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Volumn 19, Issue 11, 2013, Pages 1760-1769

Effects of small interfering RNA inhibit class I phosphoinositide 3-kinase on human gastric cancer cells

Author keywords

Apoptosis; Autophagy; Class I Phosphoinositide 3 kinase; Gastric cancer cells; Rna interference

Indexed keywords

BECLIN 1; MICROTUBULE ASSOCIATED PROTEIN 1; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN BCL 2; PROTEIN P53; SMALL INTERFERING RNA;

EID: 84875391503     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v19.i11.1760     Document Type: Article
Times cited : (6)

References (22)
  • 1
    • 33644681327 scopus 로고    scopus 로고
    • Epidemiology of gastric cancer
    • PMID:16489633
    • Crew KD, Neugut AI. Epidemiology of gastric cancer. World J Gastroenterol 2006; 12: 354-362 [PMID: 16489633]
    • (2006) World J Gastroenterol , vol.12 , pp. 354-362
    • Crew, K.D.1    Neugut, A.I.2
  • 2
    • 0037205048 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase pathway
    • PMID:12040186 DOI:10.1126/sci-ence.296.5573.1655
    • Cantley LC. The phosphoinositide 3-kinase pathway. Science 2002; 296: 1655-1657 [PMID: 12040186 DOI: 10.1126/sci-ence.296.5573.1655]
    • (2002) Science , vol.296 , pp. 1655-1657
    • Cantley, L.C.1
  • 3
    • 34447125097 scopus 로고    scopus 로고
    • AKT1 amplification regulates cisplatin resistance in human lung cancer cells through the mammalian target of rapamycin/ p70S6K1 pathway
    • PMID:17616691 DOI:10.1158/0008-5472.CAN-06-4261
    • Liu LZ, Zhou XD, Qian G, Shi X, Fang J, Jiang BH. AKT1 amplification regulates cisplatin resistance in human lung cancer cells through the mammalian target of rapamycin/ p70S6K1 pathway. Cancer Res 2007; 67: 6325-6332 [PMID: 17616691 DOI: 10.1158/0008-5472.CAN-06-4261]
    • (2007) Cancer Res , vol.67 , pp. 6325-6332
    • Liu, L.Z.1    Zhou, X.D.2    Qian, G.3    Shi, X.4    Fang, J.5    Jiang, B.H.6
  • 4
    • 44949112425 scopus 로고    scopus 로고
    • Expression of an activated mammalian target of rapamycin in adenocarcinoma of the cervix: A potential biomarker and molecular target therapy
    • PMID:18058806 DOI:10.1002/mc.20402
    • Faried LS, Faried A, Kanuma T, Aoki H, Sano T, Nakazato T, Tamura T, Kuwano H, Minegishi T. Expression of an activated mammalian target of rapamycin in adenocarcinoma of the cervix: A potential biomarker and molecular target therapy. Mol Carcinog 2008; 47: 446-457 [PMID: 18058806 DOI: 10.1002/mc.20402]
    • (2008) Mol Carcinog , vol.47 , pp. 446-457
    • Faried, L.S.1    Faried, A.2    Kanuma, T.3    Aoki, H.4    Sano, T.5    Nakazato, T.6    Tamura, T.7    Kuwano, H.8    Minegishi, T.9
  • 5
    • 33645516362 scopus 로고    scopus 로고
    • Akt-me-diated cisplatin resistance in ovarian cancer: Modulation of p53 action on caspase-dependent mitochondrial death pathway
    • PMID:16540663 DOI:10.1158/0008-5472.CAN-05-0425
    • Yang X, Fraser M, Moll UM, Basak A, Tsang BK. Akt-me-diated cisplatin resistance in ovarian cancer: modulation of p53 action on caspase-dependent mitochondrial death pathway. Cancer Res 2006; 66: 3126-3136 [PMID: 16540663 DOI: 10.1158/0008-5472.CAN-05-0425]
    • (2006) Cancer Res , vol.66 , pp. 3126-3136
    • Yang, X.1    Fraser, M.2    Moll, U.M.3    Basak, A.4    Tsang, B.K.5
  • 6
    • 33750742240 scopus 로고    scopus 로고
    • Predictive and prognostic role of activated mammalian target of rapamycin in cervical cancer treated with cisplatin-based neoadjuvant chemotherapy
    • PMID:16786123
    • Faried LS, Faried A, Kanuma T, Sano T, Nakazato T, Tamura T, Kuwano H, Minegishi T. Predictive and prognostic role of activated mammalian target of rapamycin in cervical cancer treated with cisplatin-based neoadjuvant chemotherapy. Oncol Rep 2006; 16: 57-63 [PMID: 16786123]
    • (2006) Oncol Rep , vol.16 , pp. 57-63
    • Faried, L.S.1    Faried, A.2    Kanuma, T.3    Sano, T.4    Nakazato, T.5    Tamura, T.6    Kuwano, H.7    Minegishi, T.8
  • 7
    • 34347331090 scopus 로고    scopus 로고
    • An activated mTOR/p70S6K signaling pathway in esophageal squamous cell carcinoma cell lines and inhibition of the pathway by rapamycin and siRNA against mTOR
    • PMID:17360108 DOI:10.1016/j.canlet.2007.01.026
    • Hou G, Xue L, Lu Z, Fan T, Tian F, Xue Y. An activated mTOR/p70S6K signaling pathway in esophageal squamous cell carcinoma cell lines and inhibition of the pathway by rapamycin and siRNA against mTOR. Cancer Lett 2007; 253: 236-248 [PMID: 17360108 DOI: 10.1016/j.canlet.2007.01.026]
    • (2007) Cancer Lett , vol.253 , pp. 236-248
    • Hou, G.1    Xue, L.2    Lu, Z.3    Fan, T.4    Tian, F.5    Xue, Y.6
  • 8
    • 15544369937 scopus 로고    scopus 로고
    • Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplifcation contributes to cisplatin resistance in an ovarian cancer cell line
    • PMID: 15790433 DOI: 10.1016/j.ygyno.2004.11.051
    • Lee S, Choi EJ, Jin C, Kim DH. Activation of PI3K/Akt pathway by PTEN reduction and PIK3CA mRNA amplifcation contributes to cisplatin resistance in an ovarian cancer cell line. Gynecol Oncol 2005; 97: 26-34 [PMID: 15790433 DOI: 10.1016/j.ygyno.2004.11.051]
    • (2005) Gynecol Oncol , vol.97 , pp. 26-34
    • Lee, S.1    Choi, E.J.2    Jin, C.3    Kim, D.H.4
  • 9
    • 32044466838 scopus 로고    scopus 로고
    • Exploiting the PI3K/AKT pathway for cancer drug discovery
    • PMID:16341064 DOI:10.1038/nrd1902
    • Hennessy BT, Smith DL, Ram PT, Lu Y, Mills GB. Exploiting the PI3K/AKT pathway for cancer drug discovery. Nat Rev Drug Discov 2005; 4: 988-1004 [PMID: 16341064 DOI: 10.1038/nrd1902]
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 988-1004
    • Hennessy, B.T.1    Smith, D.L.2    Ram, P.T.3    Lu, Y.4    Mills, G.B.5
  • 10
    • 0028836002 scopus 로고
    • Monodansylcadaverine (MDC) is a specifc in vivo marker for autophagic vacuoles
    • PMID:7750517
    • Biederbick A, Kern HF, Elsässer HP. Monodansylcadaverine (MDC) is a specifc in vivo marker for autophagic vacuoles. Eur J Cell Biol 1995; 66: 3-14 [PMID: 7750517]
    • (1995) Eur J Cell Biol , vol.66 , pp. 3-14
    • Biederbick, A.1    Kern, H.F.2    Elsässer, H.P.3
  • 11
    • 0035810045 scopus 로고    scopus 로고
    • Syner-gistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafuoride analogs in combination with either sodium butyrate or trichostatin A
    • PMID:11313934 DOI:10.1038/sj.onc.1204269
    • Rashid SF, Moore JS, Walker E, Driver PM, Engel J, Edwards CE, Brown G, Uskokovic MR, Campbell MJ. Syner-gistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafuoride analogs in combination with either sodium butyrate or trichostatin A. Oncogene 2001; 20: 1860-1872 [PMID: 11313934 DOI: 10.1038/ sj.onc.1204269]
    • (2001) Oncogene , vol.20 , pp. 1860-1872
    • Rashid, S.F.1    Moore, J.S.2    Walker, E.3    Driver, P.M.4    Engel, J.5    Edwards, C.E.6    Brown, G.7    Uskokovic, M.R.8    Campbell, M.J.9
  • 12
    • 0033997045 scopus 로고    scopus 로고
    • The lysosomotropic agent monodansylcadaverine also acts as a solvent polarity probe
    • PMID:10639491 DOI:10.1177/002215540004800210
    • Niemann A, Takatsuki A, Elsässer HP. The lysosomotropic agent monodansylcadaverine also acts as a solvent polarity probe. J Histochem Cytochem 2000; 48: 251-258 [PMID: 10639491 DOI: 10.1177/002215540004800210]
    • (2000) J Histochem Cytochem , vol.48 , pp. 251-258
    • Niemann, A.1    Takatsuki, A.2    Elsässer, H.P.3
  • 13
    • 0347626252 scopus 로고    scopus 로고
    • Autophagy: A regulated bulk degradation process inside cells
    • PMID:14684184
    • Yoshimori T. Autophagy: a regulated bulk degradation process inside cells. Biochem Biophys Res Commun 2004; 313: 453-458 [PMID: 14684184]
    • (2004) Biochem Biophys Res Commun , vol.313 , pp. 453-458
    • Yoshimori, T.1
  • 14
    • 0035970721 scopus 로고    scopus 로고
    • Nuclear and mitochondrial apoptotic pathways of p53
    • PMID:11286997 DOI: 10.1016/S0014-5793(01)02284-0
    • Moll UM, Zaika A. Nuclear and mitochondrial apoptotic pathways of p53. FEBS Lett 2001; 493: 65-69 [PMID: 11286997 DOI: 10.1016/S0014-5793(01)02284-0]
    • (2001) FEBS Lett , vol.493 , pp. 65-69
    • Moll, U.M.1    Zaika, A.2
  • 15
    • 3242690522 scopus 로고    scopus 로고
    • In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation
    • PMID:15254240 DOI:10.1128/MCB.24.15.6728-6741.2004
    • Erster S, Mihara M, Kim RH, Petrenko O, Moll UM. In vivo mitochondrial p53 translocation triggers a rapid first wave of cell death in response to DNA damage that can precede p53 target gene activation. Mol Cell Biol 2004; 24: 6728-6741 [PMID: 15254240 DOI: 10.1128/MCB.24.15.6728-6741.2004]
    • (2004) Mol Cell Biol , vol.24 , pp. 6728-6741
    • Erster, S.1    Mihara, M.2    Kim, R.H.3    Petrenko, O.4    Moll, U.M.5
  • 16
    • 9944240863 scopus 로고    scopus 로고
    • Splicing DNA-damage responses to tumour cell death
    • PMID:15585169 DOI:10.1142/S1363246904001614
    • Crighton D, Ryan KM. Splicing DNA-damage responses to tumour cell death. Biochim Biophys Acta 2004; 1705: 3-15 [PMID: 15585169 DOI: 10.1142/S1363246904001614]
    • (2004) Biochim Biophys Acta , vol.1705 , pp. 3-15
    • Crighton, D.1    Ryan, K.M.2
  • 17
    • 20344406240 scopus 로고    scopus 로고
    • Autophagy in metazoans: Cell survival in the land of plenty
    • PMID:15928708 DOI:10.1038/nrm1660
    • Lum JJ, DeBerardinis RJ, Thompson CB. Autophagy in metazoans: cell survival in the land of plenty. Nat Rev Mol Cell Biol 2005; 6: 439-448 [PMID: 15928708 DOI: 10.1038/ nrm1660]
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 439-448
    • Lum, J.J.1    Deberardinis, R.J.2    Thompson, C.B.3
  • 18
    • 0344142468 scopus 로고    scopus 로고
    • Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21
    • PMID:10395800 DOI:10.1006/geno.1999.5851
    • Aita VM, Liang XH, Murty VV, Pincus DL, Yu W, Cayanis E, Kalachikov S, Gilliam TC, Levine B. Cloning and genomic organization of beclin 1, a candidate tumor suppressor gene on chromosome 17q21. Genomics 1999; 59: 59-65 [PMID: 10395800 DOI: 10.1006/geno.1999.5851]
    • (1999) Genomics , vol.59 , pp. 59-65
    • Aita, V.M.1    Liang, X.H.2    Murty, V.V.3    Pincus, D.L.4    Yu, W.5    Cayanis, E.6    Kalachikov, S.7    Gilliam, T.C.8    Levine, B.9
  • 22
    • 34249037565 scopus 로고    scopus 로고
    • Crystal structure of the Bcl- XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein
    • PMID:17337444 DOI:10.1074/jbc.M700492200
    • Oberstein A, Jeffrey PD, Shi Y. Crystal structure of the Bcl- XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein. J Biol Chem 2007; 282: 13123-13132 [PMID: 17337444 DOI: 10.1074/jbc.M700492200]
    • (2007) J Biol Chem , vol.282 , pp. 13123-13132
    • Oberstein, A.1    Jeffrey, P.D.2    Shi, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.