In sight into tadalafil - block copolymer binary solid dispersion: Mechanistic investigation of dissolution enhancement

International Journal of Pharmaceutics

Volumn 402, Issue 1-2, 2010, Pages 78-88

  Mehanna, Mohammed M ^a   Motawaa, Adel M ^a   Samaha, Magda W ^a  

^a Alexandria University Faculty of Pharmacy   (Egypt)

Author keywords

Block copolymer; Enhancement mechanisms; Pluronics ; Solid dispersion; Tadalafil

Indexed keywords

COPOLYMER; DRUG CARRIER; PLURONICS; POLOXAMER; TADALAFIL; UNCLASSIFIED DRUG;

ARTICLE; CONTACT ANGLE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG PENETRATION; DRUG SOLUBILITY; FEASIBILITY STUDY; IN VITRO STUDY; INFRARED SPECTROSCOPY; MATHEMATICAL MODEL; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SOLID STATE; SOLUBILIZATION; TECHNIQUE; TECHNOLOGY; THERMODYNAMICS; X RAY POWDER DIFFRACTION;

CARBOLINES; CRYSTALLIZATION; DRUG CARRIERS; MODELS, CHEMICAL; MODELS, THEORETICAL; PHOSPHODIESTERASE 5 INHIBITORS; POLOXAMER; SOLUBILITY; TECHNOLOGY, PHARMACEUTICAL; THERMODYNAMICS;

EID: 78349312679     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.09.024     Document Type: Article

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