메뉴 건너뛰기




Volumn 29, Issue 4, 2013, Pages 661-666

Quercetin reduces serum homocysteine level in rats fed a methionine-enriched diet

Author keywords

Antioxidant; Homocysteine; Quercetin; Rats

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBONYL DERIVATIVE; CYSTEINE; GLUTATHIONE; HOMOCYSTEINE; MALONALDEHYDE; METHIONINE; QUERCETIN; SERINE; SUPEROXIDE DISMUTASE; TAURINE;

EID: 84875372346     PISSN: 08999007     EISSN: 18731244     Source Type: Journal    
DOI: 10.1016/j.nut.2012.10.012     Document Type: Article
Times cited : (18)

References (43)
  • 2
    • 75149168269 scopus 로고    scopus 로고
    • The controversial role of B-vitamins in cardiovascular risk: an update
    • Ntaios G., Savopoulos C., Grekas D., Hatzitolios A. The controversial role of B-vitamins in cardiovascular risk: an update. Arch Cardiovasc Dis 2009, 102:847-854.
    • (2009) Arch Cardiovasc Dis , vol.102 , pp. 847-854
    • Ntaios, G.1    Savopoulos, C.2    Grekas, D.3    Hatzitolios, A.4
  • 3
    • 33646758588 scopus 로고    scopus 로고
    • The in vivo sparing of methionine by cysteine in sulfur amino acid requirements in animal models and adult humans
    • Ball R.O., Courtney-Martin G., Pencharz P.B. The in vivo sparing of methionine by cysteine in sulfur amino acid requirements in animal models and adult humans. J Nutr 2006, 136:1682S-1693S.
    • (2006) J Nutr , vol.136
    • Ball, R.O.1    Courtney-Martin, G.2    Pencharz, P.B.3
  • 4
    • 84862809910 scopus 로고    scopus 로고
    • Homocysteine induces cardiomyocyte dysfunction and apoptosis through p38 MAPK-mediated increase in oxidant stress
    • Wang X., Cui L., Joseph J., Jiang B., Pimental D., Handy D.E., et al. Homocysteine induces cardiomyocyte dysfunction and apoptosis through p38 MAPK-mediated increase in oxidant stress. J Mol Cell Cardiol 2012, 52:753-760.
    • (2012) J Mol Cell Cardiol , vol.52 , pp. 753-760
    • Wang, X.1    Cui, L.2    Joseph, J.3    Jiang, B.4    Pimental, D.5    Handy, D.E.6
  • 5
    • 77951667552 scopus 로고    scopus 로고
    • Plasma homocysteine and cardiovascular risk in heart failure with and without cardiorenal syndrome
    • Maurer M., Burri S., de Marchi S., Hullin R., Martinelli M., Mohacsi P., et al. Plasma homocysteine and cardiovascular risk in heart failure with and without cardiorenal syndrome. Int J Cardiol 2010, 141:32-38.
    • (2010) Int J Cardiol , vol.141 , pp. 32-38
    • Maurer, M.1    Burri, S.2    de Marchi, S.3    Hullin, R.4    Martinelli, M.5    Mohacsi, P.6
  • 6
    • 79951491488 scopus 로고    scopus 로고
    • Plasma homocysteine and the severity of heart failure in patients with previous myocardial infarction
    • Agoston-Coldea L., Mocan T., Gatfosse M., Lupu S., Dumitrascu D.L. Plasma homocysteine and the severity of heart failure in patients with previous myocardial infarction. Cardiol J 2011, 18:55-62.
    • (2011) Cardiol J , vol.18 , pp. 55-62
    • Agoston-Coldea, L.1    Mocan, T.2    Gatfosse, M.3    Lupu, S.4    Dumitrascu, D.L.5
  • 7
    • 33846138986 scopus 로고    scopus 로고
    • A comparison of arteries and veins in oxidative stress: products, destroyers, function, and disease
    • Szasz T., Thakali K., Fink G.D., Watts S.W. A comparison of arteries and veins in oxidative stress: products, destroyers, function, and disease. Exp Biol Med 2007, 232:27-37.
    • (2007) Exp Biol Med , vol.232 , pp. 27-37
    • Szasz, T.1    Thakali, K.2    Fink, G.D.3    Watts, S.W.4
  • 8
    • 0033806256 scopus 로고    scopus 로고
    • Physiological concentrations of homocysteine inhibits the human plasma GSH peroxidase that reduces organic hydroperoxides
    • Chen N., Liu Y., Greiner C.D., Holzman J.L. Physiological concentrations of homocysteine inhibits the human plasma GSH peroxidase that reduces organic hydroperoxides. J Lab Clin Med 2000, 136:58-65.
    • (2000) J Lab Clin Med , vol.136 , pp. 58-65
    • Chen, N.1    Liu, Y.2    Greiner, C.D.3    Holzman, J.L.4
  • 9
    • 78650387370 scopus 로고    scopus 로고
    • The homocysteine hypothesis: still relevant to the prevention and treatment of cardiovascular disease?
    • Abraham J.M., Cho L. The homocysteine hypothesis: still relevant to the prevention and treatment of cardiovascular disease?. Cleveland Clin J Med 2010, 77:911-918.
    • (2010) Cleveland Clin J Med , vol.77 , pp. 911-918
    • Abraham, J.M.1    Cho, L.2
  • 10
    • 33749258910 scopus 로고    scopus 로고
    • Low-dose folic acid supplementation reduces homocysteine concentration in hyperhomocysteinemic coronary artery disease patients
    • Lin P.T., Lee B.J., Chang H.H., Cheng C.H., Tsai A.J., Huang Y.C. Low-dose folic acid supplementation reduces homocysteine concentration in hyperhomocysteinemic coronary artery disease patients. Nutr Res 2006, 26:460-466.
    • (2006) Nutr Res , vol.26 , pp. 460-466
    • Lin, P.T.1    Lee, B.J.2    Chang, H.H.3    Cheng, C.H.4    Tsai, A.J.5    Huang, Y.C.6
  • 11
    • 43449106794 scopus 로고    scopus 로고
    • Trends in circulating concentrations of total homocysteine among US adolescents and adults: findings from the 1991-1994 and 1999-2004 national health and nutrition examination surveys
    • Pfeiffer C.M., Osterloh J.D., Kennedy-Stephenson J., Picciano M.F., Yetley E.A., Rader J.I., et al. Trends in circulating concentrations of total homocysteine among US adolescents and adults: findings from the 1991-1994 and 1999-2004 national health and nutrition examination surveys. Clin Chem 2008, 54:801-813.
    • (2008) Clin Chem , vol.54 , pp. 801-813
    • Pfeiffer, C.M.1    Osterloh, J.D.2    Kennedy-Stephenson, J.3    Picciano, M.F.4    Yetley, E.A.5    Rader, J.I.6
  • 13
    • 33745511245 scopus 로고    scopus 로고
    • The use of betaine in the treatment of elevated homocysteine
    • Lawson-Yuen A., Levy H.L. The use of betaine in the treatment of elevated homocysteine. Mol Genet Metab 2006, 88:201-207.
    • (2006) Mol Genet Metab , vol.88 , pp. 201-207
    • Lawson-Yuen, A.1    Levy, H.L.2
  • 14
    • 34547743420 scopus 로고    scopus 로고
    • Homocysteine-lowering therapy: a role in stroke prevention?
    • Spence J.D. Homocysteine-lowering therapy: a role in stroke prevention?. Lancet Neurol 2007, 6:830-838.
    • (2007) Lancet Neurol , vol.6 , pp. 830-838
    • Spence, J.D.1
  • 17
    • 84855179993 scopus 로고    scopus 로고
    • Protective effects of catechin and quercetin on antioxidant status, lipid peroxidation and testis-histoarchitecture induced by chlorpyrifos in male rats
    • Kalender Y., Kaya S., Durak D., Uzun F.G., Demir F. Protective effects of catechin and quercetin on antioxidant status, lipid peroxidation and testis-histoarchitecture induced by chlorpyrifos in male rats. Environ Toxicol Pharmacol 2012, 33:141-148.
    • (2012) Environ Toxicol Pharmacol , vol.33 , pp. 141-148
    • Kalender, Y.1    Kaya, S.2    Durak, D.3    Uzun, F.G.4    Demir, F.5
  • 18
    • 67650267213 scopus 로고    scopus 로고
    • Dietary flavonoids as antioxidants
    • Terao J. Dietary flavonoids as antioxidants. Forum Nutr 2009, 61:87-94.
    • (2009) Forum Nutr , vol.61 , pp. 87-94
    • Terao, J.1
  • 19
    • 0037471608 scopus 로고    scopus 로고
    • Simultaneous determination of all polyphenols in vegetables, fruits, and teas
    • Sakakibara H., Honda Y., Nakagawa S., Ashida H., Kanazawa K. Simultaneous determination of all polyphenols in vegetables, fruits, and teas. J Agric Food Chem 2003, 51:571-581.
    • (2003) J Agric Food Chem , vol.51 , pp. 571-581
    • Sakakibara, H.1    Honda, Y.2    Nakagawa, S.3    Ashida, H.4    Kanazawa, K.5
  • 20
    • 0041589462 scopus 로고    scopus 로고
    • Antidiabetic effects of quercetin in streptozocin-induced diabetic rats
    • Vessal M., Hemmati M., Vasei M. Antidiabetic effects of quercetin in streptozocin-induced diabetic rats. Comp Biochem Physiol Part C 2003, 135:357-364.
    • (2003) Comp Biochem Physiol Part C , vol.135 , pp. 357-364
    • Vessal, M.1    Hemmati, M.2    Vasei, M.3
  • 21
    • 85047684223 scopus 로고    scopus 로고
    • Cardioprotective actions of two bioflavonoids, quercetin and rutin in experimental myocardial infarction in both normal and streptozotocin-induced type 1 diabetic rats
    • Annapurna A., Reddy C.S., Akondi R.B., Rao S.R. Cardioprotective actions of two bioflavonoids, quercetin and rutin in experimental myocardial infarction in both normal and streptozotocin-induced type 1 diabetic rats. J Pharm Pharmacol 2009, 61:1365-1374.
    • (2009) J Pharm Pharmacol , vol.61 , pp. 1365-1374
    • Annapurna, A.1    Reddy, C.S.2    Akondi, R.B.3    Rao, S.R.4
  • 22
    • 79958858748 scopus 로고    scopus 로고
    • Dietary quercetin supplementation increase serum antioxidant capacity and alters hepatic gene expression profile in rats
    • Zhao L.T., Wu J.Q., Yang J.J., Wei J.Y., Gao W.N., Guo C.J. Dietary quercetin supplementation increase serum antioxidant capacity and alters hepatic gene expression profile in rats. Exp Biol Med 2011, 236:701-706.
    • (2011) Exp Biol Med , vol.236 , pp. 701-706
    • Zhao, L.T.1    Wu, J.Q.2    Yang, J.J.3    Wei, J.Y.4    Gao, W.N.5    Guo, C.J.6
  • 23
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76 rodent diet
    • Reeves P.G., Nielsen F.H., Fahey G.C. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76 rodent diet. J Nutr 1993, 123:1939-1951.
    • (1993) J Nutr , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey, G.C.3
  • 24
    • 43249103554 scopus 로고    scopus 로고
    • Dietary methionine effects on plasma homocysteine and HDL metabolism in mice
    • Velez-Carrasco W., Merkel M., Twiss C.O., Smith J.D. Dietary methionine effects on plasma homocysteine and HDL metabolism in mice. J Nutr Biochem 2008, 19:362-370.
    • (2008) J Nutr Biochem , vol.19 , pp. 362-370
    • Velez-Carrasco, W.1    Merkel, M.2    Twiss, C.O.3    Smith, J.D.4
  • 25
  • 26
    • 20444405056 scopus 로고    scopus 로고
    • Flavonoids from almond skins are bioavailable and act synergistically with vitamins C and E to enhance hamster and human LDL resistance to oxidation
    • Chen C.Y., Milbury P.E., Lapsley K., Blumberg J.B. Flavonoids from almond skins are bioavailable and act synergistically with vitamins C and E to enhance hamster and human LDL resistance to oxidation. J Nutr 2005, 135:1366-1373.
    • (2005) J Nutr , vol.135 , pp. 1366-1373
    • Chen, C.Y.1    Milbury, P.E.2    Lapsley, K.3    Blumberg, J.B.4
  • 27
    • 0034833507 scopus 로고    scopus 로고
    • Measurement of homocysteine and other aminothiols in plasma: advantages of using tris (2-carboxyethyl) phosphine as reductant compared with tri-n-butylphosphine
    • Krijt J., Vaková M., Kožich V. Measurement of homocysteine and other aminothiols in plasma: advantages of using tris (2-carboxyethyl) phosphine as reductant compared with tri-n-butylphosphine. Clin Chem 2001, 47:1821-1828.
    • (2001) Clin Chem , vol.47 , pp. 1821-1828
    • Krijt, J.1    Vaková, M.2    Kožich, V.3
  • 28
    • 0030586361 scopus 로고    scopus 로고
    • The ferric reducing ability of plasma as a measure of antioxidant power: FRAP assay
    • Benzie I.F.F., Strain J.J. The ferric reducing ability of plasma as a measure of antioxidant power: FRAP assay. Anal Biochem 1996, 239:70-76.
    • (1996) Anal Biochem , vol.239 , pp. 70-76
    • Benzie, I.F.F.1    Strain, J.J.2
  • 29
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H., Ohishi N., Kunio Y. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979, 95:351-358.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Kunio, Y.3
  • 30
    • 0031593043 scopus 로고    scopus 로고
    • Does oxidative protein damage play a role in the pathogenesis of carbon tetrachloride-induced liver injury in the rat?
    • Sundari P.N., Wilfred G., Ramakrishna B. Does oxidative protein damage play a role in the pathogenesis of carbon tetrachloride-induced liver injury in the rat?. Biochim Biophys Acta 1997, 1362:169-176.
    • (1997) Biochim Biophys Acta , vol.1362 , pp. 169-176
    • Sundari, P.N.1    Wilfred, G.2    Ramakrishna, B.3
  • 33
    • 0035692180 scopus 로고    scopus 로고
    • Human metabolism of dietary flavonoids: identification of plasma metabolites of quercetin
    • Day A.J., Mellon F., Barron D., Sarrazin G., Morgan M.R.A., Williamson G. Human metabolism of dietary flavonoids: identification of plasma metabolites of quercetin. Free Radic Res 2001, 35:941-952.
    • (2001) Free Radic Res , vol.35 , pp. 941-952
    • Day, A.J.1    Mellon, F.2    Barron, D.3    Sarrazin, G.4    Morgan, M.R.A.5    Williamson, G.6
  • 34
    • 51049095905 scopus 로고    scopus 로고
    • Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans
    • Egert S., Wolffram S., Bosy-Westphal A., Boesch-Saadatmandi C., Wagner A.E., et al. Daily quercetin supplementation dose-dependently increases plasma quercetin concentrations in healthy humans. J Nutr 2008, 138:1615-1621.
    • (2008) J Nutr , vol.138 , pp. 1615-1621
    • Egert, S.1    Wolffram, S.2    Bosy-Westphal, A.3    Boesch-Saadatmandi, C.4    Wagner, A.E.5
  • 35
    • 0037070378 scopus 로고    scopus 로고
    • Combination of lipids and emulsifier enhances the absorption of orally administered quercetin in rats
    • Azuma K., Ippoushi K., Ito H., Higashio H., Terao J. Combination of lipids and emulsifier enhances the absorption of orally administered quercetin in rats. J Agric Food Chem 2002, 50:1706-1712.
    • (2002) J Agric Food Chem , vol.50 , pp. 1706-1712
    • Azuma, K.1    Ippoushi, K.2    Ito, H.3    Higashio, H.4    Terao, J.5
  • 36
    • 77549086969 scopus 로고    scopus 로고
    • Evaluation of tolerable levels of dietary quercetin for exerting its antioxidative effect in high cholesterol-fed rats
    • Azuma K., Ippoushi K., Terao J. Evaluation of tolerable levels of dietary quercetin for exerting its antioxidative effect in high cholesterol-fed rats. Food Chem Toxicol 2010, 48:1117-1122.
    • (2010) Food Chem Toxicol , vol.48 , pp. 1117-1122
    • Azuma, K.1    Ippoushi, K.2    Terao, J.3
  • 37
    • 0042845711 scopus 로고    scopus 로고
    • Protection against hepatic ischemia-reperfusion injury in rats by oral pretreatment with quercetin
    • Su J.F., Guo C.J., Wei J.Y., Yang J.J., Jiang Y.G., Li Y.F. Protection against hepatic ischemia-reperfusion injury in rats by oral pretreatment with quercetin. Biomed Environ Sci 2003, 16:1-8.
    • (2003) Biomed Environ Sci , vol.16 , pp. 1-8
    • Su, J.F.1    Guo, C.J.2    Wei, J.Y.3    Yang, J.J.4    Jiang, Y.G.5    Li, Y.F.6
  • 38
    • 1542436560 scopus 로고    scopus 로고
    • Quercetin, a flavonoid antioxidant, prevents and protects against ethanol-induced oxidative stress in mouse liver
    • Molina M.F., Sanchez-Reus I., Iglesias I., Benedi J. Quercetin, a flavonoid antioxidant, prevents and protects against ethanol-induced oxidative stress in mouse liver. Biol Pharm Bull 2003, 26:1398-1402.
    • (2003) Biol Pharm Bull , vol.26 , pp. 1398-1402
    • Molina, M.F.1    Sanchez-Reus, I.2    Iglesias, I.3    Benedi, J.4
  • 39
    • 26444581298 scopus 로고    scopus 로고
    • Quercetin decreases oxidative stress, NF-kappaB activation, and iNOS overexpression in liver of streptozotocin-induced diabetic rats
    • Dias A.S., Porawski M., Alonso M., Marroni N., Collado P.S., González-Gallego J. Quercetin decreases oxidative stress, NF-kappaB activation, and iNOS overexpression in liver of streptozotocin-induced diabetic rats. J Nutr 2005, 135:2299-2304.
    • (2005) J Nutr , vol.135 , pp. 2299-2304
    • Dias, A.S.1    Porawski, M.2    Alonso, M.3    Marroni, N.4    Collado, P.S.5    González-Gallego, J.6
  • 40
    • 35848966138 scopus 로고    scopus 로고
    • Antioxidant capacity of albumin-bound quercetin metabolites after onion consumption in humans
    • Murota K., Hotta A., Ido H., Kawai Y., Moon J.H., Sekido K., et al. Antioxidant capacity of albumin-bound quercetin metabolites after onion consumption in humans. J Med Invest 2007, 54:370-374.
    • (2007) J Med Invest , vol.54 , pp. 370-374
    • Murota, K.1    Hotta, A.2    Ido, H.3    Kawai, Y.4    Moon, J.H.5    Sekido, K.6
  • 41
    • 0031020195 scopus 로고    scopus 로고
    • Antioxidant and prooxidant behavior of flavonoids: structure-activity relationships
    • Cao G., Sofic E., Prior R.L. Antioxidant and prooxidant behavior of flavonoids: structure-activity relationships. Free Radic Biol Med 1997, 22:749-760.
    • (1997) Free Radic Biol Med , vol.22 , pp. 749-760
    • Cao, G.1    Sofic, E.2    Prior, R.L.3
  • 42
    • 0043166966 scopus 로고    scopus 로고
    • Oxidized quercetin reacts with thiols rather than with ascorbate: implication for quercetin supplementation
    • Boots A.W., Kubben N., Haenen G.R., Bast A. Oxidized quercetin reacts with thiols rather than with ascorbate: implication for quercetin supplementation. Biochem Biophys Res Commun 2003, 308:560-565.
    • (2003) Biochem Biophys Res Commun , vol.308 , pp. 560-565
    • Boots, A.W.1    Kubben, N.2    Haenen, G.R.3    Bast, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.