Hydroxylated polybrominated diphenyl ethers exhibit different activities on thyroid hormone receptors depending on their degree of bromination

Toxicology and Applied Pharmacology

Volumn 268, Issue 3, 2013, Pages 256-263

  Ren, Xiao Min ^a   Guo, Liang Hong ^a   Gao, Yu ^a   Zhang, Bin Tian ^a   Wan, Bin ^a  

^a RESEARCH CENTER FOR ECO ENVIRONMENTAL SCIENCES   (China)

Author keywords

Coactivator binding assay; EC50; IC50; Kow; Ligand binding assay; OH PBDEs; P value; PBDEs; T screen assay; Thyroid hormone receptor

Indexed keywords

POLYBROMINATED DIPHENYL ETHER; THYROID HORMONE RECEPTOR;

ARTICLE; BINDING ASSAY; BINDING SITE; BROMINATION; CELL ASSAY; CELL PROLIFERATION; CELL STRAIN GH3; CONTROLLED STUDY; HORMONE ACTION; HORMONE RECEPTOR INTERACTION; HUMAN; HYDROXYLATION; MOLECULAR DOCKING; RECEPTOR AFFINITY;

ANIMALS; CELL LINE, TUMOR; HALOGENATED DIPHENYL ETHERS; HALOGENATION; HUMANS; HYDROXYLATION; PROTEIN BINDING; RATS; RECEPTORS, THYROID HORMONE;

EID: 84875293785     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.01.026     Document Type: Article

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