메뉴 건너뛰기




Volumn 432, Issue 1, 2013, Pages 5-9

3-Methyladenine induces cell death and its interaction with chemotherapeutic drugs is independent of autophagy

Author keywords

3 Methyladenine; Autophagy; Cancer cells; Chemotherapy

Indexed keywords

3 METHYLADENINE; ANTINEOPLASTIC AGENT; FLUOROURACIL; PLATINUM DERIVATIVE; TAMOXIFEN; TETRAZOLIUM;

EID: 84875364684     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.01.106     Document Type: Article
Times cited : (41)

References (23)
  • 2
    • 77953699668 scopus 로고    scopus 로고
    • Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer
    • Dalby K.N., Tekedereli I., Lopez-Berestein G., Ozpolat B. Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer. Autophagy 2010, 6:322-329.
    • (2010) Autophagy , vol.6 , pp. 322-329
    • Dalby, K.N.1    Tekedereli, I.2    Lopez-Berestein, G.3    Ozpolat, B.4
  • 5
    • 43949131433 scopus 로고    scopus 로고
    • Autophagic cell death unraveled: pharmacological inhibition of apoptosis and autophagy enables necrosis
    • White E. Autophagic cell death unraveled: pharmacological inhibition of apoptosis and autophagy enables necrosis. Autophagy 2008, 4:399-401.
    • (2008) Autophagy , vol.4 , pp. 399-401
    • White, E.1
  • 6
    • 84857873299 scopus 로고    scopus 로고
    • Autophagy and cancer
    • Choi K.S. Autophagy and cancer. Exp. Mol. Med. 2012, 44:109-120.
    • (2012) Exp. Mol. Med. , vol.44 , pp. 109-120
    • Choi, K.S.1
  • 7
    • 77957367974 scopus 로고    scopus 로고
    • Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies
    • Yang P.M., Liu Y.L., Lin Y.C., Shun C.T., Wu M.S., Chen C.C. Inhibition of autophagy enhances anticancer effects of atorvastatin in digestive malignancies. Cancer Res. 2010, 70:7699-7709.
    • (2010) Cancer Res. , vol.70 , pp. 7699-7709
    • Yang, P.M.1    Liu, Y.L.2    Lin, Y.C.3    Shun, C.T.4    Wu, M.S.5    Chen, C.C.6
  • 9
    • 0005677775 scopus 로고
    • 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes
    • Seglen P.O., Gordon P.B. 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc. Natl. Acad. Sci. USA 1982, 79:1889-1892.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 1889-1892
    • Seglen, P.O.1    Gordon, P.B.2
  • 10
    • 33847008972 scopus 로고    scopus 로고
    • DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells
    • Katayama M., Kawaguchi T., Berger M.S., Pieper R.O. DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells. Cell Death Differ. 2007, 14:548-558.
    • (2007) Cell Death Differ. , vol.14 , pp. 548-558
    • Katayama, M.1    Kawaguchi, T.2    Berger, M.S.3    Pieper, R.O.4
  • 11
    • 60449092595 scopus 로고    scopus 로고
    • Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells
    • Li J., Hou N., Faried A., Tsutsumi S., Takeuchi T., Kuwano H. Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells. Ann. Surg. Oncol. 2009, 16:761-771.
    • (2009) Ann. Surg. Oncol. , vol.16 , pp. 761-771
    • Li, J.1    Hou, N.2    Faried, A.3    Tsutsumi, S.4    Takeuchi, T.5    Kuwano, H.6
  • 12
    • 70349316711 scopus 로고    scopus 로고
    • The prosurvival role of autophagy in Resveratrol-induced cytotoxicity in human U251 glioma cells
    • Li J., Qin Z., Liang Z. The prosurvival role of autophagy in Resveratrol-induced cytotoxicity in human U251 glioma cells. BMC Cancer 2009, 9:215.
    • (2009) BMC Cancer , vol.9 , pp. 215
    • Li, J.1    Qin, Z.2    Liang, Z.3
  • 13
    • 77951217000 scopus 로고    scopus 로고
    • Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase
    • Wu Y.T., Tan H.L., Shui G., Bauvy C., Huang Q., Wenk M.R., Ong C.N., Codogno P., Shen H.M. Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. J. Biol. Chem. 2010, 285:10850-10861.
    • (2010) J. Biol. Chem. , vol.285 , pp. 10850-10861
    • Wu, Y.T.1    Tan, H.L.2    Shui, G.3    Bauvy, C.4    Huang, Q.5    Wenk, M.R.6    Ong, C.N.7    Codogno, P.8    Shen, H.M.9
  • 14
    • 84872845688 scopus 로고    scopus 로고
    • The autophagic inhibitor 3-methyladenine (3-MA) potently stimulates PKA-dependent lipolysis in adipocytes
    • Heckmann B.L., Yang X., Zhang X., Liu J. The autophagic inhibitor 3-methyladenine (3-MA) potently stimulates PKA-dependent lipolysis in adipocytes. Br. J. Pharmacol. 2012, 10.1111/j.1476-5381.2012.02110.x.
    • (2012) Br. J. Pharmacol.
    • Heckmann, B.L.1    Yang, X.2    Zhang, X.3    Liu, J.4
  • 15
    • 84862911535 scopus 로고    scopus 로고
    • Large T-antigen up-regulates Kv4.3 K(+) channels through Sp1, and Kv4.3 K+ channels contribute to cell apoptosis and necrosis through activation of calcium/calmodulin-dependent protein kinase II
    • Li Q., Zhang Y., Sheng Y., Huo R., Sun B., Teng X., Li N., Zhu J.X., Yang B.F., Dong D.L. Large T-antigen up-regulates Kv4.3 K(+) channels through Sp1, and Kv4.3 K+ channels contribute to cell apoptosis and necrosis through activation of calcium/calmodulin-dependent protein kinase II. Biochem. J. 2012, 441:859-867.
    • (2012) Biochem. J. , vol.441 , pp. 859-867
    • Li, Q.1    Zhang, Y.2    Sheng, Y.3    Huo, R.4    Sun, B.5    Teng, X.6    Li, N.7    Zhu, J.X.8    Yang, B.F.9    Dong, D.L.10
  • 16
    • 0028153260 scopus 로고
    • Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: a rational approach to clinical protocol design
    • Chou T.C., Motzer R.J., Tong Y., Bosl G.J. Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: a rational approach to clinical protocol design. J. Natl. Cancer Inst. 1994, 86:1517-1524.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 1517-1524
    • Chou, T.C.1    Motzer, R.J.2    Tong, Y.3    Bosl, G.J.4
  • 17
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors
    • Chou T.C., Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv. Enzyme Regul. 1984, 22:27-55.
    • (1984) Adv. Enzyme Regul. , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 19
    • 84860159791 scopus 로고    scopus 로고
    • Inhibitors of phosphatidylinositol 3'-kinases promote mitotic cell death in Hela cells
    • Hou H., Zhang Y., Huang Y., Yi Q., Lv L., Zhang T., Chen D., Hao Q., Shi Q. Inhibitors of phosphatidylinositol 3'-kinases promote mitotic cell death in Hela cells. PLoS One 2012, 7:e35665.
    • (2012) PLoS One , vol.7
    • Hou, H.1    Zhang, Y.2    Huang, Y.3    Yi, Q.4    Lv, L.5    Zhang, T.6    Chen, D.7    Hao, Q.8    Shi, Q.9
  • 20
    • 67549084381 scopus 로고    scopus 로고
    • Superoxide is the major reactive oxygen species regulating autophagy
    • Chen Y., Azad M.B., Gibson S.B. Superoxide is the major reactive oxygen species regulating autophagy. Cell Death Differ. 2009, 16:1040-1052.
    • (2009) Cell Death Differ. , vol.16 , pp. 1040-1052
    • Chen, Y.1    Azad, M.B.2    Gibson, S.B.3
  • 22
    • 79957628179 scopus 로고    scopus 로고
    • Autophagy inhibition promotes paclitaxel-induced apoptosis in cancer cells
    • Xi G., Hu X., Wu B., Jiang H., Young C.Y., Pang Y., Yuan H. Autophagy inhibition promotes paclitaxel-induced apoptosis in cancer cells. Cancer Lett. 2011, 307:141-148.
    • (2011) Cancer Lett. , vol.307 , pp. 141-148
    • Xi, G.1    Hu, X.2    Wu, B.3    Jiang, H.4    Young, C.Y.5    Pang, Y.6    Yuan, H.7
  • 23
    • 35148868751 scopus 로고    scopus 로고
    • 3-Methyladenine suppresses cell migration and invasion of HT1080 fibrosarcoma cells through inhibiting phosphoinositide 3-kinases independently of autophagy inhibition
    • Ito S., Koshikawa N., Mochizuki S., Takenaga K. 3-Methyladenine suppresses cell migration and invasion of HT1080 fibrosarcoma cells through inhibiting phosphoinositide 3-kinases independently of autophagy inhibition. Int. J. Oncol. 2007, 31:261-268.
    • (2007) Int. J. Oncol. , vol.31 , pp. 261-268
    • Ito, S.1    Koshikawa, N.2    Mochizuki, S.3    Takenaga, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.