Large T-antigen up-regulates K v4.3 K + channels through Sp1, and K v4.3 K + channels contribute to cell apoptosis and necrosis through activation of calcium/calmodulin-dependent protein kinase II

Biochemical Journal

Volumn 441, Issue 3, 2012, Pages 859-867

  Li, Qi ^a   Zhang, Ying ^a   Sheng, Yue ^a   Huo, Rong ^a   Sun, Bo ^a   Teng, Xue ^a   Li, Na ^a   Zhu, Jiu Xin ^a   Yang, Bao Feng ^a   Dong, De Li ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; Calcium calmodulin dependent protein kinase II (CaMKII); Human embryonic kidney (HEK) cell; K v4.3 potassium channel; Large T antigen; Necrosis

Indexed keywords

4 AMINOPYRIDINE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; PLASMID VECTOR; POTASSIUM CHANNEL; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SP1; VIRUS LARGE T ANTIGEN;

APOPTOSIS; ARTICLE; CELL DEATH; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANTIGENS, VIRAL, TUMOR; APOPTOSIS; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELL PROLIFERATION; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; MODELS, BIOLOGICAL; NECROSIS; RNA, SMALL INTERFERING; SHAL POTASSIUM CHANNELS; SP1 TRANSCRIPTION FACTOR; UP-REGULATION;

EID: 84862911535     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111604     Document Type: Article

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