Soluplus®: A novel polymeric solubilizer for optimization of Carvedilol solid dispersions: Formulation design and effect of method of preparation

Powder Technology

Volumn 237, Issue , 2013, Pages 406-414

  Shamma, Rehab N ^a   Basha, Mona ^b  

^a CAIRO UNIVERSITY   (Egypt)

^b NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Carvedilol; Solid dispersion; Soluplus

Indexed keywords

CARVEDILOL; CRYSTALLINE-TO-AMORPHOUS; FOURIER TRANSFORMATIONS; POORLY WATER-SOLUBLE DRUGS; SOLID DISPERSION; SOLID STATE CHARACTERIZATION; THREE DIFFERENT TECHNIQUES; X-RAY DIFFRACTION STUDIES;

BIOCHEMISTRY; DIFFERENTIAL SCANNING CALORIMETRY; FOURIER TRANSFORMS; GRAFT COPOLYMERS; INFRARED SPECTROSCOPY; POLYVINYL ACETATES; SCANNING ELECTRON MICROSCOPY; SOLUBILITY; SPRAY DRYING; X RAY DIFFRACTION;

DISPERSIONS;

CARVEDILOL; COPOLYMER; FILLER; MANNITOL; POLYVINYL CAPROLACTAM POLYVINYL ACETATE POLYETHYLENE GLYCOL GRAFT COPOLYMER; UNCLASSIFIED DRUG;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG SOLUBILITY; FREEZE DRYING; INFRARED SPECTROSCOPY; ORODISPERSABLE TABLET FORMULATION; SCANNING ELECTRON MICROSCOPY; SOLID DISPERSION; SOLVENT EVAPORATION; SPRAY DRYING; TABLET DISINTEGRATION TIME; TABLET FORMULATION; TABLET HARDNESS; X RAY DIFFRACTION;

EID: 84875274738     PISSN: 00325910     EISSN: 1873328X     Source Type: Journal    
DOI: 10.1016/j.powtec.2012.12.038     Document Type: Article

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