Thermal processing of a poorly water-soluble drug substance exhibiting a high melting point: The utility of KinetiSol ® Dispersing

International Journal of Pharmaceutics

Volumn 419, Issue 1-2, 2011, Pages 222-230

  Hughey, Justin R ^a   Keen, Justin M ^a   Brough, Chris ^b   Saeger, Sophie ^c   McGinity, James W ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b DisperSol Technologies LLC   (United States)

^c FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

High melting point drug substance; Hot melt extrusion; KinetiSol Dispersing; Meloxicam; Solid dispersion; Thermally labile

Indexed keywords

MELOXICAM; POLYMER;

ARTICLE; DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DRUG SOLUBILITY; DRUG STABILITY; HYDROPHILICITY; MELTING POINT; MISCIBILITY; PRIORITY JOURNAL; SOLID; THERMOGRAVIMETRY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DRUG CARRIERS; DRUG STABILITY; FEASIBILITY STUDIES; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; POLYMERS; SOLUBILITY; TABLETS; TEMPERATURE; THIAZINES; THIAZOLES; TIME FACTORS; TRANSITION TEMPERATURE; WATER;

EID: 80053570332     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.08.007     Document Type: Article

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