigal, S.H.1    Rajvanshi, P.2    Gorla, G.R.3
  • 13
    • 0033636738 scopus 로고    scopus 로고
    • Hepatocyte transplantation into diseased mouse liver. Kinetics of parenchymal repopulation and identification of the proliferative capacity of tetraploid and octaploid hepatocytes
    • Weglarz TC, Degen JL, Sandgren EP. Hepatocyte transplantation into diseased mouse liver. Kinetics of parenchymal repopulation and identification of the proliferative capacity of tetraploid and octaploid hepatocytes. Am J Pathol 2000;157: 1963-1974
    • (2000) Am J Pathol , vol.157 , pp. 1963-1974
    • Weglarz, T.C.1    Degen, J.L.2    Sandgren, E.P.3
  • 14
    • 80053988757 scopus 로고    scopus 로고
    • Single-cell analysis of ploidy and centrosomes underscores the peculiarity of normal hepatocytes
    • Faggioli F, Vezzoni P, Montagna C. Single-cell analysis of ploidy and centrosomes underscores the peculiarity of normal hepatocytes. PLoS One 2011;6:e26080
    • (2011) PLoS One , Issue.6
    • Faggioli, F.1    Vezzoni, P.2    Montagna, C.3
  • 15
    • 77951702768 scopus 로고    scopus 로고
    • Mechanisms of mosaicism, chimerism and uniparental disomy identified by single nucleotide polymorphism array analysis
    • Conlin LK, Thiel BD, Bonnemann CG, et al. Mechanisms of mosaicism, chimerism and uniparental disomy identified by single nucleotide polymorphism array analysis. Hum Mol Genet 2010;19: 1263-1275
    • (2010) Hum Mol Genet , vol.19 , pp. 1263-1275
    • Conlin, L.K.1    Thiel, B.D.2    Bonnemann, C.G.3
  • 16
    • 14544300125 scopus 로고    scopus 로고
    • Human cytotrophoblasts acquire aneuploidies as they differentiate to an invasive phenotype
    • Weier JF, Weier HU, Jung CJ, et al. Human cytotrophoblasts acquire aneuploidies as they differentiate to an invasive phenotype. Dev Biol 2005;279: 420-432
    • (2005) Dev Biol , vol.279 , pp. 420-432
    • Weier, J.F.1    Weier, H.U.2    Jung, C.J.3
  • 17
    • 41149121141 scopus 로고    scopus 로고
    • Aneuploid mosaicism in the developing and adult cerebellar cortex
    • Westra JW, Peterson SE, Yung YC, et al. Aneuploid mosaicism in the developing and adult cerebellar cortex. J Comp Neurol 2008;507: 1944-1951
    • (2008) J Comp Neurol , vol.507 , pp. 1944-1951
    • Westra, J.W.1    Peterson, S.E.2    Yung, Y.C.3
  • 18
    • 84862777815 scopus 로고    scopus 로고
    • Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy
    • Chen G, Bradford WD, Seidel CW, Li R. Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy. Nature 2012;482: 246- 250
    • (2012) Nature , vol.482 , pp. 246-250
    • Chen, G.1    Bradford, W.D.2    Seidel, C.W.3    Li, R.4
  • 19
    • 78149423336 scopus 로고    scopus 로고
    • Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast
    • Pavelka N, Rancati G, Zhu J, et al. Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast. Nature 2010;468: 321- 325
    • (2010) Nature , vol.468 , pp. 321-325
    • Pavelka, N.1    Rancati, G.2    Zhu, J.3
  • 20
    • 56349088536 scopus 로고    scopus 로고
    • Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motor
    • Rancati G, Pavelka N, Fleharty B, et al. Aneuploidy underlies rapid adaptive evolution of yeast cells deprived of a conserved cytokinesis motor. Cell 2008;135: 879-893
    • (2008) Cell , vol.135 , pp. 879-893
    • Rancati, G.1    Pavelka, N.2    Fleharty, B.3
  • 21
    • 84863691442 scopus 로고    scopus 로고
    • Karyotypic determinants of chromosome instability in aneuploid budding yeast
    • Zhu J, Pavelka N, Bradford WD, et al. Karyotypic determinants of chromosome instability in aneuploid budding yeast. PLoS Genet 2012;8:e1002719
    • (2012) PLoS Genet , Issue.8
    • Zhu, J.1    Pavelka, N.2    Bradford, W.D.3
  • 22
    • 84866000846 scopus 로고    scopus 로고
    • Aneuploidy as a mechanism for stress-induced liver adaptation
    • Duncan AW, Hanlon Newell AE, Bi W, et al. Aneuploidy as a mechanism for stress-induced liver adaptation. J Clin Invest 2012;122: 3307-3315
    • (2012) J Clin Invest , vol.122 , pp. 3307-3315
    • Duncan, A.W.1    Hanlon Newell, A.E.2    Bi, W.3
  • 24
    • 0033783568 scopus 로고    scopus 로고
    • Clonal analysis of micronodules in virus C-induced liver cirrhosis using laser capture microdissection (LCM) and HUMARA assay
    • Paradis V, Dargere D, Bonvoust F, et al. Clonal analysis of micronodules in virus C-induced liver cirrhosis using laser capture microdissection (LCM) and HUMARA assay. Lab Invest 2000;80: 1553-1559
    • (2000) Lab Invest , vol.80 , pp. 1553-1559
    • Paradis, V.1    Dargere, D.2    Bonvoust, F.3
  • 26
    • 84869751765 scopus 로고    scopus 로고
    • Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice
    • 1564e7-143: 1575e7
    • Espanol-Suner R, Carpentier R, Van Hul N, et al. Liver progenitor cells yield functional hepatocytes in response to chronic liver injury in mice. Gastroenterology 2012;143: 1564.e7-1575.e7
    • (2012) Gastroenterology , pp. 143
    • Espanol-Suner, R.1    Carpentier, R.2    Van Hul, N.3
  • 27
    • 84859614232 scopus 로고    scopus 로고
    • Macrophage-derived Wnt opposes notch signaling to specify hepatic progenitor cell fate in chronic liver disease
    • Boulter L, Govaere O, Bird TG, et al. Macrophage-derived Wnt opposes notch signaling to specify hepatic progenitor cell fate in chronic liver disease. Nat Med 2012;18: 572-579
    • (2012) Nat Med , vol.18 , pp. 572-579
    • Boulter, L.1    Govaere, O.2    Bird, T.G.3
  • 28
    • 84875404643 scopus 로고    scopus 로고
    • Promotion of liver regeneration by natural killer cells in mice is dependent on extracellular ATP phosphohydrolysis
    • Graubardt N, Fahrner R, Trochsler M, et al. Promotion of liver regeneration by natural killer cells in mice is dependent on extracellular ATP phosphohydrolysis. Hepatology 2012
    • Hepatology 2012
    • Graubardt, N.1    Fahrner, R.2    Trochsler, M.3
  • 29
    • 70249090374 scopus 로고    scopus 로고
    • Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance
    • Elliott MR, Chekeni FB, Trampont PC, et al. Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature 2009;461: 282-286
    • (2009) Nature , vol.461 , pp. 282-286
    • Elliott, M.R.1    Chekeni, F.B.2    Trampont, P.C.3
  • 30
    • 71149121137 scopus 로고    scopus 로고
    • ATP release after partial hepatectomy regulates liver regeneration in the rat
    • Gonzales E, Julien B, Serriere-Lanneau V, et al. ATP release after partial hepatectomy regulates liver regeneration in the rat. J Hepatol 2010;52: 54- 62
    • (2010) J Hepatol , vol.52 , pp. 54-62
    • Gonzales, E.1    Julien, B.2    Serriere-Lanneau, V.3
  • 31
    • 84859988520 scopus 로고    scopus 로고
    • The microenvironment in hepatocyte regeneration and function in rats with advanced cirrhosis
    • Liu L, Yannam GR, Nishikawa T, et al. The microenvironment in hepatocyte regeneration and function in rats with advanced cirrhosis. Hepatology 2012;55: 1529-1539
    • (2012) Hepatology , vol.55 , pp. 1529-1539
    • Liu, L.1    Yannam, G.R.2    Nishikawa, T.3
  • 32
    • 77952539714 scopus 로고    scopus 로고
    • Gap junction dysfunction reduces acetaminophen hepatotoxicity with impact on apoptotic signaling and connexin 43 protein induction in rat
    • Naiki-Ito A, Asamoto M, Naiki T, et al. Gap junction dysfunction reduces acetaminophen hepatotoxicity with impact on apoptotic signaling and connexin 43 protein induction in rat. Toxicol Pathol 2010;38: 280-286
    • (2010) Toxicol Pathol , vol.38 , pp. 280-286
    • Naiki-Ito, A.1    Asamoto, M.2    Naiki, T.3
  • 33
    • 84863012267 scopus 로고    scopus 로고
    • Gap junction inhibition prevents druginduced liver toxicity and fulminant hepatic failure
    • Patel SJ, Milwid JM, King KR, et al. Gap junction inhibition prevents druginduced liver toxicity and fulminant hepatic failure. Nat Biotechnol 2012;30: 179-183
    • (2012) Nat Biotechnol , vol.30 , pp. 179-183
    • Patel, S.J.1    Milwid, J.M.2    King, K.R.3
  • 34
    • 38949168818 scopus 로고    scopus 로고
    • Perfusion-decellularized matrix: Using nature's platform to engineer a bioartificial heart
    • Ott HC, Matthiesen TS, Goh SK, et al. Perfusion-decellularized matrix: Using nature's platform to engineer a bioartificial heart. Nat Med 2008;14: 213- 221
    • (2008) Nat Med , vol.14 , pp. 213-221
    • Ott, H.C.1    Matthiesen, T.S.2    Goh, S.K.3
  • 35
    • 84868611688 scopus 로고    scopus 로고
    • Perspectives on wholeorgan assembly: Moving toward transplantation on demand
    • Soto-Gutierrez A, Wertheim JA, Ott HC, Gilbert TW. Perspectives on wholeorgan assembly: Moving toward transplantation on demand. J Clin Invest 2012;122: 3817-3823
    • (2012) J Clin Invest , vol.122 , pp. 3817-3823
    • Soto-Gutierrez, A.1    Wertheim, J.A.2    Ott, H.C.3    Gilbert, T.W.4
  • 36
    • 79958288464 scopus 로고    scopus 로고
    • A whole-organ regenerative medicine approach for liver replacement
    • Soto-Gutierrez A, Zhang L, Medberry C, et al. A whole-organ regenerative medicine approach for liver replacement. Tissue Eng Part C Methods 2011;17: 677-686
    • (2011) Tissue Eng Part C Methods , Issue.17 , pp. 677-686
    • Soto-Gutierrez, A.1    Zhang, L.2    Medberry, C.3
  • 37
    • 77954533642 scopus 로고    scopus 로고
    • Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix
    • Uygun BE, Soto-Gutierrez A, Yagi H, et al. Organ reengineering through development of a transplantable recellularized liver graft using decellularized liver matrix. Nat Med 2010;16: 814-820
    • (2010) Nat Med , vol.16 , pp. 814-820
    • Uygun, B.E.1    Soto-Gutierrez, A.2    Yagi, H.3
  • 38
    • 79251521794 scopus 로고    scopus 로고
    • The use of whole organ decellularization for the generation of a vascularized liver organoid
    • Baptista PM, Siddiqui MM, Lozier G, et al. The use of whole organ decellularization for the generation of a vascularized liver organoid. Hepatology 2011;53: 604-617
    • (2011) Hepatology , vol.53 , pp. 604-617
    • Baptista, P.M.1    Siddiqui, M.M.2    Lozier, G.3
  • 39
    • 77955422758 scopus 로고    scopus 로고
    • Regeneration and orthotopic transplantation of a bioartificial lung
    • Ott HC, Clippinger B, Conrad C, et al. Regeneration and orthotopic transplantation of a bioartificial lung. Nat Med 2010;16: 927-933
    • (2010) Nat Med , Issue.16 , pp. 927-933
    • Ott, H.C.1    Clippinger, B.2    Conrad, C.3
  • 40
    • 77956092994 scopus 로고    scopus 로고
    • Influence of acellular natural lung matrix on murine embryonic stem cell differentiation and tissue formation
    • Cortiella J, Niles J, Cantu A, et al. Influence of acellular natural lung matrix on murine embryonic stem cell differentiation and tissue formation. Tissue Eng Part A 2010;16: 2565-2580
    • (2010) Tissue Eng Part A , Issue.16 , pp. 2565-2580
    • Cortiella, J.1    Niles, J.2    Cantu, A.3
  • 41
    • 2442457727 scopus 로고    scopus 로고
    • Mechanotransduction through growth-factor shedding into the extracellular space
    • Tschumperlin DJ, Dai G, Maly IV, et al. Mechanotransduction through growth-factor shedding into the extracellular space. Nature 2004;429: 83-86
    • (2004) Nature , vol.429 , pp. 83-86
    • Tschumperlin, D.J.1    Dai, G.2    Maly, I.V.3
  • 42
    • 78751608606 scopus 로고    scopus 로고
    • Lineage restriction of human hepatic stem cells to mature fates is made efficient by tissue-specific biomatrix scaffolds
    • Wang Y, Cui CB, Yamauchi M, et al. Lineage restriction of human hepatic stem cells to mature fates is made efficient by tissue-specific biomatrix scaffolds. Hepatology 2011;53: 293-305
    • (2011) Hepatology , vol.53 , pp. 293-305
    • Wang, Y.1    Cui, C.B.2    Yamauchi, M.3
  • 43
    • 77954608305 scopus 로고    scopus 로고
    • Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate
    • Huebsch N, Arany PR, Mao AS, et al. Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate. Nat Mater 2010;9: 518-526
    • (2010) Nat Mater , vol.9 , pp. 518-526
    • Huebsch, N.1    Arany, P.R.2    Mao, A.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.