메뉴 건너뛰기




Volumn 19, Issue 27, 2012, Pages 4662-4670

Proteomics to unravel platelet-related diseases and identify novel anti-platelet drugs

Author keywords

Biomarkers; Diagnosis; Drug; Gel based techniques; Mass spectrometry; Molecular mechanisms; Platelet disorders; Platelets; Proteomics; Therapeutic target

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE TRIPHOSPHATE; BIOLOGICAL MARKER; BLOOD CLOTTING FACTOR 13A; CD40 LIGAND; CILOSTAZOL; CYCLIC AMP; CYTOSKELETON PROTEIN; DASATINIB; FIBRINOGEN; GLYCOPROTEIN VI; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; RADIXIN; RGS2 PROTEIN; ROSUVASTATIN; TESTOSTERONE 17BETA DEHYDROGENASE; THROMBOSPONDIN 1; ANTITHROMBOCYTIC AGENT; PROTEOME;

EID: 84875268207     PISSN: 09298673     EISSN: 1875533X     Source Type: Journal    
DOI: 10.2174/092986712803306312     Document Type: Article
Times cited : (10)

References (67)
  • 1
    • 77950635286 scopus 로고    scopus 로고
    • Basic principles of platelet biology and clinical implications
    • Angiolillo, D.J.; Ueno, M.; Goto, S. Basic principles of platelet biology and clinical implications. Circ. J., 2010, 74(4), 597-607.
    • (2010) Circ. J , vol.74 , Issue.4 , pp. 597-607
    • Angiolillo, D.J.1    Ueno, M.2    Goto, S.3
  • 2
    • 79959835681 scopus 로고    scopus 로고
    • Role of platelets and antiplatelet therapy in cardiovascular disease
    • Ueno, M.; Kodali, M.; Tello-Montoliu, A.; Angiolillo, D.J. Role of platelets and antiplatelet therapy in cardiovascular disease. J. Atheroscler. Thromb., 2011, 18(6), 431-442.
    • (2011) J. Atheroscler. Thromb , vol.18 , Issue.6 , pp. 431-442
    • Ueno, M.1    Kodali, M.2    Tello-Montoliu, A.3    Angiolillo, D.J.4
  • 3
    • 37249068049 scopus 로고    scopus 로고
    • Platelet activation and atherothrombosis
    • Davi', G.; Patrono, C. Platelet activation and atherothrombosis. N Engl J Med 2007, 357, 2482-94.
    • (2007) N Engl J Med , vol.357 , pp. 2482-2494
    • Davi, G.1    Patrono, C.2
  • 5
    • 0032875697 scopus 로고    scopus 로고
    • Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
    • Gygi, S.P.; Rist, B.; Gerber, S.A.; Turecek, F.; Gelb, M.H.; Aebersold, R. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nat. Biotechnol., 1999, 17, 994-999.
    • (1999) Nat. Biotechnol , vol.17 , pp. 994-999
    • Gygi, S.P.1    Rist, B.2    Gerber, S.A.3    Turecek, F.4    Gelb, M.H.5    Aebersold, R.6
  • 8
    • 33845491463 scopus 로고    scopus 로고
    • Proteomic approaches to dissect platelet function: Half the story
    • Gnatenko, D.V.; Perrotta, P.L.; Bahou, W.F. Proteomic approaches to dissect platelet function: Half the story. Blood, 2006, 108(13), 3983-3991.
    • (2006) Blood , vol.108 , Issue.13 , pp. 3983-3991
    • Gnatenko, D.V.1    Perrotta, P.L.2    Bahou, W.F.3
  • 11
    • 51849147909 scopus 로고    scopus 로고
    • The value of proteomics for the diagnosis of a platelet-related bleeding disorder
    • Maurer-Spurej, E.; Kahr, W.H.; Carter, C.J.; Pittendreigh, C.; Cameron, M.; Cyr T.D. The value of proteomics for the diagnosis of a platelet-related bleeding disorder. Platelets, 2008, 19(5), 342-351.
    • (2008) Platelets , vol.19 , Issue.5 , pp. 342-351
    • Maurer-Spurej, E.1    Kahr, W.H.2    Carter, C.J.3    Pittendreigh, C.4    Cameron, M.5    Cyr, T.D.6
  • 12
    • 0035880246 scopus 로고    scopus 로고
    • Platelets from patients with the Quebec platelet disorder contain and secrete abnormal amounts of urokinasetype plasminogen activator
    • Kahr, W.H.; Zheng, S.; Sheth, P.M.; Pai, M.; Cowie, A.; Bouchard, M.; Podor, T.J.; Rivard, G.E.; Hayward, C.P. Platelets from patients with the Quebec platelet disorder contain and secrete abnormal amounts of urokinasetype plasminogen activator. Blood, 2001, 98(2), 257-265.
    • (2001) Blood , vol.98 , Issue.2 , pp. 257-265
    • Kahr, W.H.1    Zheng, S.2    Sheth, P.M.3    Pai, M.4    Cowie, A.5    Bouchard, M.6    Podor, T.J.7    Rivard, G.E.8    Hayward, C.P.9
  • 13
    • 61849180824 scopus 로고    scopus 로고
    • Quebec platelet disorder is linked to the urokinase plasminogen activator gene (PLAU) and increases expression of the linked allele in megakaryocytes
    • Diamandis, M.; Paterson, A.D.; Rommens, J.M.; Veljkovic, D.K.; Blavignac, J.; Bulman, D.E.; Waye, J.S.; Derome, F.; Rivard, G.E.; Hayward, C.P. Quebec platelet disorder is linked to the urokinase plasminogen activator gene (PLAU) and increases expression of the linked allele in megakaryocytes. Blood, 2009, 113(7), 1543-1546.
    • (2009) Blood , vol.113 , Issue.7 , pp. 1543-1546
    • Diamandis, M.1    Paterson, A.D.2    Rommens, J.M.3    Veljkovic, D.K.4    Blavignac, J.5    Bulman, D.E.6    Waye, J.S.7    Derome, F.8    Rivard, G.E.9    Hayward, C.P.10
  • 14
    • 77949516918 scopus 로고    scopus 로고
    • Persons with Quebec platelet disorder have a tandem duplication of PLAU, the urokinase plasminogen activator gene
    • Paterson, A.D.; Rommens, J.M.; Bharaj, B.; Blavignac, J.; Wong, I.; Diamandis, M.; Waye, J.S.; Rivard G.E.; Hayward, C.P. Persons with Quebec platelet disorder have a tandem duplication of PLAU, the urokinase plasminogen activator gene. Blood, 2010, 115(6), 1264-1266.
    • (2010) Blood , vol.115 , Issue.6 , pp. 1264-1266
    • Paterson, A.D.1    Rommens, J.M.2    Bharaj, B.3    Blavignac, J.4    Wong, I.5    Diamandis, M.6    Waye, J.S.7    Rivard, G.E.8    Hayward, C.P.9
  • 15
    • 77958539006 scopus 로고    scopus 로고
    • The α-granule proteome: Novel proteins in normal and ghost granules in gray platelet syndrome
    • Maynard, D.M.; Heijnen, H.F.; Gahl, W.A.; Gunay-Aygun, M. The α-granule proteome: novel proteins in normal and ghost granules in gray platelet syndrome. J. Thromb. Haemost., 2010, 8(8), 1786-1796.
    • (2010) J. Thromb. Haemost , vol.8 , Issue.8 , pp. 1786-1796
    • Maynard, D.M.1    Heijnen, H.F.2    Gahl, W.A.3    Gunay-Aygun, M.4
  • 19
    • 18544374500 scopus 로고    scopus 로고
    • The actin cytoskeleton differentially regulates platelet alpha-granule and dense-granule secretion
    • Flaumenhaft, R.; Dilks, J.R.; Rozenvayn, N.; Monahan-Earley, R.A.; Feng, D.; Dvorak, A.M. The actin cytoskeleton differentially regulates platelet alpha-granule and dense-granule secretion. Blood, 2005, 105(10), 3879-3887.
    • (2005) Blood , vol.105 , Issue.10 , pp. 3879-3887
    • Flaumenhaft, R.1    Dilks, J.R.2    Rozenvayn, N.3    Monahan-Earley, R.A.4    Feng, D.5    Dvorak, A.M.6
  • 22
    • 37349018834 scopus 로고    scopus 로고
    • Alternative translation initiation of human regulators of G-protein signaling-2 yields a set of functionally distinct proteins
    • Gu, S.; Anton, A.; Salim, S.; Blumer, K.J.; Dessauer, C.W.; Heximer, S.P. Alternative translation initiation of human regulators of G-protein signaling-2 yields a set of functionally distinct proteins. Mol. Pharmacol., 2008, 73(1), 1-11.
    • (2008) Mol. Pharmacol , vol.73 , Issue.1 , pp. 1-11
    • Gu, S.1    Anton, A.2    Salim, S.3    Blumer, K.J.4    Dessauer, C.W.5    Heximer, S.P.6
  • 23
    • 28844492181 scopus 로고    scopus 로고
    • Mechanisms of organelle transport and capture along proplatelets during platelet production
    • Richardson, J.L.; Shivdasani, R.A.; Boers, C.; Hartwig, J.H.; Italiano, J.E. Jr. Mechanisms of organelle transport and capture along proplatelets during platelet production. Blood, 2005, 106(13), 4066-7405.
    • (2005) Blood , vol.106 , Issue.13 , pp. 4066-7405
    • Richardson, J.L.1    Shivdasani, R.A.2    Boers, C.3    Hartwig, J.H.4    Italino, E.J.5
  • 24
    • 80455140580 scopus 로고    scopus 로고
    • Regulators of G protein signaling (RGS) proteins as drug targets: Modulating G-protein-coupled receptor (GPCR) signal transduction
    • Roman, D.L.; Traynor, J.R. Regulators of G protein signaling (RGS) proteins as drug targets: modulating G-protein-coupled receptor (GPCR) signal transduction. J. Med. Chem., 2011, 54(21), 7433-7440.
    • (2011) J. Med. Chem , vol.54 , Issue.21 , pp. 7433-7440
    • Roman, D.L.1    Traynor, J.R.2
  • 25
    • 0030872993 scopus 로고    scopus 로고
    • Identification of PDGF receptors on human megakaryocytes and megakaryocytic cell lines
    • Yang, M.; Khachigian, L.M.; Hicks, C.; Chesterman, C.N.; Chong, B.H. Identification of PDGF receptors on human megakaryocytes and megakaryocytic cell lines. Thromb. Haemost., 1997, 78, 892-896.
    • (1997) Thromb. Haemost , vol.78 , pp. 892-896
    • Yang, M.1    Khachigian, L.M.2    Hicks, C.3    Chesterman, C.N.4    Chong, B.H.5
  • 27
    • 33847044392 scopus 로고    scopus 로고
    • Comparative genome-scale transcriptional analysis of CHRF-288-11 and primary human megakaryocytic cell cultures provides novel insights into lineage-specific differentiation
    • Fuhrken, P.G.; Chen, C.; Miller, W.M.; Papoutsakis, E.T. Comparative, genome-scale transcriptional analysis of CHRF-288-11 and primary human megakaryocytic cell cultures provides novel insights into lineage-specific differentiation. Exp. Hematol., 2007, 35, 476-489.
    • (2007) Exp. Hematol , vol.35 , pp. 476-489
    • Fuhrken, P.G.1    Chen, C.2    Miller, W.M.3    Papoutsakis, E.T.4
  • 28
    • 84856076396 scopus 로고    scopus 로고
    • Pituitary adenylate cyclase-activating polypeptide (pacap) impairs the regulation of apoptosis in megakaryocytes by activating NF-B: A proteomic study
    • Di Michele, M.; Peeters, K.; Loyen, S.; Thys, C.; Waelkens, E.; Overbergh, L.; Hoylaerts, M.; Van Geet, C.; Freson, K. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Impairs the Regulation of Apoptosis in Megakaryocytes by Activating NF-B: a Proteomic Study. Mol. Cell. Proteomics, 2012, 11(1), M111.007625.
    • (2012) Mol. Cell. Proteomics , vol.11 , Issue.1
    • Di Michele, M.1    Peeters, K.2    Loyen, S.3    Thys, C.4    Waelkens, E.5    Overbergh, L.6    Hoylaerts, M.7    Van Geet, C.8    Freson, K.9
  • 31
    • 51249100441 scopus 로고    scopus 로고
    • Emerging treatments for thrombocytopenia: Increasing platelet production
    • Peeters, K.; Stassen, J.M.; Collen, D.; Van Geet, C.; Freson, K. Emerging treatments for thrombocytopenia: increasing platelet production. Drug Discov. Today, 2008, 13(17-18), 798-806.
    • (2008) Drug Discov. Today , vol.13 , Issue.17-18 , pp. 798-806
    • Peeters, K.1    Stassen, J.M.2    Collen, D.3    Van Geet, C.4    Freson, K.5
  • 32
    • 79955962512 scopus 로고    scopus 로고
    • Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation
    • Mazharian, A.; Ghevaert, C.; Zhang, L.; Massberg, S.; Watson, S.P. Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation. Blood, 2011, 117(19), 5198-5206.
    • (2011) Blood , vol.117 , Issue.19 , pp. 5198-5206
    • Mazharian, A.1    Ghevaert, C.2    Zhang, L.3    Massberg, S.4    Watson, S.P.5
  • 33
    • 51649130092 scopus 로고    scopus 로고
    • The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes
    • Veldurthy, A.; Patz, M.; Hagist, S.; Pallasch, C.P.; Wendtner, C.M.; Hallek, M.; Krause, G. The kinase inhibitor dasatinib induces apoptosis in chronic lymphocytic leukemia cells in vitro with preference for a subgroup of patients with unmutated IgVH genes. Blood, 2008, 112(4), 1443-1452.
    • (2008) Blood , vol.112 , Issue.4 , pp. 1443-1452
    • Veldurthy, A.1    Patz, M.2    Hagist, S.3    Pallasch, C.P.4    Wendtner, C.M.5    Hallek, M.6    Krause, G.7
  • 34
    • 80052483131 scopus 로고    scopus 로고
    • Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: Possible combinations in solid tumors
    • Montero, J.C.; Seoane, S.; Ocaña, A.; Pandiella, A. Inhibition of SRC family kinases and receptor tyrosine kinases by dasatinib: possible combinations in solid tumors. Clin. Cancer Res., 2011, 17(17), 5546-5552.
    • (2011) Clin. Cancer Res , vol.17 , Issue.17 , pp. 5546-5552
    • Montero, J.C.1    Seoane, S.2    Ocaña, A.3    Pandiella, A.4
  • 35
    • 34250373620 scopus 로고    scopus 로고
    • Chemotherapy-induced thrombocytopenia derives from the selective death of megakaryocyte progenitors and can be rescued by stem cell factor
    • Zeuner, A.; Signore, M.; Martinetti, D.; Bartuccci, M.; Peschle, C.; De Maria, R. Chemotherapy-induced thrombocytopenia derives from the selective death of megakaryocyte progenitors and can be rescued by stem cell factor. Cancer Res., 2007, 67(10), 4767-4773.
    • (2007) Cancer Res , vol.67 , Issue.10 , pp. 4767-4773
    • Zeuner, A.1    Signore, M.2    Martinetti, D.3    Bartuccci, M.4    Peschle, C.5    De Maria, R.6
  • 41
    • 84860251058 scopus 로고    scopus 로고
    • Platelet mitochondrial dysfunction is evident in type 2 diabetes in association with modifications of mitochondrial anti-oxidant stress proteins
    • Avila, C.; Huang, R.J.; Stevens, M.V.; Aponte, A.M.; Tripodi, D.; Kim, K.Y.; Sack, M.N. Platelet Mitochondrial Dysfunction is Evident in Type 2 Diabetes in Association with Modifications of Mitochondrial Anti-Oxidant Stress Proteins. Exp. Clin. Endocrinol. Diabetes, 2011, doi: 10.1055/s-0031-1285833.
    • (2011) Exp. Clin. Endocrinol. Diabetes
    • Avila, C.1    Huang, R.J.2    Stevens, M.V.3    Aponte, A.M.4    Tripodi, D.5    Kim, K.Y.6    Sack, M.N.7
  • 42
    • 44949164776 scopus 로고    scopus 로고
    • Carbonylation of platelet proteins occurs as consequence of oxidative stress and thrombin activation, and is stimulated by ageing and type 2 diabetes
    • Alexandru, N.; Constantin, A.; Popov, D. Carbonylation of platelet proteins occurs as consequence of oxidative stress and thrombin activation, and is stimulated by ageing and type 2 diabetes. Clin. Chem. Lab. Med., 2008, 46, 528-536.
    • (2008) Clin. Chem. Lab. Med , vol.46 , pp. 528-536
    • Alexandru, N.1    Constantin, A.2    Popov, D.3
  • 44
    • 33947266124 scopus 로고    scopus 로고
    • Antithrombotic properties of aspirin and resistance to aspirin: Beyond strictly antiplatelet actions
    • Undas, A.; Brummel-Ziedins, K.E.; Mann, K.G. Antithrombotic properties of aspirin and resistance to aspirin: beyond strictly antiplatelet actions. Blood, 2007, 109(6), 2285-2292.
    • (2007) Blood , vol.109 , Issue.6 , pp. 2285-2292
    • Undas, A.1    Brummel-Ziedins, K.E.2    Mann, K.G.3
  • 45
    • 23044435873 scopus 로고    scopus 로고
    • Variability in response to aspirin: Do we understand the clinical relevance?
    • Campbell, C.L.; Steinhubl, S.R. Variability in response to aspirin: do we understand the clinical relevance? J. Thromb. Haemost., 2005, 3(4), 665-669.
    • (2005) J. Thromb. Haemost , vol.3 , Issue.4 , pp. 665-669
    • Campbell, C.L.1    Steinhubl, S.R.2
  • 49
    • 10444235983 scopus 로고    scopus 로고
    • Clopidogrel resistance: A new chapter in a fastmoving story
    • Wiviott, S.D.; Antman, E.M. Clopidogrel resistance: a new chapter in a fastmoving story. Circulation, 2004, 109(25), 3064-3067.
    • (2004) Circulation , vol.109 , Issue.25 , pp. 3064-3067
    • Wiviott, S.D.1    Antman, E.M.2
  • 51
    • 79952525002 scopus 로고    scopus 로고
    • Sheardependent suppression of platelet thrombus formation by phosphodiesterase 3 inhibition requires low levels of concomitant Gs-coupled receptor stimulation
    • Yoshida, H.; Okamura, Y.; Watanabe, N.; Ikeda, Y.; Handa, M. Sheardependent suppression of platelet thrombus formation by phosphodiesterase 3 inhibition requires low levels of concomitant Gs-coupled receptor stimulation. Thromb. Haemost., 2011, 105(3), 487-495.
    • (2011) Thromb. Haemost , vol.105 , Issue.3 , pp. 487-495
    • Yoshida, H.1    Okamura, Y.2    Watanabe, N.3    Ikeda, Y.4    Handa, M.5
  • 52
    • 84858027237 scopus 로고    scopus 로고
    • Use of cilostazol for secondary stroke prevention: An old dog with new tricks? (March
    • Epub ahead of print
    • Ansara, A.J.; Shiltz, D.L.; Slavens, J.B. Use of Cilostazol for Secondary Stroke Prevention: An Old Dog with New Tricks? (March). Ann. Pharmacother., 2012, Epub ahead of print.
    • (2012) Ann. Pharmacother
    • Ansara, A.J.1    Shiltz, D.L.2    Slavens, J.B.3
  • 54
    • 79952285928 scopus 로고    scopus 로고
    • Neurite outgrowth mediated by translation elongation factor eEF1A1: A target for antiplatelet agent cilostazol
    • Hashimoto, K.; Ishima, T. Neurite outgrowth mediated by translation elongation factor eEF1A1: a target for antiplatelet agent cilostazol. PLoS One, 2011, 6(3), e17431.
    • (2011) PLoS One , vol.6 , Issue.3 , pp. e17431
    • Hashimoto, K.1    Ishima, T.2
  • 57
    • 8144222110 scopus 로고    scopus 로고
    • Anti-glycoprotein VI treatment severely compromises hemostasis in mice with reduced alpha2beta1 levels or concomitant aspirin therapy
    • Grüner, S.; Prostredna, M.; Aktas, B.; Moers, A.; Schulte, V.; Krieg, T.; Offermanns, S.; Eckes, B.; Nieswandt, B. Anti-glycoprotein VI treatment severely compromises hemostasis in mice with reduced alpha2beta1 levels or concomitant aspirin therapy. Circulation, 2004, 110, 2946-2951.
    • (2004) Circulation , vol.110 , pp. 2946-2951
    • Grüner, S.1    Prostredna, M.2    Aktas, B.3    Moers, A.4    Schulte, V.5    Krieg, T.6    Offermanns, S.7    Eckes, B.8    Nieswandt, B.9
  • 58
    • 70350015034 scopus 로고    scopus 로고
    • Proteomic analysis of integrin alphaIIbbeta3 outside-in signaling reveals Src-kinase-independent phosphorylation of Dok-1 and Dok-3 leading to SHIP-1 interactions
    • Senis, Y.A.; Antrobus, R.; Severin, S.; Parguina, A.F.; Rosa, I.; Zitzmann, N.; Watson, S.P.; Garcia, A. Proteomic analysis of integrin alphaIIbbeta3 outside-in signaling reveals Src-kinase-independent phosphorylation of Dok-1 and Dok-3 leading to SHIP-1 interactions. J. Thromb. Haemost. 2009, 7, 1718-1726.
    • (2009) J. Thromb. Haemost , vol.7 , pp. 1718-1726
    • Senis, Y.A.1    Antrobus, R.2    Severin, S.3    Parguina, A.F.4    Rosa, I.5    Zitzmann, N.6    Watson, S.P.7    Garcia, A.8
  • 59
    • 34249692499 scopus 로고    scopus 로고
    • The novel inhibitory receptor G6B is expressed on the surface of platelets and attenuates platelet function in vitro
    • Newland, S.A.; Macaulay, I.C.; Floto, A.R.; de Vet, E.C.; Ouwehand, W.H.; Watkins, N.A.; Lyons, P.A.; Campbell, D.R. The novel inhibitory receptor G6B is expressed on the surface of platelets and attenuates platelet function in vitro. Blood, 2007, 109(11), 4806-4809.
    • (2007) Blood , vol.109 , Issue.11 , pp. 4806-4809
    • Newland, S.A.1    Macaulay, I.C.2    Floto, A.R.3    De Vet, E.C.4    Ouwehand, W.H.5    Watkins, N.A.6    Lyons, P.A.7    Campbell, D.R.8
  • 61
    • 70349125020 scopus 로고    scopus 로고
    • Proteomic analysis of resting and thrombin-stimulated platelets reveals the translocation and functional relevance of HIP-55 in platelets
    • Tucker, K.L.; Kaiser, W.J.; Bergeron, A.L.; Hu, H.; Dong, J.F.; Tan, T.H.; Gibbins, J.M. Proteomic analysis of resting and thrombin-stimulated platelets reveals the translocation and functional relevance of HIP-55 in platelets. Proteomics, 2009, 9(18), 4340-4354.
    • (2009) Proteomics , vol.9 , Issue.18 , pp. 4340-4354
    • Tucker, K.L.1    Kaiser, W.J.2    Bergeron, A.L.3    Hu, H.4    Dong, J.F.5    Tan, T.H.6    Gibbins, J.M.7
  • 62
    • 69949110846 scopus 로고    scopus 로고
    • Proteomic identification of pleckstrin associated proteins in platelets: Possible interactions with actin
    • Baig, A.; Bao, X.; Haslam, R.J. Proteomic identification of pleckstrin associated proteins in platelets: possible interactions with actin. Proteomics 2009, 9(17), 4254-4258.
    • (2009) Proteomics , vol.9 , Issue.17 , pp. 4254-4258
    • Baig, A.1    Bao, X.2    Haslam, R.J.3
  • 65
    • 12144291702 scopus 로고    scopus 로고
    • Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions
    • Coppinger, J.A.; Cagney, G.; Toomey, S.; Kislinger, T.; Belton, O.; McRedmond, J.P.; Cahill, D.J.; Emili, A.; Fitzgerald, D.J.; Maguire, P.B. Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions. Blood, 2004, 103, 2096-2104.
    • (2004) Blood , vol.103 , pp. 2096-2104
    • Coppinger, J.A.1    Cagney, G.2    Toomey, S.3    Kislinger, T.4    Belton, O.5    McRedmond, J.P.6    Cahill, D.J.7    Emili, A.8    Fitzgerald, D.J.9    Maguire, P.B.10
  • 66
    • 0034691108 scopus 로고    scopus 로고
    • Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice
    • Schonbeck, U.; Sukhova, G.K.; Shimizu, K.; Mach, F.; Libby, P. Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice. Proc. Natl. Acad. Sci. U S A, 2000, 97, 7458-7463.
    • (2000) Proc. Natl. Acad. Sci. U S A , vol.97 , pp. 7458-7463
    • Schonbeck, U.1    Sukhova, G.K.2    Shimizu, K.3    Mach, F.4    Libby, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.