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Volumn 49, Issue 4, 2013, Pages 287-292

Epithelial to mesenchymal transition in head and neck squamous cell carcinoma

Author keywords

E Cadherin; Epithelial to mesenchymal transition; Head and neck cancer; Invasion; Motility; Vimentin

Indexed keywords

CELL ADHESION MOLECULE; GROWTH FACTOR; GROWTH FACTOR RECEPTOR;

EID: 84875274632     PISSN: 13688375     EISSN: 18790593     Source Type: Journal    
DOI: 10.1016/j.oraloncology.2012.10.009     Document Type: Review
Times cited : (203)

References (77)
  • 1
    • 0003964363 scopus 로고    scopus 로고
    • American Cancer Society Atlanta: American Cancer Society
    • American Cancer Society. Cancer Facts & Figures 2011. Atlanta: American Cancer Society; 2011.
    • (2011) Cancer Facts & Figures 2011
  • 3
    • 84857246429 scopus 로고    scopus 로고
    • Head and neck tumors
    • Pazdur R, Wagman L, Camphausen K, Hoskins W, editors 13th ed. Manhassett: CMP Health, Media
    • Glisson B, Cango M, Feigenberg S. Head and neck tumors. In: Pazdur R, Wagman L, Camphausen K, Hoskins W, editors. Cancer management: a multidisciplinary approach. 13th ed. Manhassett: CMP Health, Media; 2011.
    • (2011) Cancer Management: A Multidisciplinary Approach
    • Glisson, B.1    Cango, M.2    Feigenberg, S.3
  • 4
    • 33748057486 scopus 로고    scopus 로고
    • Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear Factor-B signaling as characteristics of a high-risk head and neck squamous cell carcinoma
    • C.H. Chung, J.S. Parker, K. Ely, J. Carter, Y. Yi, and B.A. Murphy Gene expression profiles identify epithelial-to-mesenchymal transition and activation of nuclear Factor-B signaling as characteristics of a high-risk head and neck squamous cell carcinoma Cancer Res 66 16 2006 8210 8218
    • (2006) Cancer Res , vol.66 , Issue.16 , pp. 8210-8218
    • Chung, C.H.1    Parker, J.S.2    Ely, K.3    Carter, J.4    Yi, Y.5    Murphy, B.A.6
  • 5
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • J.P. Thiery Epithelial-mesenchymal transitions in tumour progression Nat Rev Cancer 2 6 2002 442 454
    • (2002) Nat Rev Cancer , vol.2 , Issue.6 , pp. 442-454
    • Thiery, J.P.1
  • 6
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • R. Kalluri, and R. Weinberg The basics of epithelial-mesenchymal transition J Clin Invest 119 6 2009 1420 1428
    • (2009) J Clin Invest , vol.119 , Issue.6 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.2
  • 7
    • 79960699816 scopus 로고    scopus 로고
    • Significance of tumor satellite variables in reflecting the epithelial-mesenchymal transition of tongue cancer
    • T. Yang, C. Wu, J. Ko, C. Wang, P. Lou, and Y. Chang Significance of tumor satellite variables in reflecting the epithelial-mesenchymal transition of tongue cancer Oral Oncol 47 8 2011 720 724
    • (2011) Oral Oncol , vol.47 , Issue.8 , pp. 720-724
    • Yang, T.1    Wu, C.2    Ko, J.3    Wang, C.4    Lou, P.5    Chang, Y.6
  • 8
    • 67650996754 scopus 로고    scopus 로고
    • Biomarkers for epithelial-mesenchymal transitions
    • M. Zeisberg, and E.G. Neilson Biomarkers for epithelial-mesenchymal transitions J Clin Invest 119 6 2009 1429 1437
    • (2009) J Clin Invest , vol.119 , Issue.6 , pp. 1429-1437
    • Zeisberg, M.1    Neilson, E.G.2
  • 10
    • 79960368115 scopus 로고    scopus 로고
    • Expression of E-Cadherin and Vimentin correlates with metastasis formation in head and neck squamous cell carcinoma patients
    • M.M. Nijkamp, P.N. Span, I.J. Hoogsteen, A.J. Van der Kogel, J.H. Kaanders, and J. Bussink Expression of E-Cadherin and Vimentin correlates with metastasis formation in head and neck squamous cell carcinoma patients Radiother Oncol 99 3 2011 344 348
    • (2011) Radiother Oncol , vol.99 , Issue.3 , pp. 344-348
    • Nijkamp, M.M.1    Span, P.N.2    Hoogsteen, I.J.3    Van Der Kogel, A.J.4    Kaanders, J.H.5    Bussink, J.6
  • 11
    • 0030470184 scopus 로고    scopus 로고
    • Expression of N-Cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion
    • S. Islam, T.E. Carey, G.T. Wolf, M.J. Wheelock, and K.R. Johnson Expression of N-Cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion J Cell Biol 135 6 1996 1643 1654
    • (1996) J Cell Biol , vol.135 , Issue.6 , pp. 1643-1654
    • Islam, S.1    Carey, T.E.2    Wolf, G.T.3    Wheelock, M.J.4    Johnson, K.R.5
  • 12
    • 0034695913 scopus 로고    scopus 로고
    • Exogenous expression of N-Cadherin in breast cancer cells induces cell migration, invasion, and metastasis
    • R.B. Hazan, G.R. Phillips, R.F. Qiao, L. Norton, and S.A. Aaronson Exogenous expression of N-Cadherin in breast cancer cells induces cell migration, invasion, and metastasis J Cell Biol 148 4 2000 779 790
    • (2000) J Cell Biol , vol.148 , Issue.4 , pp. 779-790
    • Hazan, R.B.1    Phillips, G.R.2    Qiao, R.F.3    Norton, L.4    Aaronson, S.A.5
  • 13
    • 53349101074 scopus 로고    scopus 로고
    • Inhibition of Aurora-A suppresses epithelial-mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells
    • X. Wan, Z. Long, M. Yan, J. Xu, L. Xia, and L. Liu Inhibition of Aurora-A suppresses epithelial-mesenchymal transition and invasion by downregulating MAPK in nasopharyngeal carcinoma cells Carcinogenesis 29 10 2008 1930 1937
    • (2008) Carcinogenesis , vol.29 , Issue.10 , pp. 1930-1937
    • Wan, X.1    Long, Z.2    Yan, M.3    Xu, J.4    Xia, L.5    Liu, L.6
  • 14
    • 4143093757 scopus 로고    scopus 로고
    • Invasion and metastasis of oral cancer cells require methylation of E-Cadherin and/or degradation of membranous β-catenin
    • Y. Kudo, S. Kitajima, I. Ogawa, M. Hiraoka, S. Sargolzaei, and M.R. Keikhaee Invasion and metastasis of oral cancer cells require methylation of E-Cadherin and/or degradation of membranous β-catenin Clin Cancer Res 10 16 2004 5455 5463
    • (2004) Clin Cancer Res , vol.10 , Issue.16 , pp. 5455-5463
    • Kudo, Y.1    Kitajima, S.2    Ogawa, I.3    Hiraoka, M.4    Sargolzaei, S.5    Keikhaee, M.R.6
  • 15
    • 0034607246 scopus 로고    scopus 로고
    • E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas
    • G. Tamura, J. Yin, S. Wang, A. Fleisher, T. Zou, and J.M. Abraham E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas JNCI J Natl Cancer Inst 92 7 2000 569 573
    • (2000) JNCI J Natl Cancer Inst , vol.92 , Issue.7 , pp. 569-573
    • Tamura, G.1    Yin, J.2    Wang, S.3    Fleisher, A.4    Zou, T.5    Abraham, J.M.6
  • 16
    • 0029114538 scopus 로고
    • Silencing of the E-Cadherin invasion-suppressor gene by CpG methylation in human carcinomas
    • K. Yoshiura, Y. Kanai, A. Ochiai, Y. Shimoyama, T. Sugimura, and S. Hirohashi Silencing of the E-Cadherin invasion-suppressor gene by CpG methylation in human carcinomas Proc Natl Acad Sci 92 16 1995 7416 7419
    • (1995) Proc Natl Acad Sci , vol.92 , Issue.16 , pp. 7416-7419
    • Yoshiura, K.1    Kanai, Y.2    Ochiai, A.3    Shimoyama, Y.4    Sugimura, T.5    Hirohashi, S.6
  • 17
    • 70349984001 scopus 로고    scopus 로고
    • P-Cadherin induces an epithelial-like phenotype in oral squamous cell carcinoma by GSK-3beta-mediated Snail phosphorylation
    • K. Bauer, A. Dowejko, A. Bosserhoff, T. Reichert, and R.J. Bauer P-Cadherin induces an epithelial-like phenotype in oral squamous cell carcinoma by GSK-3beta-mediated Snail phosphorylation Carcinogenesis 30 10 2009 1781 1788
    • (2009) Carcinogenesis , vol.30 , Issue.10 , pp. 1781-1788
    • Bauer, K.1    Dowejko, A.2    Bosserhoff, A.3    Reichert, T.4    Bauer, R.J.5
  • 18
    • 48249126269 scopus 로고    scopus 로고
    • Truncated P-Cadherin is produced in oral squamous cell carcinoma
    • R. Bauer, A. Dowejko, O. Driemel, A. Boßerhoff, and T.E. Reichert Truncated P-Cadherin is produced in oral squamous cell carcinoma FEBS J 275 16 2008 4198 4210
    • (2008) FEBS J , vol.275 , Issue.16 , pp. 4198-4210
    • Bauer, R.1    Dowejko, A.2    Driemel, O.3    Boßerhoff, A.4    Reichert, T.E.5
  • 19
    • 0347504931 scopus 로고    scopus 로고
    • Expression of P-Cadherin, but not E-Cadherin or N-Cadherin, relates to pathological and functional differentiation of breast carcinomas
    • A. Kovacs, J. Dhillon, and R. Walker Expression of P-Cadherin, but not E-Cadherin or N-Cadherin, relates to pathological and functional differentiation of breast carcinomas Mol Pathol 56 6 2003 318 322
    • (2003) Mol Pathol , vol.56 , Issue.6 , pp. 318-322
    • Kovacs, A.1    Dhillon, J.2    Walker, R.3
  • 20
    • 79952784665 scopus 로고    scopus 로고
    • N-Cadherin expression is involved in malignant behavior of head and neck cancer in relation to epithelial-mesenchymal transition
    • P. Nguyan, Y. Kudo, M. Yoshida, N. Kamata, I. Ogawa, and T. Takata N-Cadherin expression is involved in malignant behavior of head and neck cancer in relation to epithelial-mesenchymal transition Histol Histopathol 26 2 2011 147 156
    • (2011) Histol Histopathol , vol.26 , Issue.2 , pp. 147-156
    • Nguyan, P.1    Kudo, Y.2    Yoshida, M.3    Kamata, N.4    Ogawa, I.5    Takata, T.6
  • 21
    • 79952986583 scopus 로고    scopus 로고
    • Down-regulation of microRNAs of the miR-200 family and miR-205, and an altered expression of classic and desmosomal Cadherins in spindle cell carcinoma of the head and neck-hallmark of epithelial-mesenchymal transition
    • N. Zidar, E. Boštjančič, N. Gale, N. Kojc, M. Poljak, and D. Glavač Down-regulation of microRNAs of the miR-200 family and miR-205, and an altered expression of classic and desmosomal Cadherins in spindle cell carcinoma of the head and neck-hallmark of epithelial-mesenchymal transition Hum Pathol 42 4 2011 482 488
    • (2011) Hum Pathol , vol.42 , Issue.4 , pp. 482-488
    • Zidar, N.1    Boštjančič, E.2    Gale, N.3    Kojc, N.4    Poljak, M.5    Glavač, D.6
  • 22
    • 78650781453 scopus 로고    scopus 로고
    • N-Cadherin expression is correlated with metastasis of spindle cell carcinoma of head and neck region
    • P.T. Nguyen, Y. Kudo, M. Yoshida, S. Iizuka, I. Ogawa, and T. Takata N-Cadherin expression is correlated with metastasis of spindle cell carcinoma of head and neck region J Oral Pathol Med 40 1 2010 77 82
    • (2010) J Oral Pathol Med , vol.40 , Issue.1 , pp. 77-82
    • Nguyen, P.T.1    Kudo, Y.2    Yoshida, M.3    Iizuka, S.4    Ogawa, I.5    Takata, T.6
  • 23
    • 51749124653 scopus 로고    scopus 로고
    • Cadherin-catenin complex and transcription factor Snail-1 in spindle cell carcinoma of the head and neck
    • N. Zidar, N. Gale, N. Kojc, M. Volavsek, A. Cardesa, and L. Alos Cadherin-catenin complex and transcription factor Snail-1 in spindle cell carcinoma of the head and neck Virchows Archiv 453 3 2008 267 274
    • (2008) Virchows Archiv , vol.453 , Issue.3 , pp. 267-274
    • Zidar, N.1    Gale, N.2    Kojc, N.3    Volavsek, M.4    Cardesa, A.5    Alos, L.6
  • 24
    • 67349204350 scopus 로고    scopus 로고
    • Transcription factors Snail, Slug, Twist, and SIP1 in spindle cell carcinoma of the head and neck
    • N. Kojc, N. Zidar, N. Gale, M. Poljak, K. Komlos, and A. Cardesa Transcription factors Snail, Slug, Twist, and SIP1 in spindle cell carcinoma of the head and neck Virchows Archiv 454 5 2009 549 555
    • (2009) Virchows Archiv , vol.454 , Issue.5 , pp. 549-555
    • Kojc, N.1    Zidar, N.2    Gale, N.3    Poljak, M.4    Komlos, K.5    Cardesa, A.6
  • 25
    • 84055176150 scopus 로고    scopus 로고
    • Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression
    • J. Haynes, J. Srivastava, N. Madson, T. Wittman, and D.L. Barber Dynamic actin remodeling during epithelial-mesenchymal transition depends on increased moesin expression Mol Biol Cell 22 24 2011 4750 4764
    • (2011) Mol Biol Cell , vol.22 , Issue.24 , pp. 4750-4764
    • Haynes, J.1    Srivastava, J.2    Madson, N.3    Wittman, T.4    Barber, D.L.5
  • 26
    • 68049133177 scopus 로고    scopus 로고
    • Galpha12-mediated pathway promotes invasiveness of nasopharyngeal carcinoma by modulating actin cytoskeleton reorganization
    • S. Liu, Y. Jen, S.S. Jiang, J. Chang, C.A. Hsiung, and C. Wang Galpha12-mediated pathway promotes invasiveness of nasopharyngeal carcinoma by modulating actin cytoskeleton reorganization Cancer Res 69 15 2009 6122 6130
    • (2009) Cancer Res , vol.69 , Issue.15 , pp. 6122-6130
    • Liu, S.1    Jen, Y.2    Jiang, S.S.3    Chang, J.4    Hsiung, C.A.5    Wang, C.6
  • 27
    • 70350335625 scopus 로고    scopus 로고
    • Effects of small interfering RNAs targeting Fascin on gene expression in oral cancer cells
    • S. Chen, C. Lin, Y. Chang, J. Li, E. Fu, and F. Chang Effects of small interfering RNAs targeting Fascin on gene expression in oral cancer cells J Oral Pathol Med 38 9 2009 722 730
    • (2009) J Oral Pathol Med , vol.38 , Issue.9 , pp. 722-730
    • Chen, S.1    Lin, C.2    Chang, Y.3    Li, J.4    Fu, E.5    Chang, F.6
  • 28
    • 0024786778 scopus 로고
    • Basement membranes: Molecular organization and function in development and disease
    • J. Schittny, and P. Yurchenco Basement membranes: molecular organization and function in development and disease Curr Opin Cell Biol 1 5 1989 983 988
    • (1989) Curr Opin Cell Biol , vol.1 , Issue.5 , pp. 983-988
    • Schittny, J.1    Yurchenco, P.2
  • 29
    • 50249168739 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition downregulates laminin α5 chain and upregulates laminin α4 chain in oral squamous carcinoma cells
    • M. Takkunen, M. Ainola, N. Vainionpää, R. Grenman, M. Patarroyo, and A. García de Herreros Epithelial-mesenchymal transition downregulates laminin α5 chain and upregulates laminin α4 chain in oral squamous carcinoma cells Histochem Cell Biol 130 3 2008 509 525
    • (2008) Histochem Cell Biol , vol.130 , Issue.3 , pp. 509-525
    • Takkunen, M.1    Ainola, M.2    Vainionpää, N.3    Grenman, R.4    Patarroyo, M.5    García De Herreros, A.6
  • 30
    • 0037066685 scopus 로고    scopus 로고
    • The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer
    • Y.-S. Dai, and P. Cserjesi The basic helix-loop-helix factor, HAND2, functions as a transcriptional activator by binding to E-boxes as a heterodimer J Biol Chem 277 15 2002 12604 12612
    • (2002) J Biol Chem , vol.277 , Issue.15 , pp. 12604-12612
    • Dai, Y.-S.1    Cserjesi, P.2
  • 31
    • 0037086277 scopus 로고    scopus 로고
    • The SLUG zinc-finger protein represses E-Cadherin in breast cancer
    • K.M. Hajra, D.Y.-S. Chen, and E.R. Fearon The SLUG zinc-finger protein represses E-Cadherin in breast cancer Cancer Res 62 6 2002 1613 1618
    • (2002) Cancer Res , vol.62 , Issue.6 , pp. 1613-1618
    • Hajra, K.M.1    Chen, D.Y.-S.2    Fearon, E.R.3
  • 32
    • 38349023012 scopus 로고    scopus 로고
    • Twist is a transcriptional repressor of E-Cadherin gene expression in breast cancer
    • F. Vesuna, P. van Diest, J.H. Chen, and V. Raman Twist is a transcriptional repressor of E-Cadherin gene expression in breast cancer Biochem Biophys Res Commun 367 2 2008 235 241
    • (2008) Biochem Biophys Res Commun , vol.367 , Issue.2 , pp. 235-241
    • Vesuna, F.1    Van Diest, P.2    Chen, J.H.3    Raman, V.4
  • 33
    • 77949569896 scopus 로고    scopus 로고
    • Expression of c-kit and Slug correlates with invasion and metastasis of salivary adenoid cystic carcinoma
    • Y. Tang, X. Liang, M. Zheng, Z. Zhu, G. Zhu, and J. Yang Expression of c-kit and Slug correlates with invasion and metastasis of salivary adenoid cystic carcinoma Oral Oncol 46 4 2010 311 316
    • (2010) Oral Oncol , vol.46 , Issue.4 , pp. 311-316
    • Tang, Y.1    Liang, X.2    Zheng, M.3    Zhu, Z.4    Zhu, G.5    Yang, J.6
  • 34
    • 80051494453 scopus 로고    scopus 로고
    • Twist and snai1 expression in pharyngeal squamous cell carcinoma stroma is related to cancer progression
    • A. Jouppila-Mättö, M. Närkiö-Mäkelä, Y. Soini, M. Pukkila, R. Sironen, and H. Tuhkanen Twist and snai1 expression in pharyngeal squamous cell carcinoma stroma is related to cancer progression BMC Cancer 11 1 2011 350
    • (2011) BMC Cancer , vol.11 , Issue.1 , pp. 350
    • Jouppila-Mättö, A.1    Närkiö-Mäkelä, M.2    Soini, Y.3    Pukkila, M.4    Sironen, R.5    Tuhkanen, H.6
  • 35
    • 79959393307 scopus 로고    scopus 로고
    • The potential for LOXL2 as a target for future cancer treatment
    • H.E. Barker, and J.T. Erler The potential for LOXL2 as a target for future cancer treatment Future Oncol 7 6 2011 707 710
    • (2011) Future Oncol , vol.7 , Issue.6 , pp. 707-710
    • Barker, H.E.1    Erler, J.T.2
  • 37
    • 77950391697 scopus 로고    scopus 로고
    • Stat3 orchestrates tumor development and progression: The Achilles' heel of head and neck cancers?
    • M. Masuda, T. Wakasaki, M. Suzui, S. Toh, A.K. Joe, and I.B. Weinstein Stat3 orchestrates tumor development and progression: the Achilles' heel of head and neck cancers? Curr Cancer Drug Targets 10 1 2010 117 126
    • (2010) Curr Cancer Drug Targets , vol.10 , Issue.1 , pp. 117-126
    • Masuda, M.1    Wakasaki, T.2    Suzui, M.3    Toh, S.4    Joe, A.K.5    Weinstein, I.B.6
  • 38
    • 79955780958 scopus 로고    scopus 로고
    • IL-6 stabilizes Twist and enhances tumor cell motility in head and neck cancer cells through activation of casein Kinase 2
    • Y. Su, T. Xie, D. Sano, and J.N. Myers IL-6 stabilizes Twist and enhances tumor cell motility in head and neck cancer cells through activation of casein Kinase 2 Plos One 6 4 2011 e19412
    • (2011) Plos One , vol.6 , Issue.4 , pp. 19412
    • Su, Y.1    Xie, T.2    Sano, D.3    Myers, J.N.4
  • 39
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • S.A. Mani, W. Guo, M. Liao, E.N. Eaton, A. Ayyanan, and A.Y. Zhou The epithelial-mesenchymal transition generates cells with properties of stem cells Cell 133 4 2008 704 715
    • (2008) Cell , vol.133 , Issue.4 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.3    Eaton, E.N.4    Ayyanan, A.5    Zhou, A.Y.6
  • 41
    • 27844461512 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in development and cancer: Role of phosphatidylinositol 3′ kinase/AKT pathways
    • L. Larue, and A. Bellacosa Epithelial-mesenchymal transition in development and cancer: role of phosphatidylinositol 3′ kinase/AKT pathways Oncogene 24 50 2005 7443 7454
    • (2005) Oncogene , vol.24 , Issue.50 , pp. 7443-7454
    • Larue, L.1    Bellacosa, A.2
  • 42
    • 61849112651 scopus 로고    scopus 로고
    • Inhibition of Akt activity induces the mesenchymal-to-epithelial reverting transition with restoring E-Cadherin expression in KB and KOSCC-25B oral squamous cell carcinoma cells
    • K. Hong, J. Kim, J. Hong, H. Yoon, J. Lee, and S. Hong Inhibition of Akt activity induces the mesenchymal-to-epithelial reverting transition with restoring E-Cadherin expression in KB and KOSCC-25B oral squamous cell carcinoma cells J Exp Clin Cancer Res 28 1 2009 28
    • (2009) J Exp Clin Cancer Res , vol.28 , Issue.1 , pp. 28
    • Hong, K.1    Kim, J.2    Hong, J.3    Yoon, H.4    Lee, J.5    Hong, S.6
  • 43
    • 72849130207 scopus 로고    scopus 로고
    • The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells
    • L. Song, J. Li, W. Liao, Y. Feng, C. Yu, and L. Hu The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells J Clin Invest 119 12 2009 3626 3636
    • (2009) J Clin Invest , vol.119 , Issue.12 , pp. 3626-3636
    • Song, L.1    Li, J.2    Liao, W.3    Feng, Y.4    Yu, C.5    Hu, L.6
  • 44
    • 40749129288 scopus 로고    scopus 로고
    • Transforming growth factor-1 promotes matrix metalloproteinase-9 mediated oral cancer invasion through Snail expression
    • L. Sun, M.E. Diamond, A.J. Ottaviano, M.J. Joseph, V. Ananthanarayan, and H.G. Munshi Transforming growth factor-1 promotes matrix metalloproteinase-9 mediated oral cancer invasion through Snail expression Mol Cancer Res 6 1 2008 10 20
    • (2008) Mol Cancer Res , vol.6 , Issue.1 , pp. 10-20
    • Sun, L.1    Diamond, M.E.2    Ottaviano, A.J.3    Joseph, M.J.4    Ananthanarayan, V.5    Munshi, H.G.6
  • 45
    • 77956533018 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in oral squamous cell carcinoma triggered by transforming growth factor-β1 is Snail family-dependent and correlates with matrix metalloproteinase-2 and -9 expressions
    • B. Qiao, N.W. Johnson, and J. Gao Epithelial-mesenchymal transition in oral squamous cell carcinoma triggered by transforming growth factor-β1 is Snail family-dependent and correlates with matrix metalloproteinase-2 and -9 expressions Int J Oncol 37 3 2010
    • (2010) Int J Oncol , vol.37 , Issue.3
    • Qiao, B.1    Johnson, N.W.2    Gao, J.3
  • 46
    • 22244471785 scopus 로고    scopus 로고
    • Matrix metalloproteases and epithelial-to-mesenchymal transition: Implications for carcinoma metastasis
    • Austin (TX): Landes Bioscience
    • Gilles C, Newgreen DF, Sato H, Thompson EW. Matrix Metalloproteases and Epithelial-to-mesenchymal Transition: Implications for Carcinoma Metastasis. Madame Curie Bioscience Database [Internet]. Austin (TX): Landes Bioscience; 2000.
    • (2000) Madame Curie Bioscience Database [Internet]
    • Gilles, C.1    Newgreen, D.F.2    Sato, H.3    Thompson, E.W.4
  • 47
    • 47549089080 scopus 로고    scopus 로고
    • Matrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor development
    • L.S. Orlichenko, and D.C. Radisky Matrix metalloproteinases stimulate epithelial-mesenchymal transition during tumor development Clin Exp Metast 25 6 2008 593 600
    • (2008) Clin Exp Metast , vol.25 , Issue.6 , pp. 593-600
    • Orlichenko, L.S.1    Radisky, D.C.2
  • 48
    • 70350143237 scopus 로고    scopus 로고
    • Slug is a downstream mediator of transforming growth factor-β1- induced matrix metalloproteinase-9 expression and invasion of oral cancer cells
    • M.J. Joseph, S. Dangi-Garimella, M.A. Shields, M.E. Diamond, L. Sun, and J.E. Koblinski Slug is a downstream mediator of transforming growth factor-β1-induced matrix metalloproteinase-9 expression and invasion of oral cancer cells J Cell Biochem 108 3 2009 726 736
    • (2009) J Cell Biochem , vol.108 , Issue.3 , pp. 726-736
    • Joseph, M.J.1    Dangi-Garimella, S.2    Shields, M.A.3    Diamond, M.E.4    Sun, L.5    Koblinski, J.E.6
  • 50
    • 80054000870 scopus 로고    scopus 로고
    • The Smad family and its role in pancreatic cancer
    • P. Singh, R. Srinivasan, and J. Wig The Smad family and its role in pancreatic cancer Indian J Cancer 48 3 2011 351
    • (2011) Indian J Cancer , vol.48 , Issue.3 , pp. 351
    • Singh, P.1    Srinivasan, R.2    Wig, J.3
  • 51
    • 77951989582 scopus 로고    scopus 로고
    • Smad2 and Smad6 as predictors of overall survival in oral squamous cell carcinoma patients
    • F.R. Mangone, F. Walder, S. Maistro, F.S. Pasini, C.N. Lehn, and M.B. Carvalho Smad2 and Smad6 as predictors of overall survival in oral squamous cell carcinoma patients Mol Cancer 9 1 2010 106
    • (2010) Mol Cancer , vol.9 , Issue.1 , pp. 106
    • Mangone, F.R.1    Walder, F.2    Maistro, S.3    Pasini, F.S.4    Lehn, C.N.5    Carvalho, M.B.6
  • 52
    • 53249130662 scopus 로고    scopus 로고
    • Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers
    • M. Sabbah, S. Emami, G. Redeuilh, S. Julien, G. Prevost, and A. Zimber Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers Drug Resist Updates 11 4-5 2008 123 151
    • (2008) Drug Resist Updates , vol.11 , Issue.45 , pp. 123-151
    • Sabbah, M.1    Emami, S.2    Redeuilh, G.3    Julien, S.4    Prevost, G.5    Zimber, A.6
  • 53
    • 84857715049 scopus 로고    scopus 로고
    • Epidermal growth factor receptor protein detection in head and neck cancer patients: A many-faceted picture
    • J. Thariat, M. Etienne-Grimaldi, D. Grail, R. Bensadoun, A. Cayre, and F. Penault-Liorca Epidermal growth factor receptor protein detection in head and neck cancer patients: a many-faceted picture Clin Cancer Res 18 5 2012 1313 1322
    • (2012) Clin Cancer Res , vol.18 , Issue.5 , pp. 1313-1322
    • Thariat, J.1    Etienne-Grimaldi, M.2    Grail, D.3    Bensadoun, R.4    Cayre, A.5    Penault-Liorca, F.6
  • 54
    • 23144442645 scopus 로고    scopus 로고
    • Regulation of Cadherin-mediated adhesion in morphogenesis
    • B.M. Gumbiner Regulation of Cadherin-mediated adhesion in morphogenesis Nat Rev Mol Cell Biol 6 8 2005 622 634
    • (2005) Nat Rev Mol Cell Biol , vol.6 , Issue.8 , pp. 622-634
    • Gumbiner, B.M.1
  • 55
    • 47549092230 scopus 로고    scopus 로고
    • Bypassing cellular EGF receptor dependence through epithelial-to- mesenchymal-like transitions
    • S. Barr, S. Thomson, E. Buck, S. Russo, F. Petti, and I. Sujka-Kwok Bypassing cellular EGF receptor dependence through epithelial-to-mesenchymal- like transitions Clin Exp Metast 25 6 2008 685 693
    • (2008) Clin Exp Metast , vol.25 , Issue.6 , pp. 685-693
    • Barr, S.1    Thomson, S.2    Buck, E.3    Russo, S.4    Petti, F.5    Sujka-Kwok, I.6
  • 56
    • 84860389234 scopus 로고    scopus 로고
    • Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing EMT-like phenotype change and MMP-9-mediated degradation of E-Cadherin
    • J. Zuo, W. Zhu, M. Li, X. Li, H. Yi, and G. Zeng Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing EMT-like phenotype change and MMP-9-mediated degradation of E-Cadherin J Cell Biochem 112 9 2011 2508 2517
    • (2011) J Cell Biochem , vol.112 , Issue.9 , pp. 2508-2517
    • Zuo, J.1    Zhu, W.2    Li, M.3    Li, X.4    Yi, H.5    Zeng, G.6
  • 57
    • 80655149151 scopus 로고    scopus 로고
    • Epithelial-mesenchymal-transition induced by EGFR activation interferes with cell migration and response to irradiation and cetuximab in head and neck cancer cells
    • C. Holz, F. Niehr, M. Boyko, T. Hristozova, L. Distel, and V. Budach Epithelial-mesenchymal-transition induced by EGFR activation interferes with cell migration and response to irradiation and cetuximab in head and neck cancer cells Radiother Oncol 101 1 2011 158 164
    • (2011) Radiother Oncol , vol.101 , Issue.1 , pp. 158-164
    • Holz, C.1    Niehr, F.2    Boyko, M.3    Hristozova, T.4    Distel, L.5    Budach, V.6
  • 58
    • 4344680669 scopus 로고    scopus 로고
    • Epidermal growth factor receptor inhibition promotes desmosome assembly and strengthens intercellular adhesion in squamous cell carcinoma cells
    • J.H. Lorch, J. Klessner, J. Park, S. Getsios, Y. Wu, and M. Stack Epidermal growth factor receptor inhibition promotes desmosome assembly and strengthens intercellular adhesion in squamous cell carcinoma cells J Biol Chem 279 35 2004 37191 37200
    • (2004) J Biol Chem , vol.279 , Issue.35 , pp. 37191-37200
    • Lorch, J.H.1    Klessner, J.2    Park, J.3    Getsios, S.4    Wu, Y.5    Stack, M.6
  • 59
    • 78650767258 scopus 로고    scopus 로고
    • EGF/TGFβ1 co-stimulation of oral squamous cell carcinoma cells causes an epithelial-mesenchymal transition cell phenotype expressing laminin 332
    • P. Richter, C. Umbreit, M. Franz, A. Berndt, S. Grimm, and A. Vecker EGF/TGFβ1 co-stimulation of oral squamous cell carcinoma cells causes an epithelial-mesenchymal transition cell phenotype expressing laminin 332 J Oral Pathol Med 40 1 2011 46 54
    • (2011) J Oral Pathol Med , vol.40 , Issue.1 , pp. 46-54
    • Richter, P.1    Umbreit, C.2    Franz, M.3    Berndt, A.4    Grimm, S.5    Vecker, A.6
  • 60
    • 33644698049 scopus 로고    scopus 로고
    • Correlations of oral tongue cancer invasion with matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) expression
    • S. Kim, N.H. Cho, K. Kim, J.S. Lee, B.S. Koo, and J.H. Kim Correlations of oral tongue cancer invasion with matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) expression J Surg Oncol 93 4 2006 330 337
    • (2006) J Surg Oncol , vol.93 , Issue.4 , pp. 330-337
    • Kim, S.1    Cho, N.H.2    Kim, K.3    Lee, J.S.4    Koo, B.S.5    Kim, J.H.6
  • 61
    • 77954860342 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cancer: Parallels between normal development and tumor progression
    • D.S. Micalizzi, S.M. Farabaugh, and H.L. Ford Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression J Mammary Gland Biol Neoplasia 15 2 2010 117 134
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , Issue.2 , pp. 117-134
    • Micalizzi, D.S.1    Farabaugh, S.M.2    Ford, H.L.3
  • 63
    • 76849086904 scopus 로고    scopus 로고
    • Transcriptional induction of MMP-10 by TGF-β, mediated by activation of MEF2A and downregulation of class IIa HDACs
    • F. Ishikawa, H. Miyoshi, K. Nose, and M. Shibanuma Transcriptional induction of MMP-10 by TGF-β, mediated by activation of MEF2A and downregulation of class IIa HDACs Oncogene 29 6 2009 909 919
    • (2009) Oncogene , vol.29 , Issue.6 , pp. 909-919
    • Ishikawa, F.1    Miyoshi, H.2    Nose, K.3    Shibanuma, M.4
  • 64
    • 77950867351 scopus 로고    scopus 로고
    • TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma
    • M.E. Kupferman, T. Jiffar, A. El-Naggar, T. Yilmaz, G. Zhou, and T. Xie TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma Oncogene 29 14 2010 2047 2059
    • (2010) Oncogene , vol.29 , Issue.14 , pp. 2047-2059
    • Kupferman, M.E.1    Jiffar, T.2    El-Naggar, A.3    Yilmaz, T.4    Zhou, G.5    Xie, T.6
  • 65
    • 79551687100 scopus 로고    scopus 로고
    • Fibroblasts produce brain-derived neurotrophic factor and induce mesenchymal transition of oral tumor cells
    • J. Dudás, M. Bitsche, V. Schartinger, C. Falkeis, G.M. Sprinzl, and H. Riechelmann Fibroblasts produce brain-derived neurotrophic factor and induce mesenchymal transition of oral tumor cells Oral Oncol 47 2 2011 98 103
    • (2011) Oral Oncol , vol.47 , Issue.2 , pp. 98-103
    • Dudás, J.1    Bitsche, M.2    Schartinger, V.3    Falkeis, C.4    Sprinzl, G.M.5    Riechelmann, H.6
  • 66
    • 79957534572 scopus 로고    scopus 로고
    • Targeting hypoxia in cancer therapy
    • W. Wilson, and M. Hay Targeting hypoxia in cancer therapy Nat Rev Cancer 11 6 2011 393 410
    • (2011) Nat Rev Cancer , vol.11 , Issue.6 , pp. 393-410
    • Wilson, W.1    Hay, M.2
  • 67
    • 40249113328 scopus 로고    scopus 로고
    • Direct regulation of TWIST by HIF-1α promotes metastasis
    • M. Yang, M. Wu, S. Chiou, P. Chen, S. Chang, and C. Liu Direct regulation of TWIST by HIF-1α promotes metastasis Nat Cell Biol 10 3 2008 295 305
    • (2008) Nat Cell Biol , vol.10 , Issue.3 , pp. 295-305
    • Yang, M.1    Wu, M.2    Chiou, S.3    Chen, P.4    Chang, S.5    Liu, C.6
  • 68
    • 79551685392 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 alpha, in association with TWIST2 and SNIP1, is a critical prognostic factor in patients with tongue squamous cell carcinoma
    • X. Liang, M. Zheng, J. Jiang, G. Zhu, J. Yang, and Y. Tang Hypoxia-inducible factor-1 alpha, in association with TWIST2 and SNIP1, is a critical prognostic factor in patients with tongue squamous cell carcinoma Oral Oncol 47 2 2011 92 97
    • (2011) Oral Oncol , vol.47 , Issue.2 , pp. 92-97
    • Liang, X.1    Zheng, M.2    Jiang, J.3    Zhu, G.4    Yang, J.5    Tang, Y.6
  • 69
    • 77957583439 scopus 로고    scopus 로고
    • Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition
    • M. Yang, D.S. Hsu, H. Wang, H. Wang, H. Lan, and W. Yang Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition Nat Cell Biol 12 10 2010 982 992
    • (2010) Nat Cell Biol , vol.12 , Issue.10 , pp. 982-992
    • Yang, M.1    Hsu, D.S.2    Wang, H.3    Wang, H.4    Lan, H.5    Yang, W.6
  • 70
    • 72949099284 scopus 로고    scopus 로고
    • Regulation of membrane-type 4 matrix metalloproteinase by SLUG contributes to hypoxia-mediated metastasis
    • H. Chi-Hung, Y. Wen-Hao, C. Shyue-Yih, T. Shyh-Kuan, T. Cheng-Hwei, and K. Jung-Yie Regulation of membrane-type 4 matrix metalloproteinase by SLUG contributes to hypoxia-mediated metastasis Neoplasia 11 12 2009 1371 1382
    • (2009) Neoplasia , vol.11 , Issue.12 , pp. 1371-1382
    • Chi-Hung, H.1    Wen-Hao, Y.2    Shyue-Yih, C.3    Shyh-Kuan, T.4    Cheng-Hwei, T.5    Jung-Yie, K.6
  • 71
    • 0033017066 scopus 로고    scopus 로고
    • Expression of proinflammatory and proangiogenic cytokines in patients with head and neck cancer
    • Z. Chen, P.S. Malhotra, G.R. Thomas, F.G. Ondrey, D.C. Duffey, and C.W. Smith Expression of proinflammatory and proangiogenic cytokines in patients with head and neck cancer Clin Cancer Res 5 6 1999 1369 1379
    • (1999) Clin Cancer Res , vol.5 , Issue.6 , pp. 1369-1379
    • Chen, Z.1    Malhotra, P.S.2    Thomas, G.R.3    Ondrey, F.G.4    Duffey, D.C.5    Smith, C.W.6
  • 72
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • J.P. Thiery, H. Acloque, R.Y. Huang, and M.A. Nieto Epithelial- mesenchymal transitions in development and disease Cell 139 5 2009 871 890
    • (2009) Cell , vol.139 , Issue.5 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 73
    • 84055207487 scopus 로고    scopus 로고
    • IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway
    • A. Yadav, B. Kumar, J. Datta, T. Teknos, and P. Kumar IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway Mol Cancer Res 9 12 2011 1658 1667
    • (2011) Mol Cancer Res , vol.9 , Issue.12 , pp. 1658-1667
    • Yadav, A.1    Kumar, B.2    Datta, J.3    Teknos, T.4    Kumar, P.5
  • 75
    • 70349694379 scopus 로고    scopus 로고
    • Proinflammatory mediators upregulate Snail in head and neck squamous cell carcinoma
    • M.A. St. John, M. Dohadwala, J. Luo, G. Wang, G. Lee, and H. Shih Proinflammatory mediators upregulate Snail in head and neck squamous cell carcinoma Clin Cancer Res 15 19 2009 6018 6027
    • (2009) Clin Cancer Res , vol.15 , Issue.19 , pp. 6018-6027
    • St. John, M.A.1    Dohadwala, M.2    Luo, J.3    Wang, G.4    Lee, G.5    Shih, H.6
  • 76
    • 10044248559 scopus 로고    scopus 로고
    • Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity
    • M.L. Gillison Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity Semin Oncol 31 6 2004 744 754
    • (2004) Semin Oncol , vol.31 , Issue.6 , pp. 744-754
    • Gillison, M.L.1
  • 77
    • 77954575776 scopus 로고    scopus 로고
    • Sonic hedgehog acts as a negative regulator of β-Catenin signaling in the adult tongue epithelium
    • F.T. Schneider, A. Schanzer, C.J. Czupalla, S. Thom, K. Engels, and M.H. Schmidt Sonic hedgehog acts as a negative regulator of β-Catenin signaling in the adult tongue epithelium Am J Pathol 177 1 2010 404 414
    • (2010) Am J Pathol , vol.177 , Issue.1 , pp. 404-414
    • Schneider, F.T.1    Schanzer, A.2    Czupalla, C.J.3    Thom, S.4    Engels, K.5    Schmidt, M.H.6


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