Platelet Gs hypofunction and abnormal morphology resulting from a heterozygous RGS2 mutation

Journal of Thrombosis and Haemostasis

Volumn 8, Issue 7, 2010, Pages 1594-1603

  Noe L ^a   Di Michele, M ^a   Giets, E ^a   Thys, C ^a   Wittevrongel, C ^a   De Vos, R ^b   Overbergh, L ^c   Waelkens, E ^d   Jaeken, J ^c   Van Geet, C ^a,c   Freson, K ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b Department of Pathology ^*  (Belgium)

^c UNIVERSITY OF LEUVEN   (Belgium)

^d LABORATORY OF MOLECULAR AND CELLULAR SIGNALING   (Belgium)

Author keywords

CAMP production; Gs signaling; Platelet function; Regulator of G protein signaling 2; Translation initiation

Indexed keywords

ACTIN; CYCLIC AMP; RGS2 PROTEIN;

ARTICLE; CELL STRUCTURE; EX VIVO STUDY; GENE MUTATION; GENETIC SCREENING; GENETIC TRANSFECTION; HETEROZYGOSITY; HETEROZYGOTE; HUMAN; IMMUNOPRECIPITATION; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEOMICS; SIGNAL TRANSDUCTION; THROMBOCYTE FUNCTION;

ADENYLATE CYCLASE; BLOOD PLATELETS; CELL SHAPE; GTP-BINDING PROTEINS; HETEROZYGOTE; HUMANS; MUTATION, MISSENSE; PROTEIN BIOSYNTHESIS; PROTEIN ISOFORMS; RGS PROTEINS; SIGNAL TRANSDUCTION;

EID: 77955019954     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2010.03885.x     Document Type: Article

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